The flavonoid quercetin induces hypoxia-inducible factor-1α (HIF-1α) and inhibits cell proliferation by depleting intracellular iron

Free Radical Research

Volumn 41, Issue 3, 2007, Pages 342-356

  Triantafyllou, Anastasia ^a   Liakos, Panagiotis ^a   Tsakalof, Andreas ^a   Chachami, Georgia ^a   Paraskeva, Efrosyni ^a   Molyvdas, Pashalis Adam ^a   Georgatsou, Elena ^a   Simos, George ^a   Bonanou, Sophia ^a  

^a UNIVERSITY OF THESSALY   (Greece)

Author keywords

Ascorbate; Ferric citrate; HIF 1 ; Hypoxia inducible factor 1; Iron; Quercetin

Indexed keywords

ASCORBIC ACID; CALCEIN; FERRIC CITRATE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IRON; IRON CHELATE; QUERCETIN;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; BREATHING MUSCLE; CELL CYCLE ARREST; CELL PROLIFERATION; CHELATION; CONTROLLED STUDY; DNA SYNTHESIS INHIBITION; GROWTH INHIBITION; HELA CELL; HUMAN; HUMAN CELL; IRON DEPLETION; NONHUMAN; PROTEIN EXPRESSION; RABBIT; SMOOTH MUSCLE FIBER;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANTIOXIDANTS; CELL PROLIFERATION; CHELATING AGENTS; FERRIC COMPOUNDS; FLAVONOIDS; FLUORESCEINS; GENE EXPRESSION; HELA CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IRON; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; QUERCETIN; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 33947113793     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.1080/10715760601055324     Document Type: Article

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