The structure-specific nicking of small heteroduplexes by the RAG complex: Implications for lymphoid chromosomal translocations

DNA Repair

Volumn 6, Issue 6, 2007, Pages 751-759

  Raghavan, Sathees C ^a   Gu, Jiafeng ^b   Swanson, Patrick C ^c   Lieber, Michael R ^b  

^a INDIAN INSTITUTE OF SCIENCE   (India)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c CREIGHTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Chromosomal translocation; non B DNA; RAG; Structure specific nuclease; V(D)J recombination

Indexed keywords

DNA B; HETERODUPLEX; OLIGOMER; RAG1 PROTEIN; RAG2 PROTEIN;

ARTICLE; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; DNA CLEAVAGE; DNA FLANKING REGION; DNA STRUCTURE; ENZYME ACTIVITY; HISTOGRAM; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; PRIORITY JOURNAL;

ANIMALS; CELL LINE; CHROMOSOMES; DNA; DNA-BINDING PROTEINS; HOMEODOMAIN PROTEINS; HUMANS; LYMPHOCYTES; LYMPHOID TISSUE; MICE; MODELS, GENETIC; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES; RECOMBINATION, GENETIC; TRANSLOCATION, GENETIC;

EID: 34247604497     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2006.12.016     Document Type: Article

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