메뉴 건너뛰기




Volumn 69, Issue 1, 2007, Pages 161-165

Adipokines regulate systemic insulin sensitivity in accordance to existing energy reserves

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE KINASE; ADIPOCYTOKINE; ADIPONECTIN; INSULIN RECEPTOR SUBSTRATE 1; LEPTIN; METFORMIN; PHOSPHATIDYLINOSITOL 3 KINASE; TROGLITAZONE;

EID: 34247579096     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2006.10.053     Document Type: Article
Times cited : (5)

References (62)
  • 1
    • 12344277552 scopus 로고    scopus 로고
    • Diabetes, obesity, and the brain
    • Schwartz M.W., and Porte Jr. D. Diabetes, obesity, and the brain. Science 307 (2005) 375-379
    • (2005) Science , vol.307 , pp. 375-379
    • Schwartz, M.W.1    Porte Jr., D.2
  • 2
    • 33748920365 scopus 로고    scopus 로고
    • The pancreatic beta cell is a key site for mediating the effects of leptin on glucose homeostasis
    • Covey S.D., Wideman R.D., McDonald C., Unniappan S., Huynh F., Asadi A., et al. The pancreatic beta cell is a key site for mediating the effects of leptin on glucose homeostasis. Cell Metab 4 (2006) 291-302
    • (2006) Cell Metab , vol.4 , pp. 291-302
    • Covey, S.D.1    Wideman, R.D.2    McDonald, C.3    Unniappan, S.4    Huynh, F.5    Asadi, A.6
  • 3
    • 0033974348 scopus 로고    scopus 로고
    • The adipoinsular axis: effects of leptin on pancreatic beta-cells
    • Kieffer T.J., and Habener J.F. The adipoinsular axis: effects of leptin on pancreatic beta-cells. Am J Physiol 278 (2000) E1-E14
    • (2000) Am J Physiol , vol.278
    • Kieffer, T.J.1    Habener, J.F.2
  • 5
    • 13544266181 scopus 로고    scopus 로고
    • Expression of DGAT2 in white adipose tissue is regulated by central leptin action
    • Suzuki R., Tobe K., Aoyama M., Sakamoto K., Ohsugi M., Kamei N., et al. Expression of DGAT2 in white adipose tissue is regulated by central leptin action. J Biol Chem 280 (2005) 3331-3337
    • (2005) J Biol Chem , vol.280 , pp. 3331-3337
    • Suzuki, R.1    Tobe, K.2    Aoyama, M.3    Sakamoto, K.4    Ohsugi, M.5    Kamei, N.6
  • 6
    • 0040381066 scopus 로고    scopus 로고
    • Leptin impairs metabolic actions of insulin in isolated rat adipocytes
    • Muller G., Ertl J., Gerl M., and Preibisch G. Leptin impairs metabolic actions of insulin in isolated rat adipocytes. J Biol Chem 272 (1997) 10585-10593
    • (1997) J Biol Chem , vol.272 , pp. 10585-10593
    • Muller, G.1    Ertl, J.2    Gerl, M.3    Preibisch, G.4
  • 7
    • 0031708557 scopus 로고    scopus 로고
    • Leptin inhibits insulin-stimulated incorporation of glucose into lipids and stimulates glucose decarboxylation in isolated rat adipocytes
    • Ceddia R.B., William Jr. W.N., Lima F.B., and Curi R. Leptin inhibits insulin-stimulated incorporation of glucose into lipids and stimulates glucose decarboxylation in isolated rat adipocytes. J Endocrinol 158 (1998) R7-R9
    • (1998) J Endocrinol , vol.158
    • Ceddia, R.B.1    William Jr., W.N.2    Lima, F.B.3    Curi, R.4
  • 8
    • 17544382289 scopus 로고    scopus 로고
    • AdipoQ is a novel adipose-specific gene dysregulated in obesity
    • Hu E., Liang P., and Spiegelman B.M. AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem 271 (1996) 10697-10703
    • (1996) J Biol Chem , vol.271 , pp. 10697-10703
    • Hu, E.1    Liang, P.2    Spiegelman, B.M.3
  • 10
    • 0034999667 scopus 로고    scopus 로고
    • Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia
    • Weyer C., Funahashi T., Tanaka S., Hotta K., Matsuzawa Y., Pratley R.E., et al. Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab 86 (2001) 1930-1935
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1930-1935
    • Weyer, C.1    Funahashi, T.2    Tanaka, S.3    Hotta, K.4    Matsuzawa, Y.5    Pratley, R.E.6
  • 11
    • 0034881391 scopus 로고    scopus 로고
    • The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
    • Berg A.H., Combs T.P., Du X., Brownlee M., and Scherer P.E. The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med 7 (2001) 947-953
    • (2001) Nat Med , vol.7 , pp. 947-953
    • Berg, A.H.1    Combs, T.P.2    Du, X.3    Brownlee, M.4    Scherer, P.E.5
  • 12
    • 24744457984 scopus 로고    scopus 로고
    • Adiponectin promotes adipocyte differentiation, insulin sensitivity, and lipid accumulation
    • Fu Y., Luo N., Klein R.L., and Garvey W.T. Adiponectin promotes adipocyte differentiation, insulin sensitivity, and lipid accumulation. J Lipid Res 46 (2005) 1369-1379
    • (2005) J Lipid Res , vol.46 , pp. 1369-1379
    • Fu, Y.1    Luo, N.2    Klein, R.L.3    Garvey, W.T.4
  • 13
    • 0037983775 scopus 로고    scopus 로고
    • Involvement of AMP-activated protein kinase in glucose uptake stimulated by the globular domain of adiponectin in primary rat adipocytes
    • Wu X., Motoshima H., Mahadev K., Stalker T.J., Scalia R., and Goldstein B.J. Involvement of AMP-activated protein kinase in glucose uptake stimulated by the globular domain of adiponectin in primary rat adipocytes. Diabetes 52 (2003) 1355-1363
    • (2003) Diabetes , vol.52 , pp. 1355-1363
    • Wu, X.1    Motoshima, H.2    Mahadev, K.3    Stalker, T.J.4    Scalia, R.5    Goldstein, B.J.6
  • 14
    • 0036851817 scopus 로고    scopus 로고
    • Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
    • Yamauchi T., Kamon J., Minokoshi Y., Ito Y., Waki H., Uchida S., et al. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 8 (2002) 1288-1295
    • (2002) Nat Med , vol.8 , pp. 1288-1295
    • Yamauchi, T.1    Kamon, J.2    Minokoshi, Y.3    Ito, Y.4    Waki, H.5    Uchida, S.6
  • 15
    • 17944365228 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
    • Yamauchi T., Kamon J., Waki H., Terauchi Y., Kubota N., Hara K., et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 7 (2001) 941-946
    • (2001) Nat Med , vol.7 , pp. 941-946
    • Yamauchi, T.1    Kamon, J.2    Waki, H.3    Terauchi, Y.4    Kubota, N.5    Hara, K.6
  • 16
    • 2542419773 scopus 로고    scopus 로고
    • Adipocyte determination- and differentiation-dependent factor 1 (ADD1)/sterol regulatory element binding protein 1c (SREBP1c) regulates mouse adiponectin expression
    • Seo J.B., Moon H.M., Noh M.J., Lee Y.S., Jeong H.W., Yoo E.J., et al. Adipocyte determination- and differentiation-dependent factor 1 (ADD1)/sterol regulatory element binding protein 1c (SREBP1c) regulates mouse adiponectin expression. J Biol Chem 279 (2004) 22108-22117
    • (2004) J Biol Chem , vol.279 , pp. 22108-22117
    • Seo, J.B.1    Moon, H.M.2    Noh, M.J.3    Lee, Y.S.4    Jeong, H.W.5    Yoo, E.J.6
  • 17
    • 0035462629 scopus 로고    scopus 로고
    • PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein
    • Maeda N., Takahashi M., Funahashi T., Kihara S., Nishizawa H., Kishida K., et al. PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes 50 (2001) 2094-2099
    • (2001) Diabetes , vol.50 , pp. 2094-2099
    • Maeda, N.1    Takahashi, M.2    Funahashi, T.3    Kihara, S.4    Nishizawa, H.5    Kishida, K.6
  • 18
    • 0037677767 scopus 로고    scopus 로고
    • Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors
    • Iwaki M., Matsuda M., Maeda N., Funahashi T., Matsuzawa Y., Makishima M., et al. Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors. Diabetes 52 (2003) 1655-1663
    • (2003) Diabetes , vol.52 , pp. 1655-1663
    • Iwaki, M.1    Matsuda, M.2    Maeda, N.3    Funahashi, T.4    Matsuzawa, Y.5    Makishima, M.6
  • 19
    • 0034891684 scopus 로고    scopus 로고
    • Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin
    • Yang W.S., Lee W.J., Funahashi T., Tanaka S., Matsuzawa Y., Chao C.L., et al. Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin. J Clin Endocrinol Metab 86 (2001) 3815-3819
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3815-3819
    • Yang, W.S.1    Lee, W.J.2    Funahashi, T.3    Tanaka, S.4    Matsuzawa, Y.5    Chao, C.L.6
  • 20
    • 0036789137 scopus 로고    scopus 로고
    • The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects
    • Yu J.G., Javorschi S., Hevener A.L., Kruszynska Y.T., Norman R.A., Sinha M., et al. The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects. Diabetes 51 (2002) 2968-2974
    • (2002) Diabetes , vol.51 , pp. 2968-2974
    • Yu, J.G.1    Javorschi, S.2    Hevener, A.L.3    Kruszynska, Y.T.4    Norman, R.A.5    Sinha, M.6
  • 21
    • 4243645912 scopus 로고    scopus 로고
    • Induction of adipocyte complement-related protein of 30 kilodaltons by PPAR gamma agonists: a potential mechanism of insulin sensitization
    • Combs T.P., Wagner J.A., Berger J., Doebber T., Wang W.J., Zhang B.B., et al. Induction of adipocyte complement-related protein of 30 kilodaltons by PPAR gamma agonists: a potential mechanism of insulin sensitization. Endocrinology 143 (2002) 998-1007
    • (2002) Endocrinology , vol.143 , pp. 998-1007
    • Combs, T.P.1    Wagner, J.A.2    Berger, J.3    Doebber, T.4    Wang, W.J.5    Zhang, B.B.6
  • 22
    • 0036875641 scopus 로고    scopus 로고
    • Direct peripheral effects of ghrelin include suppression of adiponectin expression
    • Ott V., Fasshauer M., Dalski A., Meier B., Perwitz N., Klein H.H., et al. Direct peripheral effects of ghrelin include suppression of adiponectin expression. Horm Metab Res 34 (2002) 640-645
    • (2002) Horm Metab Res , vol.34 , pp. 640-645
    • Ott, V.1    Fasshauer, M.2    Dalski, A.3    Meier, B.4    Perwitz, N.5    Klein, H.H.6
  • 23
    • 23644445507 scopus 로고    scopus 로고
    • Metformin reduces adiponectin protein expression and release in 3T3-L1 adipocytes involving activation of AMP activated protein kinase
    • Huypens P., Quartier E., Pipeleers D., and Van de Casteele M. Metformin reduces adiponectin protein expression and release in 3T3-L1 adipocytes involving activation of AMP activated protein kinase. Eur J Pharmacol 518 (2005) 90-95
    • (2005) Eur J Pharmacol , vol.518 , pp. 90-95
    • Huypens, P.1    Quartier, E.2    Pipeleers, D.3    Van de Casteele, M.4
  • 25
    • 3042670090 scopus 로고    scopus 로고
    • TNFalpha release by the nonfat cells of human adipose tissue
    • Fain J.N., Bahouth S.W., and Madan A.K. TNFalpha release by the nonfat cells of human adipose tissue. Int J Obes Relat Metab Disord 28 4 (2004) 616-622
    • (2004) Int J Obes Relat Metab Disord , vol.28 , Issue.4 , pp. 616-622
    • Fain, J.N.1    Bahouth, S.W.2    Madan, A.K.3
  • 26
    • 2142640818 scopus 로고    scopus 로고
    • 5-Aminoimidazole-4-carboxamide riboside suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of phosphatidylinositol 3-kinase/Akt activation in RAW 264.7 murine macrophages
    • Jhun B.S., Jin Q., Oh Y.T., Kim S.S., Kong Y., Cho Y.H., et al. 5-Aminoimidazole-4-carboxamide riboside suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of phosphatidylinositol 3-kinase/Akt activation in RAW 264.7 murine macrophages. Biochem Biophys Res Commun 318 (2004) 372-380
    • (2004) Biochem Biophys Res Commun , vol.318 , pp. 372-380
    • Jhun, B.S.1    Jin, Q.2    Oh, Y.T.3    Kim, S.S.4    Kong, Y.5    Cho, Y.H.6
  • 28
    • 0036034966 scopus 로고    scopus 로고
    • Identification of regulatory elements in the human adipose most abundant gene transcript-1 (apM-1) promoter: role of SP1/SP3 and TNF-alpha as regulatory pathways
    • Barth N., Langmann T., Scholmerich J., Schmitz G., and Schaffler A. Identification of regulatory elements in the human adipose most abundant gene transcript-1 (apM-1) promoter: role of SP1/SP3 and TNF-alpha as regulatory pathways. Diabetologia 45 (2002) 1425-1433
    • (2002) Diabetologia , vol.45 , pp. 1425-1433
    • Barth, N.1    Langmann, T.2    Scholmerich, J.3    Schmitz, G.4    Schaffler, A.5
  • 29
    • 0036828912 scopus 로고    scopus 로고
    • Profiling gene transcription in vivo reveals adipose tissue as an immediate target of tumor necrosis factor-alpha: implications for insulin resistance
    • Ruan H., Miles P.D., Ladd C.M., Ross K., Golub T.R., Olefsky J.M., et al. Profiling gene transcription in vivo reveals adipose tissue as an immediate target of tumor necrosis factor-alpha: implications for insulin resistance. Diabetes 51 (2002) 3176-3188
    • (2002) Diabetes , vol.51 , pp. 3176-3188
    • Ruan, H.1    Miles, P.D.2    Ladd, C.M.3    Ross, K.4    Golub, T.R.5    Olefsky, J.M.6
  • 30
    • 0037342120 scopus 로고    scopus 로고
    • Modulation of circulating and adipose tissue adiponectin levels by antidiabetic therapy
    • Phillips S.A., Ciaraldi T.P., Kong A.P.S., Bandukwala R., Aroda V., Carter L., et al. Modulation of circulating and adipose tissue adiponectin levels by antidiabetic therapy. Diabetes 52 (2003) 667-674
    • (2003) Diabetes , vol.52 , pp. 667-674
    • Phillips, S.A.1    Ciaraldi, T.P.2    Kong, A.P.S.3    Bandukwala, R.4    Aroda, V.5    Carter, L.6
  • 31
    • 3242745192 scopus 로고    scopus 로고
    • Effects of rosiglitazone and metformin on liver fat content, hepatic insulin resistance, insulin clearance, and gene expression in adipose tissue in patients with type 2 diabetes
    • Tiikkainen M., Hakkinen A.M., Korsheninnikova E., Nyman T., Makimattila S., and Yki-Jarvinen H. Effects of rosiglitazone and metformin on liver fat content, hepatic insulin resistance, insulin clearance, and gene expression in adipose tissue in patients with type 2 diabetes. Diabetes 53 (2004) 2169-2176
    • (2004) Diabetes , vol.53 , pp. 2169-2176
    • Tiikkainen, M.1    Hakkinen, A.M.2    Korsheninnikova, E.3    Nyman, T.4    Makimattila, S.5    Yki-Jarvinen, H.6
  • 32
    • 33749498694 scopus 로고    scopus 로고
    • Initial treatment with rosiglitazone/metformin fixed-dose combination therapy compared with monotherapy with either rosiglitazone or metformin in patients with uncontrolled type 2 diabetes
    • Rosenstock J., Rood J., Cobitz A., Biswas N., Chou H., and Garber A. Initial treatment with rosiglitazone/metformin fixed-dose combination therapy compared with monotherapy with either rosiglitazone or metformin in patients with uncontrolled type 2 diabetes. Diabetes Obes Metab 8 6 (2006) 650-660
    • (2006) Diabetes Obes Metab , vol.8 , Issue.6 , pp. 650-660
    • Rosenstock, J.1    Rood, J.2    Cobitz, A.3    Biswas, N.4    Chou, H.5    Garber, A.6
  • 33
    • 33749455411 scopus 로고    scopus 로고
    • Improvement in glycaemic control with rosiglitazone/metformin fixed-dose combination therapy in patients with type 2 diabetes with very poor glycaemic control
    • Rosenstock J., Rood J., Cobitz A., Huang C., and Garber A. Improvement in glycaemic control with rosiglitazone/metformin fixed-dose combination therapy in patients with type 2 diabetes with very poor glycaemic control. Diabetes Obes Metab 8 6 (2006) 643-649
    • (2006) Diabetes Obes Metab , vol.8 , Issue.6 , pp. 643-649
    • Rosenstock, J.1    Rood, J.2    Cobitz, A.3    Huang, C.4    Garber, A.5
  • 34
    • 33748935337 scopus 로고    scopus 로고
    • A fixed-dose combination of pioglitazone and metformin: a promising alternative in metabolic control
    • Seufert J. A fixed-dose combination of pioglitazone and metformin: a promising alternative in metabolic control. Curr Med Res Opin 22 Suppl. 2 (2006) 39-48
    • (2006) Curr Med Res Opin , vol.22 , Issue.SUPPL. 2 , pp. 39-48
    • Seufert, J.1
  • 35
    • 27744446892 scopus 로고    scopus 로고
    • Treating insulin resistance in type 2 diabetes with metformin and thiazolidinediones
    • Bailey C.J. Treating insulin resistance in type 2 diabetes with metformin and thiazolidinediones. Diabetes Obes Metab 7 (2005) 675-691
    • (2005) Diabetes Obes Metab , vol.7 , pp. 675-691
    • Bailey, C.J.1
  • 36
    • 2942598477 scopus 로고    scopus 로고
    • Stumvoll M. Control of glycaemia: from molecules to men. Minkowski Lecture 2003. Diabetologia 2004;47:770-81.
  • 37
    • 0036310147 scopus 로고    scopus 로고
    • Impaired ('diabetic') insulin signaling and action occur in fat cells long before glucose intolerance-is insulin resistance initiated in the adipose tissue?
    • Smith U. Impaired ('diabetic') insulin signaling and action occur in fat cells long before glucose intolerance-is insulin resistance initiated in the adipose tissue?. Int J Obes Relat Metab Disord 26 (2002) 897-904
    • (2002) Int J Obes Relat Metab Disord , vol.26 , pp. 897-904
    • Smith, U.1
  • 38
    • 0032762661 scopus 로고    scopus 로고
    • Insulin signaling and action in fat cells: associations with insulin resistance and type 2 diabetes
    • Smith U., Axelsen M., Carvalho E., Eliasson B., Jansson P.A., and Wesslau C. Insulin signaling and action in fat cells: associations with insulin resistance and type 2 diabetes. Ann N Y Acad Sci 892 (1999) 119-126
    • (1999) Ann N Y Acad Sci , vol.892 , pp. 119-126
    • Smith, U.1    Axelsen, M.2    Carvalho, E.3    Eliasson, B.4    Jansson, P.A.5    Wesslau, C.6
  • 39
    • 33745747676 scopus 로고    scopus 로고
    • A novel leptin signalling pathway via PTEN inhibition in hypothalamic cell lines and pancreatic beta-cells
    • Ning K., Miller L.C., Laidlaw H.A., Burgess L.A., Perera N.M., Downes C.P., et al. A novel leptin signalling pathway via PTEN inhibition in hypothalamic cell lines and pancreatic beta-cells. EMBO J 25 (2006) 2377-2387
    • (2006) EMBO J , vol.25 , pp. 2377-2387
    • Ning, K.1    Miller, L.C.2    Laidlaw, H.A.3    Burgess, L.A.4    Perera, N.M.5    Downes, C.P.6
  • 40
    • 0028845877 scopus 로고
    • Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
    • Maffei M., Halaas J., Ravussin E., Pratley R.E., Lee G.H., Zhang Y., et al. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1 (1995) 1155-1161
    • (1995) Nat Med , vol.1 , pp. 1155-1161
    • Maffei, M.1    Halaas, J.2    Ravussin, E.3    Pratley, R.E.4    Lee, G.H.5    Zhang, Y.6
  • 41
    • 0028793697 scopus 로고
    • Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action
    • Frederich R.C., Hamann A., Anderson S., Lollmann B., Lowell B.B., and Flier J.S. Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action. Nat Med 1 (1995) 1311-1314
    • (1995) Nat Med , vol.1 , pp. 1311-1314
    • Frederich, R.C.1    Hamann, A.2    Anderson, S.3    Lollmann, B.4    Lowell, B.B.5    Flier, J.S.6
  • 42
    • 0036678916 scopus 로고    scopus 로고
    • Inverse relationship between plasma adiponectin and leptin concentrations in normal-weight and obese women
    • Matsubara M., Maruoka S., and Katayose S. Inverse relationship between plasma adiponectin and leptin concentrations in normal-weight and obese women. Eur J Endocrinol 147 (2002) 173-180
    • (2002) Eur J Endocrinol , vol.147 , pp. 173-180
    • Matsubara, M.1    Maruoka, S.2    Katayose, S.3
  • 43
    • 0033515459 scopus 로고    scopus 로고
    • Modulation of insulin receptor substrate-1 tyrosine phosphorylation by an Akt/phosphatidylinositol 3-kinase pathway
    • Li J., DeFea K., and Roth R.A. Modulation of insulin receptor substrate-1 tyrosine phosphorylation by an Akt/phosphatidylinositol 3-kinase pathway. J Biol Chem 274 (1999) 9351-9356
    • (1999) J Biol Chem , vol.274 , pp. 9351-9356
    • Li, J.1    DeFea, K.2    Roth, R.A.3
  • 44
    • 0344686538 scopus 로고    scopus 로고
    • MAP kinases and mTOR mediate insulin-induced phosphorylation of insulin receptor substrate-1 on serine residues 307, 612 and 632
    • Gual P., Gremeaux T., Gonzalez T., Le Marchand-Brustel Y., and Tanti J.F. MAP kinases and mTOR mediate insulin-induced phosphorylation of insulin receptor substrate-1 on serine residues 307, 612 and 632. Diabetologia 46 (2003) 1532-1542
    • (2003) Diabetologia , vol.46 , pp. 1532-1542
    • Gual, P.1    Gremeaux, T.2    Gonzalez, T.3    Le Marchand-Brustel, Y.4    Tanti, J.F.5
  • 45
    • 16844370268 scopus 로고    scopus 로고
    • Regulation of insulin signalling by hyperinsulinaemia: role of IRS-1/2 serine phosphorylation and the mTOR/p70 S6K pathway
    • Ueno M., Carvalheira J.B., Tambascia R.C., Bezerra R.M., Amaral M.E., Carneiro E.M., et al. Regulation of insulin signalling by hyperinsulinaemia: role of IRS-1/2 serine phosphorylation and the mTOR/p70 S6K pathway. Diabetologia 48 (2005) 506-518
    • (2005) Diabetologia , vol.48 , pp. 506-518
    • Ueno, M.1    Carvalheira, J.B.2    Tambascia, R.C.3    Bezerra, R.M.4    Amaral, M.E.5    Carneiro, E.M.6
  • 46
    • 14244252683 scopus 로고    scopus 로고
    • Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes
    • Tremblay F., Gagnon A., Veilleux A., Sorisky A., and Marette A. Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes. Endocrinology 146 (2005) 1328-1337
    • (2005) Endocrinology , vol.146 , pp. 1328-1337
    • Tremblay, F.1    Gagnon, A.2    Veilleux, A.3    Sorisky, A.4    Marette, A.5
  • 47
    • 33845624556 scopus 로고    scopus 로고
    • Leptin down-regulates insulin action through phosphorylation of serine-318 in insulin receptor substrate 1
    • Hennige A.M., Stefan N., Kapp K., Lehmann R., Weigert C., Beck A., et al. Leptin down-regulates insulin action through phosphorylation of serine-318 in insulin receptor substrate 1. FASEB J 20 (2006) 1206-1208
    • (2006) FASEB J , vol.20 , pp. 1206-1208
    • Hennige, A.M.1    Stefan, N.2    Kapp, K.3    Lehmann, R.4    Weigert, C.5    Beck, A.6
  • 48
    • 0036298262 scopus 로고    scopus 로고
    • Rapamycin partially prevents insulin resistance induced by chronic insulin treatment
    • Berg C.E., Lavan B.E., and Rondinone C.M. Rapamycin partially prevents insulin resistance induced by chronic insulin treatment. Biochem Biophys Res Commun 293 (2002) 1021-1027
    • (2002) Biochem Biophys Res Commun , vol.293 , pp. 1021-1027
    • Berg, C.E.1    Lavan, B.E.2    Rondinone, C.M.3
  • 49
    • 0034463918 scopus 로고    scopus 로고
    • A rapamycin-sensitive pathway down-regulates insulin signaling via phosphorylation and proteasomal degradation of insulin receptor substrate-1
    • Haruta T., Uno T., Kawahara J., Takano A., Egawa K., Sharma P.M., et al. A rapamycin-sensitive pathway down-regulates insulin signaling via phosphorylation and proteasomal degradation of insulin receptor substrate-1. Mol Endocrinol 14 (2000) 783-794
    • (2000) Mol Endocrinol , vol.14 , pp. 783-794
    • Haruta, T.1    Uno, T.2    Kawahara, J.3    Takano, A.4    Egawa, K.5    Sharma, P.M.6
  • 50
    • 0036149984 scopus 로고    scopus 로고
    • Molecular mechanism of insulin-induced degradation of insulin receptor substrate 1
    • Zhande R., Mitchell J.J., Wu J., and Sun X.J. Molecular mechanism of insulin-induced degradation of insulin receptor substrate 1. Mol Cell Biol 22 (2002) 1016-1026
    • (2002) Mol Cell Biol , vol.22 , pp. 1016-1026
    • Zhande, R.1    Mitchell, J.J.2    Wu, J.3    Sun, X.J.4
  • 51
    • 0036213626 scopus 로고    scopus 로고
    • Role of mTOR in the degradation of IRS-1: regulation of PP2A activity
    • Hartley D., and Cooper G.M. Role of mTOR in the degradation of IRS-1: regulation of PP2A activity. J Cell Biochem 85 (2002) 304-314
    • (2002) J Cell Biochem , vol.85 , pp. 304-314
    • Hartley, D.1    Cooper, G.M.2
  • 52
    • 33644886769 scopus 로고    scopus 로고
    • Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation
    • Tzatsos A., and Kandror K.V. Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation. Mol Cell Biol 26 1 (2006) 63-76
    • (2006) Mol Cell Biol , vol.26 , Issue.1 , pp. 63-76
    • Tzatsos, A.1    Kandror, K.V.2
  • 54
    • 0030061922 scopus 로고    scopus 로고
    • IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance
    • Hotamisligil G.S., Peraldi P., Budavari A., Ellis R., White M.F., and Spiegelman B.M. IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance. Science 271 (1996) 665-668
    • (1996) Science , vol.271 , pp. 665-668
    • Hotamisligil, G.S.1    Peraldi, P.2    Budavari, A.3    Ellis, R.4    White, M.F.5    Spiegelman, B.M.6
  • 55
    • 33846201363 scopus 로고    scopus 로고
    • Release of interleukins and other inflammatory cytokines by human adipose tissue is enhanced in obesity and primarily due to the nonfat cells
    • Fain J.N. Release of interleukins and other inflammatory cytokines by human adipose tissue is enhanced in obesity and primarily due to the nonfat cells. Vitam Horm 74 (2006) 443-477
    • (2006) Vitam Horm , vol.74 , pp. 443-477
    • Fain, J.N.1
  • 57
    • 33344459071 scopus 로고    scopus 로고
    • Globular adiponectin decreases leptin-induced tumor necrosis factor-alpha expression by murine macrophages: Involvement of cAMP-PKA and MAPK pathways
    • Zhao T., Hou M., Xia M., Wang Q., Zhu H., Xiao Y., et al. Globular adiponectin decreases leptin-induced tumor necrosis factor-alpha expression by murine macrophages: Involvement of cAMP-PKA and MAPK pathways. Cell Immunol 238 (2006) 19-30
    • (2006) Cell Immunol , vol.238 , pp. 19-30
    • Zhao, T.1    Hou, M.2    Xia, M.3    Wang, Q.4    Zhu, H.5    Xiao, Y.6
  • 58
    • 0034641647 scopus 로고    scopus 로고
    • Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway
    • Ouchi N., Kihara S., Arita Y., Okamoto Y., Maeda K., Kuriyama H., et al. Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway. Circulation 102 (2000) 1296-1301
    • (2000) Circulation , vol.102 , pp. 1296-1301
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3    Okamoto, Y.4    Maeda, K.5    Kuriyama, H.6
  • 59
    • 0033613545 scopus 로고    scopus 로고
    • Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin
    • Ouchi N., Kihara S., Arita Y., Maeda K., Kuriyama H., Okamoto Y., et al. Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation 100 (1999) 2473-2476
    • (1999) Circulation , vol.100 , pp. 2473-2476
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3    Maeda, K.4    Kuriyama, H.5    Okamoto, Y.6
  • 61
    • 0028825748 scopus 로고
    • Tumor necrosis factor alpha-induced phosphorylation of insulin receptor substrate-1 (IRS-1). Possible mechanism for suppression of insulin-stimulated tyrosine phosphorylation of IRS-1
    • Kanety H., Feinstein R., Papa M.Z., Hemi R., and Karasik A. Tumor necrosis factor alpha-induced phosphorylation of insulin receptor substrate-1 (IRS-1). Possible mechanism for suppression of insulin-stimulated tyrosine phosphorylation of IRS-1. J Biol Chem 270 (1995) 23780-23784
    • (1995) J Biol Chem , vol.270 , pp. 23780-23784
    • Kanety, H.1    Feinstein, R.2    Papa, M.Z.3    Hemi, R.4    Karasik, A.5
  • 62
    • 3142701401 scopus 로고    scopus 로고
    • Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity
    • Tsuchida A., Yamauchi T., Ito Y., Hada Y., Maki T., Takekawa S., et al. Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity. J Biol Chem 279 (2004) 30817-30822
    • (2004) J Biol Chem , vol.279 , pp. 30817-30822
    • Tsuchida, A.1    Yamauchi, T.2    Ito, Y.3    Hada, Y.4    Maki, T.5    Takekawa, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.