Acute activation and phosphorylation of endothelial nitric oxide synthase by HMG-CoA reductase inhibitors

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 287, Issue 2 56-2, 2004, Pages

  Harris, M Brennan ^a,c   Blackstone, Michele A ^a   Sood, Sarika G ^a   Li, Chunying ^a   Goolsby, Jonathan M ^a   Venema, Virginia J ^a   Kemp, Bruce E ^b   Venema, Richard C ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c The College of William and Mary   (United States)

Author keywords

Endothelium; Statins; Vascular

Indexed keywords

ANTIBODY; ANTILIPEMIC AGENT; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC GMP; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; KT 5720; MEVALONIC ACID; MEVINOLIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PRAVASTATIN; PROTEIN KINASE B; PROTEIN KINASE INHIBITOR; SERINE; STATINE; THREONINE; WORTMANNIN;

ANIMAL CELL; ARTICLE; CATTLE; CELL SECRETION; CELL STIMULATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM; WESTERN BLOTTING;

ANIMALS; AORTA; CATTLE; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III;

EID: 3242733932     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00214.2004     Document Type: Article

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