Plasmodium chloroquine resistance and the search for a replacement antimalarial drug

Science

Volumn 298, Issue 5591, 2002, Pages 124-126

  Wellems, Thomas E ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL ENGINEERING; DRUG THERAPY; GENETIC ENGINEERING;

MALARIA;

PHARMACODYNAMICS;

4 AMINOQUINOLINE DERIVATIVE; AMODIAQUINE; ANTIMALARIAL AGENT; ARTEMISININ DERIVATIVE; ATOVAQUONE; ATOVAQUONE PLUS PROGUANIL; CHLOROQUINE; CLINDAMYCIN; FANSIDAR; FOSMIDOMYCIN; HEME; PROGUANIL; PYRIMETHAMINE; PYRONARIDINE; QUININE DERIVATIVE; SULFADOXINE; TERT BUTYLAMODIAQUINE; UNCLASSIFIED DRUG;

DISEASE CONTROL; GLOBAL PERSPECTIVE; MALARIA;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ANTIMALARIAL ACTIVITY; BIOCHEMISTRY; DRUG EFFICACY; DRUG MECHANISM; DRUG RESEARCH; DRUG STRUCTURE; DRUG TARGETING; GENE MUTATION; GENETICS; GENOMICS; HOST RESISTANCE; HUMAN; MALARIA; PLASMODIUM; PRIORITY JOURNAL; PROTEOMICS; SHORT SURVEY;

ALLELES; ANIMALS; ANTIMALARIALS; ATP-BINDING CASSETTE TRANSPORTERS; CHLOROQUINE; DATABASES, NUCLEIC ACID; DRUG RESISTANCE; EVOLUTION; GENES, PROTOZOAN; GENOME, PROTOZOAN; HEME; HUMANS; MALARIA; MALARIA, FALCIPARUM; MEMBRANE PROTEINS; PLASMODIUM; PLASMODIUM FALCIPARUM; POINT MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTOZOAN PROTEINS; SELECTION (GENETICS); SEQUENCE ANALYSIS, DNA; VARIATION (GENETICS);

CINCHONA PUBESCENS;

EID: 0037020111     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1078167     Document Type: Short Survey

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