Role of the histamine system in nefopam-induced antinociception in mice

European Journal of Pharmacology

Volumn 503, Issue 1-3, 2004, Pages 63-69

  Girard, Philippe ^a   Pansart, Yannick ^a   Coppé, Marie Claude ^a   Verniers, Danielle ^a   Gillardin, Jean Marie ^a  

^a Service de Pharmacologie   (France)

Author keywords

Formalin; Histamine; Nefopam; Nociception; Writhing

Indexed keywords

ACETIC ACID; ALPHA METHYLHISTAMINE; ANALGESIC AGENT; ANTIHISTAMINIC AGENT; CIMETIDINE; FORMALDEHYDE; HISTAMINE; HISTAMINE H1 RECEPTOR ANTAGONIST; HISTAMINE H2 RECEPTOR ANTAGONIST; HISTAMINE H3 RECEPTOR ANTAGONIST; MEPYRAMINE MALEATE; NEFOPAM; THIOPERAMIDE; ZOLANTIDINE;

ANALGESIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; DRUG SAFETY; MALE; MOUSE; NEUROMODULATION; NONHUMAN; PAIN ASSESSMENT; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN FUNCTION; RECEPTOR AFFINITY; RECEPTOR BLOCKING; WRITHING TEST;

ACETIC ACID; ANALGESICS, NON-NARCOTIC; ANIMALS; ENZYME INHIBITORS; FORMALDEHYDE; GUINEA PIGS; HISTAMINE; HISTAMINE AGONISTS; HISTAMINE ANTAGONISTS; HISTAMINE H1 ANTAGONISTS; HISTAMINE H2 ANTAGONISTS; MALE; METHYLHISTAMINES; METHYLHISTIDINES; MICE; MICE, INBRED ICR; NEFOPAM; PAIN MEASUREMENT; PYRILAMINE; RECEPTORS, HISTAMINE H1; RECEPTORS, HISTAMINE H2; RECEPTORS, HISTAMINE H3;

EID: 7444270344     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.09.030     Document Type: Article

References (47)

1. I. Alvarez, F. Andreu, J. Buxens, M. Colombo, A. Dordal, M. Fort, B. Gutierrez, and A.J. Farre Pharmacology of cizolirtine: a new analgesic agent Methods Find. Exp. Clin. Pharmacol. 22 2000 211 221
2. J.M. Arrang Pharmacological properties of histamine receptor subtypes Cell. Mol. Biol. (Noisy-le-grand) 40 1994 275 281
3. J.M. Arrang, M. Garbarg, J.C. Lancelot, J.M. Lecomte, H. Pollard, M. Robba, W. Schunack, and J.C. Schwartz Highly potent and selective ligands for histamine H3-receptors Nature 327 1987 117 123
4. W.T. Beaver, and G.A. Feise A comparison of the analgesic effect of intramuscular nefopam and morphine in patients with post-operative pain J. Clin. Pharmacol. 17 1977 579 591
5. E.A. Brown, R. Griffiths, C.A. Harvey, and D.A. Owen Pharmacological studies with SK and F 93944 (temelastine), a novel histamine H1-receptor antagonist with negligible ability to penetrate the central nervous system Br. J. Pharmacol. 87 1986 569 578
6. R.E. Brown, D.R. Stevens, and H.L. Hass The physiology of brain histamine Prog. Neurobiol. 63 2001 637 672
7. J. Buritova, and J.M. Besson Effects of nefopam on the spinal nociceptive processes: a c-fos protein study in the rat Eur. J. Pharmacol. 441 2002 67 74
8. C.R. Calcutt, C.R. Ganellin, R. Griffiths, B.K. Leigh, J.P. Maguire, R.C. Mitchell, M.E. Mylek, M.E. Parsons, I.R. Smith, and R.C. Young Zolantidine (SK and F 95282) is a potent selective brain-penetrating histamine H2-receptor antagonist Br. J. Pharmacol. 93 1988 69 78
9. J. Clapham, and G.J. Kilpatrick Histamine H3 receptors modulate the release of [3H]-acetylcholine from slices of rat entorhinal cortex: evidence for the possible existence of H3 receptor subtypes Br. J. Pharmacol. 107 1992 919 923
10. A.C. Conway, and C.L. Mitchell Analgesic studies with nefopam hydrochloride Arch. Int. Pharmacodyn. Ther. 226 1977 156 171
11. D. Farzin, L. Asghari, and M. Nowrouzi Rodent antinociception following acute treatment with different histamine receptor agonists and antagonists Pharmacol. Biochem. Behav. 72 2002 751 760
12. O.B. Fasmer, O.G. Berge, H.A. Jorgensen, and K. Hole Antinociceptive effects of (±)-, (+)- and (-)-nefopam in mice J. Pharm. Pharmacol. 39 1987 508 511
13. R.W. Fuller, and H.D. Snoddy Evaluation of nefopam as a monoamine uptake inhibitor in vivo in mice Neuropharmacology 32 1993 995 999
14. M. Garbarg, G. Barbin, E. Rodergas, and J.C. Schwartz Inhibition of histamine synthesis in brain by alpha-fluoromethylhistidine, a new irreversible inhibitor: in vitro and in vivo studies J. Neurochem. 35 1980 1045 1052
15. M. Garbarg, M.D. Trung Tuong, C. Gros, and J.C. Schwartz Effect of histamine H3-receptor ligands on various biochemical indices of histaminergic neuron activity in rat brain Eur. J. Pharmacol. 164 1989 1 11
16. C. Ghelardini, N. Galeotti, and A. Bartolini No development of tolerance to analgesia by repeated administration of H-1 antagonists Life Sci. 63 1998 PL 317 PL 322
17. P. Girard, Y. Pansart, M.C. Coppe, and J.M. Gillardin Nefopam reduces thermal hypersensitivity in acute and postoperative pain models in the rat Pharmacol. Res. 44 2001 541 545
18. R.C. Heel, R.N. Brogden, G.E. Pakes, T.M. Speight, and G.S. Avery Nefopam: a review of its pharmacological properties and therapeutic efficacy Drugs 19 1980 249 267
19. L.B. Hough, S.D. Glick, and K. Su Cimetidine penetrates brain and inhibits non-opiate footshock-induced analgesia Pharmacol. Biochem. Behav. 24 1986 1257 1261
20. S. Hunskaar, O.B. Fasmer, and K. Hole Formalin test in mice, a useful technique for evaluating mild analgesics J. Neurosci. Methods 14 1985 69 76
21. S. Hunskaar, and K. Hole The formalin test in mice: dissociation between inflammatory and non-inflammatory pain Pain 30 1987 103 114
22. R. Karlsten, T. Gordh, and C. Post Local antinociceptive and hyperalgesic effects in the formalin test after peripheral administration of adenosine analogues in mice Pharmacol. Toxicol. 70 1992 434 438
23. M.W. Klohs, M.D. Draper, F.J. Petracek, and K.H. Ginzel Benzoxacines: a new chemical class of centrally acting skeletal muscle relaxants Arzneimittel-Forschung 22 1972 132 133
24. C. Lamberti, A. Bartolini, C. Ghelardini, and P. Malmberg-Aiello Investigation into the role of histamine receptors in rodent antinociception Pharmacol. Biochem. Behav. 53 1996 567 574
25. B.Y. Li, J.W. Nalwalk, and L.B. Hough Effects of naltrexone and histamine antagonists on the antinociceptive activity of the cimetidine analog SKF92374 in rats Brain Res. 748 1997 168 174
26. J.T. Litchfield, and F. Wilcoxon A simple method for evaluating dose-effect experiments J. Pharmacol. Exp. Ther. 96 1949 99 113
27. K. Maeyama, T. Watanabe, Y. Taguchi, A. Yamatodani, and H. Wada Effect of alpha-fluoromethylhistidine, a suicide inhibitor of histidine decarboxylase, on histamine levels in mouse tissues Biochem. Pharmacol. 31 1982 2367 2370
28. P. Malmberg-Aiello, C. Lamberti, C. Ghelardini, A. Giotti, and A. Bartolini Role of histamine in rodent antinociception Br. J. Pharmacol. 111 1994 1269 1279
29. P. Malmberg-Aiello, C. Lamberti, A. Ipponi, A. Bartolini, and W. Schunack Evidence for hypernociception induction following histamine H1 receptor activation in rodents Life Sci. 63 1998 463 476
30. M.J. Millan, L. Seguin, P. Honore, S. Girardon, and K. Bervoets Pro- and antinociceptive actions of serotonin (5-HT)1A agonists and antagonists in rodents: relationship to algesiometric paradigm Behav. Brain Res. 73 1996 69 77
31. J.I. Mobarakeh, S. Sakurada, S. Katsuyama, M. Kutsuwa, A. Kuramasu, Z.Y. Lin, T. Watanabe, Y. Hashimoto, T. Watanabe, and K. Yanai Role of histamine H-1 receptor in pain perception: a study of the receptor gene knockout mice Eur. J. Pharmacol. 391 2000 81 89
32. P.C. Moser The effect of 5-HT3 receptor antagonists on the writhing response in mice Gen. Pharmacol. 26 1995 1301 1306
33. R. Oishi, Y. Itoh, M. Nishibori, and K. Saeki Effects of the histamine H3-agonist (R)-alpha-methylhistamine and the antagonist thioperamide on histamine metabolism in the mouse and rat brain J. Neurochem. 52 1989 1388 1392
34. A.O. Oluyomi, and S.L. Hart Involvement of histamine in naloxone-resistant and naloxone-sensitive models of swim stress-induced antinociception in the mouse Neuropharmacology 30 1991 1021 1027
35. M.J. Ormazabal, C. Goicoechea, M.J. Alfaro, E. Sanchez, and M.I. Martin Study of mechanisms of calcitonin analgesia in mice. Involvement of 5-HT3 receptors Brain Res. 845 1999 130 138
36. M.F. Piercey, and L.A. Schroeder Spinal and supraspinal sites for morphine and nefopam analgesia in the mouse Eur. J. Pharmacol. 74 1981 135 140
37. S. Pieretti, V. Dal Piaz, R. Matucci, M.P. Giovannoni, and A. Galli Antinociceptive activity of a 3(2H)-pyridazinone derivative in mice Life Sci. 65 1999 1381 1394
38. R.B. Raffa Antihistamines as analgesics J. Clin. Pharm. Ther. 26 2001 81 85
39. J.H. Rosland, and K. Hole The effect of nefopam and its enantiomers on the uptake of 5-hydroxytryptamine, noradrenaline and dopamine in crude rat brain synaptosomal preparations J. Pharm. Pharmacol. 42 1990 437 438
40. M.M. Rumore, and D.A. Schlichting Analgesic effects of antihistaminics Life Sci. 36 1985 403 416
41. E. Schlicker, R. Betz, and M. Gothert Histamine H3 receptor-mediated inhibition of serotonin release in the rat brain cortex Naunyn-Schmiedeberg's Arch. Pharmacol. 337 1988 588 590
42. E. Schlicker, K. Fink, M. Hinterthaner, and M. Gothert Inhibition of noradrenaline release in the rat brain cortex via presynaptic H3 receptors Naunyn-Schmiedeberg's Arch. Pharmacol. 340 1989 633 638
43. E. Schlicker, K. Fink, M. Detzner, and M. Gothert Histamine inhibits dopamine release in the mouse striatum via presynaptic H3 receptors J. Neural Transm. Gen. Sect. 93 1993 1 10
44. J.C. Schwartz, J.M. Arrang, M. Garbarg, and M. Korner Properties and roles of the three subclasses of histamine receptors in brain J. Exp. Biol. 124 1986 203 224
45. S.J. Taylor, A.D. Michel, and G.J. Kilpatrick In vivo occupancy of histamine H3 receptors by thioperamide and (R)-alpha-methylhistamine measured using histamine turnover and an ex vivo labeling technique Biochem. Pharmacol. 44 1992 1261 1267
46. N.J. Tresnak-Rustad, and M.E. Wood In vitro biochemical effects of nefopam hydrochloride, a new analgesic agent Biochem. Pharmacol. 30 1981 2847 2850
47. D. Vohora, S.N. Pal, and K.K. Pillai Histaminergic H3-receptors as modulators of CNS function Indian J. Pharmacol. 33 2001 17 28