Responses of the rat olfactory epithelium to retronasal air flow

Journal of Neurophysiology

Volumn 97, Issue 3, 2007, Pages 1941-1950

  Scott, John W ^a   Acevedo, Humberto P ^a   Sherrill, Lisa ^a   Phan, Maggie ^b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; HYDROPHILICITY; HYDROPHOBICITY; NONHUMAN; NOSE AIRFLOW; OLFACTOMETRY; OLFACTORY BULB; OLFACTORY EPITHELIUM; PRIORITY JOURNAL; RAT; SMELLING; SOLUBILITY;

ACTION POTENTIALS; ANIMALS; HUMIDITY; MALE; MOUTH; NASAL CAVITY; ODORS; OLFACTORY MUCOSA; RATS; RATS, SPRAGUE-DAWLEY; SMELL; STIMULATION, CHEMICAL;

EID: 33947173149     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.01305.2006     Document Type: Article

References (38)

1. Aungst JL, Heyward PM, Puche AC, Karnup SV, Hayar A, Szabo G, Shipley MT. Centre-surround inhibition among olfactory bulb glomeruli. Nature 426: 623-629, 2003.
2. Bouton ME, Jones DL, McPhillips SA, Swartzentruber D. Potentiation and overshadowing in odor-aversion learning: role of method of odor presentation, the distal-proximal cue distinction, and the conditionability of odor. Learn Motiv 17: 115-138, 1986.
3. Burdach KJ, Doty RL. The effects of mouth movements, swallowing, and spitting on retronasal odor perception. Physiol Behav 41: 353-356, 1987.
4. Burke J. Solubility parameters: theory and application. In: The Book and Paper Group Annual, edited by Jensen C. Ann Arbor, MI: The American Institute for Conservation, 1984, p. 13-58.
5. Diaz ME. Comparison between orthonasal and retronasal flavour perception at different concentrations. Flavour Fragr J 19: 499-504, 2004.
6. Frasnelli J, Heilmann S, Hummel T. Responsiveness of human nasal mucosa to trigeminal stimuli depends on the site of stimulation. Neurosci Lett 362: 65-69, 2004.
7. Frasnelli J, van Ruth S, Kriukova I, Hummel T. Intranasal concentrations of orally administered flavors. Chem Senses 30: 575-582, 2005.
8. Hajjar E, Perahia D, Debat H, Nespoulous C, Robert CH. Odorant binding and conformational dynamics in the odorant-binding protein. J Biol Chem 281: 29929-29937, 2006.
9. Hansen CM. Hansen Solubility Parameters: A User's Handbook. Boca Raton, FL: CRC Press, 1999.
10. Heilmann S, Hummel T. A new method for comparing orthonasal and retronasal olfaction. Behav Neurosci 118: 412-419, 2004.
11. Ho SL, Johnson BA, Chen AL, Leon M. Differential responses to branched and unsaturated aliphatic hydrocarbons in the rat olfactory system. J Comp Neurol 499: 519-532, 2006b.
12. Ho SL, Johnson BA, Leon M. Long hydrocarbon chains serve as unique molecular features recognized by ventral glomeruli of the rat olfactory bulb. J Comp Neurol 498: 16-30, 2006a.
13. Hodgson M, Linforth RS, Taylor AJ. Simultaneous real-time measurements of mastication, swallowing, nasal airflow, and aroma release. J Agric Food Chem 51: 5052-5057, 2003.
14. Imamura K, Mataga N, Mori K. Coding of odor molecules by mitral/tufted cells in rabbit olfactory bulb. I. Aliphatic compounds. J Neurophysiol 68: 1986-2002, 1992.
15. Inui T, Shimura T, Yamamoto T. Effects of brain lesions on taste-potentiated odor aversion in rats. Behav Neurosci 120: 590-599, 2006.
16. Leclerc S, Heydel JM, Amosse V, Gradinaru D, Cattarelli M, Artur Y, Goudonnet H, Magdalou J, Netter P, Pelczar H, Minn A. Glucuronidation of odorant molecules in the rat olfactory system: activity, expression and age-linked modifications of UDP-glucuronosyltransferase isoforms, UGT1A6 and UGT2A1, and relation to mitral cell activity. Brain Res Mol Brain Res 107: 201-213, 2002.
17. Lobel D, Jacob M, Volkner M, Breer H. Odorants of different chemical classes interact with distinct odorant binding protein subtypes. Chem Senses 27: 39-44, 2002.
18. Mestres M, Moran N, Jordan A, Buettner A. Aroma release and retronasal perception during and after consumption of flavored whey protein gels with different textures. 1. In vivo release analysis. J Agric Food Chem 53: 403-409, 2005.
19. Mozell MM, Jagodowicz M. Chromatographic separation of odorants by the nose: retention times measured across in vivo olfactory mucosa. Science 181: 1247-1249, 1973.
20. Mozell MM, Kent PF, Murphy SJ. The effects of flow-rate upon the magnitude of the olfactory response differs for different odorants. Chem Senses 16: 631-649, 1991.
21. Mozell MM, Sheehe PR, Hornung DE, Kent PF, Youngentob SL, Murphy SJ. "Imposed" and "inherent" mucosal activity patterns. Their composite representation of olfactory stimuli. J Gen Physiol 90: 625-650, 1987.
22. Murphy C, Cain WS. Taste and olfaction: independence vs interaction. Physiol Behav 24: 601-605, 1980.
23. Murphy C, Cain WS, Bartoshuk LM. Mutual action of taste and olfaction. Sens Process 1: 204-211, 1977.
24. Pierce J, Halpern BP. Orthonasal and retronasal odorant identification based upon vapor phase input from common substances. Chem Senses 21: 529-543, 1996.
25. Rozin P. "Taste-smell confusions" and the duality of the olfactory sense. Percept Psychophys 31: 397-401, 1982.
26. Scott JW. Sniffing and spatiotemporal coding in olfaction. Chem Senses 31: 119-130, 2006.
27. Scott JW, Acevedo HP, Sherrill L. Effects of concentration and sniff flow rate on the rat electroolfactogram. Chem Senses 31: 581-593, 2006.
28. Scott JW, Brierley T. A functional map in rat olfactory epithelium. Chem Senses 24: 679-690, 1999.
29. Scott JW, Brierley T, Schmidt FH. Chemical determinants of the rat electro-olfactogram. J Neurosci 20: 4721-4731, 2000.
30. Scott JW, Davis LM, Shannon D, Kaplan C. Relation of chemical structure to spatial distribution of sensory responses in rat olfactory epithelium. J Neurophysiol 75: 2036-2049, 1996.
31. Scott-Johnson PE, Blakley D, Scott JW. Effects of air flow on rat electroolfactogram. Chem Senses 25: 761-768, 2000.
32. Slotnick BM, Westbrook F, Darling FMC. What the rat's nose tells the rat's mouth: long delay aversion conditioning with aqueous odors and potentiation of taste by odors. Anim Learn Behav 25: 357-369, 1997.
33. Small DM, Gerber JC, Mak YE, Hummel T. Differential neural responses evoked by orthonasal versus retronasal odorant perception in humans. Neuron 47: 593-605, 2005.
34. Sobel N, Prabhakaran V, Desmond JE, Glover GH, Goode RL, Sullivan EV, Gabrieli JD. Sniffing and smelling: separate subsystems in the human olfactory cortex. Nature 392: 282-286, 1998.
35. Sun BC, Halpern BP. Identification of air phase retronasal and orthonasal odorant pairs. Chem Senses 30: 693-706, 2005.
36. Takahashi YK, Kurosaki M, Hirono S, Mori K. Topographic representation of odorant molecular features in the rat olfactory bulb. J Neurophysiol 92: 2413-2427, 2004.
37. Zhao K, Dalton P, Yang GC, Scherer PW. Numerical modeling of turbulent and laminar airflow and odorant transport during sniffing in the human and rat nose. Chem Senses 31: 107-118, 2006.
38. Zhao K, Scherer PW, Hajiloo SA, Dalton P. Effect of anatomy on human nasal air flow and odorant transport patterns: implications for olfaction. Chem Senses 29: 365-379, 2004.