Oligonucleotides suppress IL-8 in skin keratinocytes in vitro and offer anti-inflammatory properties in vivo

Journal of Investigative Dermatology

Volumn 127, Issue 4, 2007, Pages 846-854

  Dorn, Annette ^a,b   Ludwig, Ralf Joachim ^a   Bock, Andreas ^b   Thaci, Diamant ^a   Hardt, Katja ^a   Bereiter Hahn, Jurgen ^a   Kaufmann, Roland ^a   Bernd, August ^a   Kippenberger, Stefan ^a  

^a GOETHE UNIVERSITY   (Germany)

^b Phenion GmbH and Co   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CPG 1 PHOSPHOROTHIOATE OLIGODEOXYNUCLEOTIDE; CPG 9 PHOSPHOROTHIOATE OLIGODEOXYNUCLEOTIDE; CPG OLIGODEOXYNUCLEOTIDE; INTERLEUKIN 8; LACTATE DEHYDROGENASE; NON CPG 5 PHOSPHOROTHIOATE OLIGODEOXYNUCLEOTIDE; NON CPG 5G PHOSPHOROTHIOATE OLIGODEOXYNUCLEOTIDE; OLIGODEOXYNUCLEOTIDE DERIVATIVE; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; PLACEBO; POLYCYTIDYLIC ACID; PREDNICARBATE; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BIOACCUMULATION; CELL CULTURE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTACT ALLERGY; CONTROLLED STUDY; CYTOKINE RELEASE; DELETION MUTANT; DRUG UPTAKE; FLUORESCENCE ANALYSIS; HUMAN; HUMAN CELL; IMMUNOLOGY; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SPACE; KERATINOCYTE; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN INDUCTION; SKIN CELL; SKIN SENSITIZATION; SUPERNATANT;

ADMINISTRATION, TOPICAL; ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; COMPUTER SYSTEMS; CPG ISLANDS; DERMATITIS, CONTACT; DNA; DNA METHYLATION; EAR, EXTERNAL; GENES, DOMINANT; HUMANS; HYPERSENSITIVITY, DELAYED; INTERLEUKIN-8; KERATINOCYTES; L-LACTATE DEHYDROGENASE; MALE; MICE; MICE, INBRED C57BL; MYELOID DIFFERENTIATION FACTOR 88; OLIGODEOXYRIBONUCLEOTIDES; POLYMERASE CHAIN REACTION; TOLL-LIKE RECEPTOR 9; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 33947222665     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/sj.jid.5700620     Document Type: Article

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