Cardiovascular alterations in septic shock

Journal of Antimicrobial Chemotherapy

Volumn 41, Issue SUPPL. A, 1998, Pages 9-15

  Vincent, Jean Louis ^a  

^a ERASME HOSPITAL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; HISTAMINE; IMMUNOMODULATING AGENT; INTERLEUKIN 1; KININ; NITRIC OXIDE; OXYGEN RADICAL; PROSTAGLANDIN; TUMOR NECROSIS FACTOR;

BLOOD VESSEL TONE; CONFERENCE PAPER; HEART MUSCLE CONTRACTILITY; HUMAN; IMMUNOTHERAPY; SEPSIS;

BLOOD PRESSURE; CARDIAC OUTPUT; HEART; HUMANS; MYOCARDIAL CONTRACTION; MYOCARDIUM; NITRIC OXIDE; OXYGEN; SHOCK, SEPTIC;

EID: 0031965301     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/41.suppl_1.9     Document Type: Conference Paper

References (70)

1. Bakker, J., Gris, P., Coffernils, M., Kahn, R. J. & Vincent, J. L. (1996). Serial blood lactate levels can predict the development of multiple organ failure following septic shock. American Journal of Surgery 171, 221-6.
2. Friedman, G., Berlot, G., Kahn, R. J. & Vincent, J. L. (1995). Combined measurements of blood lactate concentrations and gastric intramucosal pH in patients with severe sepsis. Critical Care Medicine 23, 1184-93.
3. 2 uptake during endotoxemia. Journal of Applied Physiology 64, 2410-9.
4. Zhang, H. & Vincent, J. L. (1993). Oxygen extraction is altered by endotoxin during tamponade-induced stagnant hypoxia in the dog. Circulatory Shock 40, 168-76.
5. Vicaut, E., Hou, X., Paygen, D., Bousseau, A. & Tedgui, A. (1991). Acute effects of tumour necrosis factor on the micro circulation in rat cremaster muscle. Journal of Clinical Investigation 87, 1537-40.
6. Hollenberg, S. M., Cunnion, R. E. & Parrillo, J. E. (1991). The effect of tumor necrosis factor on vascular smooth muscle. Chest 100, 1133-7.
7. Schirmer, J. W., Schirmer, J. M. & Fry, D. E. (1989). Recombinant human tumor necrosis factor produces hemodynamic changes characteristic of sepsis and endotoxemia. Archives of Surgery 124, 445-8.
8. McKenna, T. M. (1990). Prolonged exposure of rat aorta to low levels of endotoxin in vitro results in impaired contractility. Journal of Clinical Investigation 86, 160-8.
9. Gray, G. A., Furman, B. L. & Parratt, J. R. (1990). Endotoxininduced impairment of vascular reactivity in the pithed rat: role of arachidonic acid metabolites. Circulatory Shock 31, 395-406.
10. Silverman, H. J., Penaranda, R., Orens, J. B. & Lee, N. H. (1993). Impaired beta-adrenergic receptor stimulation of cyclic adenosine monophosphate in human septic shock: association with myocardial hyporesponsiveness to catecholamines. Critical Care Medicine 21, 31-9.
11. Julou-Schaeffer, G., Gray, G. A., Fleming, I, Schott, C., Parratt, J. R. & Stoclet, J. C. (1990). Loss of vascular responsiveness induced by endotoxin involves L-arginine pathway. American Journal of Physiology 259, H1038-43.
12. Parker, M. M., Suffredini, A. F., Natanson, C., Ognibene, F. P., Shelhamer, J. H. & Parrillo, J. E. (1989). Responses of left ventricular function in survivors and nonsurvivors of septic shock. Journal of Critical Care 4, 19-25.
13. Groeneveld, A. B., Nauta, J. J. & Thijs, L. G. (1988). Peripheral vascular resistance in septic shock: its relation to outcome. Intensive Care Medicine 14, 141-7.
14. Vincent, J. L., Gris, P., Coffernils, M., Leon, M., Pinsky, M., Reuse, C. et al. (1992). Myocardial depression characterizes the fatal course of septic shock. Surgery 111, 660-7.
15. Pinsky, M. R., Vincent, J. L., Deviere, J., Alegre, M., Kahn, R. J. & Dupont, E. (1993). Serum cytokine levels in human septic shock. Relation to multiple-system organ failure and mortality. Chest 103, 565-75.
16. Abel, F. L. (1989). Myocardial function in sepsis and endotoxin shock. American Journal of Physiology 257, R1265-81.
17. D'Orio, V., Mendes, P., Saad, G. & Marcelle, R. (1990). Accuracy in early prediction of prognosis of patients with septic shock by analysis of simple indices: prospective study. Critical Care Medicine 18,1339-45.
18. Parker, M. M., Shelhamer, J. H., Bacharach, S. L., Green, M. V., Natanson, C., Frederick T. M. et al. (1984). Profound but reversible myocardial depression in patients with septic shock. Annals of Internal Medicine 100, 483-90.
19. Vincent, J. L, Reuse, C., Frank, N., Contempre, B. & Kahn, R. J. (1989). Right ventricular dysfunction in septic shock: assessment by measurements of right ventricular ejection fraction using the thermodilution technique. Acta Anaesthesiologica Scandinavica 33, 34-8.
20. Vincent, J. L, Weil, M. H., Puri, V. & Carlson, R. W. (1981). Circulatory shock associated with purulent peritonitis. American Journal of Surgery 142, 262-70.
21. Goldfarb, R. D., Nightingale, L. M., Kish, P., Weber, P. B. & Loegering, D. J. (1986). Left ventricular function during lethal and sublethal endotoxemia in swine. American Journal of Physiology 251, H364-73.
22. Lang, C. H., Bagby, G. J., Ferguson, J. L. & Spitzer, J. J. (1984). Cardiac output and redistribution of organ blood flow in hypermetabolic sepsis. American Journal of Physiology 246, R331-7.
23. Cunnion, R. E., Schaer, G. L., Parker, M. M., Natanson, C. & Parrillo, J. E. (1986). The coronary circulation in human septic shock. Circulation 73, 637-44.
24. Dhainaut, J. F., Huyghebaert, M. F., Monsallier, J. F., Lefevre, G., Dall'Ava-Santucci, J., Brunei, F. et al. (1987). Coronary hemodynamics and myocardial metabolism of lactate, free fatty acids, glucose, and ketones in patients with septic shock. Circulation 75, 533-41.
25. Hotchkiss, R. S. & Karl, I. E. (1992). Revaluation of the role of cellular hypoxia and bioenergetic failure in sepsis. Journal of the American Medical Association 267, 1503-10.
26. Solomon, M. A., Correa, R., Alexander, H. R., Koev, L. A., Cobb, J. P., Kim, D. K. et al. (1994). Myocardial energy metabolism and morphology in a canine model of sepsis. American Journal of Physiology 266, H757-68.
27. Lefer, A. M. (1970). Role of a myocardial depressant factor in the pathogenesis of circulatory shock. Federation Proceedings 29, 1836-47.
28. Reilly, J. M., Cunnion, R. E., Burch-Whitman, C., Parker, M. M., Shelhamer, J. H. & Parrillo, J. E. (1989). A circulating myocardial depressant substance is associated with cardiac dysfunction and peripheral hypoperfusion (lactic acidemia) in patients with septic shock. Chest 95, 1072-80.
29. Parrillo, J. E., Burch, C., Shelhamer, J. H., Parker, M. M., Natanson, C. & Schuette, W. (1985). A circulating myocardial depressant substance in humans with septic shock. Journal of Clinical Investigation 76, 1539-53.
30. Kumar, A., Thota, V., Dee, L., Olson, J., Uretz, E. & Parrillo, J. E. (1996). Tumor necrosis factor a and interleukin 1B are responsible for in vitro myocardial cell depression induced by human septic shock serum. Journal of Experimental Medicine 183, 949-58.
31. Gulick, T., Chung, M. K., Pieper, S. J., Lange, L. G. & Schreiner, G. F. (1989). Interleukin 1 and tumor necrosis factor inhibit cardiac myocyte beta-adrenergic responsiveness. Proceedings of the National Academy of Sciences of the USA 86, 6753.
32. Heard, S. O., Perkins, M. W. & Fink, M. P. (1992). Tumor necrosis factor-alpha causes myocardial depression in guinea pigs. Critical Care Medicine 20, 523-7.
33. Natanson, C., Eichenholz, P. W., Danner, R. L., Eichacker, P. Q., Hoffman, W. D., Kuo, G. C. et al. (1989). Endotoxin and tumor necrosis factor challenges in dogs simulate the cardiovascular profile of human septic shock. Journal of Experimental Medicine 169, 823-32.
34. Pagani, F. D., Baker, L S., Hsi, C., Knox, M., Fink, M. P. & Visner, M. S. (1992). Left ventricular systolic and diastolic dysfunction after infusion of tumor necrosis factor-a in conscious dogs. Journal of Clinical Investigation 90, 389-98.
35. Eichenholz, P. W., Eichacker, P. Q., Hoffman, W. D., Banks, S. M., Parrillo, J. E., Danner, R. L. et al. (1992). Tumor necrosis factor challenges in canines: patterns of cardiovascular dysfunction. American Journal of Physiology 263, H668-75.
36. Walley, K. R., Hebert, P. C., Wakai, Y., Wilcox, P. G., Road, J. D. & Cooper, D. J. (1994). Decrease in left ventricular contractility after tumor necrosis factor-α infusion in dogs. Journal of Applied Physiology 76, 1060-7.
37. Herbertson, M. J., Werner, H. A., Goddard, C. M., Russell, J. A., Wheeler, A., Coxon, R. et al. (1995). Anti-tumor necrosis factor-α prevents decreased ventricular contractility in endotoxemic pigs. American Journal of Respiratory and Critical Care Medicine 152, 480-8.
38. Kapadia, S., Lee, J., Torre-Amione, G., Birdsall, H. H., Ma, T. S. & Mann, D. L. (1995). Tumor necrosis factor-α gene and protein expression in adult feline myocardium after endotoxin administration. Journal of Clinical Investigation 96, 1042-52.
39. Hosenpud, J. D. (1993). The effects of interleukin 1 on myocardial function and metabolism. Clinical Immunology and Immunopathoiogy 68, 175-80.
40. Okusawa, S., Gelfand, J. A., Ikejima, T., Connolly, R. J. & Dinarello, C. A. (1988). Interleukin 1 induces a shock-like state in rabbits. Synergism with tumor necrosis factor and the effect of cyclooxygenase inhibition. Journal of Clinical Investigation 81, 1162-72.
41. Waage, A. & Espevik, T. (1988). lnterleukin-1 potentiates the lethal effect of tumor necrosis factor alpha/cachectin in mice. Journal of Experimental Medicine 167, 1987-92.
42. Vincent, J. L., Bakker, J., Marécaux, G., Schandene, L., Kahn, R. J. & Dupont, E. (1992). Administration of anti-TNF antibody improves left ventricular function in septic shock patients. Chest 101, 810-5.
43. Vincent, J. L., Slotman, G., van Leeuwen, P. A. M. et al. (1995). IL-1ra administration does not improve cardiac function in patients with severe sepsis. Intensive Care Medicine 21, S11 (Abstract).
44. Camussi, G., Alloatti, G., Montrucchio, G., Meda, M. & Emanuelli, G. (1984). Effect of platelet activating factor on guineapig papillary muscle. Experientia 40, 697-9.
45. Chang, S. W., Feddersen, C. O., Henson, P. M. & Voelkel, N. F. (1987). Platelet-activating factor mediates hemodynamic changes and lung injury in endotoxin-treated rats. Journal of Clinical Investigation 79, 1498-509.
46. Zhang, H., Spapen, H., Nguyen, D. N., Benlabed, M., Buurman, W. A. & Vincent, J. L. (1994). Protective effects of N-acetyl-L-cysteine in endotoxemia. American Journal of Physiology 266, H1746-54.
47. Silva, A. T. & Cohen, J. (1992). Role of interferon-gamma in experimental Gram-negative sepsis. Journal of Infectious Diseases 166, 331-5.
48. Fujioka, K., Isago, T., Flynn, J. T., Traber, L. T. & Herndon, D. N. (1991). Thromboxane synthase inhibition and cardiopulmonary function during endotoxemia in sheep. Journal of Applied Physiology 71, 1376-81.
49. Grocott-Mason, R., Fort, S., Lewis, M. J. & Shah, A. M. (1994). Myocardial relaxant effect of exogenous nitric oxide in isolated ejecting hearts. American Journal of Physiology 266, H1699-705.
50. Kumar, A., Kosuri, R., Thota, V., Stolz, V., Dee, L., Olson, J. et al. (1993). Effect of nitric oxide synthetase inhibition of human septic serum-induced myocardial cell depression In vitro. Circulatory Shock 39, 22 (Abstract).
51. Finkel, M. S., Oddis, C. V., Jacob, T. D., Watkins, S. C., Hattler, B. G. & Simmons, R. L. (1992). Negative inotropic effects of cytokines on the heart mediated by nitric oxide. Science 257, 378-9.
52. 2+i and cell contraction in cultured chick ventricular myocytes. Circulatory Research 75, 285-95.
53. Calandra, T., Baumgartner, J. D., Grau, G. E., Wu, M. M., Lambert, P. H., Schellekens, J. et al. (1990). Prosgnostic values of tumor necrosis factor/cachectin, interleukin-1, interferon-alpha, and interferon-gamma in the serum of patients with septic shock. Journal of Infectious Diseases 161, 982-7.
54. Bakker, J., Coffernils, M., Leon, M., Gris, P. & Vincent, J. L (1991). Blood lactate levels are superior to oxygen-derived variables in predicting outcome in human septic shock. Chest 99, 956-62.
55. McDonough, K. H., Brumfield, B. A. & Lang, C. H. (1986). In vitro myocardial performance after lethal and nonlethal doses of endotoxin. American Journal of Physiology 250, H240-6.
56. Weisel, R. D., Vito, L., Dennis, R. C., Valeri, C. R. & Hechtman, H. B. (1977). Myocardial depression during sepsis. American Journal of Surgery 133, 510-21.
57. Parker, M. M., McCarthy, K. E., Ognibene, F. P. & Parrillo, J. E. (1990). Right ventricular dysfunction and dilatation, similar to left ventricular changes, characterize the cardiac depression of septic shock in humans. Chest 97, 126-31.
58. Hoffman, M. J., Greenfield, L. J., Sugerman, J. H. & Tatum, J. L. (1983). Unsuspected right ventricular dysfunction in shock and sepsis. Annals of Surgery 198, 307-19.
59. Horvath, C. J., Kaplan, J. E. & Malik, A. B. (1991). Role of platelet-activating factor in mediating tumor necrosis factor alphainduced pulmonary vasoconstriction and plasma-lymph protein transport. American Review of Respiratory Disease 144, 1337-41.
60. Kubo, K. & Kobayashi, T. (1985). Effects of OKY-046, a selective thromboxane synthetase inhibitor, on endotoxin-induced lung injury in unanesthetized sheep. American Review of Respiratory Disease 132, 494-9.
61. Weitzberg, E., Lundberg, J. M. & Rudehill, A. (1995). Inhibitory effects of diclofenac on the endotoxin shock response in relation to endothelin turnover in the pig. Acta Anaesthesiologica Scandinavica 39, 50-9.
62. Metrangolo, L., Fiorillo, M., Friedman, G., Silance, P. G., Kahn, R. J., Novelli, G. P. et al. (1995). The early hemodynamic course of septic shock. Critical Care Medicine 23, 1971-5.
63. Vincent, J. L., Roman, A. & Kahn, R. J. (1990). Dobutamine administration in septic shock: addition to a standard protocol. Critical Care Medicine 18, 689-93.
64. Petros, A., Lamb, G., Leone, A., Moncada, S., Bennett, D. & Vallance, P. (1994). Effects of a nitric oxide synthase inhibitor in humans with septic shock. Cardiovascular Research 28, 34-9.
65. Preiser, J. C., Lejeune, P., Roman, A., Carlier, E., De Backer, D., Leeman, M. et al. (1995). Methylene blue administration in septic shock: a clinical trial. Critical Care Medicine 23, 259-64.
66. Schneider, F., Lutun, P., Hasselmann, M., Stoclet, J. C. & Tempe, J. D. (1992). Methylene blue increases systemic vascular resistance in human septic shock. Preliminary observations. Intensive Care Medicine 18, 309-11.
67. Zhang, H., Rogiers, P., Friedman, G., Preiser, J. C., Spapen, H., Buurman, W. A. et al. (1996). Effects of nitric oxide donor SIN-1 on oxygen availability and regional blood flow during endotoxic shock. Archives of Surgery 131, 767-74.
68. 2 fragment of an anti-tumor necrosis factor-α monoclonal antibody in patients with severe sepsis. In Sepsis: Current Perspectives in Pathophysiology and Therapy (Reinhart, K., Eyrich, K. & Sprung, C., Eds), pp. 357-70. SpringerVerlag, Berlin.
69. Zhang, H., Spapen, H., Nguyen, D. N., Benlabed, M., Buurman, W. A. & Vincent, J. L. (1994). Protective effects of N-acetyl-L-cysteine in endotoxemia. American Journal of Physiology 266, H1746-54.
70. Zhang, H., Spapen, H., Manikis, P., Rogiers, P., Metz, G., Buurman, W. A. et al. (1995). Tirilazad mesylate (U74006F) inhibits effects of endotoxin in dogs. American Journal of Physiology 268, H1847-55.