Characterization of the Drosophila insulin receptor promoter

Biochimica et Biophysica Acta - Gene Structure and Expression

Volumn 1769, Issue 4, 2007, Pages 236-243

  Casas Tinto, Sergio ^a,b   Marr II, Michael T ^c   Andreu, Pedro ^a   Puig, Oscar ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Diabetes; Drosophila melanogaster; Insulin receptor; Transcription

Indexed keywords

INSULIN RECEPTOR; MESSENGER RNA;

5' UNTRANSLATED REGION; ARTICLE; CONTROLLED STUDY; DROSOPHILA; EMBRYO DEVELOPMENT; EXON; GENE EXPRESSION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BINDING;

5' UNTRANSLATED REGIONS; ANIMALS; DROSOPHILA; GENE EXPRESSION REGULATION, DEVELOPMENTAL; PROMOTER REGIONS (GENETICS); RECEPTOR, INSULIN; RNA, MESSENGER;

DROSOPHILA MELANOGASTER; METAZOA;

EID: 34247845995     PISSN: 01674781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbaexp.2007.03.003     Document Type: Article

References (51)

1. Le Roith D., and Zick Y. Recent advances in our understanding of insulin action and insulin resistance. Diabetes Care 24 (2001) 588
2. Saltiel A.R., and Kahn C.R. Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414 (2001) 799
3. Saltiel A.R. New perspectives into the molecular pathogenesis and treatment of type 2 diabetes. Cell 104 (2001) 517
4. Avruch J. Insulin signal transduction through protein kinase cascades. Mol. Cell. Biochem. 182 (1998) 31
5. Alvarez B., Martinez A., Burgering B.M., and Carrera A.C. Forkhead transcription factors contribute to execution of the mitotic programme in mammals. Nature 413 (2001) 744
6. Brunet A., Bonni A., Zigmond M.J., Lin M.Z., Juo P., Hu L.S., Anderson M.J., Arden K.C., Blenis J., and Greenberg M.E. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96 (1999) 857
7. Biggs III W.H., Meisenhelder J., Hunter T., Cavenee W.K., and Arden K.C. Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 7421
8. Guo S., Rena G., Cichy S., He X., Cohen P., and Unterman T. Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence. J. Biol. Chem. 274 (1999) 17184
9. Nakae J., Park B.C., and Accili D. Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway. J. Biol. Chem. 274 (1999) 15982
10. Rena G., Guo S., Cichy S.C., Unterman T.G., and Cohen P. Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B. J. Biol. Chem. 274 (1999) 17179
11. Tang E.D., Nunez G., Barr F.G., and Guan K.L. Negative regulation of the forkhead transcription factor FKHR by Akt. J. Biol. Chem. 274 (1999) 16741
12. Durham S.K., Suwanichkul A., Scheimann A.O., Yee D., Jackson J.G., Barr F.G., and Powell D.R. FKHR binds the insulin response element in the insulin-like growth factor binding protein-1 promoter. Endocrinology 140 (1999) 3140
13. Hall R.K., Yamasaki T., Kucera T., Waltner-Law M., O'Brien R., and Granner D.K. Regulation of phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein-1 gene expression by insulin. The role of winged helix/forkhead proteins. J. Biol. Chem. 275 (2000) 30169
14. Schmoll D., Walker K.S., Alessi D.R., Grempler R., Burchell A., Guo S., Walther R., and Unterman T.G. Regulation of glucose-6-phosphatase gene expression by protein kinase Balpha and the forkhead transcription factor FKHR. Evidence for insulin response unit-dependent and -independent effects of insulin on promoter activity. J. Biol. Chem. 275 (2000) 36324
15. Hribal M.L., Nakae J., Kitamura T., Shutter J.R., and Accili D. Regulation of insulin-like growth factor-dependent myoblast differentiation by Foxo forkhead transcription factors. J. Cell Biol. 162 (2003) 535
16. Nakae J., Kitamura T., Kitamura Y., Biggs III W.H., Arden K.C., and Accili D. The forkhead transcription factor Foxo1 regulates adipocyte differentiation. Dev. Cell 4 (2003) 119
17. Kitamura T., Nakae J., Kitamura Y., Kido Y., Biggs III W.H., Wright C.V., White M.F., Arden K.C., and Accili D. The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth. J. Clin. Invest. 110 (2002) 1839
18. Lasko P. Diabetic flies? Using Drosophila melanogaster to understand the causes of monogenic and genetically complex diseases. Clin. Genet. 62 (2002) 358
19. Gao X., and Pan D. TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth. Genes Dev. 15 (2001) 1383
20. Harvey K.F., Pfleger C.M., and Hariharan I.K. The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis. Cell 114 (2003) 457
21. Reiling J.H., and Hafen E. The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila. Genes Dev. 18 (2004) 2879
22. Tapon N., Harvey K.F., Bell D.W., Wahrer D.C., Schiripo T.A., Haber D.A., and Hariharan I.K. salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines. Cell 110 (2002) 467
23. Wittwer F., Jaquenoud M., Brogiolo W., Zarske M., Wustemann P., Fernandez R., Stocker H., Wymann M.P., and Hafen E. Susi, a negative regulator of Drosophila PI3-kinase. Dev. Cell 8 (2005) 817
24. Zhang H., Stallock J.P., Ng J.C., Reinhard C., and Neufeld T.P. Regulation of cellular growth by the Drosophila target of rapamycin dTOR. Genes Dev. 14 (2000) 2712
25. Brogiolo W., Stocker H., Ikeya T., Rintelen F., Fernandez R., and Hafen E. An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control. Curr. Biol. 11 (2001) 213
26. Ikeya T., Galic M., Belawat P., Nairz K., and Hafen E. Nutrient-dependent expression of insulin-like peptides from neuroendocrine cells in the CNS contributes to growth regulation in Drosophila. Curr. Biol. 12 (2002) 1293
27. Rulifson E.J., Kim S.K., and Nusse R. Ablation of insulin-producing neurons in flies: growth and diabetic phenotypes. Science 296 (2002) 1118
28. Bohni R., Riesgo-Escovar J., Oldham S., Brogiolo W., Stocker H., Andruss B.F., Beckingham K., and Hafen E. Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4. Cell 97 (1999) 865
29. Chen C., Jack J., and Garofalo R.S. The Drosophila insulin receptor is required for normal growth. Endocrinology 137 (1996) 846
30. Yenush L., Fernandez R., Myers Jr. M.G., Grammer T.C., Sun X.J., Blenis J., Pierce J.H., Schlessinger J., and White M.F. The Drosophila insulin receptor activates multiple signaling pathways but requires insulin receptor substrate proteins for DNA synthesis. Mol. Cell. Biol. 16 (1996) 2509
31. Hafen E. Cancer, type 2 diabetes, and ageing: news from flies and worms. Swiss Med. Wkly. 134 (2004) 711
32. Junger M.A., Rintelen F., Stocker H., Wasserman J.D., Vegh M., Radimerski T., Greenberg M.E., and Hafen E. The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling. J. Biol. 2 (2003) 20
33. Kramer J.M., Davidge J.T., Lockyer J.M., and Staveley B.E. Expression of Drosophila FOXO regulates growth and can phenocopy starvation, BMC. Dev. Biol. 3 (2003) 5
34. Puig O., Marr M.T., Ruhf M.L., and Tjian R. Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway. Genes Dev. 17 (2003) 2006
35. Puig O., and Tjian R. Transcriptional feedback control of insulin receptor by dFOXO/FOXO1. Genes Dev. 19 (2005) 2435
36. Carninci P., Westover A., Nishiyama Y., Ohsumi T., Itoh M., Nagaoka S., Sasaki N., Okazaki Y., Muramatsu M., Schneider C., and Hayashizaki Y. High efficiency selection of full-length cDNA by improved biotinylated cap trapper. DNA Res. 4 (1997) 61
37. Katti M.V., Sakharkar M.K., Ranjekar P.K., and Gupta V.S. TRES: comparative promoter sequence analysis. Bioinformatics 16 (2000) 739
38. Burke T.W., and Kadonaga J.T. The downstream core promoter element, DPE, is conserved from Drosophila to humans and is recognized by TAFII60 of Drosophila. Genes Dev. 11 (1997) 3020
39. Ohler U., Liao G.C., Niemann H., and Rubin G.M. Computational analysis of core promoters in the Drosophila genome. Genome Biol. 3 (2002) (RESEARCH0087)
40. Sanders M.M., Triemer D.F., and Olsen A.S. Regulation of protein synthesis in heat-shocked Drosophila cells. Soluble factors control translation in vitro. J. Biol. Chem. 261 (1986) 2189
41. Pfaffl M.W., Horgan G.W., and Dempfle L. Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res. 30 (2002) e36
42. Ausubel F.M. Current Protocols in Molecular Biology (2003), John Wiley & Sons, Inc
43. Campos-Ortega J.A., and Hartenstein V. The Embryonic Development of Drosophila melanogaster (1985), Springer-Verlag, Berlin
44. Oh S.K., Scott M.P., and Sarnow P. Homeotic gene Antennapedia mRNA contains 5′-noncoding sequences that confer translational initiation by internal ribosome binding. Genes Dev. 6 (1992) 1643
45. Oh S.K., and Sarnow P. Gene regulation: translational initiation by internal ribosome binding. Curr. Opin. Genet. Dev. 3 (1993) 295
46. Fernandez R., Tabarini D., Azpiazu N., Frasch M., and Schlessinger J. The Drosophila insulin receptor homolog: a gene essential for embryonic development encodes two receptor isoforms with different signaling potential. EMBO J. 14 (1995) 3373
47. Garofalo R.S., and Rosen O.M. Tissue localization of Drosophila melanogaster insulin receptor transcripts during development. Mol. Cell. Biol. 8 (1988) 1638
48. Puig O., and Tjian R. Nutrient availability and growth: regulation of insulin signaling by dFOXO/FOXO1. Cell Cycle 5 (2006) 503
49. Araki E., Shimada F., Fukushima H., Mori M., Shichiri M., and Ebina Y. Characterization of the promoter region of the human insulin receptor gene. Diabetes Res. Clin. Pract. 7 Suppl. 1 (1989) S31-S33
50. Cameron K.E., Resnik J., and Webster N.J. Transcriptional regulation of the human insulin receptor promoter. J. Biol. Chem. 267 (1992) 17375
51. McKeon C., Moncada V., Pham T., Salvatore P., Kadowaki T., Accili D., and Taylor S.I. Structural and functional analysis of the insulin receptor promoter. Mol. Endocrinol. 4 (1990) 647