Naturally occurring cobalamins have antimalarial activity

Journal of Inorganic Biochemistry

Volumn 101, Issue 5, 2007, Pages 764-773

  Chemaly, Susan M ^a   Chen, Chien Teng ^a   van Zyl, Robyn L ^a  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

Haematin; Cobalamin; Haemozoin; Malaria; Vitamin B12

Indexed keywords

BENZIMIDAZOLE DERIVATIVE; CHLOROQUINE; COBALAMIN DERIVATIVE; COBAMAMIDE; CYANOCOBALAMIN; DICYANOCOBINAMIDE; HEMATIN; HEMOZOIN; HYDROGEN; HYDROXOCOBALAMIN; IRON; MECOBALAMIN; METHIONINE SYNTHASE; PROTOPORPHYRIN; QUININE; RIBOSE; SUGAR; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; HUMAN; HUMAN CELL; HYDROGEN BOND; IC 50; MICROBIAL GROWTH; MICROBIAL METABOLISM; MOLECULAR INTERACTION; NONHUMAN; PLASMODIUM FALCIPARUM;

ANIMALS; ANTIMALARIALS; HEMEPROTEINS; HUMANS; MALARIA, FALCIPARUM; PLASMODIUM FALCIPARUM; TETRAZOLIUM SALTS; THIAZOLES; VITAMIN B 12;

PLASMODIUM FALCIPARUM;

EID: 34047174781     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2007.01.006     Document Type: Article

References (81)

1. Warhurst D.C. N. Engl. J. Med. 344 (2001) 299-302
2. Wellems T.E., and Miller L.H. N. Engl. J. Med. 349 (2003) 1496-1498
3. Barnwell J.W., and Galinski M.R. In: Sherman I.W. (Ed). Malaria: Parasite Biology, Pathogenesis and Protection (1998), ASM Press, Washington, DC 93-120
4. Rosenthal P.J., and Meshnik S.R. In: Sherman I.W. (Ed). Malaria: Parasite Biology, Pathogenesis and Protection (1998), ASM Press, Washington, DC 145-158
5. Olliaro P.L., and Goldberg D.E. Parasitol. Today 11 (1995) 294-297
6. Kirk K. Physiol. Rev. 81 (2001) 495-537
7. Bennett T.L., Kosar A.D., Ursos L.M.B., Dzekunov S., Sidhu A.B.S., Fidock D.A., and Roepe P.D. Mol. Biochem. Parasitol. 133 (2004) 99-114
8. Krugliak M., Zhang J., and Ginsburg H. Mol. Biochem. Parasitol. 119 (2002) 249-256
9. Egan T.J. Targets 2 (2003) 115-124
10. Egan T.J. Drug Design Rev. - Online 1 (2004) 93-110
11. Tekwani B.L., and Walker L.A. Comb. Chem. High Throughput Screen. 8 (2005) 63-79
12. Orjieh A.U., Banyal H.S., Chevli R., and Fitch C.D. Science 214 (1981) 667-669
13. Egan T.J., Combrinck J.M., Egan J., Hearne G.R., Marques H.M., Ntenteni S., Sewell B.T., Smith P.J., Taylor D., van Schalkwyk D.A., and Walden J.C. Biochem. J. 365 (2002) 343-347
14. Pagola S., Stephens P.W., Bohle D.S., Kosar A.D., and Madsen S.K. Nature 404 (2000) 307-310
15. Bohle D.S., Kosar A.D., and Stephens P.W. Acta Crystallogr. D 58 (2002) 1752-1756
16. Bohle D.S., Kosar A.D., and Madsen S.K. Biochem. Biophys. Res. Commun. 294 (2002) 132-135
17. Krogstad D.J., and De D. In: Sherman I.W. (Ed). Malaria: Parasite Biology, Pathogenesis and Protection (1998), ASM Press, Washington, DC 331-339
18. Sidhu A.B.S., Verdier-Pinard D., and Fidock D.A. Science 298 (2002) 210-213
19. Wellems T.E. Science 298 (2002) 124-126
20. 12 (1987), W. de Gruyter, Berlin
21. Hughes M.N. The Inorganic Chemistry of Biological Processes. second ed. (1981), Wiley, Chichester
22. Krungkrai J., Webster H.K., and Yuthavong Y. Parasitol. Res. 75 (1989) 512-517
23. 12 (1972), Academic Press, London
24. 12 (1982), Wiley-Interscience, New York
25. Takahashi K., Okawa M., Matsumoto M., Mishima K., Yamadera H., Sasaki M., Ishizuka Y., Yamada K., Higuchi T., Okamoto N., Furuta H., Nakagawa H., Ohta T., Kuroda K., Sugita Y., Inoue Y., Uchimura N., Nagayama H., Miike T., and Kamei K. Psychiat. Clin. Neurosci. 53 (1999) 211-213
26. Institute of Medicine. Food and Nutrition Board. Dietary Reference Intakes: Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin and Choline (1998), National Academy Press, Washington, DC
27. Parapini S., Basilico N., Pasini E., Egan T.J., Olliaro P., Taramelli D., and Monti D. Exp. Parasitol. 96 (2000) 249-256
28. Deharo E., García R.N., Oporto P., Gimenez A., Sauvain M., Jullian V., and Ginsburg H. Exp. Parasitol. 100 (2002) 252-256
29. Biot C., Taramelli D., Forfar-Bares I., Maciejewski L.A., Boyce M., Nowogrocki G., Brocard J.S., Basilico N., Olliaro P., and Egan T.J. Mol. Pharm. 2 (2005) 185-193
30. Jensen J.B., and Trager W. J. Parasitol. 63 (1977) 883-886
31. Lambros C., and Vanderberg J.P. J. Parasitol. 65 (1979) 418-420
32. Desjardins R.E., Carfield C.J., Haynes D.J., and Chulay J.D. Antimicrob. Agents Chemother. 16 (1972) 710-718
33. Mossman T. J. Immunol. Methods 65 (1983) 55-63
34. Kaschula C.H., Egan T.J., Hunter R., Basilico N., Parapini S., Taramelli D., Pasini E., and Monti D. J. Med. Chem. 45 (2002) 3531-3539
35. Brown K.L., and Wu G.-Z. Inorg. Chem. 33 (1994) 4122-4127
36. Brown K.L., Hakimi J.M., and Jacobsen D.W. J. Am. Chem. Soc. 106 (1984) 7894-7899
37. Marques H.M., Brown K.L., and Jacobsen D.W. J. Biol. Chem. 263 (1988) 12378-12383
38. Schlesinger P.H., Krogstad D.J., and Herwaldt B.L. Antimicrob. Agents Chemother. 32 (1988) 793-798
39. Basilico N., Monti D., Olliaro P., and Taramelli D. FEBS Lett. (1997) 297-299
40. Martiney J.A., Cerami A., and Slater A.F.G. Mol. Med. 96 (1996) 236-246
41. Cole K.A., Ziegler J., Evans C.A., and Wright D.W. J. Inorg. Biochem. 78 (2000) 109-115
42. Begum K., Kim H.-S., Kumar V., Stojiljkovic I., and Wataya Y. Parasitol. Res. 90 (2003) 221-224
43. Iyer J.K., Shi L., Shankar A.H., and Sullivan D.J. Mol. Med. 9 (2003) 175-182
44. Ziegler J., Pasierb L., Cole K.A., and Wright D.W. J. Inorg. Biochem. 96 (2003) 478-486
45. Sharma V. Mini Rev. Med. Chem. 5 (2005) 337-351
46. Monti D., Vodopivec B., Basilico N., Olliaro P., and Taramelli D. Biochemistry 38 (1999) 8858-8863
47. Buller R., Peterson M.L., Almarsson O., and Leiserowitz L. Cryst. Growth Des. 2 (2002) 553-562
48. Leed A., DuBay K., Ursos L.M.B., Sears D., de Dios A.C., and Roepe P.D. Biochemistry 41 (2002) 10245-10255
49. Krungkrai J. Parasitology 129 (2004) 511-524
50. Murphy A.D., Doeller J.E., Hearn B., and Lang-Unnasch N. Exp. Parasitol. 87 (1997) 112-120
51. Baldwin D.A., Betterton E.A., and Pratt J.M. S. Afr. J. Chem. 35 (1982) 173-175
52. 12 (1999), Wiley, New York 73-112
53. 12 (1999), Wiley, New York 9-41
54. Randaccio L., Furlan M., Geremia S., Šlouf M., Srnova I., and Toffoli D. Inorg. Chem. 39 (2000) 3403-3413
55. Brown K.L., Zou X., and Marques H.M. J. Mol. Struct. (Theochem) 453 (1998) 209-224
56. Kratky C., Färber G., Gruber K., Wilson K., Dauter Z., Nolting H.-F., Konrat R., and Kräutler B. J. Am. Chem. Soc. 117 (1995) 4654-4670
57. Firth R.A., Hill H.A.O., Pratt J.M., Thorp R.G., and Williams R.J.P. J. Chem. Soc. (A) (1969) 381-386
58. Garau G., Geremia S., Marzilli L.G., Nardin G., Randaccio L., and Tauzher G. Acta Crystallogr. B 59 (2003) 51-59
59. Saliba K.J., and Kirk K. Int. J. Parasitol. 31 (2001) 1321-1330
60. Linnel J.C. In: Babior B.M. (Ed). Cobalamin: Biochemistry and Pathophysiology (1975), Wiley-Interscience, New York 287-333
61. Herbert V., and Sullivan L.W. Ann. N.Y. Acad. Sci. 112 (1964) 855-870
62. Seetharam B. Annu. Rev. Nutr. 19 (1999) 173-195
63. Babior B.M. In: Lichtman M.A., Beutler E., Kipps T.J., Seligsohn U., Kaushansky K., and Prchal J.T. (Eds). Williams Hematology. seventh ed. (2006), McGraw-Hill, USA
64. Yamanishi M., Vlasie M., and Banerjee R. Trends Biochem. Sci. 30 (2005) 304-308
65. Retief F.P., Gottlieb C.W., and Herbert V. J. Clin. Invest. 45 (1966) 1907-1915
66. Rodriguez M.H., and Jungery M. Nature 324 (1986) 388-391
67. Ginsburg H., and Stein W.D. Trends Parasitol. 21 (2005) 118-121
68. Pouvelle B., Spiegel R., Hsiao L., Howard R.J., Morris R.L., Thomas A.P., and Taraschi T.F. Nature 353 (1991) 73-75
69. van Zyl R.L., Havlik I., Hempelmann E., MacPhail A.P., and McNamara L. Biochem. Pharmcol. 45 (1993) 1431-1436
70. Fritsh G., and Jung A. Z. Parasitenkd. 72 (1986) 709-713
71. Nzila A., Ward S.A., Marsh K., Sims P.F.G., and Hyde J.E. Trends Parasitol. 21 (2005) 292-298
72. Nzila A., Ward S.A., Marsh K., Sims P.F.G., and Hyde J.E. Trends Parasitol. 21 (2005) 334-339
73. Krungkrai J., Webster H.K., and Yuthavong Y. Mol. Biochem. Parasitol. 32 (1989) 25-37
74. Asawamahasakda W., and Yuthavong Y. Parasitology 107 (1993) 1-10
75. Krungkrai J., Webster H.K., and Yuthavong Y. Parasitol. Today 6 (1990) 388-391
76. Divo A.A., Geary T.G., Davis N.L., and Jensen J.B. J. Protozool. 32 (1985) 59-64
77. Schuster F.L. Clin. Microbiol. Rev. 15 (2002) 355-364
78. Saliba K.J., Ferru I., and Kirk K. Antimicrob. Agents Chemother. 49 (2005) 632-637
79. Akompong T., Ghori N., and Haldar K. Antimicrob. Agents Chemother. 44 (2000) 88-96
80. Hamzah J., Skinner-Adams T.S., and Davis T.M.E. Acta Trop. 87 (2003) 345-353
81. Russel-Jones G., McTavish K., McEwan J., Rice J., and Nowotnik D. J. Inorg. Biochem. 98 (2004) 1625-1633