Targeted down-regulation of MLL-AF9 with antisense oligodeoxyribonucleotide reduces the expression of the HOXA7 and -A10 genes and induces apoptosis in a human leukemia cell line, THP-1

Leukemia

Volumn 15, Issue 11, 2001, Pages 1743-1749

  Kawagoe, H ^a   Kawagoe, R ^a   Sano, K ^a  

^a KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptosis; HOX; Leukemogenesis; MLL AF9

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; ANTISENSE OLIGODEOXYNUCLEOTIDE; CHIMERIC PROTEIN; HOMEODOMAIN PROTEIN; LIPOCORTIN 5; PROPIDIUM IODIDE;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL COUNT; CELL LINEAGE; CELL STRUCTURE; CELL VIABILITY; CHROMOSOME 11Q; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE REARRANGEMENT; GENE SEQUENCE; GENETIC TRANSCRIPTION; HEMATOPOIESIS; HUMAN; HUMAN CELL; LEUKEMIA; LEUKEMIA CELL; LEUKEMIA CELL LINE; LEUKEMOGENESIS; MONOCYTIC LEUKEMIA; MORPHOGENESIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REGULATORY MECHANISM; STAINING;

EID: 0035158486     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2402262     Document Type: Article

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