Generation or large numbers of immature and mature dendritic cells from rat bone marrow cultures

European Journal of Immunology

Volumn 28, Issue 3, 1998, Pages 811-817

  Talmor, Mia ^a   Mirza, Asra ^b   Turley, Shannon ^c   Mellman, Ira ^c   Hoffman, Lloyd A ^a   Steinman, Ralph M ^b  

^a WEILL CORNELL MEDICAL CENTER   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c YALE UNIVERSITY   (United States)

Author keywords

Bone marrow; Dendritic cells; Granulocyte macrophage colony stimulating factor; IL 4; Rat

Indexed keywords

CD34 ANTIGEN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 4; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BONE MARROW CULTURE; CELL MATURATION; CELL PROLIFERATION; DENDRITIC CELL; IMMUNOPHENOTYPING; LYSOSOME; NONHUMAN; PRIORITY JOURNAL; RAT; STEM CELL;

ANIMALS; ANTIGENS, SURFACE; BONE MARROW CELLS; CELL DIFFERENTIATION; DENDRITIC CELLS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HISTOCOMPATIBILITY ANTIGENS CLASS II; INTERLEUKIN-4; LYMPHOCYTE CULTURE TEST, MIXED; MICE; MICROSCOPY, CONFOCAL; RATS; RATS, INBRED ACI; RATS, INBRED STRAINS; SPLEEN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031881534     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199803)28:03<811::AID-IMMU811>3.0.CO;2-S     Document Type: Article

References (18)

1. Inaba, K., Steinman, R. M., Witmer-Pack, M., Aya, H., Inaba, M., Sudo, T., Wolpe, S. and Schuler, G., Identification of proliferating dendritic cell precursors in mouse blood. J. Exp. Med. 1992. 175: 1157-1167.
2. Inaba, K., Inaba, M., Romani, N., Aya, H., Deguchi, M., Ikehara, S., Muramatsu, S. and Steinman, R. M., Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte-macrophage colony stimulating factors. J. Exp. Med. 1992. 176: 1693-1702.
3. Reid, C. D. L., Stackpoole, A., Meager, A. and Tikerpae, J., Interactions of tumor necrosis factor with granulocyte-macrophage colony-stimulating factor and other cytokines in the regulation of dendritic cell growth in vitro from early bipotent CD34 progenitors in human bone marrow. J. Immunol. 1992. 149: 2681-2688.
4. Caux, D., Dezutter-Dambuyant, C., Schmitt, D. and Banchereau, T., GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells. Nature 1992. 360: 258-261.
5. Sallusto, F. and Lanzavecchia, A., Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and down-regulated by tumor necrosis factor-α. J. Exp. Med. 1994. 179: 1109-1118.
6. Romani, N. S., Gruner, S., Brang, D., Kampgen, E., Lenz, A., Trockenbacher, B., Konwalinka, G., Fritsch, P. O., Steinman, R. M. and Schuler, G., Proliferating dendritic cell progenitors in human blood. J. Exp. Med. 1994. 180: 83-93.
7. Szabolcs, P., Moore, M. A. S. and Young, J. W., Expansion of immunostimulatory dendritic cells among the myeloid progeny of human CD34 + bone marrow precursors cultured with c-kit ligand, granulocyte-macrophage colony-stimulating factor, and TNFα. J. Immunol. 1995. 154: 5851-5861.
8. Bowers, W. E. and Berkowitz, M. R., Differentiation of dendritic cells in cultures of rat bone marrow cells. J. Exp. Med. 1986. 163: 872-883.
9. Chen-Woan, M., Delaney, C. P., Fournier, V., Wakizaka, Y., Murase, N., Fung, J., Starzl, T. E. and Demetris, A. J., A new protocol for the propagation of dendritic cells from rat bone marrow using recombinant GM-CSF, and their quantification using the mAb OX-62. J. Immunol. Methods 1995. 178: 157-171.
10. Moore, M. A. S., The clinical use of colony stimulating factors. Annu. Rev. Immunol. 1991. 9: 159-191.
11. Jansen, J. H., Wientjens, G. J. H. M., Fibbe, W. E., Willemze, R. and Kluin-Nelemans, H. C., Inhibition of human macrophage colony formation by interleukin 4. J. Exp. Med. 1989. 170: 577-582.
12. Klinkert, W. E. F., LaBadie, J. H. and Bowers, W. E., Accessory and stimulating properties of dendritic cells and macrophages isolated from various rat tissues. J. Exp. Med. 1982. 156: 1-19.
13. MacPherson, G. G., Properties of lymph-borne [veiled] dendritic cells in culture. I. Modulation of phenotype, survival and function: partial dependence on GM-CSF. Immunology 1989. 68: 102-107.
14. Sallusto, F. and Lanzavecchia, A., Dendritic cells use macrophinocytosis and the mannose receptor to concentrate antigen in the MHC class II compartment. Downregulation by cytokines and bacterial products. J. Exp. Med. 1995. 182: 389-400.
15. Pierre, P., Turley, S. J., Gatti, E., Hull, M., Meltzer, J., Mirza, A., Inaba, K., Steinman, R. M. and Mellman, I., Developmental regulation of MHC class II compartments and transport in mouse dendritic cells. Nature 1997. 388: 787-792.
16. Romani, N., Koide, S., Crowley, M., Witmer-Pack, M., Livingstone, A. M., Fathman, C. G., Inaba, K. and Steinman, R. M., Presentation of exogenous protein antigens by dendritic cells to T cell clones: intact protein is presented best by immature, epidermal Langerhans cells. J. Exp. Med. 1989. 169: 1169-1178.
17. Pierre, P., Denzin, L. K., Hammond, C., Drake, J. R., Amigorena, S., Cresswell, P. and Mellman, I., HLA-DM is expressed in conventional and unconventional MHC class II-containing compartments. Immunity 1996. 4: 229-239.
18. Lewis, V., Green, S. and Marsh, M., Glycoproteins of the lysosomal membrane. J. Cell Biol. 1985. 100: 1839-1849