Characterization of the analgesic and anti-inflammatory activities of ketorolac and its enantiomers in the rat

Journal of Pharmacology and Experimental Therapeutics

Volumn 288, Issue 3, 1999, Pages 1288-1297

  Jett, Mary Frances ^a,b   Ramesha, Chakk S ^a   Brown, Carl D ^a   Chiu, Sophie ^a   Emmett, Caroline ^a   Voronin, Tatyana ^a   Sun, Thomas ^a   O'Yang, Counde ^a   Hunter, John C ^a   Eglen, Richard M ^a   Johnson, Randolph M ^a  

^a ROCHE BIOSCIENCE   (United States)

^b Center for Biological Research   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELECOXIB; DICLOFENAC; INDOMETACIN; KETOROLAC; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN SYNTHASE INHIBITOR;

ALLODYNIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; EDEMA; ENANTIOMER; HYPERALGESIA; INFLAMMATION; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; LIPOPHILICITY; MALE; NOCICEPTION; NONHUMAN; POSTOPERATIVE PAIN; PRIORITY JOURNAL; RAT; STEREOSPECIFICITY;

ACETIC ACID; ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BRAIN; CARRAGEENAN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DISEASE MODELS, ANIMAL; EPOPROSTENOL; ISOENZYMES; KETOROLAC; MALE; MEMBRANE PROTEINS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, SPRAGUE-DAWLEY; STEREOISOMERISM; TOLMETIN;

EID: 0033028718     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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