Beneficial effects of statins on the microcirculation during sepsis: The role of nitric oxide

British Journal of Anaesthesia

Volumn 98, Issue 2, 2007, Pages 163-175

  McGown, C C ^a   Brookes, Z L S ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Complications, sepsis; Inhibitors, reductase, hydroxymethylglutaryl CoA; Microcirculation; Nitric oxide; Nitric oxide synthetase

Indexed keywords

3 HYDROXY 3 METHYLGLUTARYL COENZYME A; ATORVASTATIN; CELL ADHESION MOLECULE; CERIVASTATIN; CHOLESTEROL; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FLUINDOSTATIN; GAMMA INTERFERON; GERANYLGERANYL PYROPHOSPHATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPID; MEVALONIC ACID; MEVINOLIN; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PRAVASTATIN; PROTEIN KINASE B; ROSUVASTATIN; SIMVASTATIN; STAT1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTERY TONE; ATHEROSCLEROSIS; BLOOD PRESSURE; BLOOD VESSEL TONE; CELL INTERACTION; CEREBROVASCULAR DISEASE; CONCENTRATION (PARAMETERS); CORONARY ARTERY DISEASE; DOWN REGULATION; DRUG EFFICACY; DRUG MECHANISM; DYSLIPIDEMIA; ENDOTHELIUM CELL; ENZYME ACTIVITY; GAP JUNCTION; HUMAN; HYPERCHOLESTEROLEMIA; INHIBITION KINETICS; LABORATORY TEST; LEUKOCYTE ADHERENCE; LEUKOCYTE MIGRATION; LIPID SOLUBILITY; LIPOPHILICITY; MICROCIRCULATION; NONHUMAN; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN EXPRESSION; PROTEIN PROCESSING; REVIEW; SEPSIS; SURVIVAL RATE; TIGHT JUNCTION; TREATMENT OUTCOME; VASCULAR ENDOTHELIUM; ANIMAL; CELL ADHESION; DRUG EFFECT; LEUKOCYTE; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; CELL ADHESION; ENDOTHELIUM, VASCULAR; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LEUKOCYTES; MICROCIRCULATION; NITRIC OXIDE; SEPSIS;

EID: 33847729386     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/ael358     Document Type: Review

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