Growth Hormone Receptor Ubiquitination, Endocytosis, and Degradation Are Independent of Signal Transduction via Janus Kinase 2

Journal of Biological Chemistry

Volumn 276, Issue 35, 2001, Pages 32635-32641

  Alves dos Santos, Cristina M ^a   Ten Broeke, Toine ^a   Strous, Ger J ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; DEGRADATION; ENZYMES; HORMONES;

HORMONE RECEPTORS; PHOSPHORYLATION;

BIOCHEMISTRY;

CYTOKINE RECEPTOR; GROWTH HORMONE RECEPTOR; JANUS KINASE; JANUS KINASE 2; PROTEASOME; PROTEIN TYROSINE KINASE; UBIQUITIN; UNCLASSIFIED DRUG; HUMAN GROWTH HORMONE; JAK2 PROTEIN, HUMAN; ONCOPROTEIN; PHOSPHOTYROSINE; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; DOWN REGULATION; ENDOCYTOSIS; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; INTERNALIZATION; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FAMILY; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; CHEMISTRY; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; HAMSTER; HUMAN; KINETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; RABBIT; SITE DIRECTED MUTAGENESIS; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALIA; JANUS;

ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; CRICETINAE; ENDOCYTOSIS; HUMAN GROWTH HORMONE; HUMANS; JANUS KINASE 2; KINETICS; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; RABBITS; RECEPTORS, SOMATOTROPIN; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TRANSFECTION; UBIQUITINS;

EID: 0035980108     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M103583200     Document Type: Article

References (36)

1. Kelly, P. A., Ali, S., Rozakis, M., Goujon, L., Nagano, M., Pellegrini, I., Gould, D., Djiane, J., Edery, M., Finidori, J., and Postel-Vinay, M. C. (1993) Recent Prog. Horm. Res. 48, 123-164
2. Finidori, J. (2000) Vitam. Horm. 59, 71-97
3. Carter-Su, C., and Smit, L. S. (1998) Recent Prog. Horm. Res. 53, 61-83
4. VanderKuur, J. A., Wang, X., Zhang, L., Cambell, G. S., Allevato, G., Billestrup, N., Norstedt, G., and Carter-Su, C. (1994) J. Biol. Chem. 269, 21709-21717
5. Frank, S. J., Gilliland, G., Kraft, A. S., and Arnold, C. S. (1994) Endocrinology 135, 2228-2239
6. Argetsinger, L. S., Campbell, G. S., Yang, X., Witthuhn, B. A., Silvennoinen, O., Ihle, J. N., and Carter-Su, C. (1993) Cell 74, 237-244
7. Sotiropoulos, A., Perrot-Applanat, M., Dinerstein, H., Pallier, A., Postel-Vinay, M. C., Finidori, J., and Kelly, P. A. (1994) Endocrinology 135, 1292-1298
8. Han, Y., Leaman, D. W., Watling, D., Rogers, N. C., Groner, B., Kerr, I. M., Wood, W. I., and Stark, G. R. (1996) J. Biol. Chem. 271, 5947-5952
9. Thirone, A. C., Carvalho, C. R. O., and Saad, M. J. A. (1999) Endocrinology 140, 55-62
10. Smit, L. S., Meyer, D. J., Billestrup, N., Norstedt, G., Schwartz, J., and Carter-Su, C. (1996) Mol. Endocrinol. 10, 519-533
11. Wang, Y.-D., and Wood, W. I. (1995) Mol. Endocrinol. 9, 303-311
12. Billestrup, N., Bouchelouche, P., Allevato, G., Ilondo, M., and Nielsen, J. H. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 2725-2729
13. Sotiropoulos, A., Moutoussamy, S., Renaudie, F., Clauss, M., Kayser, C., Gouilleux, F., Kelly, P. A., and Finidori, J. (1996) Mol. Endocrinol. 10, 998-1009
14. Goujon, L., Allevato, G., Simonin, G., Paquereau, L., Le Cam, A., Clark, J., Nielsen, J. H., Djiane, J., Postel-Vinay, M. C., Edery, M., and Kelly, P. A. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 957-961
15. Allevato, G., Billestrup, N., Goujon, L., Galsgaard, E. D., Norstedt, G., Postel-Vinay, M. C., Kelly, P. A., and Nielsen, J. H. (1995) J. Biol. Chem. 270, 17210-17214
16. Argetsinger, L. S., Norstedt, G., Billestrup, N., White, M. F., and Carter-Su, C. (1996) J. Biol. Chem. 271, 29415-29421
17. Roupas, P., and Herington, A. C. (1988) Mol. Cell. Endocrinol. 57, 93-99
18. Murphy, L. J., and Lazarus, L. (1984) Endocrinology 115, 1625-1632
19. Strous, G. J., van Kerkhof, P., Govers, R., Ciechanover, A., and Schwartz, A. L. (1996) EMBO J. 15, 3806-3812
20. Govers, R., van Kerkhof, P., Schwartz, A. L., and Strous, G. J. (1997) EMBO J. 16, 4851-4858
21. Govers, R., ten Broeke, T., van Kerkhof, P., Schwartz, A. L., and Strous, G. J. (1999) EMBO J. 18, 28-36
22. van Kerkhof, P., Govers, G., Alves dos Santos, C. M., and Strous, G. J. (2000) J. Biol. Chem. 275, 1575-1580
23. Lamaze, C., and Schmid, S. L. (1995) J. Cell Biol. 129, 47-54
24. Fergusan, S. S., Barak, L. S., Zhang, J., and Caron, M. G. (1996) Can. J. Physiol. Pharmacol. 74, 1095-1110
25. Freedman, N. J., and Lefkowitz, R. J. (1996) Recent Prog. Horm. Res. 51, 352-353
26. Chen, W. S., Lazar, C. S., Poenie, M., Tsien, R. Y., Gill, G. N., and Rosenfeld, M. G. (1987) Nature 328, 820-823
27. Honegger, A. M. Dull, T. J., Felder, S., Van Obberghen, E., Bellot, F., Szapary, D., Schmidt, A., Ullrich, A., and Schlessinger J. (1987) Cell 51, 199-209
28. Alves dos Santos, C., van Kerkhof, P., and Strous, G. J. (2001) J. Biol. Chem. 276, 10839-10846
29. Strous, G. J., van Kerkhof, P., Govers, R., Rotwein, P., and Schwartz, A. L. (1997) J. Biol. Chem. 272, 40-43
30. Colosi, P., Wong, K., Leong, S. R., and Wood, W. I. (1993) J. Biol. Chem. 268, 12617-12623
31. Moller, C., Hansson, A., Enberg, B., Lobie, P. E., and Norstedt, G. (1992) J. Biol. Chem. 267, 23403-23408
32. Moldrup, A., Billestrup, N., Dryberg, T., and Nielsen, J. H. (1991) J. Biol. Chem. 266, 17441-17445
33. Sorkin, A., Mazzotti, M., Sorkina, T., Scotto, L., and Beguinot, L. (1996) J. Biol. Chem. 271, 13377-13384
34. Wilde, A., Beattie, E. C., Lem, L., Riethof, D. A., Liu, S.-H., Mobley, W. C., Soriano, P., and Brodsky, F. M. (1999) Cell 96, 677-687
35. VanderKuur, J. A., Butch, E. R., Waters, S. B., Pessin, J. E., Guan, K. L., and Carter-Su, C.(1997) Endocrinology 138, 4301-4307
36. Beckman, D, Lin, L. L., Quinones, M. E., and Longmore, G. D. (1999) Blood 94, 2667-2675