Genes and proteins in renal development

Experimental Nephrology

Volumn 10, Issue 2, 2002, Pages 102-113

  Davies, Jamie A ^a   Fisher, Carolyn E ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

BMP; FGF; Genes, kidney development; Integrin; Kidney development; Nephrogenesis; Ret; Wnt

Indexed keywords

BIOLOGICAL FACTOR; BIOLOGICAL FACTOR LIF; BONE MORPHOGENETIC PROTEIN; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; FRP 1 RECEPTOR; FRP 2 RECEPTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GLYCOSAMINOGLYCAN; GROWTH FACTOR; METHIONINE; NOTCH RECEPTOR; OSTEOGENIC PROTEIN 1; PROTEIN; PROTEIN WT 1; RECEPTOR; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR D11; TRANSCRIPTION FACTOR EMX 2; TRANSCRIPTION FACTOR EYA 1; TRANSCRIPTION FACTOR FOXC 1; TRANSCRIPTION FACTOR HOXA11; TRANSCRIPTION FACTOR LIM 1; TRANSCRIPTION FACTOR PAX 2; TRANSCRIPTION FACTOR WT 1; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA2; UNCLASSIFIED DRUG; UNINDEXED DRUG; WNT PROTEIN;

APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; EMBRYONIC STRUCTURES; EPITHELIUM CELL; GENE; KIDNEY DEVELOPMENT; KIDNEY INTERSTITIUM; NEPHRON; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; STROMA;

EID: 0036219713     PISSN: 10187782     EISSN: None     Source Type: Journal    
DOI: 10.1159/000049905     Document Type: Article

References (96)

1. Renal agenesis and dysgenesis
2. Expression patterns of the murine LIM class homeobox gene lim1 in the developing brain and excretory system
3. Lim1 activity is required for intermediate mesoderm differentiation in the mouse embryo
4. Pax2 controls multiple steps of urogenital development
5. Functional equivalence of the transcription factors Pax2 and Pax5 in mouse development
6. Characterization of three novel members of the zebrafish Pax2/5/8 family: Dependency of Pax5 and Pax8 expression on the Pax2.1 (noi) function
7. Characterization of an amphioxus paired box gene, AmphiPax2/5/8: Developmental expression patterns in optic support cells, nephridium, thyroid-like structures and pharyngeal gill slits, but not in the midbrain-hindbrain boundary region
8. Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia
9. Murine fork-head/winged helix genes Foxc1 (Mf1) and Foxc2 (Mfh1) are required for the early organogenesis of the kidney and urinary tract
10. Glial cell-line derived neurotrophic factor is required for bud initiation from ureteric epithelium
11. Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret
12. Renal agenesis and hypodysplasia in ret-/-mutant mice result from defects in ureteric bud development
13. Glial cell line-derived neurotrophic factor activates the receptor tyrosine kinase RET and promotes kidney morphogenesis
14. Defects of urogenital development in mice lacking Emx2
15. Essential role of stromal mesenchyme in kidney morphogenesis revealed by targeted disruption of winged helix transcription factor BF-2
16. Stromal cells mediate retinoid-dependent functions essential for renal development
17. Roles of hepatocyte growth factor/scatter factor and the Met receptor in the early development of the metanephros
18. Activation of hepatocyte growth factor (HGF) by endogenous HGF activator is required for metanephric kidney morphogenesis in vitro
19. Sulphated proteoglycan is required for collecting duct growth and branching but not nephron formation during kidney development
20. Scatter factor/hepatocyte growth factor is essential for liver development
21. Comparative role of phosphotyrosine kinase domains of c-ros and c-ret protooncogenes in metanephric development with respect to growth factors and matrix morphogens
22. Bone morphogenetic protein 4 regulates the budding site and elongation of the mouse ureter
23. A requirement for bone morphogenetic protein 7 during development of the mammalian kidney and eye
24. Protein kinase A is a negative regulator of renal branching morphogenesis and modulates inhibitory and stimulatory bone morphogenetic proteins
25. Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1
26. BMP-2/ALK3 and HGF signal in parallel to regulate renal collecting duct morphogenesis
27. Activin disrupts epithelial branching morphogenesis in developing glandular organs of the mouse
28. Deficient outgrowth of the ureteric bud underlies the renal agenesis phenotype in mice manifesting the limb deformity (ld) mutation
29. The role of a single formin isoform in the limb and renal phenotypes of limb deformity
30. Hepatocyte growth factor induces MAPK-dependent formin IV translocation in renal epithelial cells
31. A role for Timeless in epithelial morphogenesis during kidney development
32. Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase
33. Persephin, a neurotrophic factor related to GDNF and neurturin
34. Neurturin: An autocrine regulator of renal collecting duct development
35. Differential regulation of hepatocyte growth factor/scatter factor by cell surface proteoglycans and free glycosaminoglycan chains
36. Role of mesenchymal nidogen for epithelial morphogenesis in vitro
37. Integrin alpha8beta1 is critically important for epithelial-mesenchymal interactions during kidney morphogenesis
38. Matrix metalloproteinases MMP2 and MMP9 are produced in early stages of kidney morphogenesis but only MMP9 is required for renal organogenesis in vitro
39. Gelatinase B (MMP-9) is not essential in the normal kidney and does not influence progression of renal disease in a mouse model of Alport syndrome
40. Tissue inhibitor of metalloproteinase-2 stimulates mesenchymal growth and regulates epithelial branching during morphogenesis of the rat metanephros
41. Large scale normal cell death in the developing rat kidney and its reduction by epidermal growth factor
42. TGF-alpha mRNA expression in renal organogenesis: A study in rat and human embryos
43. Autocrine interaction between TGF alpha and the EGF-receptor: Quantitative requirements for induction of the malignant phenotype
44. Colo-calization of BMP7 and BMP2 mRNAs suggests that these factors cooperatively mediate tissue interactions during murine development
45. Induction of nephrogenic mesenchyme by osteogenic protein 1 (BMP-7)
46. Regulation of BMP7 expression during kidney development
47. Cell-type-specific nuclear translocation of fibroblast growth factor-2 isoforms during chicken kidney and limb morphogenesis
48. Basic fibroblast growth factor can mediate the early inductive events in renal development
49. Mesenchymal to epithelial conversion in rat metanephros is induced by LIF
50. TGF beta 2, LIF and FGF2 cooperate to induce nephrogenesis
51. Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development
52. Isolation, characterisation and embryonic expression of Wnt11, a gene which maps to 11q13.5 and has possible roles in the development of skeleton, kidney and lung
53. Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips
54. A molecular mechanism for the effect of lithium on development
55. Induction of kidney epithelial morphogenesis by cells expressing Wnt-1
56. The candidate Wilms' tumour gene is involved in genitourinary development
57. WT-1 is required for early kidney development
58. Initial differentiation of the metanephric mesenchyme is independent of WT1 and the ureteric bud
59. Wilms tumor and the WT1 gene
60. Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing
61. Pax-2 is required for mesenchyme-to-epithelium conversion during kidney development
62. Absence of radius and ulna in mice lacking hox-a11 and hox-d11
63. Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4
64. Induction of early stages of kidney tubule differentiation by lithium ions
65. Secreted Frizzled-related proteins can regulate metanephric development
66. Differential expression of gap junction mRNAs and proteins in the developing murine kidney and in experimentally induced nephric mesenchymes
67. Early expression of desmosomal components during kidney tubule morphogenesis in human and murine embryos
68. Differential expression and function of cadherin-6 during renal epithelium development
69. Neural cell adhesion molecules during induction and development of the kidney
70. Isolation of complementary DNA encoding K-cadherin, a novel rat cadherin preferentially expressed in foetal kidney and kidney carcinoma
71. In situ hybridization reveals temporal and spatial changes in cellular expression of mRNA for a laminin receptor, laminin, and basement membrane (type IV) collagen in the developing kidney
72. Shift in collagen types as an early response to induction of metanephric mesenchyme
73. Transient and locally restricted expression of laminin A chain mRNA by developing epithelial cells during kidney organogenesis
74. The regulation of kidney development: New insights from an old model
75. Deregulation of Pax-2 expression in transgenic mice generates severe kidney abnormalities
76. Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation
77. Multiple signalling pathways establish cell fate and cell number in Drosophilamalpighian tubules
78. Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria and renal Fanconi syndrome
79. Tubulointerstitial nephritis antigen: An extracellular matrix protein that selectively regulates tubulogenesis vs. glomerulogenesis during mammalian renal development
80. Interaction between FGF and BMP signaling pathways regulates development of metanephric mesenchyme
81. Development and growth of mouse embryonic kidney in organ culture and modulation of development by soluble growth factor
82. Differentiation and vascularization of the metanephric kidney grafted on the chorioallantoic membrane
83. ELK and LERK-2 in developing kidney and microvascular endothelial assembly
84. Evidence that embryonic kidney cells expressing flk-1 are intrinsic, vasculogenic angio-blasts
85. Endogenous origin of glomerular endothelial and mesangial cells in grafts of embryonic kidneys
86. Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation
87. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
88. Vascular endothelial growth factor is an essential molecule for mouse kidney development: Glomerulogenesis and nephrogenesis
89. Vascular endothelial growth factor induces endothelial fenestrations in vitro
90. Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
91. Expression of platelet-derived growth factor and its receptors in the developing and adult mouse kidney
92. Paracrine PDGF-B/PDGF-Rbeta signaling controls mesangial cell development in kidney glomeruli
93. Mice deficient for PDGF-B show renal, cardiovascular, and hematological abnormalities
94. The mouse Pdgfc gene: Dynamic expression in embryonic tissues during organogenesis