Effects of brain lesions on taste-potentiated odor aversion in rats

Behavioral Neuroscience

Volumn 120, Issue 3, 2006, Pages 590-599

  Inui, Tadashi ^a   Shimura, Tsuyoshi ^a   Yamamoto, Takashi ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

Amygdala; Insular cortex; Lesion; Parvicellular part of ventroposteromedial thalamic nucleus; Taste potentiated odor aversion

Indexed keywords

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN DAMAGE; CONTROLLED STUDY; CORRELATION ANALYSIS; EXPERIMENTAL RAT; INSULA; MALE; NONHUMAN; ODOR; OLFACTORY DISCRIMINATION; OLFACTORY SYSTEM; RAT; STIMULUS; TASTE; TASTE AVERSION; TASTE DISORDER; THALAMUS VENTRAL NUCLEUS;

AMYGDALA; ANALYSIS OF VARIANCE; ANIMALS; AVOIDANCE LEARNING; BRAIN INJURIES; CONDITIONING, CLASSICAL; DRINKING; DRINKING BEHAVIOR; MALE; ODORS; RATS; RATS, WISTAR; SACCHARIN; SMELL; TASTE;

EID: 33745913058     PISSN: 07357044     EISSN: None     Source Type: Journal    
DOI: 10.1037/0735-7044.120.3.590     Document Type: Article

References (49)

1. Aggleton, J. P., Petrides, M., & Iversen, S. D. (1981). Differential effects of amygdaloid lesions on conditioned taste aversion learning by rats. Physiology & Behavior, 27, 397-400.
2. Azuma, S., Yamamoto, T., & Kawamura, Y. (1984). Studies on gustatory responses of amygdaloid neurons in rats. Experimental Brain Research, 56, 12-22.
3. Bermudez-Rattoni, F., Grijalva, C. V., Kiefer, S. W., & Garcia, J. (1986). Flavor-illness aversions: The role of the amygdala in the acquisition of taste-potentiated odor aversions. Physiology & Behavior, 38, 503-508.
4. Bermudez-Rattoni, F., & McGaugh, J. L. (1991). Insular cortex and amygdala lesions differentially affect acquisition of inhibitory avoidance and conditioned taste aversion. Brain Research, 549, 165-170.
5. Bermudez-Rattoni, F., Rusiniak, K. W., & Garcia, J. (1983). Flavor-illness aversions: Potentiation of odor by taste is disrupted by application of novocaine into the amygdala. Behavioral Neural Biology, 37, 61-75.
6. Borsini, F., & Rolls, E. T. (1984). Role of noradrenaline and serotonin in the basolateral region of the amygdala in food preferences and learned taste aversions in the rat. Physiology & Behavior, 33, 37-43.
7. Bouton, M. E., Jones, D. L., McPhillips, S. A., & Swartzentruber, D. (1986). Potentiation and overshadowing in odor-aversion learning: Role of method of odor presentation, the distal-proximal cue distinction, and the conditionability of odor. Learning & Motivation, 17, 115-138.
8. Burdach, K. J., & Doty, R. L. (1987). The effects of mouth movements, swallowing, and spitting on retronasal odor perception. Physiology & Behavior, 41, 353-356.
9. Cechetto, D. F., & Saper, C. B. (1987). Evidence for a viscerotopic sensory representation in the cortex and thalamus in the rat. Journal of Comparative Neurology, 262, 27-45.
10. Cubero, I., Thiele, T. E., & Bernstein, I. L. (1999). Insular cortex lesions and taste aversion learning: Effects of conditioning method and timing of lesion. Brain Research, 839, 323-330.
11. Davies, J. (1980). Embryology and anatomy of the head, neck, face, palate, nose and paranasal sinuses. In M. M. Paparella & D. A. Shumrick (Eds.), Otolaryngology: Vol. 1. Basic sciences and related disciplines (2nd ed., pp. 63-131). Philadelphia: Saunders.
12. Dunn, L. T., & Everitt, B. J. (1988). Double dissociations of the effects of amygdala and insular cortex lesions on conditioned taste aversion, passive avoidance, and neophobia in the rat using the excitotoxin ibotenic acid. Behavioral Neuroscience, 102, 3-23.
13. Fernandez-Ruiz, J., Miranda, M. I., Bermudez-Rattoni, F., & Drucker-Colin, R. (1993). Effects of catecholaminergic depletion of the amygdala and insular cortex on the potentiation of odor by taste aversions. Behavioral Neural Biology, 60, 189-191.
14. Ferry, B., Sandner, G., & Di Scala, G. (1995). Neuroanatomical and functional specificity of the basolateral amygdaloid nucleus in taste-potentiated odor aversion. Neurobiology of Learning & Memory, 64, 169-180.
15. Flynn, F. W., Schulkin, J., Grill, H. J., & Norgren, R. (1991). Central Gustatory lesions: II. Effects on sodium appetite, taste aversion learning, and feeding behaviors. Behavioral Neuroscience, 105, 944-954.
16. Giachetti, I., & MacLeod, P. (1977). Olfactory input to the thalamus: Evidence for a ventroposteromedial projection. Brain Research, 125, 166-169.
17. Grigson, P. S., Lyuboslavsky, P. N., & Tanase, D. (2000). Bilateral lesions of the gustatory thalamus disrupt morphine - but not Li-induced intake suppression in rats: Evidence against conditioned taste aversion hypothesis. Brain Research, 858, 327-337.
18. Hatfield, T., & Gallagher, M. (1995). Taste-potentiated odor conditioning: Impairment produced by infusion of an N-methyl-D-aspartate antagonist into basolateral amygdala. Behavioral Neuroscience, 109, 663-668.
19. Hatfield, T., Graham, P. W., & Gallagher, M. (1992). Taste-potentiated odor aversion learning: Role of the amygdaloid basolateral complex and central nucleus. Behavioral Neuroscience, 106, 286-293.
20. Kiefer, S. W., Cabral, R. J., & Garcia, J. (1984). Neonatal ablations of the gustatory neocortex in the rat: Taste aversion learning and taste reactivity. Behavioral Neuroscience, 98, 804-812.
21. Kiefer, S. W., & Orr, M. R. (1992). Taste avoidance, but not aversion, learning in rats lacking gustatory cortex. Behavioral Neuroscience, 106, 140-146.
22. Kiefer, S. W., Rusiniak, K. W., & Garcia, J. (1982). Flavor-illness aversions: Gustatory neocortex ablations disrupt taste but not taste-potentiated odor cues. Journal of Comparative and Physiological Psychology, 96, 540-548.
23. Lasiter, P. S. (1982). Cortical substrates of taste aversion learning: Direct amygdalocortical projections to the gustatory neocortex do not mediate conditioned aversion learning. Physiological Psychology, 10, 377-383.
24. Lasiter, P. S., Deems, D. A., & Garcia, J. (1985). Involvement of the anterior insular gustatory neocortex in taste-potentiated odor aversion learning. Physiology and Behavior, 34, 71-77.
25. Lasiter, P. S., & Glanzman, D. L. (1985). Cortical substrates of taste aversion learning: Involvement of dorsolateral amygdaloid nuclei and temporal neocortex in taste aversion learning. Behavioral Neuroscience, 99, 257-276.
26. Loullis, C. C., Wayner, M. J., & Jolicoeur, F. B. (1978). Thalamic taste nuclei lesions and taste aversions. Physiology & Behavior, 20, 653-655.
27. Lundy, F. R., Jr., & Norgren, R. (2004). Gustatory system. In G. Paxinos, & J. Mai (Eds.), The rat nervous system (3rd ed., pp. 891-921). San Diego: Academic Press.
28. Mikulka, P. J., Freeman, F. G., & Lidstrom, P. (1977). The effect of training technique and amygdala lesions on the acquisition and retention of a taste aversion. Behavioral Biology, 19, 509-517.
29. Nachman, M., & Ashe, J. H. (1974). Effects of basolateral amygdala lesions on neophobia, learned taste aversions, and sodium appetite in rats. Journal of Comparative and Physiological Psychology, 87, 622-643.
30. Nakashima, M., Uemura, M., Yasui, K., Ozaki, H. S., Tabata, S., & Taen, A. (2000). An anterograde and retrograde tract-tracing study on the projections from the thalamic gustatory area in the rat: Distribution of neurons projecting to the insular cortex and amygdaloid complex. Neuroscience Research, 36, 297-309.
31. Norgren, R. (1976). Taste pathways to hypothalamus and amygdala. Journal of Comparative Neurology, 166, 17-30.
32. Ottersen, O. P. (1982). Connections of the amygdala of the rat: IV. Corticoamygdaloid and intraamygdaloid connections as studied with axonal transport of horseradish peroxidase. Journal of Comparative Neurology, 205, 30-48.
33. Palmerino, C. C., Rusiniak, K. W., & Garcia, J. (1980, May 16). Flavor-illness aversions: The peculiar roles of odor and taste in memory for poison. Science, 208, 753-755.
34. Paxinos, G., & Watson, C. (1998). The rat brain in stereotaxic coordinates (4th ed.). San Diego: Academic Press.
35. Reilly, S., Bornovalova, M., Dengler, C., & Trifunovic, R. (2003). Effects of excitotoxic lesions of the gustatory thalamus on latent inhibition and blocking of conditioned taste aversion in rats. Brain Research Bulletin, 62, 117-128.
36. Roberts, D. D., & Acree, T. E. (1995). Simulation of retronasal aroma using a modified headspace technique: Investigating the effects of saliva, temperature, shearing and oil on flavor release. Journal of Agricultural and Food Chemists, 43, 2179-2186.
37. Rusiniak, K. W., Hankins, W. G., Garcia, J., & Brett, L. P. (1979). Flavor-illness aversions: Potentiation of odor by taste in rats. Behavioral Neural Biology, 25, 1-17.
38. Saper, C. B. (1982). Convergence of autonomic and limbic connections in the insular cortex of the rat. Journal of Comparative Neurology, 210, 163-173.
39. Saper, C. B., & Loewy, A. D. (1980). Efferent connections of the parabrachial nucleus in the rat. Brain Research, 197, 291-317.
40. Scalera, G., Grigson, P. S., & Norgren, R. (1997). Gustatory functions, sodium appetite, and conditioned taste aversion survive excitotoxic lesions of the thalamic taste area. Behavioral Neuroscience, 111, 633-645.
41. Shipley, M. T., McLean, J. H., & Ennis, M. (1995). Olfactory system. In G. Paxinos (Ed.), The rat nervous system (pp. 899-926). San Diego: Academic Press.
42. Simbayi, L. C., Boakes, R. A., & Burton, M. J. (1986). Effects of basolateral amygdala lesions on taste aversions produced by lactose and lithium chloride in the rat. Behavioral Neuroscience, 100, 455-465.
43. Slotnick, B. M., Westbrook, F., & Darling, F. M. (1997). What the rat's nose tells the rat's mouth: Long delay aversion conditioning with aqueous odors and potentiation of taste by odors. Animal Learning & Behavior, 25, 357-369.
44. Turner, B. H., & Herkenham, M. (1991). Thalamoamygdaloid projections in the rat: A test of the amygdala's role in sensory processing. Journal of Comparative Neurology, 313, 295-325.
45. Uwano, T., Nishijo, H., Ono, T., & Tamura, R. (1995). Neuronal responsiveness to various sensory stimuli, and associative learning in the rat amygdala. Neuroscience, 68, 339-361.
46. Voirol, E., & Daget, N. (1986). Comparative study of nasal and retronasal olfactory perception. Food Science and Technology, 19, 316-319.
47. Yamamoto, T., Azuma, S., & Kawamura, Y. (1984). Functional relations between the cortical gustatory area and the amygdala: Electrophysiological and behavioral studies in rats. Experimental Brain Research, 56, 23-31.
48. Yamamoto, T., & Fujimoto, Y. (1991). Brain mechanisms of taste aversion learning in the rat. Brain Research Bulletin, 27, 403-406.
49. Yamamoto, T., Fujimoto, Y., Shimura, T., & Sakai, N. (1995). Conditioned taste aversion in rats with excitotoxic brain lesions. Neuroscience Research, 22, 31-49.