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Volumn 176, Issue 7, 2007, Pages 1035-1047

Essential role of PDK1 in regulating endothelial cell migration

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PHOSPHATIDYLINOSITOL KINASE; PHOSPHOINOSITIDE DEPENDENT KINASE 1; PROTEIN KINASE B; UNCLASSIFIED DRUG; VASCULOTROPIN A;

EID: 33947728156     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.200607053     Document Type: Article
Times cited : (70)

References (53)
  • 1
    • 21344464454 scopus 로고    scopus 로고
    • Signaling to cytoskeletal dynamics during chemotaxis
    • Affolter, M., and C.J. Weijer. 2005. Signaling to cytoskeletal dynamics during chemotaxis. Dev. Cell. 9:19-34.
    • (2005) Dev. Cell , vol.9 , pp. 19-34
    • Affolter, M.1    Weijer, C.J.2
  • 2
    • 0031127305 scopus 로고    scopus 로고
    • Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha
    • Alessi, D.R., S.R. James, C.P. Downes, A.B. Holmes, P.R. Gaffney, C.B. Reese, and P. Cohen. 1997. Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha. Curr. Biol. 7:261-269.
    • (1997) Curr. Biol , vol.7 , pp. 261-269
    • Alessi, D.R.1    James, S.R.2    Downes, C.P.3    Holmes, A.B.4    Gaffney, P.R.5    Reese, C.B.6    Cohen, P.7
  • 3
    • 0032482374 scopus 로고    scopus 로고
    • Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B
    • Anderson, K.E., J. Coadwell, L.R. Stephens, and P.T. Hawkins. 1998. Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B. Curr. Biol. 8:684-691.
    • (1998) Curr. Biol , vol.8 , pp. 684-691
    • Anderson, K.E.1    Coadwell, J.2    Stephens, L.R.3    Hawkins, P.T.4
  • 4
    • 13344269588 scopus 로고    scopus 로고
    • A local coupling model and compass parameter for eukaryotic chemotaxis
    • Arrieumerlou, C., and T. Meyer. 2005. A local coupling model and compass parameter for eukaryotic chemotaxis. Dev. Cell. 8:215-227.
    • (2005) Dev. Cell , vol.8 , pp. 215-227
    • Arrieumerlou, C.1    Meyer, T.2
  • 5
    • 0035882103 scopus 로고    scopus 로고
    • The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB
    • Biondi, R.M., A. Kieloch, R.A. Currie, M. Deak, and D.R. Alessi. 2001. The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB. EMBO J. 20:4380-4390.
    • (2001) EMBO J , vol.20 , pp. 4380-4390
    • Biondi, R.M.1    Kieloch, A.2    Currie, R.A.3    Deak, M.4    Alessi, D.R.5
  • 6
    • 0035499454 scopus 로고    scopus 로고
    • Ten years of protein kinase B signalling: A hard Akt to follow
    • Brazil, D.P., and B.A. Hemmings. 2001. Ten years of protein kinase B signalling: a hard Akt to follow. Trends Biochem. Sci. 26:657-664.
    • (2001) Trends Biochem. Sci , vol.26 , pp. 657-664
    • Brazil, D.P.1    Hemmings, B.A.2
  • 8
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • Cantley, L.C. 2002. The phosphoinositide 3-kinase pathway. Science. 296:1655-1657.
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 9
    • 0033199841 scopus 로고    scopus 로고
    • Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: Identification of five sites of phosphorylation in vivo
    • Casamayor, A., N.A. Morrice, and D.R. Alessi. 1999. Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo. Biochem. J. 342:287-292.
    • (1999) Biochem. J , vol.342 , pp. 287-292
    • Casamayor, A.1    Morrice, N.A.2    Alessi, D.R.3
  • 10
    • 24944468632 scopus 로고    scopus 로고
    • Stable interaction between α5α1 integrin and Tie2 tyrosine kinase receptor regulates endothelial cell response to Ang-1
    • Cascone, I., L. Napione, F. Maniero, G. Serini, and F. Bussolino. 2005. Stable interaction between α5α1 integrin and Tie2 tyrosine kinase receptor regulates endothelial cell response to Ang-1. J. Cell Biol. 170:993-1004.
    • (2005) J. Cell Biol , vol.170 , pp. 993-1004
    • Cascone, I.1    Napione, L.2    Maniero, F.3    Serini, G.4    Bussolino, F.5
  • 11
    • 0007588936 scopus 로고    scopus 로고
    • Drosophila phosphoinositide-dependent kinase-1 regulates apoptosis and growth via the phosphoinositide 3-kinase-dependent signaling pathway
    • Cho, K.S., J.H. Lee, S. Kim, D. Kim, H. Koh, J. Lee, C. Kim, J. Kim, and J. Chung. 2001. Drosophila phosphoinositide-dependent kinase-1 regulates apoptosis and growth via the phosphoinositide 3-kinase-dependent signaling pathway. Proc. Natl. Acad. Sci. USA. 98:6144-6149.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 6144-6149
    • Cho, K.S.1    Lee, J.H.2    Kim, S.3    Kim, D.4    Koh, H.5    Lee, J.6    Kim, C.7    Kim, J.8    Chung, J.9
  • 12
    • 0035947085 scopus 로고    scopus 로고
    • Control of cell polarity and chemotaxis by Akt/PKB and PI3 kinase through the regulation of PAKa
    • Chung, C.Y., G. Potikyan, and R.A. Firtel. 2001. Control of cell polarity and chemotaxis by Akt/PKB and PI3 kinase through the regulation of PAKa. Mol. Cell. 7:937-947.
    • (2001) Mol. Cell , vol.7 , pp. 937-947
    • Chung, C.Y.1    Potikyan, G.2    Firtel, R.A.3
  • 13
    • 0042967831 scopus 로고    scopus 로고
    • In vivo role of the PIF-binding docking site of PDK1 defined by knock-in mutation
    • Collins, B.J., M. Deak, J.S. Arthur, L.J. Armit, and D.R. Alessi. 2003. In vivo role of the PIF-binding docking site of PDK1 defined by knock-in mutation. EMBO J. 22:4202-4211.
    • (2003) EMBO J , vol.22 , pp. 4202-4211
    • Collins, B.J.1    Deak, M.2    Arthur, J.S.3    Armit, L.J.4    Alessi, D.R.5
  • 14
    • 0037205266 scopus 로고    scopus 로고
    • PI 3-kinases and PTEN: How opposites chemoattract
    • Comer, F.I., and C.A. Parent. 2002. PI 3-kinases and PTEN: how opposites chemoattract. Cell. 109:541-544.
    • (2002) Cell , vol.109 , pp. 541-544
    • Comer, F.I.1    Parent, C.A.2
  • 15
    • 0033084143 scopus 로고    scopus 로고
    • Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1
    • Currie, R.A., K.S. Walker, A. Gray, M. Deak, A. Casamayor, C.P. Downes, P. Cohen, D.R. Alessi, and J. Lucocq. 1999. Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1. Biochem. J. 337:575-583.
    • (1999) Biochem. J , vol.337 , pp. 575-583
    • Currie, R.A.1    Walker, K.S.2    Gray, A.3    Deak, M.4    Casamayor, A.5    Downes, C.P.6    Cohen, P.7    Alessi, D.R.8    Lucocq, J.9
  • 16
    • 0041845305 scopus 로고    scopus 로고
    • Chemotactic cell movement during development
    • Dormann, D., and C.J. Weijer. 2003. Chemotactic cell movement during development. Curr. Opin. Genet. Dev. 13:358-364.
    • (2003) Curr. Opin. Genet. Dev , vol.13 , pp. 358-364
    • Dormann, D.1    Weijer, C.J.2
  • 17
    • 0037064020 scopus 로고    scopus 로고
    • Membrane localization of 3-phosphoinositide-dependent protein kinase-1 stimulates activities of Akt and atypical protein kinase C but does not stimulate glucose transport and glycogen synthesis in 3T3-L1 adipocytes
    • Egawa, K., H. Maegawa, K. Shi, T. Nakamura, T. Obata, T. Yoshizaki, K. Morino, S. Shimizu, Y. Nishio, E. Suzuki, and A. Kashiwagi. 2002. Membrane localization of 3-phosphoinositide-dependent protein kinase-1 stimulates activities of Akt and atypical protein kinase C but does not stimulate glucose transport and glycogen synthesis in 3T3-L1 adipocytes. J. Biol. Chem. 277:38863-38869.
    • (2002) J. Biol. Chem , vol.277 , pp. 38863-38869
    • Egawa, K.1    Maegawa, H.2    Shi, K.3    Nakamura, T.4    Obata, T.5    Yoshizaki, T.6    Morino, K.7    Shimizu, S.8    Nishio, Y.9    Suzuki, E.10    Kashiwagi, A.11
  • 18
    • 0033912843 scopus 로고    scopus 로고
    • Effect of phosphoinositide-dependent kinase 1 on protein kinase B translocation and its subsequent activation
    • Filippa, N., C.L. Sable, B.A. Hemmings, and E. Van Obberghen. 2000. Effect of phosphoinositide-dependent kinase 1 on protein kinase B translocation and its subsequent activation. Mol. Cell. Biol. 20:5712-5721.
    • (2000) Mol. Cell. Biol , vol.20 , pp. 5712-5721
    • Filippa, N.1    Sable, C.L.2    Hemmings, B.A.3    Van Obberghen, E.4
  • 19
    • 0034676303 scopus 로고    scopus 로고
    • Inhibition of PDK-1 activity causes a reduction in cell proliferation and survival
    • Flynn, P., M. Wongdagger, M. Zavar, N.M. Dean, and D. Stokoe. 2000. Inhibition of PDK-1 activity causes a reduction in cell proliferation and survival. Curr. Biol. 10:1439-1442.
    • (2000) Curr. Biol , vol.10 , pp. 1439-1442
    • Flynn, P.1    Wongdagger, M.2    Zavar, M.3    Dean, N.M.4    Stokoe, D.5
  • 20
    • 0037205265 scopus 로고    scopus 로고
    • Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis
    • Funamoto, S., R. Meili, S. Lee, L. Parry, and R.A. Firtel. 2002. Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis. Cell. 109:611-623.
    • (2002) Cell , vol.109 , pp. 611-623
    • Funamoto, S.1    Meili, R.2    Lee, S.3    Parry, L.4    Firtel, R.A.5
  • 21
    • 0033637929 scopus 로고    scopus 로고
    • The latent transforming growth factor-beta-binding protein-1 promotes in vitro differentiation of embryonic stem cells into endothelium
    • Gualandris, A., J.P. Annes, M. Arese, I. Noguera, V. Jurukovski, and D.B. Rifkin. 2000. The latent transforming growth factor-beta-binding protein-1 promotes in vitro differentiation of embryonic stem cells into endothelium. Mol. Biol. Cell. 11:4295-4308.
    • (2000) Mol. Biol. Cell , vol.11 , pp. 4295-4308
    • Gualandris, A.1    Annes, J.P.2    Arese, M.3    Noguera, I.4    Jurukovski, V.5    Rifkin, D.B.6
  • 22
    • 0034638836 scopus 로고    scopus 로고
    • Spatial sensing in fibroblasts mediated by 3′ phosphoinositides
    • Haugh, J.M., F. Codazzi, M. Teruel, and T. Meyer. 2000. Spatial sensing in fibroblasts mediated by 3′ phosphoinositides. J. Cell Biol. 151:1269-1280.
    • (2000) J. Cell Biol , vol.151 , pp. 1269-1280
    • Haugh, J.M.1    Codazzi, F.2    Teruel, M.3    Meyer, T.4
  • 23
    • 0037205230 scopus 로고    scopus 로고
    • Tumor suppressor PTEN mediates sensing of chemoattractant gradients
    • Iijima, M., and P. Devreotes. 2002. Tumor suppressor PTEN mediates sensing of chemoattractant gradients. Cell. 109:599-610.
    • (2002) Cell , vol.109 , pp. 599-610
    • Iijima, M.1    Devreotes, P.2
  • 24
    • 33749076673 scopus 로고    scopus 로고
    • SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity
    • Jacinto, E., V. Facchinetti, D. Liu, N. Soto, S. Wei, S.Y. Jung, Q. Huang, J. Qin, and B. Su. 2006. SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell. 127:125-137.
    • (2006) Cell , vol.127 , pp. 125-137
    • Jacinto, E.1    Facchinetti, V.2    Liu, D.3    Soto, N.4    Wei, S.5    Jung, S.Y.6    Huang, Q.7    Qin, J.8    Su, B.9
  • 25
    • 0033578776 scopus 로고    scopus 로고
    • 90-kDa ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1
    • Jensen, C.J., M.B. Buch, T.O. Krag, B.A. Hemmings, S. Gammeltoft, and M. Frodin. 1999. 90-kDa ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1. J. Biol. Chem. 274:27168-27176.
    • (1999) J. Biol. Chem , vol.274 , pp. 27168-27176
    • Jensen, C.J.1    Buch, M.B.2    Krag, T.O.3    Hemmings, B.A.4    Gammeltoft, S.5    Frodin, M.6
  • 26
    • 0033560707 scopus 로고    scopus 로고
    • Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2
    • Kobayashi, T., and P. Cohen. 1999. Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2. Biochem. J. 339:319-328.
    • (1999) Biochem. J , vol.339 , pp. 319-328
    • Kobayashi, T.1    Cohen, P.2
  • 28
    • 0030884103 scopus 로고    scopus 로고
    • PKB/Akt: Connecting phosphoinositide 3-kinase to cell survival and beyond
    • Marte, B.M., and J. Downward. 1997. PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond. Trends Biochem. Sci. 22:355-358.
    • (1997) Trends Biochem. Sci , vol.22 , pp. 355-358
    • Marte, B.M.1    Downward, J.2
  • 30
    • 0041327718 scopus 로고    scopus 로고
    • Leading the way: Directional sensing through phosphatidylinositol 3-kinase and other signaling pathways
    • Merlot, S., and R.A. Firtel. 2003. Leading the way: directional sensing through phosphatidylinositol 3-kinase and other signaling pathways. J. Cell Sci. 116:3471-3478.
    • (2003) J. Cell Sci , vol.116 , pp. 3471-3478
    • Merlot, S.1    Firtel, R.A.2
  • 33
    • 0034724736 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-stimulated actin reorganization and migration of endothelial cells is regulated via the serine/threonine kinase Akt
    • Morales-Ruiz, M., D. Fulton, G. Sowa, L.R. Languino, Y. Fujio, K. Walsh, and W.C. Sessa. 2000. Vascular endothelial growth factor-stimulated actin reorganization and migration of endothelial cells is regulated via the serine/threonine kinase Akt. Circ. Res. 86:892-896.
    • (2000) Circ. Res , vol.86 , pp. 892-896
    • Morales-Ruiz, M.1    Fulton, D.2    Sowa, G.3    Languino, L.R.4    Fujio, Y.5    Walsh, K.6    Sessa, W.C.7
  • 34
    • 0037337159 scopus 로고    scopus 로고
    • Regulation of the ABC kinases by phosphorylation: Protein kinase C as a paradigm
    • Newton, A.C. 2003. Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm. Biochem. J. 370:361-371.
    • (2003) Biochem. J , vol.370 , pp. 361-371
    • Newton, A.C.1
  • 36
    • 0002808369 scopus 로고
    • Morphogenetic mechanisms in avian vascular development
    • R.N. Feinberg, G.K. Sherer, and R. Auerbach, editors. S. Karger AG, Basel, Switzerland
    • Poole, T.J., and J.D. Coffin. 1991. Morphogenetic mechanisms in avian vascular development. In The Development of the Vascular System, vol. 14. R.N. Feinberg, G.K. Sherer, and R. Auerbach, editors. S. Karger AG, Basel, Switzerland. 25-36.
    • (1991) The Development of the Vascular System , vol.14 , pp. 25-36
    • Poole, T.J.1    Coffin, J.D.2
  • 37
    • 26444476029 scopus 로고    scopus 로고
    • Identification of CD36 molecular features required for its in vitro angiostatic activity
    • Primo, L., C. Ferrandi, C. Roca, S. Marchio, L. di Blasio, M. Alessio, and F. Bussolino. 2005. Identification of CD36 molecular features required for its in vitro angiostatic activity. FASEB J. 19:1713-1715.
    • (2005) FASEB J , vol.19 , pp. 1713-1715
    • Primo, L.1    Ferrandi, C.2    Roca, C.3    Marchio, S.4    di Blasio, L.5    Alessio, M.6    Bussolino, F.7
  • 39
    • 28544448768 scopus 로고    scopus 로고
    • Quantitative elucidation of a distinct spatial gradient-sensing mechanism in fibroblasts
    • Schneider, I.C., and J.M. Haugh. 2005. Quantitative elucidation of a distinct spatial gradient-sensing mechanism in fibroblasts. J. Cell Biol. 171:883-892.
    • (2005) J. Cell Biol , vol.171 , pp. 883-892
    • Schneider, I.C.1    Haugh, J.M.2
  • 40
    • 0034635513 scopus 로고    scopus 로고
    • Polarization of chemoattractant receptor signaling during neutrophil chemotaxis
    • Servant, G., O.D. Weiner, P. Herzmark, T. Balla, J.W. Sedat, and H.R. Bourne. 2000. Polarization of chemoattractant receptor signaling during neutrophil chemotaxis. Science. 287:1037-1040.
    • (2000) Science , vol.287 , pp. 1037-1040
    • Servant, G.1    Weiner, O.D.2    Herzmark, P.3    Balla, T.4    Sedat, J.W.5    Bourne, H.R.6
  • 41
    • 0037188941 scopus 로고    scopus 로고
    • Role of Akt signaling in vascular homeostasis and angiogenesis
    • Shiojima, I., and K. Walsh. 2002. Role of Akt signaling in vascular homeostasis and angiogenesis. Circ. Res. 90:1243-1250.
    • (2002) Circ. Res , vol.90 , pp. 1243-1250
    • Shiojima, I.1    Walsh, K.2
  • 43
    • 0036532121 scopus 로고    scopus 로고
    • Roles of PI3Ks in leukocyte chemotaxis and phagocytosis
    • Stephens, L., C. Ellson, and P. Hawkins. 2002. Roles of PI3Ks in leukocyte chemotaxis and phagocytosis. Curr. Opin. Cell Biol. 14:203-213.
    • (2002) Curr. Opin. Cell Biol , vol.14 , pp. 203-213
    • Stephens, L.1    Ellson, C.2    Hawkins, P.3
  • 45
    • 0037086609 scopus 로고    scopus 로고
    • PDK1 mediates growth factor-induced Ral-GEF activation by a kinase-independent mechanism
    • Tian, X., G. Rusanescu, W. Hou, B. Schaffhausen, and L.A. Feig. 2002. PDK1 mediates growth factor-induced Ral-GEF activation by a kinase-independent mechanism. EMBO J. 21:1327-1338.
    • (2002) EMBO J , vol.21 , pp. 1327-1338
    • Tian, X.1    Rusanescu, G.2    Hou, W.3    Schaffhausen, B.4    Feig, L.A.5
  • 46
    • 0034644523 scopus 로고    scopus 로고
    • Cellular signaling: Pivoting around PDK-1
    • Toker, A., and A.C. Newton. 2000. Cellular signaling: pivoting around PDK-1. Cell. 103:185-188.
    • (2000) Cell , vol.103 , pp. 185-188
    • Toker, A.1    Newton, A.C.2
  • 48
    • 0034653608 scopus 로고    scopus 로고
    • The PI3K-PDK1 connection: More than just a road to PKB
    • Vanhaesebroeck, B., and D.R. Alessi. 2000. The PI3K-PDK1 connection: more than just a road to PKB. Biochem. J. 346:561-576.
    • (2000) Biochem. J , vol.346 , pp. 561-576
    • Vanhaesebroeck, B.1    Alessi, D.R.2
  • 49
    • 0029998039 scopus 로고    scopus 로고
    • Embryonic stem cells differentiate in vitro to endothelial cells through successive maturation steps
    • Vittet, D., M.H. Prandini, R. Berthier, A. Schweitzer, H. Martin-Sisteron, G. Uzan, and E. Dejana. 1996. Embryonic stem cells differentiate in vitro to endothelial cells through successive maturation steps. Blood. 88:3424-3431.
    • (1996) Blood , vol.88 , pp. 3424-3431
    • Vittet, D.1    Prandini, M.H.2    Berthier, R.3    Schweitzer, A.4    Martin-Sisteron, H.5    Uzan, G.6    Dejana, E.7
  • 50
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-Kinase AKT pathway in human cancer
    • Vivanco, I., and C.L. Sawyers. 2002. The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat. Rev. Cancer. 2:489-501.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 51
    • 0035202090 scopus 로고    scopus 로고
    • Role of S6 phosphorylation and S6 kinase in cell growth
    • Volarevic, S., and G. Thomas. 2001. Role of S6 phosphorylation and S6 kinase in cell growth. Prog. Nucleic Acid Res. Mol. Biol. 65:101-127.
    • (2001) Prog. Nucleic Acid Res. Mol. Biol , vol.65 , pp. 101-127
    • Volarevic, S.1    Thomas, G.2
  • 52
    • 0034176579 scopus 로고    scopus 로고
    • The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells
    • Williams, M.R., J.S. Arthur, A. Balendran, J. van der Kaay, V. Poli, P. Cohen, and D.R. Alessi. 2000. The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells. Curr. Biol. 10:439-448.
    • (2000) Curr. Biol , vol.10 , pp. 439-448
    • Williams, M.R.1    Arthur, J.S.2    Balendran, A.3    van der Kaay, J.4    Poli, V.5    Cohen, P.6    Alessi, D.R.7
  • 53
    • 0043210428 scopus 로고    scopus 로고
    • Conditional suppression of cellular genes: Lentivirus vector-mediated drug-inducible RNA interference
    • Wiznerowicz, M., and D. Trono. 2003. Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference. J. Virol. 77:8957-8961.
    • (2003) J. Virol , vol.77 , pp. 8957-8961
    • Wiznerowicz, M.1    Trono, D.2


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