Mimicry peptides of human PDC-E2 163-176 peptide, the immunodominant T- cell epitope of primary biliary cirrhosis

Hepatology

Volumn 31, Issue 6, 2000, Pages 1212-1216

  Shimoda, Shinji ^a   Nakamura, Minoru ^a   Shigematsu, Hirohisa ^a   Tanimoto, Hironori ^a   Gushima, Toshihumi ^a   Gershwin, M Eric ^b   Ishibashi, Hiromi ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; EPITOPE; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; SYNTHETIC PEPTIDE;

ARTICLE; BILIARY CIRRHOSIS; CASE REPORT; ESCHERICHIA COLI; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LYMPHOCYTE CLONE; PEPTIDE ANALYSIS; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0034076796     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2000.8090     Document Type: Article

References (6)

1. Fujinami RS, Oldstone MBA. Amino acid homology between the encephalitogenic site of myelin basic protein and virus: mechanism for autoimmunity. Science 1985;230:1043-1045.
2. Oldstone MBA. Molecular mimicry and autoimmune disease. Cell 1987;50:819-820.
3. Wucherpfennig KW, Strominger Jl. Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein. Cell 1995;80:695-705.
4. Gautam AM, Pearson CI, Smilek DE, Steinman L, McDevitt HO. A polyalanine peptide with only five native myelin basic protein residues induces autoimmune encephalomyelitis. J Exp Med 1992;176:605-609.
5. Barnaba V, Sinigaglia F. Molecular mimicry and T cell-mediated autoimmune disease. J Exp Med 1997;185:1529-1531.
6. Zhao ZS, Granucci F, Yeh L, Schaffer PA, Cantor H. Molecular mimicry by herpes simplex virus-type 1: autoimmune disease after viral infection. Science 1998;279:1344-1347.