-
1
-
-
0028101326
-
Rapid activation of the STAT3 transcription factor by granulocyte colony-stimulating factor
-
Tian, S. S., P. Lamb, H. M. Seidel, R. B. Stein, and J. Rosen. 1994. Rapid activation of the STAT3 transcription factor by granulocyte colony-stimulating factor. Blood 84: 1760-1764.
-
(1994)
Blood
, vol.84
, pp. 1760-1764
-
-
Tian, S.S.1
Lamb, P.2
Seidel, H.M.3
Stein, R.B.4
Rosen, J.5
-
2
-
-
0028806173
-
Granulocyte colony-stimulating factor rapidly activates a distinct STAT-like protein in normal myeloid cells
-
Tweardy, D. J., T. M. Wright, S. F. Ziegler, H. Baumann, A. Chakraborty, S. M. White, K. F. Dyer, and K. A. Rubin. 1995. Granulocyte colony-stimulating factor rapidly activates a distinct STAT-like protein in normal myeloid cells. Blood 86: 4409-4416.
-
(1995)
Blood
, vol.86
, pp. 4409-4416
-
-
Tweardy, D.J.1
Wright, T.M.2
Ziegler, S.F.3
Baumann, H.4
Chakraborty, A.5
White, S.M.6
Dyer, K.F.7
Rubin, K.A.8
-
3
-
-
0029796380
-
Granulocyte colony-stimulating factor activation of Stat3α and Stat3β in immature normal and leukemic human myeloid cells
-
Chakraborty, A., S. M. White, T. S. Schaefer, E. D. Ball, K. F. Dyer, and D. J. Tweardy. 1996. Granulocyte colony-stimulating factor activation of Stat3α and Stat3β in immature normal and leukemic human myeloid cells. Blood 88: 2442-2449.
-
(1996)
Blood
, vol.88
, pp. 2442-2449
-
-
Chakraborty, A.1
White, S.M.2
Schaefer, T.S.3
Ball, E.D.4
Dyer, K.F.5
Tweardy, D.J.6
-
4
-
-
0030851722
-
Involvement of STAT3 in the granulocyte colony-stimulating factor-induced differentiation of myeloid cells
-
Shimozaki, K., K. Nakajima, T. Hirano, and S. Nagata. 1997. Involvement of STAT3 in the granulocyte colony-stimulating factor-induced differentiation of myeloid cells. J. Biol. Chem. 272: 25184-25189.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 25184-25189
-
-
Shimozaki, K.1
Nakajima, K.2
Hirano, T.3
Nagata, S.4
-
5
-
-
0031825333
-
Stat3 and G-CSF-induced myeloid differentiation
-
Chakraborty, A., and D. J. Tweardy. 1998. Stat3 and G-CSF-induced myeloid differentiation. Leuk. Lymphoma 30: 433-442.
-
(1998)
Leuk. Lymphoma
, vol.30
, pp. 433-442
-
-
Chakraborty, A.1
Tweardy, D.J.2
-
6
-
-
0033591347
-
Multiple signals mediate proliferation, differentiation, and survival from the granulocyte colony-stimulating factor receptor in myeloid 32D cells
-
Ward, A. C., L. Smith, J. P. de Koning, Y. van Aesch, and I. P. Touw. 1999. Multiple signals mediate proliferation, differentiation, and survival from the granulocyte colony-stimulating factor receptor in myeloid 32D cells. J. Biol. Chem. 274: 14956-14962.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 14956-14962
-
-
Ward, A.C.1
Smith, L.2
De Koning, J.P.3
Van Aesch, Y.4
Touw, I.P.5
-
7
-
-
0034612529
-
Kip1
-
Kip1. Oncogene 19: 3290-3298.
-
(2000)
Oncogene
, vol.19
, pp. 3290-3298
-
-
De Koning, J.P.1
Soede-Bobok, A.A.2
Ward, A.C.3
Schelen, A.M.4
Antonissen, C.5
Van Leeuwen, D.6
Lowenberg, B.7
Touw, I.P.8
-
8
-
-
0035102228
-
STAT-3 activation is required for normal G-CSF-dependent proliferation and granulocytic differentiation
-
McLemore, M. L., S. Grewal, F. Liu, A. Archambault, J. Poursine-Laurent. J. Haug, and D. C. Link. 2001. STAT-3 activation is required for normal G-CSF-dependent proliferation and granulocytic differentiation. Immunity 14: 193-204.
-
(2001)
Immunity
, vol.14
, pp. 193-204
-
-
McLemore, M.L.1
Grewal, S.2
Liu, F.3
Archambault, A.4
Poursine-Laurent, J.5
Haug, J.6
Link, D.C.7
-
9
-
-
1442356947
-
G-CSF signaling can differentiate promyelocytes expressing a defective retinoic acid receptor: Evidence for divergent pathways regulating neutrophil differentiation
-
Maun, N. A., P. Gaines, A. Khanna-Gupta, T. Zibello, L. Enriquez, L. Goldberg, and N. Berliner. 2004. G-CSF signaling can differentiate promyelocytes expressing a defective retinoic acid receptor: evidence for divergent pathways regulating neutrophil differentiation. Blood 103: 1693-1701.
-
(2004)
Blood
, vol.103
, pp. 1693-1701
-
-
Maun, N.A.1
Gaines, P.2
Khanna-Gupta, A.3
Zibello, T.4
Enriquez, L.5
Goldberg, L.6
Berliner, N.7
-
10
-
-
3242683662
-
Single cell profiling of potentiated phospho-protein networks in cancer cells
-
Irish, J. M., R. Hovland, P. O. Krutzik, O. D. Perez, O. Bruserud, B. T. Gjertsen, and G. P. Nolan. 2004. Single cell profiling of potentiated phospho-protein networks in cancer cells. Cell 118: 217-228.
-
(2004)
Cell
, vol.118
, pp. 217-228
-
-
Irish, J.M.1
Hovland, R.2
Krutzik, P.O.3
Perez, O.D.4
Bruserud, O.5
Gjertsen, B.T.6
Nolan, G.P.7
-
11
-
-
0028964465
-
Cytokine signaling through nonreceptor protein tyrosine kinases
-
Taniguchi, T. 1995. Cytokine signaling through nonreceptor protein tyrosine kinases. Science 268: 251-255.
-
(1995)
Science
, vol.268
, pp. 251-255
-
-
Taniguchi, T.1
-
12
-
-
0028344499
-
Tyrosine kinase JAK1 is associated with the granulocyte-colony- stimulating factor receptor and both become tyrosine-phosphorylated after receptor activation
-
Nicholson, S. E., A. C. Oates, A. G. Harpur, A. Ziemiecki, A. F. Wilks, and J. E. Layton. 1994. Tyrosine kinase JAK1 is associated with the granulocyte-colony-stimulating factor receptor and both become tyrosine-phosphorylated after receptor activation. Proc. Natl. Acad. Sci. USA 91: 2985-2988.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 2985-2988
-
-
Nicholson, S.E.1
Oates, A.C.2
Harpur, A.G.3
Ziemiecki, A.4
Wilks, A.F.5
Layton, J.E.6
-
13
-
-
0027965247
-
G-CSF induces tyrosine phosphorylation of the JAK2 protein in the human myeloid G-CSF responsive and proliferative cells, but not in mature neutrophils
-
Shimoda, K., H. Iwasaki, S. Okamura, Y. Ohno, A. Kubota, F. Arima, T. Otsuka, and Y. Niho. 1994. G-CSF induces tyrosine phosphorylation of the JAK2 protein in the human myeloid G-CSF responsive and proliferative cells, but not in mature neutrophils. Biochem. Biophys. Res. Commun. 203: 922-928.
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.203
, pp. 922-928
-
-
Shimoda, K.1
Iwasaki, H.2
Okamura, S.3
Ohno, Y.4
Kubota, A.5
Arima, F.6
Otsuka, T.7
Niho, Y.8
-
14
-
-
0028788485
-
District regions of the granulocyte colony-stimulating factor receptor are required for tyrosine phosphorylation of the signaling molecules JAK2, Stat3, and p42, p44MAPK
-
Nicholson, S. E., U. Novak, S. F. Ziegler, and J. E. Layton. 1995. District regions of the granulocyte colony-stimulating factor receptor are required for tyrosine phosphorylation of the signaling molecules JAK2, Stat3, and p42, p44MAPK. Blood 86: 3698-3704.
-
(1995)
Blood
, vol.86
, pp. 3698-3704
-
-
Nicholson, S.E.1
Novak, U.2
Ziegler, S.F.3
Layton, J.E.4
-
15
-
-
0030068525
-
Specific involvement of tyrosine 764 of human granulocyte colony-stimulating factor receptor in signal transduction mediated by p145/Shc/GRB2 or p90/GRB2 complexes
-
de Koning, J. P., A. M. Schelen, F. Dong, C. van Buitenen, B. M. Burgering, J. L. Bos, B. Lowenberg, and I. P. Touw. 1996. Specific involvement of tyrosine 764 of human granulocyte colony-stimulating factor receptor in signal transduction mediated by p145/Shc/GRB2 or p90/GRB2 complexes. Blood 87: 132-140.
-
(1996)
Blood
, vol.87
, pp. 132-140
-
-
De Koning, J.P.1
Schelen, A.M.2
Dong, F.3
Van Buitenen, C.4
Burgering, B.M.5
Bos, J.L.6
Lowenberg, B.7
Touw, I.P.8
-
16
-
-
0346422462
-
Contribution of the membrane-distal tyrosine in intracellular signaling by the granulocyte colony-stimulating factor receptor
-
Kendrick, T. S., R. J. Lipscombe, O. Rausch, S. E. Nicholson, J. E. Layton, L. C. Goldie-Cregan, and M. A. Bogoyevitch. 2004. Contribution of the membrane-distal tyrosine in intracellular signaling by the granulocyte colony-stimulating factor receptor. J. Biol. Chem. 279: 326-340.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 326-340
-
-
Kendrick, T.S.1
Lipscombe, R.J.2
Rausch, O.3
Nicholson, S.E.4
Layton, J.E.5
Goldie-Cregan, L.C.6
Bogoyevitch, M.A.7
-
17
-
-
0032524993
-
Phosphatidylinositol 3′-kinase and SH2-containing inositol phosphatase (SHIP) are recruited by distinct positive and negative growth-regulatory domains in the granulocyte colony-stimulating factor receptor
-
Hunter, M. G., and B. R. Avalos. 1998. Phosphatidylinositol 3′-kinase and SH2-containing inositol phosphatase (SHIP) are recruited by distinct positive and negative growth-regulatory domains in the granulocyte colony-stimulating factor receptor. J. Immunol 160: 4979-4987.
-
(1998)
J. Immunol.
, vol.160
, pp. 4979-4987
-
-
Hunter, M.G.1
Avalos, B.R.2
-
18
-
-
0036681955
-
Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction
-
Hortner, M., U. Nielsch, L. M. Mayr, J. A. Johnston, P. C. Heinrich, and S. Haan. 2002. Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction. J. Immunol. 169: 1219-1227.
-
(2002)
J. Immunol.
, vol.169
, pp. 1219-1227
-
-
Hortner, M.1
Nielsch, U.2
Mayr, L.M.3
Johnston, J.A.4
Heinrich, P.C.5
Haan, S.6
-
19
-
-
0032915401
-
Identification of a novel Stat3 recruitment and activation motif within the granulocyte colony-stimulating factor receptor
-
Chakraborty, A., K. F. Dyer, M. Cascio, T. A. Mietzner, and D. J. Tweardy. 1999. Identification of a novel Stat3 recruitment and activation motif within the granulocyte colony-stimulating factor receptor. Blood 93: 15-24.
-
(1999)
Blood
, vol.93
, pp. 15-24
-
-
Chakraborty, A.1
Dyer, K.F.2
Cascio, M.3
Mietzner, T.A.4
Tweardy, D.J.5
-
20
-
-
0033555439
-
Defective internalization and sustained activation of truncated granulocyte colony-stimulating factor receptor found in severe congenital neutropenia/acute myeloid leukemia
-
Ward, A. C., Y. M. van Aesch, A. M. Schelen, and I. P. Touw. 1999. Defective internalization and sustained activation of truncated granulocyte colony-stimulating factor receptor found in severe congenital neutropenia/acute myeloid leukemia. Blood 93: 447-458.
-
(1999)
Blood
, vol.93
, pp. 447-458
-
-
Ward, A.C.1
Van Aesch, Y.M.2
Schelen, A.M.3
Touw, I.P.4
-
21
-
-
0027403027
-
SH2 domains recognize specific phosphopeptide sequences
-
Songyang, Z., S. E. Shoelson, M. Chaudhuri G. Gish, T. Pawson, W. G. Haser. F. King, T. Roberts, S. Ratnofsky, R. J. Lechleider, et al. 1993. SH2 domains recognize specific phosphopeptide sequences. Cell 72: 767-778.
-
(1993)
Cell
, vol.72
, pp. 767-778
-
-
Songyang, Z.1
Shoelson, S.E.2
Chaudhuri, M.3
Gish, G.4
Pawson, T.5
Haser, W.G.6
King, F.7
Roberts, T.8
Ratnofsky, S.9
Lechleider, R.J.10
-
22
-
-
0028598744
-
Specificity in recognition of phosphopeptides by src-homology 2 domains
-
Cantley, L. C., and Z. Songyang. 1994. Specificity in recognition of phosphopeptides by src-homology 2 domains. J. Cell Sci. Suppl. 18: 121-126.
-
(1994)
J. Cell Sci. Suppl.
, vol.18
, pp. 121-126
-
-
Cantley, L.C.1
Songyang, Z.2
-
23
-
-
0028931604
-
Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors
-
Stahl, N., T. J. Farruggella, T. G. Boulton, Z. Zhong, J. E. Darnell, Jr., and G. D. Yancopoulos. 1995. Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors. Science 267: 1349-1353.
-
(1995)
Science
, vol.267
, pp. 1349-1353
-
-
Stahl, N.1
Farruggella, T.J.2
Boulton, T.G.3
Zhong, Z.4
Darnell Jr., J.E.5
Yancopoulos, G.D.6
-
24
-
-
0029981103
-
Stat3 recruitment by two distinct ligand-induced, tyrosine-phosphorylated docking sites in the interleukin-10 receptor intracellular domain
-
Weber-Nordt, R. M., J. K. Riley, A. C. Greenlund, K. W. Moore, J. E. Darnell, and R. D. Schreiber, 1996. Stat3 recruitment by two distinct ligand-induced, tyrosine-phosphorylated docking sites in the interleukin-10 receptor intracellular domain. J. Biol. Chem. 271: 27954-27961.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 27954-27961
-
-
Weber-Nordt, R.M.1
Riley, J.K.2
Greenlund, A.C.3
Moore, K.W.4
Darnell, J.E.5
Schreiber, R.D.6
-
25
-
-
15844398102
-
Structural basis for specificity of Grb2-SH2 revealed by a novel ligand binding mode
-
Rahuel, J., B. Gay, D. Erdmann, A. Strauss, C. Garcia-Echeverria, P. Furet, G. Caravatti, H. Fretz, J. Schoepfer, and M. G. Gratter. 1996. Structural basis for specificity of Grb2-SH2 revealed by a novel ligand binding mode. Nat. Struct. Biol. 3: 586-589.
-
(1996)
Nat. Struct. Biol.
, vol.3
, pp. 586-589
-
-
Rahuel, J.1
Gay, B.2
Erdmann, D.3
Strauss, A.4
Garcia-Echeverria, C.5
Furet, P.6
Caravatti, G.7
Fretz, H.8
Schoepfer, J.9
Gratter, M.G.10
-
26
-
-
0032499801
-
Three-dimensional structure of the Stat3β homodimer bound to DNA
-
Becker, S., B. Groner, and C. W. Muller. 1998. Three-dimensional structure of the Stat3β homodimer bound to DNA. Nature 394: 145-151.
-
(1998)
Nature
, vol.394
, pp. 145-151
-
-
Becker, S.1
Groner, B.2
Muller, C.W.3
-
27
-
-
0029991793
-
Differential activation of acute phase response factor/Stat3 and Stal1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. II. Src homology SH1 domains define the specificity of stat factor activation
-
Hemmann, U., C. Gerhartz, B. Heesel, J. Sasse, G. Kurapkat, J. Grotzinger, A. Wollmer, Z. Zhong, J. E. Darnell, Jr., L. Graeve, et al. 1996. Differential activation of acute phase response factor/Stat3 and Stal1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. II. Src homology SH1 domains define the specificity of stat factor activation. J. Biol. Chem. 271: 12999-13007.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 12999-13007
-
-
Hemmann, U.1
Gerhartz, C.2
Heesel, B.3
Sasse, J.4
Kurapkat, G.5
Grotzinger, J.6
Wollmer, A.7
Zhong, Z.8
Darnell Jr., J.E.9
Graeve, L.10
-
28
-
-
0029666298
-
STAT3β, a splice variant of transcription factor STAT3, is a dominant negative regulator of transcription
-
Caldenhoven, E., D. T. B. van Dijk, R. Solari, J. Armstrong, J. A. M. Raaijmakers, J. W. J. Lammers, L. Koenderman, and R. P. de Groot. 1996. STAT3β, a splice variant of transcription factor STAT3, is a dominant negative regulator of transcription. J. Biol. Chem. 271: 13221-13227.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 13221-13227
-
-
Caldenhoven, E.1
Van Dijk, D.T.B.2
Solari, R.3
Armstrong, J.4
Raaijmakers, J.A.M.5
Lammers, J.W.J.6
Koenderman, L.7
De Groot, R.P.8
-
29
-
-
0043175471
-
Identification and characterization of signal transducer and activator of transcription 3 recruitment sites within the epidermal growth factor receptor
-
Shao, H., H. Y. Cheng, R. G. Cook, and D. J. Tweardy. 2003. Identification and characterization of signal transducer and activator of transcription 3 recruitment sites within the epidermal growth factor receptor. Cancer Res. 63: 3923-3930.
-
(2003)
Cancer Res.
, vol.63
, pp. 3923-3930
-
-
Shao, H.1
Cheng, H.Y.2
Cook, R.G.3
Tweardy, D.J.4
-
30
-
-
0032401006
-
Binding specificity of a class II-restricted hepatitis B epitope by DR molecules from responder and nonresponder vaccine recipients
-
Schuenke, K. W., R. G. Cook, and R. R. Rich. 1998. Binding specificity of a class II-restricted hepatitis B epitope by DR molecules from responder and nonresponder vaccine recipients. Hum. Immunol. 59: 783-793.
-
(1998)
Hum. Immunol.
, vol.59
, pp. 783-793
-
-
Schuenke, K.W.1
Cook, R.G.2
Rich, R.R.3
-
32
-
-
0026316304
-
Alternative forms of the human G-CSF receptor function in growth signal transduction
-
Published erratum appears in 1992 New Biol. 4: 172
-
Ziegler, S. F.. T. Davis, J. A. Schneringer, T. L. Franklin, T. W. Tough, M. Teepe, A. Larsen, D. E. Williams, and C. A. Smith. 1991. Alternative forms of the human G-CSF receptor function in growth signal transduction. [Published erratum appears in 1992 New Biol. 4: 172.] New Biol. 3: 1242-1248.
-
(1991)
New Biol.
, vol.3
, pp. 1242-1248
-
-
Ziegler, S.F.1
Davis, T.2
Schneringer, J.A.3
Franklin, T.L.4
Tough, T.W.5
Teepe, M.6
Larsen, A.7
Williams, D.E.8
Smith, C.A.9
-
33
-
-
3042696495
-
Distinct activities of suppressor of cytokine signaling (SOCS) proteins and involvement of the SOCS box in controlling G-CSF signaling
-
van de Geijn, G. J., J. Gits, and I. P. Touw. 2004. Distinct activities of suppressor of cytokine signaling (SOCS) proteins and involvement of the SOCS box in controlling G-CSF signaling. J. Leukocyte Biol. 76: 237-244.
-
(2004)
J. Leukocyte Biol.
, vol.76
, pp. 237-244
-
-
Van De Geijn, G.J.1
Gits, J.2
Touw, I.P.3
-
34
-
-
0029861777
-
Tyrosine residues in the granulocyte colony-stimulating factor (G-CSF) receptor mediate G-CSF-induced differentiation of murine myeloid leukemic (Ml) cells
-
Nicholson, S. E., R. Starr, U. Novak, D. J. Hilton, and J. E. Layton. 1996. Tyrosine residues in the granulocyte colony-stimulating factor (G-CSF) receptor mediate G-CSF-induced differentiation of murine myeloid leukemic (Ml) cells. J. Biol. Chem. 271: 26947-26953.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 26947-26953
-
-
Nicholson, S.E.1
Starr, R.2
Novak, U.3
Hilton, D.J.4
Layton, J.E.5
-
35
-
-
2442618276
-
Structural requirements for signal transducer and activator of transcription 3 binding to phosphotyrosine ligands containing the YXXQ motif
-
Shao, H., X. Xu, M. A. Mastrangelo, N. Jing, R. G. Cook, G. B. Legge, and D. J. Tweardy. 2004. Structural requirements for signal transducer and activator of transcription 3 binding to phosphotyrosine ligands containing the YXXQ motif. J. Biol. Chem. 279: 18967-18973
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 18967-18973
-
-
Shao, H.1
Xu, X.2
Mastrangelo, M.A.3
Jing, N.4
Cook, R.G.5
Legge, G.B.6
Tweardy, D.J.7
-
36
-
-
0032546729
-
Structural basis for the high affinity of amino-aromatic SH2 phosphopeptide ligands
-
Rahuel, J., C. Garcia-Echeverria, P. Furet, A. Strauss, G. Caravatti, H. Fretz, J. Schoepfer, and B. Gay. 1998. Structural basis for the high affinity of amino-aromatic SH2 phosphopeptide ligands. J. Mol. Biol. 279: 1013-1022.
-
(1998)
J. Mol. Biol.
, vol.279
, pp. 1013-1022
-
-
Rahuel, J.1
Garcia-Echeverria, C.2
Furet, P.3
Strauss, A.4
Caravatti, G.5
Fretz, H.6
Schoepfer, J.7
Gay, B.8
-
37
-
-
0037880473
-
The only active mutant of thymidylate synthase D169, a residue far from the site of methyl transfer, demonstrates the exquisite nature of enzyme specificity
-
Birdsall, D. L., J. Finer-Moore, and R. M. Stroud. 2003. The only active mutant of thymidylate synthase D169, a residue far from the site of methyl transfer, demonstrates the exquisite nature of enzyme specificity. Protein Eng. 16: 229-240.
-
(2003)
Protein Eng.
, vol.16
, pp. 229-240
-
-
Birdsall, D.L.1
Finer-Moore, J.2
Stroud, R.M.3
-
38
-
-
0035977055
-
Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation
-
Turkson, J., D. Ryan, J. S. Kim, Y. Zhang, Z. Chen, E. Haura, A. Laudano, S. Sebti, A. D. Hamilton, and R. Jove. 2001. Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation. J. Biol. Chem. 276: 45443-45455.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 45443-45455
-
-
Turkson, J.1
Ryan, D.2
Kim, J.S.3
Zhang, Y.4
Chen, Z.5
Haura, E.6
Laudano, A.7
Sebti, S.8
Hamilton, A.D.9
Jove, R.10
-
39
-
-
0022977712
-
A noncatalytic domain conserved among cytoplasmic protein-tyrosine kinases modifies the kinase function and transforming activity of Fujinami sarcoma virus P130gag-fps
-
Sadowski, I., J. C. Stone, and T. Pawson. 1986. A noncatalytic domain conserved among cytoplasmic protein-tyrosine kinases modifies the kinase function and transforming activity of Fujinami sarcoma virus P130gag-fps. Mol. Cell. Biol. 6: 4396-4408.
-
(1986)
Mol. Cell. Biol.
, vol.6
, pp. 4396-4408
-
-
Sadowski, I.1
Stone, J.C.2
Pawson, T.3
-
40
-
-
0242551544
-
Sequence, structure and energetic determinants of phosphopeptide selectivity of SH2 domains
-
Sheinerman, F. B., B. Al-Lazikani, and B. Honig. 2003. Sequence, structure and energetic determinants of phosphopeptide selectivity of SH2 domains. J. Mol. Biol. 334: 823-841.
-
(2003)
J. Mol. Biol.
, vol.334
, pp. 823-841
-
-
Sheinerman, F.B.1
Al-Lazikani, B.2
Honig, B.3
-
41
-
-
0027409064
-
Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: Crystal structures of the complexed and peptide-free forms
-
Waksman, G., S. E. Shoelson, N. Pant, D. Cowbum, and J. Kuriyan. 1993. Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms. Cell 72: 779-790.
-
(1993)
Cell
, vol.72
, pp. 779-790
-
-
Waksman, G.1
Shoelson, S.E.2
Pant, N.3
Cowbum, D.4
Kuriyan, J.5
-
42
-
-
0037294154
-
Identification of a high-affinity phosphopeptide inhibitor of stat3
-
Ren, Z., L. A. Cabell, T. S. Schaefer, and J. S. McMurray. 2003. Identification of a high-affinity phosphopeptide inhibitor of stat3. Bioorg. Med. Chem. Lett. 13: 633-636.
-
(2003)
Bioorg. Med. Chem. Lett.
, vol.13
, pp. 633-636
-
-
Ren, Z.1
Cabell, L.A.2
Schaefer, T.S.3
McMurray, J.S.4
-
43
-
-
0037507282
-
Characterization of phosphopeptide motifs specific for the Src homology 2 domains of signal transducer and activator of transcription 1 (STAT1) and STAT3
-
Wiederkehr-Adam, M., P. Ernst, K. Muller, E. Bieck, F. O. Gombert, J. Ottl, P. Graff, F. Grossmuller, and M. H. Heim. 2003. Characterization of phosphopeptide motifs specific for the Src homology 2 domains of signal transducer and activator of transcription 1 (STAT1) and STAT3. J. Biol. Chem. 278: 16117-16128.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 16117-16128
-
-
Wiederkehr-Adam, M.1
Ernst, P.2
Muller, K.3
Bieck, E.4
Gombert, F.O.5
Ottl, J.6
Graff, P.7
Grossmuller, F.8
Heim, M.H.9
-
44
-
-
0033752859
-
β- and γ-turns in proteins revisited: A new set of amino acid turn-type dependent positional preferences and potentials
-
Guruprasad, K., and S. Rajkumar. 2000. β- and γ-turns in proteins revisited: a new set of amino acid turn-type dependent positional preferences and potentials. J. Biosci. 25: 143-156.
-
(2000)
J. Biosci.
, vol.25
, pp. 143-156
-
-
Guruprasad, K.1
Rajkumar, S.2
-
45
-
-
20144376462
-
Structural bases of unphosphorylated STAT1 association and receptor binding
-
Mao, X., Z. Ren, G. N. Parker, H. Sondermann, M. A. Pastorello, W. Wang, J. S. McMurray, B. Demeler, J. E. Darnell, Jr., and X. Chen. 2005. Structural bases of unphosphorylated STAT1 association and receptor binding. Mol. Cell 17:761-771.
-
(2005)
Mol. Cell
, vol.17
, pp. 761-771
-
-
Mao, X.1
Ren, Z.2
Parker, G.N.3
Sondermann, H.4
Pastorello, M.A.5
Wang, W.6
McMurray, J.S.7
Demeler, B.8
Darnell Jr., J.E.9
Chen, X.10
-
46
-
-
3142676436
-
Overriding imatinib resistance with a novel ABL kinase inhibitor
-
Shah, N. P., C. Tran, F. Y. Lee, P. Chen, D. Norris, and C. L. Sawyers. 2004. Overriding imatinib resistance with a novel ABL kinase inhibitor. Science 305: 399-401.
-
(2004)
Science
, vol.305
, pp. 399-401
-
-
Shah, N.P.1
Tran, C.2
Lee, F.Y.3
Chen, P.4
Norris, D.5
Sawyers, C.L.6
-
47
-
-
1642323740
-
Protein kinase inhibitors: Insights into drug design from structure
-
Noble, M. E., J. A. Endicott, and L. N. Johnson. 2004. Protein kinase inhibitors: insights into drug design from structure. Science 303: 1800-1805.
-
(2004)
Science
, vol.303
, pp. 1800-1805
-
-
Noble, M.E.1
Endicott, J.A.2
Johnson, L.N.3
-
48
-
-
0037534034
-
Potent Grb2-SH2 domain antagonists not relying on phosphotyrosine mimics
-
Li, P., M. Zhang, Y. Q. Long, M. L. Peach, H. Liu, D. Yang, M. Nicklaus, and P. P. Roller. 2003. Potent Grb2-SH2 domain antagonists not relying on phosphotyrosine mimics. Bioorg. Med. Chem. Lett. 13: 2173-2177.
-
(2003)
Bioorg. Med. Chem. Lett.
, vol.13
, pp. 2173-2177
-
-
Li, P.1
Zhang, M.2
Long, Y.Q.3
Peach, M.L.4
Liu, H.5
Yang, D.6
Nicklaus, M.7
Roller, P.P.8
-
49
-
-
17944368273
-
A novel phosphotyrosine mimetic 4′-carboxymethyloxy-3′- phosphonophenylalanine (Cpp): Exploitation in the design of nonpeptide inhibitors of pp60(Src) SH2 domain
-
Kawahata, N., M. G. Yang, G. P. Luke, W. C. Shakespeare, R. Sundaramoorthi, Y. Wang, D. Johnson, T. Merry, S. Violette, W. Guan, et al. 2001. A novel phosphotyrosine mimetic 4′-carboxymethyloxy-3′- phosphonophenylalanine (Cpp): exploitation in the design of nonpeptide inhibitors of pp60(Src) SH2 domain. Bioorg. Med. Chem. Lett. 11: 2319-2323.
-
(2001)
Bioorg. Med. Chem. Lett.
, vol.11
, pp. 2319-2323
-
-
Kawahata, N.1
Yang, M.G.2
Luke, G.P.3
Shakespeare, W.C.4
Sundaramoorthi, R.5
Wang, Y.6
Johnson, D.7
Merry, T.8
Violette, S.9
Guan, W.10
-
50
-
-
0036783394
-
SRC homology-2 inhibitors: Peptidomimetic and nonpeptide
-
Sawyer, T. K., R. S. Bohacek, D. C. Dalgarno, C. J. Eyermann, N. Kawahata, C. A. Metcalf, 3rd, W. C. Shakespeare, R. Sundaramoorthi, Y. Wang, and M. G. Yang. 2002. SRC homology-2 inhibitors: peptidomimetic and nonpeptide. Mini Rev. Med. Chem. 2: 475-488.
-
(2002)
Mini Rev. Med. Chem.
, vol.2
, pp. 475-488
-
-
Sawyer, T.K.1
Bohacek, R.S.2
Dalgarno, D.C.3
Eyermann, C.J.4
Kawahata, N.5
Metcalf III, C.A.6
Shakespeare, W.C.7
Sundaramoorthi, R.8
Wang, Y.9
Yang, M.G.10
-
52
-
-
0036093058
-
Constitutive activity of signal transducer and activator of transcription 3 protein in acute myeloid leukemia blasts is associated with short disease-free survival
-
Benekli, M., Z. Xia, K. A. Donohue, L. A. Ford, L. A. Pixley, M. R. Baer, H. Baumann, and M. Wetzler. 2002. Constitutive activity of signal transducer and activator of transcription 3 protein in acute myeloid leukemia blasts is associated with short disease-free survival. Blood 99: 252-257.
-
(2002)
Blood
, vol.99
, pp. 252-257
-
-
Benekli, M.1
Xia, Z.2
Donohue, K.A.3
Ford, L.A.4
Pixley, L.A.5
Baer, M.R.6
Baumann, H.7
Wetzler, M.8
-
53
-
-
0035136846
-
Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression
-
Epling-Burnette, P. K., J. H. Liu, R. Catlett-Falcone, J. Turkson, M. Oshiro. R. Kothapalli, Y. Li, J. M. Wang, H. F. Yang-Yen, J. Karras, et al. 2001. Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression. J. Clin. Invest. 107: 351-362.
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 351-362
-
-
Epling-Burnette, P.K.1
Liu, J.H.2
Catlett-Falcone, R.3
Turkson, J.4
Oshiro, M.5
Kothapalli, R.6
Li, Y.7
Wang, J.M.8
Yang-Yen, H.F.9
Karras, J.10
-
54
-
-
0032984589
-
Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells
-
Catlett-Falcone, R., T. H. Landowski, M. M. Oshiro, J. Turkson, A. Levitzki, R. Savino, G. Ciliberto, L. Moscinski, J. L. Fernandez-Luna, G. Nunez, et al. 1999. Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. Immunity 10: 105-115.
-
(1999)
Immunity
, vol.10
, pp. 105-115
-
-
Catlett-Falcone, R.1
Landowski, T.H.2
Oshiro, M.M.3
Turkson, J.4
Levitzki, A.5
Savino, R.6
Ciliberto, G.7
Moscinski, L.8
Fernandez-Luna, J.L.9
Nunez, G.10
-
55
-
-
0035799531
-
Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells
-
Garcia, R., T. L. Bowman, G. Niu, H. Yu, S. Minton, C. A. Muro-Cacho, C. E. Cos, R. Falcone, R. Fairclough, S. Parsons, et al. 2001. Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells. Oncogene 20: 2499-2513.
-
(2001)
Oncogene
, vol.20
, pp. 2499-2513
-
-
Garcia, R.1
Bowman, T.L.2
Niu, G.3
Yu, H.4
Minton, S.5
Muro-Cacho, C.A.6
Cos, C.E.7
Falcone, R.8
Fairclough, R.9
Parsons, S.10
-
56
-
-
4644325545
-
G-quartet oligonucleotides: A new class of signal transducer and activator of transcription 3 inhibitors that suppresses growth of prostate and breast tumors through induction of apoptosis
-
Jing, N., Y. Li, W. Xiong, W. Sha, L. Jing, and D. J. Tweardy. 2004. G-quartet oligonucleotides: a new class of signal transducer and activator of transcription 3 inhibitors that suppresses growth of prostate and breast tumors through induction of apoptosis. Cancer Res. 64: 6603-6609.
-
(2004)
Cancer Res.
, vol.64
, pp. 6603-6609
-
-
Jing, N.1
Li, Y.2
Xiong, W.3
Sha, W.4
Jing, L.5
Tweardy, D.J.6
-
57
-
-
0037112367
-
Constitutive activation of Stat3 in human prostate tumors and cell lines: Direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells
-
Mora, L. B., R. Buettner, J. Seigne, J. Diaz, N. Ahmad, R. Garcia, T. Bowman, R. Falcone, R. Fairclough, A. Cantor, et al. 2002. Constitutive activation of Stat3 in human prostate tumors and cell lines: direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells. Cancer Res. 62: 6659-6666.
-
(2002)
Cancer Res.
, vol.62
, pp. 6659-6666
-
-
Mora, L.B.1
Buettner, R.2
Seigne, J.3
Diaz, J.4
Ahmad, N.5
Garcia, R.6
Bowman, T.7
Falcone, R.8
Fairclough, R.9
Cantor, A.10
-
58
-
-
0013689209
-
Requirement of Stat3 but not Stall activation for epidermal growth factor receptor-mediated cell growth in vitro
-
Grandis, J. R., S. D. Drenning, A. Chakraborty, M. Y. Zhou, Q. Zeng, A. S. Pitt, and D. J. Tweardy. 1998. Requirement of Stat3 but not Stall activation for epidermal growth factor receptor-mediated cell growth In vitro. J. Clin. Invest. 102: 1385-1392.
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 1385-1392
-
-
Grandis, J.R.1
Drenning, S.D.2
Chakraborty, A.3
Zhou, M.Y.4
Zeng, Q.5
Pitt, A.S.6
Tweardy, D.J.7
-
59
-
-
12944272024
-
Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo
-
Grandis, J. R., S. D. Drenning, Q. Zeng, S. C. Watkins, M. F. Melhem, S. Endo, D. E. Johnson, L. Huang, Y. He, and J. D. Kim. 2000. Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo. Proc. Natl. Acad. Sci. USA 97: 4227-4232.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 4227-4232
-
-
Grandis, J.R.1
Drenning, S.D.2
Zeng, Q.3
Watkins, S.C.4
Melhem, M.F.5
Endo, S.6
Johnson, D.E.7
Huang, L.8
He, Y.9
Kim, J.D.10
-
60
-
-
0036338213
-
STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation
-
Lee, C. K., R. Raz, R. Gimeno, R. Gertner, B. Wistinghausen, K. Takeshita, R. A. DePinho, and D. E. Levy. 2002. STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation. Immunity 17; 63-72.
-
(2002)
Immunity
, vol.17
, pp. 63-72
-
-
Lee, C.K.1
Raz, R.2
Gimeno, R.3
Gertner, R.4
Wistinghausen, B.5
Takeshita, K.6
DePinho, R.A.7
Levy, D.E.8
|