One-step synthesis of heterocyclic privileged medicinal scaffolds by a multicomponent reaction of malononitrile with aldehydes and thiols

Journal of Organic Chemistry

Volumn 72, Issue 9, 2007, Pages 3443-3453

  Evdokimov, Nikolai M ^a   Kireev, Artem S ^b   Yakovenko, Andrey A ^c   Antipin, Mikhail Yu ^c,d   Magedov, Igor V ^a,e   Kornienko, Alexander ^b  

^a RUSSIAN STATE AGRARIAN UNIVERSITY   (Russian Federation)

^b NEW MEXICO INSTITUTE OF MINING AND TECHNOLOGY   (United States)

^c NEW MEXICO HIGHLANDS UNIVERSITY   (United States)

^d A N NESMEYANOV INSTITUTE OF ORGANOELEMENT COMPOUNDS   (Russian Federation)

^e Intelbioscan Ltd   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

DIVERSE LIBRARIES; MALONONITRILE; MULTICOMPONENT REACTIONS; UNENCUMBERED ALDEHYDES;

ALDEHYDES; AROMATIC COMPOUNDS; CHROMATOGRAPHIC ANALYSIS; DIMERS; MEDICINE; OXYGEN; PYRIDINE;

SYNTHESIS (CHEMICAL);

1,4 DIHYDROPYRIDINE; ALDEHYDE; ALDEHYDE DERIVATIVE; CHROMENE DERIVATIVE; CHROMENO[2,3 B]PYRIDINE; DIHYDRO 1,4 DITHIEPINE; DIMER; DITHIOL DERIVATIVE; ETHANE; HETEROCYCLIC COMPOUND; MALONONITRILE; OXYGEN; PYRIDINE; SALICYLALDEHYDE; THIEPIN DERIVATIVE; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; CHEMICAL REACTION; CHEMICAL STRUCTURE; DRUG RESEARCH; DRUG STRUCTURE; DRUG SYNTHESIS; KNOEVENAGEL CONDENSATION; STRUCTURE ANALYSIS;

ALDEHYDES; CHEMISTRY, ORGANIC; COMBINATORIAL CHEMISTRY TECHNIQUES; DIHYDROPYRIDINES; HETEROCYCLIC COMPOUNDS; MOLECULAR STRUCTURE; NITRILES; PYRIDINES; SULFHYDRYL COMPOUNDS; TECHNOLOGY, PHARMACEUTICAL;

EID: 34247579244     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo070114u     Document Type: Article

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