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Volumn 26, Issue 7, 2007, Pages 1782-1793

Suppressor of cytokine signaling 3 controls lysosomal routing of G-CSF receptor

Author keywords

G CSF receptor; Lysosomal routing; Receptor ubiquitination; Signal attenuation; SOCS3

Indexed keywords

CYTOKINE RECEPTOR; GRANULOCYTE COLONY STIMULATING FACTOR RECEPTOR; LYSINE; MITOGEN ACTIVATED PROTEIN KINASE; MUTANT PROTEIN; STAT5 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING; SUPPRESSOR OF CYTOKINE SIGNALING 3;

EID: 34247242299     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601640     Document Type: Article
Times cited : (82)

References (49)
  • 1
    • 0942287735 scopus 로고    scopus 로고
    • Receptor activation and 2 distinct COOH-terminal motifs control G-CSF receptor distribution and internalization kinetics
    • Aarts LH, Roovers O, Ward AC, Touw IP (2004) Receptor activation and 2 distinct COOH-terminal motifs control G-CSF receptor distribution and internalization kinetics. Blood 103: 571-579
    • (2004) Blood , vol.103 , pp. 571-579
    • Aarts, L.H.1    Roovers, O.2    Ward, A.C.3    Touw, I.P.4
  • 2
    • 0035980108 scopus 로고    scopus 로고
    • Growth hormone receptor ubiquitination, endocytosis, and degradation are independent of signal transduction via Janus kinase 2
    • Alves dos Santos CM, ten Broeke T, Strous GJ (2001) Growth hormone receptor ubiquitination, endocytosis, and degradation are independent of signal transduction via Janus kinase 2. J Biol Chem 276: 32635-32641
    • (2001) J Biol Chem , vol.276 , pp. 32635-32641
    • Alves dos Santos, C.M.1    ten Broeke, T.2    Strous, G.J.3
  • 3
    • 0025137532 scopus 로고
    • Human granulocyte colony-stimulating factor: Biologic activities and receptor characterization on hematopoietic cells and small cell lung cancer cell lines
    • Avalos BR, Gasson JC, Hedvat C, Quan SG, Baldwin GC, Weisbart RH, Williams RE, Golde DW, DiPersio JF (1990) Human granulocyte colony-stimulating factor: biologic activities and receptor characterization on hematopoietic cells and small cell lung cancer cell lines. Blood 75: 851-857
    • (1990) Blood , vol.75 , pp. 851-857
    • Avalos, B.R.1    Gasson, J.C.2    Hedvat, C.3    Quan, S.G.4    Baldwin, G.C.5    Weisbart, R.H.6    Williams, R.E.7    Golde, D.W.8    DiPersio, J.F.9
  • 4
    • 0038323973 scopus 로고    scopus 로고
    • STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes
    • Bache KG, Raiborg C, Mehlum A, Stenmark H (2003) STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes. J Biol Chem 278: 12513-12521
    • (2003) J Biol Chem , vol.278 , pp. 12513-12521
    • Bache, K.G.1    Raiborg, C.2    Mehlum, A.3    Stenmark, H.4
  • 5
    • 33644864967 scopus 로고    scopus 로고
    • Ubiquitylation of leptin receptor OB-Ra regulates its clathrin-mediated endocytosis
    • Belouzard S, Rouille Y (2006) Ubiquitylation of leptin receptor OB-Ra regulates its clathrin-mediated endocytosis. EMBO J 25: 932-942
    • (2006) EMBO J , vol.25 , pp. 932-942
    • Belouzard, S.1    Rouille, Y.2
  • 8
    • 0037630266 scopus 로고    scopus 로고
    • Internalization of the thrombopoietin receptor is regulated by 2 cytoplasmic motifs
    • Dahlen DD, Broudy VC, Drachman JG (2003) Internalization of the thrombopoietin receptor is regulated by 2 cytoplasmic motifs. Blood 102: 102-108
    • (2003) Blood , vol.102 , pp. 102-108
    • Dahlen, D.D.1    Broudy, V.C.2    Drachman, J.G.3
  • 9
    • 0030068525 scopus 로고    scopus 로고
    • Specific involvement of tyrosine 764 of human granulocyte colony-stimulating factor receptor in signal transduction mediated by p145/Shc/GRB2 or p90/GRB2 complexes
    • de Koning JP, Schelen AM, Dong F, van Buitenen C, Burgering BM, Bos JL, Lowenberg B, Touw IP (1996) Specific involvement of tyrosine 764 of human granulocyte colony-stimulating factor receptor in signal transduction mediated by p145/Shc/GRB2 or p90/GRB2 complexes. Blood 87: 132-140
    • (1996) Blood , vol.87 , pp. 132-140
    • de Koning, J.P.1    Schelen, A.M.2    Dong, F.3    van Buitenen, C.4    Burgering, B.M.5    Bos, J.L.6    Lowenberg, B.7    Touw, I.P.8
  • 11
    • 0034612529 scopus 로고    scopus 로고
    • STAT3-mediated differentiation and survival and of myeloid cells in response to granulocyte colony-stimulating factor: Role for the cyclindependent kinase inhibitor p27(Kip1)
    • de Koning JP, Soede-Bobok AA, Ward AC, Schelen AM, Antonissen C, van Leeuwen D, Lowenberg B, Touw IP (2000) STAT3-mediated differentiation and survival and of myeloid cells in response to granulocyte colony-stimulating factor: role for the cyclindependent kinase inhibitor p27(Kip1). Oncogene 19: 3290-3298
    • (2000) Oncogene , vol.19 , pp. 3290-3298
    • de Koning, J.P.1    Soede-Bobok, A.A.2    Ward, A.C.3    Schelen, A.M.4    Antonissen, C.5    van Leeuwen, D.6    Lowenberg, B.7    Touw, I.P.8
  • 13
    • 0029961666 scopus 로고    scopus 로고
    • A dileucine motif and an upstream serine in the interleukin-6 (IL-6) signal transducer gp130 mediate ligand-induced endocytosis and down-regulation of the IL-6 receptor
    • Dittrich E, Haft CR, Muys L, Heinrich PC, Graeve L (1996) A dileucine motif and an upstream serine in the interleukin-6 (IL-6) signal transducer gp130 mediate ligand-induced endocytosis and down-regulation of the IL-6 receptor. J Biol Chem 271: 5487-5494
    • (1996) J Biol Chem , vol.271 , pp. 5487-5494
    • Dittrich, E.1    Haft, C.R.2    Muys, L.3    Heinrich, P.C.4    Graeve, L.5
  • 14
    • 0034161391 scopus 로고    scopus 로고
    • Activation of Akt kinase by granulocyte colony-stimulating factor (G-CSF): Evidence for the role of a tyrosine kinase activity distinct from the Janus kinases
    • Dong F, Larner AC (2000) Activation of Akt kinase by granulocyte colony-stimulating factor (G-CSF): evidence for the role of a tyrosine kinase activity distinct from the Janus kinases. Blood 95: 1656-1662
    • (2000) Blood , vol.95 , pp. 1656-1662
    • Dong, F.1    Larner, A.C.2
  • 15
    • 15444366416 scopus 로고    scopus 로고
    • Feedback inhibition of leptin receptor/Jak2 signaling via Tyr1138 of the leptin receptor and suppressor of cytokine signaling 3
    • Dunn SL, Bjornholm M, Bates SH, Chen Z, Seifert M, Myers Jr MG (2005) Feedback inhibition of leptin receptor/Jak2 signaling via Tyr1138 of the leptin receptor and suppressor of cytokine signaling 3. Mol Endocrinol 19: 925-938
    • (2005) Mol Endocrinol , vol.19 , pp. 925-938
    • Dunn, S.L.1    Bjornholm, M.2    Bates, S.H.3    Chen, Z.4    Seifert, M.5    Myers Jr, M.G.6
  • 16
    • 34247194402 scopus 로고    scopus 로고
    • Novel role of WD40 and SOCS box protein-2 in steady-state distribution of granulocyte colony-stimulating factor receptor and G-CSF-controlled proliferation and differentiation signaling
    • Sept. 25, E-pub ahead of print
    • Erkeland SJ, Aarts LH, Irandoust M, Roovers O, Klomp A, Valkhof M, Gits J, Eyckerman S, Tavernier J, Touw IP (2006) Novel role of WD40 and SOCS box protein-2 in steady-state distribution of granulocyte colony-stimulating factor receptor and G-CSF-controlled proliferation and differentiation signaling. Oncogene 2006, Sept. 25, [E-pub ahead of print]
    • (2006) Oncogene
    • Erkeland, S.J.1    Aarts, L.H.2    Irandoust, M.3    Roovers, O.4    Klomp, A.5    Valkhof, M.6    Gits, J.7    Eyckerman, S.8    Tavernier, J.9    Touw, I.P.10
  • 17
    • 0037307086 scopus 로고    scopus 로고
    • The gene encoding the transcriptional regulator Yin Yang 1 (YY1) is a myeloid transforming gene interfering with neutrophilic differentiation
    • Erkeland SJ, Valkhof M, Heijmans-Antonissen C, Delwel R, Valk PJ, Hermans MH, Touw IP (2003) The gene encoding the transcriptional regulator Yin Yang 1 (YY1) is a myeloid transforming gene interfering with neutrophilic differentiation. Blood 101: 1111-1117
    • (2003) Blood , vol.101 , pp. 1111-1117
    • Erkeland, S.J.1    Valkhof, M.2    Heijmans-Antonissen, C.3    Delwel, R.4    Valk, P.J.5    Hermans, M.H.6    Touw, I.P.7
  • 18
    • 0033521670 scopus 로고    scopus 로고
    • Identification of a novel ubiquitin conjugation motif, required for ligand-induced internalization of the growth hormone receptor
    • Govers R, ten Broeke T, van Kerkhof P, Schwartz AL, Strous GJ (1999) Identification of a novel ubiquitin conjugation motif, required for ligand-induced internalization of the growth hormone receptor. EMBO J 18: 28-36
    • (1999) EMBO J , vol.18 , pp. 28-36
    • Govers, R.1    ten Broeke, T.2    van Kerkhof, P.3    Schwartz, A.L.4    Strous, G.J.5
  • 19
    • 0025287536 scopus 로고
    • Characterization and cloning of lgp110, a lysosomal membrane glycoprotein from mouse and rat cells
    • Granger BL, Green SA, Gabel CA, Howe CL, Mellman I, Helenius A (1990) Characterization and cloning of lgp110, a lysosomal membrane glycoprotein from mouse and rat cells. J Biol Chem 265: 12036-12043
    • (1990) J Biol Chem , vol.265 , pp. 12036-12043
    • Granger, B.L.1    Green, S.A.2    Gabel, C.A.3    Howe, C.L.4    Mellman, I.5    Helenius, A.6
  • 20
    • 1542373897 scopus 로고    scopus 로고
    • Distinct monoubiquitin signals in receptor endocytosis
    • Haglund K, Di Fiore PP, Dikic I (2003) Distinct monoubiquitin signals in receptor endocytosis. Trends Biochem Sci 28: 598-603
    • (2003) Trends Biochem Sci , vol.28 , pp. 598-603
    • Haglund, K.1    Di Fiore, P.P.2    Dikic, I.3
  • 22
    • 0038784346 scopus 로고    scopus 로고
    • Signaling mechanisms coupled to tyrosines in the granulocyte colony-stimulating factor receptor orchestrate G-CSF-induced expansion of myeloid progenitor cells
    • Hermans MH, van de Geijn GJ, Antonissen C, Gits J, van Leeuwen D, Ward AC, Touw IP (2003) Signaling mechanisms coupled to tyrosines in the granulocyte colony-stimulating factor receptor orchestrate G-CSF-induced expansion of myeloid progenitor cells. Blood 101: 2584-2590
    • (2003) Blood , vol.101 , pp. 2584-2590
    • Hermans, M.H.1    van de Geijn, G.J.2    Antonissen, C.3    Gits, J.4    van Leeuwen, D.5    Ward, A.C.6    Touw, I.P.7
  • 23
    • 0036681955 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction
    • Hortner M, Nielsch U, Mayr LM, Johnston JA, Heinrich PC, Haan S (2002) Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction. J Immunol 169: 1219-1227
    • (2002) J Immunol , vol.169 , pp. 1219-1227
    • Hortner, M.1    Nielsch, U.2    Mayr, L.M.3    Johnston, J.A.4    Heinrich, P.C.5    Haan, S.6
  • 24
    • 0033555810 scopus 로고    scopus 로고
    • Deletion of a critical internalization domain in the G-CSFR in acute myelogenous leukemia preceded by severe congenital neutropenia
    • Hunter MG, Avalos BR (1999) Deletion of a critical internalization domain in the G-CSFR in acute myelogenous leukemia preceded by severe congenital neutropenia. Blood 93: 440-446
    • (1999) Blood , vol.93 , pp. 440-446
    • Hunter, M.G.1    Avalos, B.R.2
  • 26
    • 0034775824 scopus 로고    scopus 로고
    • The suppressors of cytokine signalling (SOCS)
    • Kile BT, Alexander WS (2001) The suppressors of cytokine signalling (SOCS). Cell Mol Life Sci 58: 1627-1635
    • (2001) Cell Mol Life Sci , vol.58 , pp. 1627-1635
    • Kile, B.T.1    Alexander, W.S.2
  • 28
  • 29
    • 26644471035 scopus 로고    scopus 로고
    • Proteasomes mediate prolactin-induced receptor down-regulation and fragment generation in breast cancer cells
    • Lu JC, Piazza TM, Schuler LA (2005) Proteasomes mediate prolactin-induced receptor down-regulation and fragment generation in breast cancer cells. J Biol Chem 280: 33909-33916
    • (2005) J Biol Chem , vol.280 , pp. 33909-33916
    • Lu, J.C.1    Piazza, T.M.2    Schuler, L.A.3
  • 30
    • 1842591231 scopus 로고    scopus 로고
    • Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases
    • Marmor MD, Yarden Y (2004) Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases. Oncogene 23: 2057-2070
    • (2004) Oncogene , vol.23 , pp. 2057-2070
    • Marmor, M.D.1    Yarden, Y.2
  • 31
    • 3142592401 scopus 로고    scopus 로고
    • Not just a sink: Endosomes in control of signal transduction
    • Miaczynska M, Pelkmans L, Zerial M (2004) Not just a sink: endosomes in control of signal transduction. Curr Opin Cell Biol 16: 400-406
    • (2004) Curr Opin Cell Biol , vol.16 , pp. 400-406
    • Miaczynska, M.1    Pelkmans, L.2    Zerial, M.3
  • 33
    • 33644769212 scopus 로고    scopus 로고
    • Endocytosis conducts the cell signaling orchestra
    • Polo S, Di Fiore PP (2006) Endocytosis conducts the cell signaling orchestra. Cell 124: 897-900
    • (2006) Cell , vol.124 , pp. 897-900
    • Polo, S.1    Di Fiore, P.P.2
  • 35
    • 0031037912 scopus 로고    scopus 로고
    • Tyrosine 763 of the murine granulocyte colony-stimulating factor receptor mediates Ras-dependent activation of the JNK/SAPK mitogen-activated protein kinase pathway
    • Rausch O, Marshall CJ (1997) Tyrosine 763 of the murine granulocyte colony-stimulating factor receptor mediates Ras-dependent activation of the JNK/SAPK mitogen-activated protein kinase pathway. Mol Cell Biol 17: 1170-1179
    • (1997) Mol Cell Biol , vol.17 , pp. 1170-1179
    • Rausch, O.1    Marshall, C.J.2
  • 36
    • 1842424803 scopus 로고    scopus 로고
    • Protein tyrosine phosphatase-1B dephosphorylation of the insulin receptor occurs in a perinuclear endosome compartment in human embryonic kidney 293 cells
    • Romsicki Y, Reece M, Gauthier JY, Asante-Appiah E, Kennedy BP (2004) Protein tyrosine phosphatase-1B dephosphorylation of the insulin receptor occurs in a perinuclear endosome compartment in human embryonic kidney 293 cells. J Biol Chem 279: 12868-12875
    • (2004) J Biol Chem , vol.279 , pp. 12868-12875
    • Romsicki, Y.1    Reece, M.2    Gauthier, J.Y.3    Asante-Appiah, E.4    Kennedy, B.P.5
  • 37
    • 22844438893 scopus 로고    scopus 로고
    • Janus kinases affect thrombopoietin receptor cell surface localization and stability
    • Royer Y, Staerk J, Costuleanu M, Courtoy PJ, Constantinescu SN (2005) Janus kinases affect thrombopoietin receptor cell surface localization and stability. J Biol Chem 280: 27251-27261
    • (2005) J Biol Chem , vol.280 , pp. 27251-27261
    • Royer, Y.1    Staerk, J.2    Costuleanu, M.3    Courtoy, P.J.4    Constantinescu, S.N.5
  • 38
    • 33644550632 scopus 로고    scopus 로고
    • Unique structural determinants for Stat3 recruitment and activation by the granulocyte colony-stimulating factor receptor at phosphotyrosine ligands 704 and 744
    • Shao H, Xu X, Jing N, Tweardy DJ (2006) Unique structural determinants for Stat3 recruitment and activation by the granulocyte colony-stimulating factor receptor at phosphotyrosine ligands 704 and 744. J Immunol 176: 2933-2941
    • (2006) J Immunol , vol.176 , pp. 2933-2941
    • Shao, H.1    Xu, X.2    Jing, N.3    Tweardy, D.J.4
  • 40
    • 0033008075 scopus 로고    scopus 로고
    • Functional properties of leptin receptor isoforms: Internalization and degradation of leptin and ligand-induced receptor downregulation
    • Uotani S, Bjorbaek C, Tornoe J, Flier JS (1999) Functional properties of leptin receptor isoforms: internalization and degradation of leptin and ligand-induced receptor downregulation. Diabetes 48: 279-286
    • (1999) Diabetes , vol.48 , pp. 279-286
    • Uotani, S.1    Bjorbaek, C.2    Tornoe, J.3    Flier, J.S.4
  • 41
    • 1542388186 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor and its receptor in normal hematopoietic cell development and myeloid disease
    • van de Geijn GJ, Aarts LH, Erkeland SJ, Prasher JM, Touw IP (2003) Granulocyte colony-stimulating factor and its receptor in normal hematopoietic cell development and myeloid disease. Rev Physiol Biochem Pharmacol 149: 53-71
    • (2003) Rev Physiol Biochem Pharmacol , vol.149 , pp. 53-71
    • van de Geijn, G.J.1    Aarts, L.H.2    Erkeland, S.J.3    Prasher, J.M.4    Touw, I.P.5
  • 42
    • 3042696495 scopus 로고    scopus 로고
    • Distinct activities of suppressor of cytokine signaling (SOCS) proteins and involvement of the SOCS box in controlling G-CSF signaling
    • van de Geijn GJ, Gits J, Touw IP (2004b) Distinct activities of suppressor of cytokine signaling (SOCS) proteins and involvement of the SOCS box in controlling G-CSF signaling. J Leukoc Biol 76: 237-244
    • (2004) J Leukoc Biol , vol.76 , pp. 237-244
    • van de Geijn, G.J.1    Gits, J.2    Touw, I.P.3
  • 43
    • 3042741019 scopus 로고    scopus 로고
    • G-CSF receptor truncations found in SCN/AML relieve SOCS3-controlled inhibition of STAT5 but leave suppression of STAT3 intact
    • van de Geijn GJ, Gits J, Aarts LH, Heijmans-Antonissen C, Touw IP (2004a) G-CSF receptor truncations found in SCN/AML relieve SOCS3-controlled inhibition of STAT5 but leave suppression of STAT3 intact. Blood 104: 667-674
    • (2004) Blood , vol.104 , pp. 667-674
    • van de Geijn, G.J.1    Gits, J.2    Aarts, L.H.3    Heijmans-Antonissen, C.4    Touw, I.P.5
  • 44
    • 0034864712 scopus 로고    scopus 로고
    • The ubiquitin-proteasome pathway regulates lysosomal degradation of the growth hormone receptor and its ligand
    • van Kerkhof P, Strous GJ (2001) The ubiquitin-proteasome pathway regulates lysosomal degradation of the growth hormone receptor and its ligand. Biochem Soc Trans 29: 488-493
    • (2001) Biochem Soc Trans , vol.29 , pp. 488-493
    • van Kerkhof, P.1    Strous, G.J.2
  • 45
    • 0032938723 scopus 로고    scopus 로고
    • Tyrosine-dependent and -independent mechanisms of STAT3 activation by the human granulocyte colony-stimulating factor (G-CSF) receptor are differentially utilized depending on G-CSF concentration
    • Ward AC, Hermans MH, Smith L, van Aesch YM, Schelen AM, Antonissen C, Touw IP (1999a) Tyrosine-dependent and -independent mechanisms of STAT3 activation by the human granulocyte colony-stimulating factor (G-CSF) receptor are differentially utilized depending on G-CSF concentration. Blood 93: 113-124
    • (1999) Blood , vol.93 , pp. 113-124
    • Ward, A.C.1    Hermans, M.H.2    Smith, L.3    van Aesch, Y.M.4    Schelen, A.M.5    Antonissen, C.6    Touw, I.P.7
  • 46
    • 0033591347 scopus 로고    scopus 로고
    • Multiple signals mediate proliferation, differentiation, and survival from the granulocyte colony-stimulating factor receptor in myeloid 32D cells
    • Ward AC, Smith L, de Koning JP, van Aesch Y, Touw IP (1999b) Multiple signals mediate proliferation, differentiation, and survival from the granulocyte colony-stimulating factor receptor in myeloid 32D cells. J Biol Chem 274: 14956-14962
    • (1999) J Biol Chem , vol.274 , pp. 14956-14962
    • Ward, A.C.1    Smith, L.2    de Koning, J.P.3    van Aesch, Y.4    Touw, I.P.5
  • 47
    • 0033555439 scopus 로고    scopus 로고
    • Defective internalization and sustained activation of truncated granulocyte colony-stimulating factor receptor found in severe congenital neutropenia/acute myeloid leukemia
    • Ward AC, van Aesch YM, Schelen AM, Touw IP (1999c) Defective internalization and sustained activation of truncated granulocyte colony-stimulating factor receptor found in severe congenital neutropenia/acute myeloid leukemia. Blood 93: 447-458
    • (1999) Blood , vol.93 , pp. 447-458
    • Ward, A.C.1    van Aesch, Y.M.2    Schelen, A.M.3    Touw, I.P.4
  • 48
    • 0034548716 scopus 로고    scopus 로고
    • Involvement of the ubiquitin-proteasome pathway in the degradation of nontyrosine kinase-type cytokine receptors of IL-9, IL-2, and erythropoietin
    • Yen CH, Yang YC, Ruscetti SK, Kirken RA, Dai RM, Li CC (2000) Involvement of the ubiquitin-proteasome pathway in the degradation of nontyrosine kinase-type cytokine receptors of IL-9, IL-2, and erythropoietin. J Immunol 165: 6372-6380
    • (2000) J Immunol , vol.165 , pp. 6372-6380
    • Yen, C.H.1    Yang, Y.C.2    Ruscetti, S.K.3    Kirken, R.A.4    Dai, R.M.5    Li, C.C.6
  • 49
    • 25644444568 scopus 로고    scopus 로고
    • Tyrosine 729 of the G-CSF receptor controls the duration of receptor signaling: Involvement of SOCS3 and SOCS1
    • Zhuang D, Qiu Y, Haque SJ, Dong F (2005) Tyrosine 729 of the G-CSF receptor controls the duration of receptor signaling: involvement of SOCS3 and SOCS1. J Leukoc Biol 78: 1008-1015
    • (2005) J Leukoc Biol , vol.78 , pp. 1008-1015
    • Zhuang, D.1    Qiu, Y.2    Haque, S.J.3    Dong, F.4


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