A network of conserved interactions regulates the allosteric signal in a glutamine amidotransferase

Biochemistry

Volumn 46, Issue 8, 2007, Pages 2156-2173

  Amaro, Rommie E ^a,c   Sethi, Anurag ^a   Myers, Rebecca S ^b,d   Davisson, V Jo ^b   Luthey Schulten, Zaida A ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b PURDUE UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Robert C Byrd Center for Pharmacy Education   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC TRANSITION; HINGE-OPENING MOTION; SUBSTRATE-BINDING SITE; UNDOCKING;

CORRELATION METHODS; GLYCEROL; MOLECULAR DYNAMICS; PRINCIPAL COMPONENT ANALYSIS;

ENZYMES;

AMIDE; GLUTAMINE; GLUTAMINE AMIDOTRANSFERASE; GLYCEROPHOSPHATE; IMIDAZOLE; RIBONUCLEOTIDE; SYNTHETASE; TRANSFERASE; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; ENZYME ANALYSIS; ENZYME SUBSTRATE; MOLECULAR DYNAMICS; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

ALLOSTERIC REGULATION; AMINOHYDROLASES; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; IMIDAZOLES; KINETICS; MODELS, MOLECULAR; PRINCIPAL COMPONENT ANALYSIS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RIBONUCLEOTIDES; SACCHAROMYCES CEREVISIAE;

EID: 33847609615     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi061708e     Document Type: Article

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