메뉴 건너뛰기




Volumn 3, Issue 1, 2007, Pages 17-24

The HOX gene network as a potential target for cancer therapy

Author keywords

Antisense oligonucleotides; Breast cancer; Kidney cancer; RNA interference (RNAi); Tritorax genes

Indexed keywords

ANTINEOPLASTIC AGENT; ANTISENSE OLIGONUCLEOTIDE; CYCLIC AMP; CYTOKERATIN; FOMIVIRSEN; HOX PROTEIN; ONCOPROTEIN; REGULATOR PROTEIN; SMALL INTERFERING RNA; TAMOXIFEN; UROKINASE; VASCULOTROPIN;

EID: 34047122624     PISSN: 15733947     EISSN: None     Source Type: Journal    
DOI: 10.2174/157339407780126593     Document Type: Review
Times cited : (3)

References (75)
  • 1
    • 0033215443 scopus 로고    scopus 로고
    • Looping versus linking: Toward a model for long-distance gene activation
    • Bulger M, Groudine M. Looping versus linking: toward a model for long-distance gene activation. Genes Dev 1999; 13: 2465-77.
    • (1999) Genes Dev , vol.13 , pp. 2465-2477
    • Bulger, M.1    Groudine, M.2
  • 2
    • 0038613098 scopus 로고    scopus 로고
    • A global control region defines a chromosomal regulatory landscape containing the HoxD cluster
    • Spitz F, Gonzalez F, Duboule D. A global control region defines a chromosomal regulatory landscape containing the HoxD cluster. Cell 2003; 113: 405-417.
    • (2003) Cell , vol.113 , pp. 405-417
    • Spitz, F.1    Gonzalez, F.2    Duboule, D.3
  • 3
    • 33646936285 scopus 로고    scopus 로고
    • Bone formation: The nuclear matrix reloaded
    • Ellies DL, Krumlauf R. Bone formation: The nuclear matrix reloaded. Cell 2006; 125: 840-2.
    • (2006) Cell , vol.125 , pp. 840-842
    • Ellies, D.L.1    Krumlauf, R.2
  • 4
    • 33744825223 scopus 로고    scopus 로고
    • Genes commute to factories before they start work
    • Pennisi E. Genes commute to factories before they start work. Science 2006; 312: 1304.
    • (2006) Science , vol.312 , pp. 1304
    • Pennisi, E.1
  • 5
    • 8844265508 scopus 로고    scopus 로고
    • Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins
    • Ringrose L, Paro R. Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins. Annu Rev Genet 2004; 38: 413-43.
    • (2004) Annu Rev Genet , vol.38 , pp. 413-443
    • Ringrose, L.1    Paro, R.2
  • 6
    • 33646519677 scopus 로고    scopus 로고
    • Cellular memory and dynamic regulation of polycomb group proteins
    • Bantignies F, Cavalli G. Cellular memory and dynamic regulation of polycomb group proteins. Curr Opin Cell Biol 2006; 18: 275-83.
    • (2006) Curr Opin Cell Biol , vol.18 , pp. 275-283
    • Bantignies, F.1    Cavalli, G.2
  • 7
    • 0018240421 scopus 로고
    • A gene complex controlling segmentation in Drosophila
    • Lewis EB. A gene complex controlling segmentation in Drosophila. Nature 1978; 276: 565-70.
    • (1978) Nature , vol.276 , pp. 565-570
    • Lewis, E.B.1
  • 8
    • 0026489523 scopus 로고
    • Vertebrate homeobox gene nomenclature
    • Scott MP. Vertebrate homeobox gene nomenclature. Cell 1992; 71: 551-3.
    • (1992) Cell , vol.71 , pp. 551-553
    • Scott, M.P.1
  • 9
    • 0024589805 scopus 로고
    • The murine and Drosophila homeobox gene complexes have common features of organization and expression
    • Graham A, Papalopulu N, Krumlauf R. The murine and Drosophila homeobox gene complexes have common features of organization and expression. Cell 1989; 57: 367-378.
    • (1989) Cell , vol.57 , pp. 367-378
    • Graham, A.1    Papalopulu, N.2    Krumlauf, R.3
  • 10
    • 0027105112 scopus 로고
    • Xenopus Hox-2 genes are expressed sequentially after the onset of gastrulation and are differentially inducible by retinoic acid
    • Dekker EJ, Pannese M, Houtzager E, Timmermans A, Boncinelli E, Durston A. Xenopus Hox-2 genes are expressed sequentially after the onset of gastrulation and are differentially inducible by retinoic acid. Dev Suppl 1992; 195-202.
    • (1992) Dev Suppl , pp. 195-202
    • Dekker, E.J.1    Pannese, M.2    Houtzager, E.3    Timmermans, A.4    Boncinelli, E.5    Durston, A.6
  • 11
    • 0029959163 scopus 로고    scopus 로고
    • Patterning the vertebrate neuraxis
    • Lumsden A, Krumlauf R. Patterning the vertebrate neuraxis. Science 1996; 274: 1109-1115.
    • (1996) Science , vol.274 , pp. 1109-1115
    • Lumsden, A.1    Krumlauf, R.2
  • 12
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • Lander ES, Linton LM, Birren B, et al. Initial sequencing and analysis of the human genome. Nature 2001; 409: 860-921.
    • (2001) Nature , vol.409 , pp. 860-921
    • Lander, E.S.1    Linton, L.M.2    Birren, B.3
  • 13
    • 0028674560 scopus 로고
    • HOX Genes in Human Cancers
    • Cillo C. HOX Genes in Human Cancers. Invasion and Metastasis 1994-95; 14: 38-49.
    • (1994) Invasion and Metastasis , vol.14 , pp. 38-49
    • Cillo, C.1
  • 14
    • 0000608460 scopus 로고
    • Genetic control of wing disc development in Drosophila
    • Elsevier, Amsterdam
    • Garcia-Bellido A. Genetic control of wing disc development in Drosophila. Volume 29, CIBA Foundation Symposium Edition: Elsevier, Amsterdam 1975.
    • (1975) CIBA Foundation Symposium Edition , vol.29
    • Garcia-Bellido, A.1
  • 15
    • 0031046014 scopus 로고    scopus 로고
    • Hox genes, arms and the man
    • Scott MP. Hox genes, arms and the man. Nature 1997; 15: 117-118.
    • (1997) Nature , vol.15 , pp. 117-118
    • Scott, M.P.1
  • 16
    • 0242297821 scopus 로고    scopus 로고
    • Beypnd homeosis- HOX function in morphogenesis and organogenesis
    • Castelli-Gair Hombria J, Lovergrove B. Beypnd homeosis- HOX function in morphogenesis and organogenesis. Differentiation 2003; 71: 461-476.
    • (2003) Differentiation , vol.71 , pp. 461-476
    • Castelli-Gair, H.J.1    Lovergrove, B.2
  • 19
    • 1542682335 scopus 로고    scopus 로고
    • HOX genes: Emerging stars in cancer
    • Chen H, Sukumar S. HOX genes: emerging stars in cancer. Cancer Biol Ther 2003; 2: 524-5.
    • (2003) Cancer Biol Ther , vol.2 , pp. 524-525
    • Chen, H.1    Sukumar, S.2
  • 20
    • 0034702232 scopus 로고    scopus 로고
    • Compromised HOXA5 function can limit p53 expression in human breast tumours
    • Raman V, Martensen SA, Reisman D, et al. Compromised HOXA5 function can limit p53 expression in human breast tumours. Nature 2000; 405: 974-978.
    • (2000) Nature , vol.405 , pp. 974-978
    • Raman, V.1    Martensen, S.A.2    Reisman, D.3
  • 22
    • 2942578063 scopus 로고    scopus 로고
    • A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen
    • Ma XJ, Wang Z, Ryan PD, et al. A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen. Cancer Cell 2004; 5: 607-16.
    • (2004) Cancer Cell , vol.5 , pp. 607-616
    • Ma, X.J.1    Wang, Z.2    Ryan, P.D.3
  • 23
    • 0036731788 scopus 로고    scopus 로고
    • Revision of the American Joint Committee on Cancer staging system for breast cancer
    • Singletary SE, Allred C, Ashley P, et al. Revision of the American Joint Committee on Cancer staging system for breast cancer. J Clin Oncol 2002; 20: 3628-36.
    • (2002) J Clin Oncol , vol.20 , pp. 3628-3636
    • Singletary, S.E.1    Allred, C.2    Ashley, P.3
  • 24
    • 0033910732 scopus 로고    scopus 로고
    • Histologic grading of breast cancer: Linkage of patient outcome with level of pathologist agreement
    • Dalton LW, Pinder SE, Elston CE, et al. Histologic grading of breast cancer: linkage of patient outcome with level of pathologist agreement. Mod Pathol 2000; 13: 730-5.
    • (2000) Mod Pathol , vol.13 , pp. 730-735
    • Dalton, L.W.1    Pinder, S.E.2    Elston, C.E.3
  • 25
    • 0030726659 scopus 로고    scopus 로고
    • Laser capture microdissection: Molecular analysis of tissue
    • Bonner RF, Emmert-Buck M, Cole K, et al. Laser capture microdissection: molecular analysis of tissue. Science 1997; 278: 1481-1483.
    • (1997) Science , vol.278 , pp. 1481-1483
    • Bonner, R.F.1    Emmert-Buck, M.2    Cole, K.3
  • 26
    • 0142103778 scopus 로고    scopus 로고
    • Hyperexpression of locus C genes in the HOX network is strongly associated in vivo with human bladder transitional cell carcinomas
    • Cantile M, Cindolo L, Napodano G, Altieri V, Cillo C. Hyperexpression of locus C genes in the HOX network is strongly associated in vivo with human bladder transitional cell carcinomas. Oncogene 2003; 22: 6462-8.
    • (2003) Oncogene , vol.22 , pp. 6462-6468
    • Cantile, M.1    Cindolo, L.2    Napodano, G.3    Altieri, V.4    Cillo, C.5
  • 27
    • 85047697635 scopus 로고    scopus 로고
    • Amplification pattern of 12q13-q15 genes (MDM2, CDK4, GLI) in urinary bladder cancer
    • Simon R, Struckmann K, Schraml P, et al. Amplification pattern of 12q13-q15 genes (MDM2, CDK4, GLI) in urinary bladder cancer. Oncogene 2002; 21: 2476-83.
    • (2002) Oncogene , vol.21 , pp. 2476-2483
    • Simon, R.1    Struckmann, K.2    Schraml, P.3
  • 30
    • 0025258932 scopus 로고
    • The mouse keratin 19-encoding gene: Sequence, structure and chromosomal assign
    • Lussier M, Filion M, Compton JG, Nadeau JH, Lapointe L, Royal A. The mouse keratin 19-encoding gene: sequence, structure and chromosomal assign. Gene 1990; 95: 203-13.
    • (1990) Gene , vol.95 , pp. 203-213
    • Lussier, M.1    Filion, M.2    Compton, J.G.3    Nadeau, J.H.4    Lapointe, L.5    Royal, A.6
  • 31
    • 0023759089 scopus 로고
    • Cytokeratins in normal and malignant transitional epithelium. Maintenance of expression of urothelial differentiation features in transitional cell carcinomas and bladder carcinoma cell culture lines
    • Moll. I, Achtstatter T, Becht E, Balcarova-Stander J, Ittensohn M, Franke WW. Cytokeratins in normal and malignant transitional epithelium. Maintenance of expression of urothelial differentiation features in transitional cell carcinomas and bladder carcinoma cell culture lines. Am J Pathol 1988; 132: 123-44.
    • (1988) Am J Pathol , vol.132 , pp. 123-144
    • Moll, I.1    Achtstatter, T.2    Becht, E.3    Balcarova-Stander, J.4    Ittensohn, M.5    Franke, W.W.6
  • 32
    • 0031930016 scopus 로고    scopus 로고
    • The mouse Hoxc11 gene: Genomic structure and expression pattern
    • Hostikka SL, Capecchi MR. The mouse Hoxc11 gene: genomic structure and expression pattern. Mech Dev 1998; 70: 133-45.
    • (1998) Mech Dev , vol.70 , pp. 133-145
    • Hostikka, S.L.1    Capecchi, M.R.2
  • 33
    • 19044391072 scopus 로고    scopus 로고
    • Gene expression correlates of clinical prostate cancer behavior
    • Singh D, Febbo PG, Ross K, et al. Gene expression correlates of clinical prostate cancer behavior. Cancer Cell 2002; 1: 203-9.
    • (2002) Cancer Cell , vol.1 , pp. 203-209
    • Singh, D.1    Febbo, P.G.2    Ross, K.3
  • 34
    • 26444437309 scopus 로고    scopus 로고
    • cAMP induced modifications of HOX D gene expression in prostate cells allow the identification of a chromosomal area involved in vivo with neuroendocrine differentiation of human advanced prostate cancers
    • Cantile M, Kisslinger A, Cindolo L, et al. cAMP induced modifications of HOX D gene expression in prostate cells allow the identification of a chromosomal area involved in vivo with neuroendocrine differentiation of human advanced prostate cancers. J Cell Physiol 2005; 205: 202-10.
    • (2005) J Cell Physiol , vol.205 , pp. 202-210
    • Cantile, M.1    Kisslinger, A.2    Cindolo, L.3
  • 35
    • 0028356553 scopus 로고
    • Terminal neuroendocrine differentiation of human prostate carcinoma cells in response to increased intracellular cyclic AMP
    • Bang YJ, Pirnia F, Fang WG, et al. Terminal neuroendocrine differentiation of human prostate carcinoma cells in response to increased intracellular cyclic AMP. Proc Natl Acad Sci U S A 1994; 91: 5330-5334.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 5330-5334
    • Bang, Y.J.1    Pirnia, F.2    Fang, W.G.3
  • 36
    • 0034901655 scopus 로고    scopus 로고
    • Interleukin-6 induces androgen responsiveness in prostate cancer cells through upregulation of androgen receptor expression
    • Lin DL, Whitney MC, Yao Z, Keller ET. Interleukin-6 induces androgen responsiveness in prostate cancer cells through upregulation of androgen receptor expression. Clin Cancer Res 2001; 7: 1773-1781.
    • (2001) Clin Cancer Res , vol.7 , pp. 1773-1781
    • Lin, D.L.1    Whitney, M.C.2    Yao, Z.3    Keller, E.T.4
  • 37
    • 2942694533 scopus 로고    scopus 로고
    • A dual role for Hox genes in limb anterior-posterior asymmetry
    • Zakany J, Kmita M, Duboule D. A dual role for Hox genes in limb anterior-posterior asymmetry. Science 2004; 304: 1669-1672.
    • (2004) Science , vol.304 , pp. 1669-1672
    • Zakany, J.1    Kmita, M.2    Duboule, D.3
  • 38
    • 0030902178 scopus 로고    scopus 로고
    • Male accessory sex organ morphogenesis is altered by loss of function of Hoxd-13
    • Podlasek CA, Duboule D, Bushman W. Male accessory sex organ morphogenesis is altered by loss of function of Hoxd-13. Dev Dyn 1997; 208: 454-465.
    • (1997) Dev Dyn , vol.208 , pp. 454-465
    • Podlasek, C.A.1    Duboule, D.2    Bushman, W.3
  • 39
    • 10744225687 scopus 로고    scopus 로고
    • Elevated expression of PCGEM1, a prostate-specific gene with cell growth-promoting function, is associated with high-risk prostate cancer patients
    • Petrovics G, Zhang W, Makarem M, et al. Elevated expression of PCGEM1, a prostate-specific gene with cell growth-promoting function, is associated with high-risk prostate cancer patients. Oncogene 2004; 23: 605-611.
    • (2004) Oncogene , vol.23 , pp. 605-611
    • Petrovics, G.1    Zhang, W.2    Makarem, M.3
  • 40
    • 0032406199 scopus 로고    scopus 로고
    • CCG repeats in cDNAs from human brain
    • Kleiderlein JJ, Nisson PE, Jessee J, et al. CCG repeats in cDNAs from human brain. Hum Genet 1998; 103: 666-673.
    • (1998) Hum Genet , vol.103 , pp. 666-673
    • Kleiderlein, J.J.1    Nisson, P.E.2    Jessee, J.3
  • 41
    • 1442311558 scopus 로고    scopus 로고
    • A conserved developmental program for sensory organ formation in Drosophila melanogaster
    • Niwa N, Hiromi Y, Okabe M. A conserved developmental program for sensory organ formation in Drosophila melanogaster. Nat Gen 2004; 36: 293-297.
    • (2004) Nat Gen , vol.36 , pp. 293-297
    • Niwa, N.1    Hiromi, Y.2    Okabe, M.3
  • 42
  • 43
    • 2342501365 scopus 로고    scopus 로고
    • Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization
    • Casolari JM, Brown CR, Komili S, West J, Hieronymus H, Silver PA. Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization. Cell 2004; 117: 427-39.
    • (2004) Cell , vol.117 , pp. 427-439
    • Casolari, J.M.1    Brown, C.R.2    Komili, S.3    West, J.4    Hieronymus, H.5    Silver, P.A.6
  • 44
    • 5444260778 scopus 로고    scopus 로고
    • Spatial positioning; a new dimension in genome function
    • Misteli T. Spatial positioning; a new dimension in genome function. Cell 2004; 119: 153-6.
    • (2004) Cell , vol.119 , pp. 153-156
    • Misteli, T.1
  • 45
    • 0029068316 scopus 로고
    • Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein
    • Lee JE, Hollenberg SM, Snider L, Turner DL, Lipnick N, Weintraub H. Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein. Science 1995; 268: 836-844.
    • (1995) Science , vol.268 , pp. 836-844
    • Lee, J.E.1    Hollenberg, S.M.2    Snider, L.3    Turner, D.L.4    Lipnick, N.5    Weintraub, H.6
  • 46
    • 34047135628 scopus 로고    scopus 로고
    • NeuroD1 expression in human prostate cancer: Can it contribute to neuroendocrine differentiation comprehension?
    • PHID 17126478
    • Cindolo L, Franco R, Cantile M, Botti G, Gallo A, Cillo. C. NeuroD1 expression in human prostate cancer: can it contribute to neuroendocrine differentiation comprehension? Eur Urol 2006; PHID 17126478.
    • (2006) Eur Urol
    • Cindolo, L.1    Franco, R.2    Cantile, M.3    Botti, G.4    Gallo, A.5    Cillo, C.6
  • 47
    • 0003731497 scopus 로고
    • Organogenesis of the kidney
    • Cambridge Univ. Press, Cambridge, UK
    • Saxèn L. Organogenesis of the kidney. Cambridge Univ. Press, Cambridge, UK 1987; 1-173.
    • (1987) , pp. 1-173
    • Saxèn, L.1
  • 48
    • 0003695294 scopus 로고
    • Normal and abnormal development of the kidney
    • Year Book Medical publishers Inc, Chicago
    • Potter EL. Normal and abnormal development of the kidney. Year Book Medical publishers Inc, Chicago 1972.
    • (1972)
    • Potter, E.L.1
  • 49
    • 0034948886 scopus 로고    scopus 로고
    • Hoxa11 and Hoxd11 regulate branching morphogenesis of ureteric bud in the developing kidney
    • Patterson LT, Pembaur M, Potter SS. Hoxa11 and Hoxd11 regulate branching morphogenesis of ureteric bud in the developing kidney. Development 2001; 128: 2153-2161.
    • (2001) Development , vol.128 , pp. 2153-2161
    • Patterson, L.T.1    Pembaur, M.2    Potter, S.S.3
  • 50
    • 0027182741 scopus 로고
    • Wtl is required for early kidney development
    • Kreidberg JA, Sariola H, Loring JM, et al. Wtl is required for early kidney development. Cell 1993; 74: 679-691.
    • (1993) Cell , vol.74 , pp. 679-691
    • Kreidberg, J.A.1    Sariola, H.2    Loring, J.M.3
  • 51
    • 0029590072 scopus 로고
    • Pax2 controls multiple steps of urogenital development
    • Torres M, Gomez-Pardo E, Dressler GR, Gruss P. Pax2 controls multiple steps of urogenital development. Development 1995; 121: 4057-4065.
    • (1995) Development , vol.121 , pp. 4057-4065
    • Torres, M.1    Gomez-Pardo, E.2    Dressler, G.R.3    Gruss, P.4
  • 52
    • 0034840126 scopus 로고    scopus 로고
    • Murine homolog of SALL1 is essential for ureteric bud invasion in kidney development
    • Nishinakamura R, Matsumoto Y, Nakao K, et al. Murine homolog of SALL1 is essential for ureteric bud invasion in kidney development Development 2001; 128: 3105-3115.
    • (2001) Development , vol.128 , pp. 3105-3115
    • Nishinakamura, R.1    Matsumoto, Y.2    Nakao, K.3
  • 53
    • 0034092938 scopus 로고    scopus 로고
    • Murine forkhead/winged helix genes Foxc1 (Mf1) and Foxc2 (Mfh1) are required for the early organo-genesis of the kidney and urinary tract
    • Kume T, Deng K, Hogan BL. Murine forkhead/winged helix genes Foxc1 (Mf1) and Foxc2 (Mfh1) are required for the early organo-genesis of the kidney and urinary tract. Development 2000; 127: 1387-1395.
    • (2000) Development , vol.127 , pp. 1387-1395
    • Kume, T.1    Deng, K.2    Hogan, B.L.3
  • 54
    • 0032842838 scopus 로고    scopus 로고
    • Eyal-deficient mice lack ears and kidneys and show abnormal apoptosis oforgan primordia
    • Xu PX, Adams J, Peters H, Brown MC, Heaney S, Maas R. Eyal-deficient mice lack ears and kidneys and show abnormal apoptosis oforgan primordia. Nat Genet 1999; 23: 113-117.
    • (1999) Nat Genet , vol.23 , pp. 113-117
    • Xu, P.X.1    Adams, J.2    Peters, H.3    Brown, M.C.4    Heaney, S.5    Maas, R.6
  • 55
    • 0036219713 scopus 로고    scopus 로고
    • Genes and proteins in renal development
    • Davies JA, Fisher CE. Genes and proteins in renal development. Exp Nephrol 2002; 10: 102-113.
    • (2002) Exp Nephrol , vol.10 , pp. 102-113
    • Davies, J.A.1    Fisher, C.E.2
  • 56
    • 15844426332 scopus 로고    scopus 로고
    • Defects in enteric innervation and kidney development in mice lacking GDNF
    • Pichel JG, Shen L, Sheng HZ, et al. Defects in enteric innervation and kidney development in mice lacking GDNF. Nature 1996; 382: 73-76.
    • (1996) Nature , vol.382 , pp. 73-76
    • Pichel, J.G.1    Shen, L.2    Sheng, H.Z.3
  • 57
    • 0028174023 scopus 로고
    • Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret
    • Schuchardt A, D'Agati V, Larsson-Blomberg L, Costantini F, Pachnis V. Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret. Nature 1994; 367: 380-383.
    • (1994) Nature , vol.367 , pp. 380-383
    • Schuchardt, A.1    D'Agati, V.2    Larsson-Blomberg, L.3    Costantini, F.4    Pachnis, V.5
  • 58
    • 0032114122 scopus 로고    scopus 로고
    • GFRalphal is an essencial receptor component for GDNF in the developing nervous system and kidney
    • Cacalano G, Farinas I, Wang LC, et al. GFRalphal is an essencial receptor component for GDNF in the developing nervous system and kidney. Neuron 1998; 2: 53-62.
    • (1998) Neuron , vol.2 , pp. 53-62
    • Cacalano, G.1    Farinas, I.2    Wang, L.C.3
  • 59
    • 0028588919 scopus 로고
    • Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4
    • Stark K, Vaino S, Vassileva G, McMahon AP. Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature 1994; 372: 679-683.
    • (1994) Nature , vol.372 , pp. 679-683
    • Stark, K.1    Vaino, S.2    Vassileva, G.3    McMahon, A.P.4
  • 60
    • 0036606196 scopus 로고    scopus 로고
    • Hox11 paralogous genes are essencial for metanephric kidney induction
    • Wellik DM, Hawkes PJ, Capecchi MR, Hox11 paralogous genes are essencial for metanephric kidney induction. Genes Dev 2002; 16: 1423-1432.
    • (2002) Genes Dev , vol.16 , pp. 1423-1432
    • Wellik, D.M.1    Hawkes, P.J.2    Capecchi, M.R.3
  • 61
    • 0031466723 scopus 로고    scopus 로고
    • Gene dosage-dependent effects of the Hox a13 and Hox d13 mutations on morphogenesis of the terminal parts of the digestive and urogenital tracts
    • Warot X, Fromental-Ramain C, Fraulob V, Chambon P, Dollè P. Gene dosage-dependent effects of the Hox a13 and Hox d13 mutations on morphogenesis of the terminal parts of the digestive and urogenital tracts. Development 1997; 124: 4781-4791.
    • (1997) Development , vol.124 , pp. 4781-4791
    • Warot, X.1    Fromental-Ramain, C.2    Fraulob, V.3    Chambon, P.4    Dollè, P.5
  • 62
    • 0033536244 scopus 로고    scopus 로고
    • CBP and histone deacetylase inhibition enhance the transactivation potential of the HOXB7 homeodomain-containing protein
    • Chariot A, van Lint C, Chapelier M, Gielen J, Merville MP, Bours V. CBP and histone deacetylase inhibition enhance the transactivation potential of the HOXB7 homeodomain-containing protein. Oncogene 1999; 18: 4007-14.
    • (1999) Oncogene , vol.18 , pp. 4007-4014
    • Chariot, A.1    van Lint, C.2    Chapelier, M.3    Gielen, J.4    Merville, M.P.5    Bours, V.6
  • 63
    • 0035834382 scopus 로고    scopus 로고
    • Trithorax and dCBP acting in a complex to maintain expression of a homeotic gene
    • Petruk S, Sedkov Y, Smith S, et al. Trithorax and dCBP acting in a complex to maintain expression of a homeotic gene. Science 2001; 294: 1331-4.
    • (2001) Science , vol.294 , pp. 1331-1334
    • Petruk, S.1    Sedkov, Y.2    Smith, S.3
  • 64
    • 0035102477 scopus 로고    scopus 로고
    • MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein
    • Ernst P, Wang J, Huang M, Goodman RH, Korsmeyer SJ. MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein. Mol Cell Biol 2001; 21: 2249-58.
    • (2001) Mol Cell Biol , vol.21 , pp. 2249-2258
    • Ernst, P.1    Wang, J.2    Huang, M.3    Goodman, R.H.4    Korsmeyer, S.J.5
  • 65
    • 0034796574 scopus 로고    scopus 로고
    • The HOX homeodomain proteins block CBP histone acetyltransferase activity
    • Shen WF, Krishnan K, Lawrence HJ, Largman C. The HOX homeodomain proteins block CBP histone acetyltransferase activity. Mol Cell Biol 2001; 21: 7509-22.
    • (2001) Mol Cell Biol , vol.21 , pp. 7509-7522
    • Shen, W.F.1    Krishnan, K.2    Lawrence, H.J.3    Largman, C.4
  • 66
    • 33646786144 scopus 로고    scopus 로고
    • The role of HOX genes in myeloid leukemogenesis
    • Eklund EA. The role of HOX genes in myeloid leukemogenesis. Curr Opin Hematol 2006; 13: 67-73.
    • (2006) Curr Opin Hematol , vol.13 , pp. 67-73
    • Eklund, E.A.1
  • 67
    • 33746882054 scopus 로고    scopus 로고
    • Gene expression profiling of acute myeloid leukemia with translocation t(8;16)(p11;p13) and MYST3-CREBBP rearrangement reveals a distinctive signature with a specific pattern of HOX gene expression
    • Camos M, Esteve J, Jares P, et al. Gene expression profiling of acute myeloid leukemia with translocation t(8;16)(p11;p13) and MYST3-CREBBP rearrangement reveals a distinctive signature with a specific pattern of HOX gene expression. Cancer Res 2006; 66: 6947-54.
    • (2006) Cancer Res , vol.66 , pp. 6947-6954
    • Camos, M.1    Esteve, J.2    Jares, P.3
  • 68
    • 0028358920 scopus 로고
    • Inhibition of retinoic acid-induced activation of 3′ human HOXB genes by antisense oligonucleotides affects sequential activation of genes located upstream in the four HOX clusters
    • Faiella A, Zappavigna V, Mavilio F, Boncinelli E. Inhibition of retinoic acid-induced activation of 3′ human HOXB genes by antisense oligonucleotides affects sequential activation of genes located upstream in the four HOX clusters. Proc Natl Acad Sci U S A 1994; 91: 5335-9.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 5335-5339
    • Faiella, A.1    Zappavigna, V.2    Mavilio, F.3    Boncinelli, E.4
  • 69
    • 0035158486 scopus 로고    scopus 로고
    • Targeted down-regulation of MLL-AF9 with antisense oligodeoxyribonucleotide reduces the expression of the HOXA7 and -A10 genes and induces apoptosis in a human leukemia cell line THP-1
    • Kawagoe H, Kawagoe R, Sano K. Targeted down-regulation of MLL-AF9 with antisense oligodeoxyribonucleotide reduces the expression of the HOXA7 and -A10 genes and induces apoptosis in a human leukemia cell line THP-1. Leukemia 2001; 15: 1743-9.
    • (2001) Leukemia , vol.15 , pp. 1743-1749
    • Kawagoe, H.1    Kawagoe, R.2    Sano, K.3
  • 70
    • 1842559902 scopus 로고    scopus 로고
    • Homeobox A9 transcriptionally regulates the EphB4 receptor to modulate endothelial cell migration and tube formation
    • Bruhl T, Urbich C, Aicher D, Acker-Palmer A, Zeiher AM, Dimmeler S. Homeobox A9 transcriptionally regulates the EphB4 receptor to modulate endothelial cell migration and tube formation. Circ Res 2004; 94: 743-51.
    • (2004) Circ Res , vol.94 , pp. 743-751
    • Bruhl, T.1    Urbich, C.2    Aicher, D.3    Acker-Palmer, A.4    Zeiher, A.M.5    Dimmeler, S.6
  • 71
    • 25144498128 scopus 로고    scopus 로고
    • In vivo application of RNA interference: From functional genomics to therapeutics
    • Lu PY, Xie F, Woodle MC. In vivo application of RNA interference: from functional genomics to therapeutics, Adv Genet 2005; 54: 117-42.
    • (2005) Adv Genet , vol.54 , pp. 117-142
    • Lu, P.Y.1    Xie, F.2    Woodle, M.C.3
  • 72
    • 14544298301 scopus 로고    scopus 로고
    • Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle
    • Schiffelers RM, Ansari A, Xu J, et al. Cancer siRNA therapy by tumor selective delivery with ligand-targeted. sterically stabilized nanoparticle. Nucleic Acids Res 2004; 32: 149.
    • (2004) Nucleic Acids Res , vol.32 , pp. 149
    • Schiffelers, R.M.1    Ansari, A.2    Xu, J.3
  • 73
    • 2442668068 scopus 로고    scopus 로고
    • A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics
    • Takei Y, Kadomatsu K, Yuzawa Y, Matsuo S, Muramatsu T. A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics. Cancer Res 2004; 64(10): 3365-70.
    • (2004) Cancer Res , vol.64 , Issue.10 , pp. 3365-3370
    • Takei, Y.1    Kadomatsu, K.2    Yuzawa, Y.3    Matsuo, S.4    Muramatsu, T.5
  • 74
    • 33747337000 scopus 로고    scopus 로고
    • Role of Bmil in H2A ubiquitylation and Hox gene silencing
    • Wei J, Zhai L, Xu J, Wang H. Role of Bmil in H2A ubiquitylation and Hox gene silencing. J Biol Chem 2006; 281: 22537-44.
    • (2006) J Biol Chem , vol.281 , pp. 22537-22544
    • Wei, J.1    Zhai, L.2    Xu, J.3    Wang, H.4
  • 75
    • 33751251990 scopus 로고    scopus 로고
    • Small dsRNAs induce transcriptional activation in human cells
    • Li LC, Okino ST, Zhao H, et al. Small dsRNAs induce transcriptional activation in human cells. Proc Natl Acad Sci USA 2006; 103: 17337-42.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 17337-17342
    • Li, L.C.1    Okino, S.T.2    Zhao, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.