메뉴 건너뛰기




Volumn 83, Issue 4, 2007, Pages 474-484

DnIKK2-transfected dendritic cells induce a novel population of inducible nitric oxide synthase-expressing CD4+CD25- cells with tolerogenic properties

Author keywords

Dendritic cells; Inducible nitric oxide synthase; Rat kidney allotransplantation; T regulatory cells

Indexed keywords

ADENOVIRUS VECTOR; ALLOANTIGEN; GAMMA INTERFERON; I KAPPA B KINASE; I KAPPA B KINASE 2; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 2; NEUTRALIZING ANTIBODY; NITRIC OXIDE SYNTHASE INHIBITOR; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; IKK2 PROTEIN, RAT; INTERLEUKIN 2 RECEPTOR ALPHA;

EID: 33947538039     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.tp.0000251808.91901.c3     Document Type: Article
Times cited : (25)

References (47)
  • 1
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998; 392.
    • (1998) Nature , pp. 392
    • Banchereau, J.1    Steinman, R.M.2
  • 2
    • 0037039379 scopus 로고    scopus 로고
    • Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
    • Steinman RM, Nussenzweig MC. Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance. Proc Natl Acad Sci U S A 2002; 99: 351.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 351
    • Steinman, R.M.1    Nussenzweig, M.C.2
  • 3
    • 0037769110 scopus 로고    scopus 로고
    • Dendritic cells in immunity and tolerance-do they display opposite functions?
    • Moser M. Dendritic cells in immunity and tolerance-do they display opposite functions? Immunity 2003; 19: 5.
    • (2003) Immunity , vol.19 , pp. 5
    • Moser, M.1
  • 4
    • 0344984407 scopus 로고    scopus 로고
    • Dendritic cells: Regulators of alloimmunity and opportunities for tolerance induction
    • Morelli AE, Thomson AW. Dendritic cells: regulators of alloimmunity and opportunities for tolerance induction. Immunol Rev 2003; 196: 125.
    • (2003) Immunol Rev , vol.196 , pp. 125
    • Morelli, A.E.1    Thomson, A.W.2
  • 5
    • 0037987977 scopus 로고    scopus 로고
    • Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo
    • Wakkach A, Fournier N, Brun V, et al. Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo. Immunity 2003; 18: 605.
    • (2003) Immunity , vol.18 , pp. 605
    • Wakkach, A.1    Fournier, N.2    Brun, V.3
  • 6
    • 0029835032 scopus 로고    scopus 로고
    • -) prolong cardiac allograft survival in nonimmunosuppressed recipients
    • -) prolong cardiac allograft survival in nonimmunosuppressed recipients. Transplantation 1996; 62: 659.
    • (1996) Transplantation , vol.62 , pp. 659
    • Fu, F.1    Li, Y.2    Qian, S.3
  • 7
    • 0033939942 scopus 로고    scopus 로고
    • Immature dendritic cells generated with low doses of GM-CSF in the absence of IL-4 are maturation resistant and prolong allograft survival in vivo
    • Lutz MB, Suri RM, Niimi M, et al. Immature dendritic cells generated with low doses of GM-CSF in the absence of IL-4 are maturation resistant and prolong allograft survival in vivo. Eur J Immunol 2000; 30: 1813.
    • (2000) Eur J Immunol , vol.30 , pp. 1813
    • Lutz, M.B.1    Suri, R.M.2    Niimi, M.3
  • 8
    • 10744221193 scopus 로고    scopus 로고
    • Prolongation of skin graft survival by modulation of the alloimmune response with alternatively activated dendritic cells
    • Roelen DL, Schuurhuis DH, van den Boogaardt DE, et al. Prolongation of skin graft survival by modulation of the alloimmune response with alternatively activated dendritic cells. Transplantation 2003; 76: 1608.
    • (2003) Transplantation , vol.76 , pp. 1608
    • Roelen, D.L.1    Schuurhuis, D.H.2    van den Boogaardt, D.E.3
  • 9
    • 13144256708 scopus 로고    scopus 로고
    • Rapamycin-treated, alloantigen-pulsed host dendritic cells induced Ag-specific T cell regulation and prolong graft survival
    • Taner T, Hackstein H, Wang Z, et al. Rapamycin-treated, alloantigen-pulsed host dendritic cells induced Ag-specific T cell regulation and prolong graft survival. Am J Transpl 2005; 5: 228.
    • (2005) Am J Transpl , vol.5 , pp. 228
    • Taner, T.1    Hackstein, H.2    Wang, Z.3
  • 10
    • 0034613767 scopus 로고    scopus 로고
    • + T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
    • + T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J Exp Med 2000; 192: 1213.
    • (2000) J Exp Med , vol.192 , pp. 1213
    • Jonuleit, H.1    Schmitt, E.2    Schuler, G.3
  • 11
    • 0012391130 scopus 로고    scopus 로고
    • Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells
    • Sato K, Yamashita N, Baba M, Matsuyama T. Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells. Blood 2003; 101: 3581.
    • (2003) Blood , vol.101 , pp. 3581
    • Sato, K.1    Yamashita, N.2    Baba, M.3    Matsuyama, T.4
  • 12
    • 1642403899 scopus 로고    scopus 로고
    • Modified dendritic cells coexpressing self and allogeneic major histocompatibility complex molecules: An efficient way to induce indirect pathway regulation
    • Mirenda V, Berton I, Read J, et al. Modified dendritic cells coexpressing self and allogeneic major histocompatibility complex molecules: an efficient way to induce indirect pathway regulation. J Am Soc Nephrol 2004; 15: 987.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 987
    • Mirenda, V.1    Berton, I.2    Read, J.3
  • 13
    • 20444426900 scopus 로고    scopus 로고
    • Inhibition of NF-kB and oxidative pathway human dendritic cells by antioxidative vitamins generates regulatory T cells
    • Tan PH, Sagoo P, Chan C, et al. Inhibition of NF-kB and oxidative pathway human dendritic cells by antioxidative vitamins generates regulatory T cells. J Immunol 2005; 174: 7633.
    • (2005) J Immunol , vol.174 , pp. 7633
    • Tan, P.H.1    Sagoo, P.2    Chan, C.3
  • 14
    • 0035022325 scopus 로고    scopus 로고
    • Effective antigen presentation by dendritic cells is NF-kappa B dependent: Coordinate regulation of MHC, co-stimulatory molecules and cytokines
    • Yoshimura S, Bondeson J, Foxwell BM, et al. Effective antigen presentation by dendritic cells is NF-kappa B dependent: coordinate regulation of MHC, co-stimulatory molecules and cytokines. Int Immunol 2001; 13: 675.
    • (2001) Int Immunol , vol.13 , pp. 675
    • Yoshimura, S.1    Bondeson, J.2    Foxwell, B.M.3
  • 15
    • 84984763849 scopus 로고    scopus 로고
    • Prolongation of cardiac allograft survival using dendritic cells treated with NF-kB decoy oligodeoxyribonucleotides
    • Giannoukakis N, Bonham CA, Qian S, et al. Prolongation of cardiac allograft survival using dendritic cells treated with NF-kB decoy oligodeoxyribonucleotides. Mol Ther 2000; 1: 430.
    • (2000) Mol Ther , vol.1 , pp. 430
    • Giannoukakis, N.1    Bonham, C.A.2    Qian, S.3
  • 16
    • 0346505340 scopus 로고    scopus 로고
    • The IKK NF-kappa B system: A treasure trove for drug development
    • Karin M, Yamamoto Y, Wang QM. The IKK NF-kappa B system: a treasure trove for drug development. Nat Rev Drug Discov 2004; 3: 17.
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 17
    • Karin, M.1    Yamamoto, Y.2    Wang, Q.M.3
  • 17
    • 0037289728 scopus 로고    scopus 로고
    • Andreakos E, Smith C, Monaco C, et al. Ikappa B kinase 2 but not NF-kappa B-inducing kinase is essential for effective DC antigen presentation in the allogeneic mixed lymphocyte reaction. Blood 2003; 101: 983.
    • Andreakos E, Smith C, Monaco C, et al. Ikappa B kinase 2 but not NF-kappa B-inducing kinase is essential for effective DC antigen presentation in the allogeneic mixed lymphocyte reaction. Blood 2003; 101: 983.
  • 19
    • 0038205926 scopus 로고    scopus 로고
    • Add-on anti-TGF-beta antibody to ACE inhibitor arrests progressive diabetic nephropathy in the rat
    • Benigni A, Zoja C, Corna D, et al. Add-on anti-TGF-beta antibody to ACE inhibitor arrests progressive diabetic nephropathy in the rat. J Am Soc Nephrol 2003; 14: 1816.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1816
    • Benigni, A.1    Zoja, C.2    Corna, D.3
  • 20
    • 0024553650 scopus 로고
    • Monoclonal antibodies recognizing transforming growth factor-beta. Bioactivity neutralization and transforming growth factor beta 2 affinity purification
    • Dasch JR, Pace DR, Waegell W, et al. Monoclonal antibodies recognizing transforming growth factor-beta. Bioactivity neutralization and transforming growth factor beta 2 affinity purification. J Immunol 1989; 142: 1536.
    • (1989) J Immunol , vol.142 , pp. 1536
    • Dasch, J.R.1    Pace, D.R.2    Waegell, W.3
  • 21
    • 0031881534 scopus 로고    scopus 로고
    • Generation of large numbers of immature and mature dendritic cells from rat bone marrow cultures
    • Talmor M, Mirza A, Turley S, et al. Generation of large numbers of immature and mature dendritic cells from rat bone marrow cultures. Eur J Immunol 1998; 28: 811.
    • (1998) Eur J Immunol , vol.28 , pp. 811
    • Talmor, M.1    Mirza, A.2    Turley, S.3
  • 22
    • 20844452718 scopus 로고    scopus 로고
    • Pretransplant donor peripheral blood mononuclear cell infusion induces tranplantation tolerance by generating regulatory T cells
    • Cavinato R, Casiraghi F, Azzollini N, et al. Pretransplant donor peripheral blood mononuclear cell infusion induces tranplantation tolerance by generating regulatory T cells. Tranplantation 2005; 79: 1034.
    • (2005) Tranplantation , vol.79 , pp. 1034
    • Cavinato, R.1    Casiraghi, F.2    Azzollini, N.3
  • 23
    • 0035196189 scopus 로고    scopus 로고
    • Thymic microchimerism correlates with the outcome of tolerance-inducing protocols for solid organ transplantation
    • Noris M, Cugini D, Casiraghi F, et al. Thymic microchimerism correlates with the outcome of tolerance-inducing protocols for solid organ transplantation. J Am Soc Nephrol 2001; 12: 2815.
    • (2001) J Am Soc Nephrol , vol.12 , pp. 2815
    • Noris, M.1    Cugini, D.2    Casiraghi, F.3
  • 24
    • 0037364976 scopus 로고    scopus 로고
    • Regulatory T cells in transplantation tolerance
    • Wood KJ, Sakaguchi S. Regulatory T cells in transplantation tolerance. Nat Rev Immunol 2003; 3: 199.
    • (2003) Nat Rev Immunol , vol.3 , pp. 199
    • Wood, K.J.1    Sakaguchi, S.2
  • 25
    • 0034929751 scopus 로고    scopus 로고
    • Nitric oxide and T helper cell immunity
    • Van der Veen RC. Nitric oxide and T helper cell immunity. Int Immunopharmacol 2001; 1: 1491.
    • (2001) Int Immunopharmacol , vol.1 , pp. 1491
    • Van der Veen, R.C.1
  • 26
    • 4043052238 scopus 로고    scopus 로고
    • Regulatory T cells and mechanisms of immune system control
    • O'Garra A, Vieira P. Regulatory T cells and mechanisms of immune system control. Nat Med 2004; 10: 801.
    • (2004) Nat Med , vol.10 , pp. 801
    • O'Garra, A.1    Vieira, P.2
  • 31
    • 2942692039 scopus 로고    scopus 로고
    • + T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes
    • + T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes. J Exp Med 2004; 199: 1467.
    • (2004) J Exp Med , vol.199 , pp. 1467
    • Tarbell, K.V.1    Yamazaki, S.2    Olson, K.3
  • 32
    • 21144436219 scopus 로고    scopus 로고
    • - T cells by in vitro Foxp3 gene transfer, can induce transplantation tolerance
    • - T cells by in vitro Foxp3 gene transfer, can induce transplantation tolerance. Transplantation 2005; 79: 1308.
    • (2005) Transplantation , vol.79 , pp. 1308
    • Chai, J.G.1    Xue, S.A.P.2    Coe, D.3
  • 33
    • 0035806289 scopus 로고    scopus 로고
    • + suppressor T cells
    • + suppressor T cells. J Exp Med 2001; 193: F41.
    • (2001) J Exp Med , vol.193
    • Shevach, E.M.1
  • 34
    • 0034716925 scopus 로고    scopus 로고
    • T cells: Key controllers of immunologic self-tolerance
    • Sakaguchi S. Regulatory T cells: key controllers of immunologic self-tolerance. Cell 2000; 101: 455.
    • (2000) Cell , vol.101 , pp. 455
    • Regulatory, S.S.1
  • 36
    • 0035186416 scopus 로고    scopus 로고
    • Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells
    • Weiner HL. Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells. Immunol Rev 2001; 182: 207.
    • (2001) Immunol Rev , vol.182 , pp. 207
    • Weiner, H.L.1
  • 38
    • 0037307921 scopus 로고    scopus 로고
    • Inhibitory feedback loop between tolerogenic dendritic cells and regulatory T cells in transplant tolerance
    • Min WP, Zhou D, Ichim TE, et al. Inhibitory feedback loop between tolerogenic dendritic cells and regulatory T cells in transplant tolerance. J Immunol 2003; 170: 1304.
    • (2003) J Immunol , vol.170 , pp. 1304
    • Min, W.P.1    Zhou, D.2    Ichim, T.E.3
  • 39
    • 0036687184 scopus 로고    scopus 로고
    • Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokines
    • Bacchetta R, Sartirana C, Levings MK, et al. Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokines. Eur J Immunol 2002; 32: 2237.
    • (2002) Eur J Immunol , vol.32 , pp. 2237
    • Bacchetta, R.1    Sartirana, C.2    Levings, M.K.3
  • 40
    • 0034840167 scopus 로고    scopus 로고
    • An overview of regulatory T cells
    • Groux H. An overview of regulatory T cells. Microbes Infect 2001; 3: 883.
    • (2001) Microbes Infect , vol.3 , pp. 883
    • Groux, H.1
  • 41
    • 0030704726 scopus 로고    scopus 로고
    • + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
    • + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 1997; 389: 737.
    • (1997) Nature , vol.389 , pp. 737
    • Groux, H.1    O'Garra, A.2    Bigler, M.3
  • 42
    • 0037018104 scopus 로고    scopus 로고
    • + T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines
    • + T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J Exp Med 2002; 195: 603.
    • (2002) J Exp Med , vol.195 , pp. 603
    • Barrat, F.J.1    Cua, D.J.2    Boonstra, A.3
  • 43
    • 0037148511 scopus 로고    scopus 로고
    • Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulate interleukin 10 production by dendritic cells: A novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussis
    • McGuirk P, McCann C, Mills KH. Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulate interleukin 10 production by dendritic cells: a novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussis. J Exp Med 2002; 195: 221.
    • (2002) J Exp Med , vol.195 , pp. 221
    • McGuirk, P.1    McCann, C.2    Mills, K.H.3
  • 44
    • 0346366991 scopus 로고    scopus 로고
    • + cells that require antigen-specific activation for suppression
    • + cells that require antigen-specific activation for suppression. J Immunol 2003; 171: 6431.
    • (2003) J Immunol , vol.171 , pp. 6431
    • Koenen, H.J.1    Fasse, E.2    Joosten, I.3
  • 45
    • 0347895101 scopus 로고    scopus 로고
    • + cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype
    • + cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype. Nature 2003; 421: 388.
    • (2003) Nature , vol.421 , pp. 388
    • Kemper, C.1    Chan, A.C.2    Green, J.M.3
  • 46
    • 1542345551 scopus 로고    scopus 로고
    • Experimental autoimmune encephalomyelitis in mice with a targeted deletion on the inducible nitric oxide synthase gene: Increased T-helper 1 response
    • Kahl KG, Schmidt HH, Jung S, et al. Experimental autoimmune encephalomyelitis in mice with a targeted deletion on the inducible nitric oxide synthase gene: increased T-helper 1 response. Neurosci Lett 2004; 358: 58.
    • (2004) Neurosci Lett , vol.358 , pp. 58
    • Kahl, K.G.1    Schmidt, H.H.2    Jung, S.3
  • 47
    • 0031573608 scopus 로고    scopus 로고
    • Inhibition of inducible nitric oxide synthase intensifies injury and functional deterioration in autoimmune interstitial nephritis
    • Gabbai FB, Boggiano C, Peter T. Inhibition of inducible nitric oxide synthase intensifies injury and functional deterioration in autoimmune interstitial nephritis. J Immunol 1997; 159: 626.
    • (1997) J Immunol , vol.159 , pp. 626
    • Gabbai, F.B.1    Boggiano, C.2    Peter, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.