메뉴 건너뛰기




Volumn 31, Issue 2, 2006, Pages 107-118

Numerical modeling of turbulent and laminar airflow and odorant transport during sniffing in the human and rat nose

Author keywords

Laminar nasal airflow; Odorant uptake modeling during sniff; Olfactory odorant uptake; Turbulent nasal airflow

Indexed keywords

ADULT; ARTICLE; BIOLOGICAL MODEL; COMPUTATIONAL FLUID DYNAMICS; EXHALATION; FEMALE; FLOW RATE; HUMAN; INHALATION; LAMINAR AIRFLOW; NONHUMAN; NOSE CAVITY; NOSE MUCOSA; OLFACTORY DISCRIMINATION; OLFACTORY RECEPTOR; OLFACTORY SYSTEM; PRIORITY JOURNAL; RAT; SIMULATION; SNIFFING; TURBULENT FLOW;

EID: 32544453395     PISSN: 0379864X     EISSN: None     Source Type: Journal    
DOI: 10.1093/chemse/bjj008     Document Type: Article
Times cited : (155)

References (28)
  • 1
    • 0020595053 scopus 로고
    • Experimental study of velocity fields in a human nasal fossa by laser anemometry
    • Girardin, M., Bilgen, E. and Arbour, P. (1983) Experimental study of velocity fields in a human nasal fossa by laser anemometry. Ann. Otol. Rhinol. Laryngol., 92, 231-236.
    • (1983) Ann. Otol. Rhinol. Laryngol. , vol.92 , pp. 231-236
    • Girardin, M.1    Bilgen, E.2    Arbour, P.3
  • 2
    • 0027487191 scopus 로고
    • Velocity profiles measured for airflow through a large-scale model of the human nasal cavity
    • Hahn, I., Scherer, P.W. and Mozell, M.M. (1993) Velocity profiles measured for airflow through a large-scale model of the human nasal cavity. J. Appl. Physiol., 75, 2273-2287.
    • (1993) J. Appl. Physiol. , vol.75 , pp. 2273-2287
    • Hahn, I.1    Scherer, P.W.2    Mozell, M.M.3
  • 3
    • 0002428430 scopus 로고
    • Absorption of soluble gases and vapors in the respiratory system
    • Chang, H.K. and Paiva, M. (eds), Marcel Dekker Inc., New York
    • Hanna, L.M., Frank, R. and Scherer, P.W. (1989) Absorption of soluble gases and vapors in the respiratory system. In Chang, H.K. and Paiva, M. (eds), Respiratory Physiology. Marcel Dekker Inc., New York, pp. 277-316.
    • (1989) Respiratory Physiology , pp. 277-316
    • Hanna, L.M.1    Frank, R.2    Scherer, P.W.3
  • 4
    • 0022671946 scopus 로고
    • Measurement of local mass transfer coefficients in a cast model of the human upper respiratory tract
    • Hanna, L.M. and Scherer, P.W. (1986) Measurement of local mass transfer coefficients in a cast model of the human upper respiratory tract. J. Biomech. Eng., 108, 12-18.
    • (1986) J. Biomech. Eng. , vol.108 , pp. 12-18
    • Hanna, L.M.1    Scherer, P.W.2
  • 6
    • 0033927852 scopus 로고    scopus 로고
    • Detailed flow patterns in the nasal cavity
    • Kelly, J.T., Prasad, A.K. and Wexler, A.S. (2000) Detailed flow patterns in the nasal cavity. J. Appl. Physiol., 89, 323-337.
    • (2000) J. Appl. Physiol. , vol.89 , pp. 323-337
    • Kelly, J.T.1    Prasad, A.K.2    Wexler, A.S.3
  • 7
    • 0030061751 scopus 로고    scopus 로고
    • The interaction of imposed and inherent olfactory mucosal activity patterns and their composite representation in a mammalian species using voltage-sensitive dyes
    • Kent, P.F., Mozell, M.M., Murphy, S.J. and Hornung, D.E. (1996) The interaction of imposed and inherent olfactory mucosal activity patterns and their composite representation in a mammalian species using voltage-sensitive dyes. J. Neurosci., 16, 345-353.
    • (1996) J. Neurosci. , vol.16 , pp. 345-353
    • Kent, P.F.1    Mozell, M.M.2    Murphy, S.J.3    Hornung, D.E.4
  • 8
    • 0029394982 scopus 로고
    • Numerical simulation of airflow in the human nasal cavity
    • Keyhani, K., Scherer, P.W. and Mozell, M.M. (1995) Numerical simulation of airflow in the human nasal cavity. J. Biomech. Eng., 117, 429-441.
    • (1995) J. Biomech. Eng. , vol.117 , pp. 429-441
    • Keyhani, K.1    Scherer, P.W.2    Mozell, M.M.3
  • 9
    • 0031558018 scopus 로고    scopus 로고
    • A numerical model of nasal odorant transport for the analysis of human olfaction
    • Keyhani, K., Scherer, P.W. and Mozell, M.M. (1997) A numerical model of nasal odorant transport for the analysis of human olfaction. J. Theor. Biol., 186, 279-301.
    • (1997) J. Theor. Biol. , vol.186 , pp. 279-301
    • Keyhani, K.1    Scherer, P.W.2    Mozell, M.M.3
  • 11
    • 0027313660 scopus 로고
    • Application of computational fluid dynamics to regional dosimetry of inhaled chemicals in the upper respiratory tract of the rat
    • Kimbell, J.S., Gross, E.A., Joyner, D.R., Godo, M.N. and Morgan, K.T. (1993) Application of computational fluid dynamics to regional dosimetry of inhaled chemicals in the upper respiratory tract of the rat Toxicol. Appl. Pharmacol., 121, 253-263.
    • (1993) Toxicol. Appl. Pharmacol. , vol.121 , pp. 253-263
    • Kimbell, J.S.1    Gross, E.A.2    Joyner, D.R.3    Godo, M.N.4    Morgan, K.T.5
  • 12
    • 16644388808 scopus 로고    scopus 로고
    • Experimental and numerical determination of odorant solubility in nasal and olfactory mucosa
    • Kurtz, D.B., Zhao, K., Hornung, D.E. and Scherer, P.W. (2004) Experimental and numerical determination of odorant solubility in nasal and olfactory mucosa. Chem. Senses, 29, 763-773.
    • (2004) Chem. Senses , vol.29 , pp. 763-773
    • Kurtz, D.B.1    Zhao, K.2    Hornung, D.E.3    Scherer, P.W.4
  • 15
    • 0025986891 scopus 로고
    • Studies of inspiratory airflow patterns in the nasal passages of the F344 rat and rhesus monkey using nasal molds: Relevance to formaldehyde toxicity
    • Morgan, K.T., Kimbell, J.S., Monticello, T.M., Patra, A.L. and Fleishman, A. (1991) Studies of inspiratory airflow patterns in the nasal passages of the F344 rat and rhesus monkey using nasal molds: relevance to formaldehyde toxicity. Toxicol. Appl. Pharmacol., 110, 223-240.
    • (1991) Toxicol. Appl. Pharmacol. , vol.110 , pp. 223-240
    • Morgan, K.T.1    Kimbell, J.S.2    Monticello, T.M.3    Patra, A.L.4    Fleishman, A.5
  • 16
    • 0017184744 scopus 로고
    • Spatial patterning of response to odors in the peripheral olfactory system
    • Moulton, D.G. (1976) Spatial patterning of response to odors in the peripheral olfactory system. Physiol. Rev., 56, 578-593.
    • (1976) Physiol. Rev. , vol.56 , pp. 578-593
    • Moulton, D.G.1
  • 17
    • 0013944568 scopus 로고
    • The spatiotemporal analysis of odorants at the level of the olfactory receptor sheet
    • Mozell, M.M. (1966) The spatiotemporal analysis of odorants at the level of the olfactory receptor sheet. J. Gen. Physiol., 50, 25-41.
    • (1966) J. Gen. Physiol. , vol.50 , pp. 25-41
    • Mozell, M.M.1
  • 18
    • 0014815255 scopus 로고
    • Evidence for a chromatographic model of olfaction
    • Mozell, M.M. (1970) Evidence for a chromatographic model of olfaction. J. Gen. Physiol., 56, 46-63.
    • (1970) J. Gen. Physiol. , vol.56 , pp. 46-63
    • Mozell, M.M.1
  • 19
    • 0015868076 scopus 로고
    • Chromatographic separation of odorants by the nose: Retention times measured across in vivo olfactory mucosa
    • Mozell, M.M. and Jagodowicz, M. (1973) Chromatographic separation of odorants by the nose: Retention times measured across in vivo olfactory mucosa. Science, 181, 1247-1249.
    • (1973) Science , vol.181 , pp. 1247-1249
    • Mozell, M.M.1    Jagodowicz, M.2
  • 20
    • 0000187310 scopus 로고
    • Air currents in the upper respiratory tract and their clinical importance
    • Proetz, A.W. (1951) Air currents in the upper respiratory tract and their clinical importance. Ann. Otol. Rhinol. Laryngol., 60, 439-467.
    • (1951) Ann. Otol. Rhinol. Laryngol. , vol.60 , pp. 439-467
    • Proetz, A.W.1
  • 21
    • 0033953536 scopus 로고    scopus 로고
    • Sniffing longer rather than stronger to maintain olfactory detection threshold
    • Sobel, N., Khan, R.M., Hartley, C.A., Sullivan, E.V. and Gabrieli, J.D. (2000) Sniffing longer rather than stronger to maintain olfactory detection threshold. Chem. Senses, 25, 1-8.
    • (2000) Chem. Senses , vol.25 , pp. 1-8
    • Sobel, N.1    Khan, R.M.2    Hartley, C.A.3    Sullivan, E.V.4    Gabrieli, J.D.5
  • 22
    • 0028308889 scopus 로고
    • Olfactory neurones expressing distinct odorant receptor subtypes are spatially segregated in the nasal neuroepithelium
    • Strotmann, J., Wanner, I., Helfrich, T., Beck, A., Meinken, C., Kubick, S. and Breer, H. (1994) Olfactory neurones expressing distinct odorant receptor subtypes are spatially segregated in the nasal neuroepithelium. Cell Tissue Res., 276, 429-438.
    • (1994) Cell Tissue Res. , vol.276 , pp. 429-438
    • Strotmann, J.1    Wanner, I.2    Helfrich, T.3    Beck, A.4    Meinken, C.5    Kubick, S.6    Breer, H.7
  • 23
    • 0031889332 scopus 로고    scopus 로고
    • Computational fluid dynamics simulations of inspiratory airflow in the human nose and nasopharynx
    • Subramaniam, R.P., Richardson, R.B., Morgan, K.T. and Kimbell, J.S. (1999) Computational fluid dynamics simulations of inspiratory airflow in the human nose and nasopharynx. Inhal. Toxicol., 10, 91-120.
    • (1999) Inhal. Toxicol. , vol.10 , pp. 91-120
    • Subramaniam, R.P.1    Richardson, R.B.2    Morgan, K.T.3    Kimbell, J.S.4
  • 24
    • 0001210270 scopus 로고
    • Access of air to the respiratory tract
    • Brain, J.D., Proctor, D.F. and Reid, L.M. (eds), Marcel Dekker Inc., New York
    • Swift, D.L. and Proctor, D.F. (1977) Access of air to the respiratory tract. In Brain, J.D., Proctor, D.F. and Reid, L.M. (eds), Respiratory Defense Mechanism. Marcel Dekker Inc., New York, pp. 63-91.
    • (1977) Respiratory Defense Mechanism , pp. 63-91
    • Swift, D.L.1    Proctor, D.F.2
  • 25
    • 32544460176 scopus 로고    scopus 로고
    • Numerical Modeling of Odorant Uptake in the Rat and Bullfrog Nasal Cavities (PhD Dissertation)
    • University of Pennsylvania, Philadelphia, PA
    • Yang, C.C. (1999) Numerical Modeling of Odorant Uptake in the Rat and Bullfrog Nasal Cavities (PhD Dissertation). University of Pennsylvania, Philadelphia, PA.
    • (1999)
    • Yang, C.C.1
  • 26
    • 0023582951 scopus 로고
    • A quantitative analysis of sniffing strategies in rats performing odor detection tasks
    • Youngentob, S.L., Mozell, M.M., Sheehe, P.R. and Hornung, D.E. (1987) A quantitative analysis of sniffing strategies in rats performing odor detection tasks. Physiol. Behav., 41, 59-69.
    • (1987) Physiol. Behav. , vol.41 , pp. 59-69
    • Youngentob, S.L.1    Mozell, M.M.2    Sheehe, P.R.3    Hornung, D.E.4
  • 27
    • 32544435706 scopus 로고    scopus 로고
    • Numerical modeling of nasal obstruction and endoscopic surgical intervention: Outcome to airflow and olfaction
    • in press
    • Zhao, K., Pribitkin, E.A., Cowart, B.J., Rosen, D., Scherer, P.W. and Dalton, P. (2006) Numerical modeling of nasal obstruction and endoscopic surgical intervention: Outcome to airflow and olfaction. Am. J. Rhinol., in press.
    • (2006) Am. J. Rhinol.
    • Zhao, K.1    Pribitkin, E.A.2    Cowart, B.J.3    Rosen, D.4    Scherer, P.W.5    Dalton, P.6
  • 28
    • 10644250420 scopus 로고    scopus 로고
    • Effect of anatomy on human nasal air flow and odorant transport patterns: Implications for olfaction
    • Zhao, K., Scherer, P.W., Hajiloo, S.A. and Dalton, P. (2004) Effect of anatomy on human nasal air flow and odorant transport patterns. implications for olfaction. Chem. Senses, 29, 365-379.
    • (2004) Chem. Senses , vol.29 , pp. 365-379
    • Zhao, K.1    Scherer, P.W.2    Hajiloo, S.A.3    Dalton, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.