-
1
-
-
0034641936
-
-
Yuan J, Yankner BA. Apoptosis in the nervous system. Nature 2000; 407: 802-809.
-
Yuan J, Yankner BA. Apoptosis in the nervous system. Nature 2000; 407: 802-809.
-
-
-
-
2
-
-
0032192529
-
Evidence of a novel event during neuronal death: Development of competence-to-die in response to cytoplasmic cytochrome c
-
Deshmukh M, Johnson Jr EM. Evidence of a novel event during neuronal death: Development of competence-to-die in response to cytoplasmic cytochrome c. Neuron 1998; 21: 695-705.
-
(1998)
Neuron
, vol.21
, pp. 695-705
-
-
Deshmukh, M.1
Johnson Jr, E.M.2
-
3
-
-
0035890085
-
The expanding role of mitochondria in apoptosis
-
Wang X. The expanding role of mitochondria in apoptosis. Genes Dev 2001; 15: 2922-2933.
-
(2001)
Genes Dev
, vol.15
, pp. 2922-2933
-
-
Wang, X.1
-
4
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
-
Liu X, Kim CN, Yang J, Jemmerson R, Wang X. Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c. Cell 1996; 86: 147-157.
-
(1996)
Cell
, vol.86
, pp. 147-157
-
-
Liu, X.1
Kim, C.N.2
Yang, J.3
Jemmerson, R.4
Wang, X.5
-
5
-
-
7244245454
-
Decreased apoptosome activity with neuronal differentiation sets the threshold for strict IAP regulation of apoptosis
-
Wright KM, Linhoff MW, Potts PR, Deshmukh M. Decreased apoptosome activity with neuronal differentiation sets the threshold for strict IAP regulation of apoptosis. J Cell Biol 2004; 167: 303-313.
-
(2004)
J Cell Biol
, vol.167
, pp. 303-313
-
-
Wright, K.M.1
Linhoff, M.W.2
Potts, P.R.3
Deshmukh, M.4
-
6
-
-
0342978014
-
Cell-specific induction of apoptosis by microinjection of cytochrome c. Bcl-XL has activity independent of cytochrome c release
-
Li F, Srinivasan A, Wang Y, Armstrong RC, Tomaselli KJ, Fritz LC. Cell-specific induction of apoptosis by microinjection of cytochrome c. Bcl-XL has activity independent of cytochrome c release. J Biol Chem 1997; 272: 30299-30305.
-
(1997)
J Biol Chem
, vol.272
, pp. 30299-30305
-
-
Li, F.1
Srinivasan, A.2
Wang, Y.3
Armstrong, R.C.4
Tomaselli, K.J.5
Fritz, L.C.6
-
7
-
-
0031845008
-
Apoptosis induced by microinjection of cytochrome c is caspase-dependent and is inhibited by Bcl-2
-
Brustugun OT, Fladmark KE, Doskeland SO, Orrenius S, Zhivotovsky B. Apoptosis induced by microinjection of cytochrome c is caspase-dependent and is inhibited by Bcl-2. Cell Death Differ 1998; 5: 660-668.
-
(1998)
Cell Death Differ
, vol.5
, pp. 660-668
-
-
Brustugun, O.T.1
Fladmark, K.E.2
Doskeland, S.O.3
Orrenius, S.4
Zhivotovsky, B.5
-
8
-
-
0033152390
-
c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release
-
Juin P, Hueber AO, Littlewood T, Evan G. c-Myc-induced sensitization to apoptosis is mediated through cytochrome c release. Genes Dev 1999; 13: 1367-1381.
-
(1999)
Genes Dev
, vol.13
, pp. 1367-1381
-
-
Juin, P.1
Hueber, A.O.2
Littlewood, T.3
Evan, G.4
-
9
-
-
29144469495
-
Reduced Apaf-1 levels in cardiomyocytes engage strict regulation of apoptosis by endogenous XIAP
-
Potts MB, Vaughn AE, McDonough H, Patterson C, Deshmukh M. Reduced Apaf-1 levels in cardiomyocytes engage strict regulation of apoptosis by endogenous XIAP. J Cell Biol 2005; 171: 925-930.
-
(2005)
J Cell Biol
, vol.171
, pp. 925-930
-
-
Potts, M.B.1
Vaughn, A.E.2
McDonough, H.3
Patterson, C.4
Deshmukh, M.5
-
10
-
-
3843082959
-
Differentiation-dependent sensitivity to apoptogenic factors in PC12 cells
-
Vyas S, Juin P, Hancock D, Suzuki Y, Takahashi R, Triller A et al. Differentiation-dependent sensitivity to apoptogenic factors in PC12 cells. J Biol Chem 2004; 279: 30983-30993.
-
(2004)
J Biol Chem
, vol.279
, pp. 30983-30993
-
-
Vyas, S.1
Juin, P.2
Hancock, D.3
Suzuki, Y.4
Takahashi, R.5
Triller, A.6
-
11
-
-
0344304552
-
Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis
-
Potts PR, Singh S, Knezek M, Thompson CB, Deshmukh M. Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis. J Cell Biol 2003; 163: 789-799.
-
(2003)
J Cell Biol
, vol.163
, pp. 789-799
-
-
Potts, P.R.1
Singh, S.2
Knezek, M.3
Thompson, C.B.4
Deshmukh, M.5
-
12
-
-
0036088471
-
IAP proteins: Blocking the road to death's door
-
Salvesen GS, Duckett CS. IAP proteins: Blocking the road to death's door. Nat Rev Mol Cell Biol 2002; 3: 401-410.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 401-410
-
-
Salvesen, G.S.1
Duckett, C.S.2
-
13
-
-
0041411075
-
Cytosine arabinoside rapidly activates Bax-dependent apoptosis and a delayed Bax-independent death pathway in sympathetic neurons
-
Besirli CG, Deckwerth TL, Crowder RJ, Freeman RS, Johnson Jr EM. Cytosine arabinoside rapidly activates Bax-dependent apoptosis and a delayed Bax-independent death pathway in sympathetic neurons. Cell Death Differ 2003; 10: 1045-1058.
-
(2003)
Cell Death Differ
, vol.10
, pp. 1045-1058
-
-
Besirli, C.G.1
Deckwerth, T.L.2
Crowder, R.J.3
Freeman, R.S.4
Johnson Jr, E.M.5
-
14
-
-
33645100728
-
The BH3-only protein Puma is both necessary and sufficient for neuronal apoptosis induced by DNA damage in sympathetic neurons
-
Wyttenbach A, Tolkovsky AM. The BH3-only protein Puma is both necessary and sufficient for neuronal apoptosis induced by DNA damage in sympathetic neurons. J Neurochem 2006; 96: 1213-1226.
-
(2006)
J Neurochem
, vol.96
, pp. 1213-1226
-
-
Wyttenbach, A.1
Tolkovsky, A.M.2
-
15
-
-
0030995802
-
Programmed cell death in neurons: Focus on the pathway of nerve growth factor deprivation-induced death of sympathetic neurons
-
Deshmukh M, Johnson Jr EM. Programmed cell death in neurons: Focus on the pathway of nerve growth factor deprivation-induced death of sympathetic neurons. Mol Pharm 1997; 51: 897-906.
-
(1997)
Mol Pharm
, vol.51
, pp. 897-906
-
-
Deshmukh, M.1
Johnson Jr, E.M.2
-
16
-
-
0037263789
-
p53-dependent cell death signaling in neurons
-
Morrison RS, Kinoshita Y, Johnson MD, Guo W, Garden GA. p53-dependent cell death signaling in neurons. Neurochem Res 2003; 28: 15-27.
-
(2003)
Neurochem Res
, vol.28
, pp. 15-27
-
-
Morrison, R.S.1
Kinoshita, Y.2
Johnson, M.D.3
Guo, W.4
Garden, G.A.5
-
17
-
-
0019792604
-
Central nervous system toxicity of high-dose systemic cytosine arabinoside
-
Lazarus HM, Herzig RH, Herzig GP, Phillips GL, Roessmann U, Fishman DJ. Central nervous system toxicity of high-dose systemic cytosine arabinoside. Cancer 1981; 48: 2577-2582.
-
(1981)
Cancer
, vol.48
, pp. 2577-2582
-
-
Lazarus, H.M.1
Herzig, R.H.2
Herzig, G.P.3
Phillips, G.L.4
Roessmann, U.5
Fishman, D.J.6
-
19
-
-
0033781632
-
Neuronal life and death: An essential role for the p53 family
-
Miller FD, Pozniak CD, Walsh GS. Neuronal life and death: An essential role for the p53 family. Cell Death Differ 2000; 7: 880-888.
-
(2000)
Cell Death Differ
, vol.7
, pp. 880-888
-
-
Miller, F.D.1
Pozniak, C.D.2
Walsh, G.S.3
-
20
-
-
0035206383
-
Mechanisms of p53-dependent apoptosis
-
Schuler M, Green DR. Mechanisms of p53-dependent apoptosis. Biochem Soc Trans 2001; 29: 684-688.
-
(2001)
Biochem Soc Trans
, vol.29
, pp. 684-688
-
-
Schuler, M.1
Green, D.R.2
-
21
-
-
0034717014
-
Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling
-
Marchenko ND, Zaika A, Moll UM. Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling. J Biol Chem 2000; 275: 16202-16212.
-
(2000)
J Biol Chem
, vol.275
, pp. 16202-16212
-
-
Marchenko, N.D.1
Zaika, A.2
Moll, U.M.3
-
22
-
-
0842278331
-
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
-
Chipuk JE, Kuwana T, Bouchier-Hayes L, Droin NM, Newmeyer DD, Schuler M et al. Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science 2004; 303: 1010-1014.
-
(2004)
Science
, vol.303
, pp. 1010-1014
-
-
Chipuk, J.E.1
Kuwana, T.2
Bouchier-Hayes, L.3
Droin, N.M.4
Newmeyer, D.D.5
Schuler, M.6
-
23
-
-
33847026754
-
Apoptosome dependent caspase-3 activation pathway is non-redundant and necessary for apoptosis in sympathetic neurons
-
August 25, doi:10.1038/sj.cdd.4402024
-
Wright KM, Vaughn AE, Deshmukh M. Apoptosome dependent caspase-3 activation pathway is non-redundant and necessary for apoptosis in sympathetic neurons. Cell Death Differ 2006; AOP, August 25, 2006; doi:10.1038/sj.cdd.4402024.
-
(2006)
Cell Death Differ 2006; AOP
-
-
Wright, K.M.1
Vaughn, A.E.2
Deshmukh, M.3
-
24
-
-
0035889087
-
APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death
-
Fortin A, Cregan SP, MacLaurin JG, Kushwaha N, Hickman ES, Thompson CS et al. APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death. J Cell Biol 2001; 155: 207-216.
-
(2001)
J Cell Biol
, vol.155
, pp. 207-216
-
-
Fortin, A.1
Cregan, S.P.2
MacLaurin, J.G.3
Kushwaha, N.4
Hickman, E.S.5
Thompson, C.S.6
-
25
-
-
0035478060
-
Differential expression of apoptotic protease-activating factor-1 and caspase-3 genes and susceptibility to apoptosis during brain development and after traumatic brain injury
-
Yakovlev AG, Ota K, Wang G, Movsesyan V, Bao W-L, Yoshihara K et al. Differential expression of apoptotic protease-activating factor-1 and caspase-3 genes and susceptibility to apoptosis during brain development and after traumatic brain injury. J Neurosci 2001; 21: 7439-7446.
-
(2001)
J Neurosci
, vol.21
, pp. 7439-7446
-
-
Yakovlev, A.G.1
Ota, K.2
Wang, G.3
Movsesyan, V.4
Bao, W.-L.5
Yoshihara, K.6
-
26
-
-
0034640281
-
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
Oda E, Ohki R, Murasawa H, Nemoto J, Shibue T, Yamashita T et al. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 2000; 288: 1053-1058.
-
(2000)
Science
, vol.288
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
Nemoto, J.4
Shibue, T.5
Yamashita, T.6
-
27
-
-
0037452759
-
PUMA mediates the apoptotic response to p53 in colorectal cancer cells
-
Yu J, Wang Z, Kinzler KW, Vogelstein B, Zhang L. PUMA mediates the apoptotic response to p53 in colorectal cancer cells. Proc Natl Acad Sci USA 2003; 100: 1931-1936.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1931-1936
-
-
Yu, J.1
Wang, Z.2
Kinzler, K.W.3
Vogelstein, B.4
Zhang, L.5
-
28
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita T, Reed JC. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 1995; 80: 293-299.
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
29
-
-
24644436766
-
PUMA couples the nuclear and cytoplasmic proapoptotic function of p53
-
Chipuk JE, Bouchier-Hayes L, Kuwana T, Newmeyer DD, Green DR. PUMA couples the nuclear and cytoplasmic proapoptotic function of p53. Science 2005; 309: 1732-1735.
-
(2005)
Science
, vol.309
, pp. 1732-1735
-
-
Chipuk, J.E.1
Bouchier-Hayes, L.2
Kuwana, T.3
Newmeyer, D.D.4
Green, D.R.5
-
30
-
-
0037349289
-
p53 has a direct apoptogenic role at the mitochondria
-
Mihara M, Erster S, Zaika A, Petrenko O, Chittenden T, Pancoska P et al. p53 has a direct apoptogenic role at the mitochondria. Mol Cell 2003; 11: 577-590.
-
(2003)
Mol Cell
, vol.11
, pp. 577-590
-
-
Mihara, M.1
Erster, S.2
Zaika, A.3
Petrenko, O.4
Chittenden, T.5
Pancoska, P.6
-
31
-
-
0034977277
-
Apaf-1 is a transcriptional target for E2F and p53
-
Moroni MC, Hickman ES, Lazzerini Denchi E, Caprara G, Colli E, Cecconi F et al. Apaf-1 is a transcriptional target for E2F and p53. Nat Cell Biol 2001; 3: 552-558.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 552-558
-
-
Moroni, M.C.1
Hickman, E.S.2
Lazzerini Denchi, E.3
Caprara, G.4
Colli, E.5
Cecconi, F.6
-
32
-
-
0036204018
-
Cell death regulation by the mammalian IAP antagonist Diablo/Smac
-
Verhagen AM, Vaux DL. Cell death regulation by the mammalian IAP antagonist Diablo/Smac. Apoptosis 2002; 7: 163-166.
-
(2002)
Apoptosis
, vol.7
, pp. 163-166
-
-
Verhagen, A.M.1
Vaux, D.L.2
-
34
-
-
0346880501
-
The inhibitors of apoptosis: There is more to life than Bcl2
-
Liston P, Fong WG, Korneluk RG. The inhibitors of apoptosis: There is more to life than Bcl2. Oncogene 2003; 22: 8568-8580.
-
(2003)
Oncogene
, vol.22
, pp. 8568-8580
-
-
Liston, P.1
Fong, W.G.2
Korneluk, R.G.3
-
35
-
-
0034517935
-
p53 is abnormally elevated and active in the CNS of patients with amyotrophic lateral sclerosis
-
Martin LJ. p53 is abnormally elevated and active in the CNS of patients with amyotrophic lateral sclerosis. Neurobiol Dis 2000; 7: 613-622.
-
(2000)
Neurobiol Dis
, vol.7
, pp. 613-622
-
-
Martin, L.J.1
-
36
-
-
0029915857
-
Loss of the p53 tumor suppressor gene protects neurons from kainate-induced cell death
-
Morrison RS, Wenzel HJ, Kinoshita Y, Robbins CA, Donehower LA, Schwartzkroin PA. Loss of the p53 tumor suppressor gene protects neurons from kainate-induced cell death. J Neurosci 1996; 16: 1337-1345.
-
(1996)
J Neurosci
, vol.16
, pp. 1337-1345
-
-
Morrison, R.S.1
Wenzel, H.J.2
Kinoshita, Y.3
Robbins, C.A.4
Donehower, L.A.5
Schwartzkroin, P.A.6
-
37
-
-
0027985453
-
Attenuation of p53 expression protects against focal ischemic damage in transgenic mice
-
Crumrine RC, Thomas AL, Morgan PF. Attenuation of p53 expression protects against focal ischemic damage in transgenic mice. J Cereb Blood Flow Metab 1994; 14: 887-891.
-
(1994)
J Cereb Blood Flow Metab
, vol.14
, pp. 887-891
-
-
Crumrine, R.C.1
Thomas, A.L.2
Morgan, P.F.3
-
38
-
-
0030458720
-
Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE-family proteases
-
Deshmukh M, Vasilakos J, Deckwerth TL, Lampe PA, Shivers BD, Johnson Jr EM. Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE-family proteases. J Cell Biol 1996; 135: 1341-1354.
-
(1996)
J Cell Biol
, vol.135
, pp. 1341-1354
-
-
Deshmukh, M.1
Vasilakos, J.2
Deckwerth, T.L.3
Lampe, P.A.4
Shivers, B.D.5
Johnson Jr, E.M.6
-
39
-
-
0034652010
-
Adult Apaf-1-deficient mice exhibit male infertility
-
Honarpour N, Du C, Richardson JA, Hammer RE, Wang X, Herz J. Adult Apaf-1-deficient mice exhibit male infertility. Dev Biol 2000; 218: 248-258.
-
(2000)
Dev Biol
, vol.218
, pp. 248-258
-
-
Honarpour, N.1
Du, C.2
Richardson, J.A.3
Hammer, R.E.4
Wang, X.5
Herz, J.6
-
40
-
-
0030245811
-
Bax is required for neuronal death after trophic factor deprivation and during development
-
Deckwerth TL, Elliott JL, Knudson CM, Johnson Jr EM, Snider WD, Korsmeyer SJ. Bax is required for neuronal death after trophic factor deprivation and during development. Neuron 1996; 17: 401-411.
-
(1996)
Neuron
, vol.17
, pp. 401-411
-
-
Deckwerth, T.L.1
Elliott, J.L.2
Knudson, C.M.3
Johnson Jr, E.M.4
Snider, W.D.5
Korsmeyer, S.J.6
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