메뉴 건너뛰기




Volumn 178, Issue 5, 2007, Pages 2916-2922

Increased positive selection of B1 cells and reduced B cell tolerance to intracellular antigens in c1q-deficient mice

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; COMPLEMENT COMPONENT C1Q; IMMUNOGLOBULIN M; IMMUNOGLOBULIN M ANTIBODY;

EID: 33847389238     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.178.5.2916     Document Type: Article
Times cited : (31)

References (45)
  • 2
    • 2542505506 scopus 로고    scopus 로고
    • The role of complement in the development of systemic lupus erythematosus
    • Manderson, A. P., M. Botto, and M. J. Walport. 2004. The role of complement in the development of systemic lupus erythematosus. Annu. Rev. Immunol. 22: 431-456.
    • (2004) Annu. Rev. Immunol , vol.22 , pp. 431-456
    • Manderson, A.P.1    Botto, M.2    Walport, M.J.3
  • 4
    • 5044225201 scopus 로고    scopus 로고
    • A protective role for innate immunity in systemic lupus erythematosus
    • Carroll, M. C. 2004. A protective role for innate immunity in systemic lupus erythematosus. Nat. Rev. Immunol. 4: 825-831.
    • (2004) Nat. Rev. Immunol , vol.4 , pp. 825-831
    • Carroll, M.C.1
  • 5
    • 0028288510 scopus 로고
    • Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes
    • Casciola-Rosen, L. A., G. Anhalt, and A. Rosen. 1994. Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes. J. Exp. Med. 179: 1317-1330.
    • (1994) J. Exp. Med , vol.179 , pp. 1317-1330
    • Casciola-Rosen, L.A.1    Anhalt, G.2    Rosen, A.3
  • 6
    • 0036644073 scopus 로고    scopus 로고
    • Blebs and apoptotic bodies are B cell autoantigens
    • Cocca, B. A., A. M. Cline, and M. Z. Radic. 2002. Blebs and apoptotic bodies are B cell autoantigens. J. Immunol. 169: 159-166.
    • (2002) J. Immunol , vol.169 , pp. 159-166
    • Cocca, B.A.1    Cline, A.M.2    Radic, M.Z.3
  • 7
    • 0031825552 scopus 로고    scopus 로고
    • Systemic exposure to irradiated apoptotic cells induces autoantibody production
    • Mevorach, D., J. L. Zhou, X. Song, and K. B. Elkon. 1998. Systemic exposure to irradiated apoptotic cells induces autoantibody production. J. Exp. Med. 188: 387-392.
    • (1998) J. Exp. Med , vol.188 , pp. 387-392
    • Mevorach, D.1    Zhou, J.L.2    Song, X.3    Elkon, K.B.4
  • 9
    • 0035284867 scopus 로고    scopus 로고
    • The globular heads of C1q specifically recognize surface blebs of apoptotic vascular endothelial cells
    • Navratil, J. S., S. C. Watkins, J. J. Wisnieski, and J. M. Ahearn. 2001. The globular heads of C1q specifically recognize surface blebs of apoptotic vascular endothelial cells. J. Immunol. 166: 3231-3239.
    • (2001) J. Immunol , vol.166 , pp. 3231-3239
    • Navratil, J.S.1    Watkins, S.C.2    Wisnieski, J.J.3    Ahearn, J.M.4
  • 10
    • 0031569975 scopus 로고    scopus 로고
    • C1q binds directly and specifically to surface blebs of apoptotic human keratinocytes: Complement deficiency and systemic lupus erythematosus revisited
    • Korb, L. C., and J. M. Ahearn. 1997. C1q binds directly and specifically to surface blebs of apoptotic human keratinocytes: complement deficiency and systemic lupus erythematosus revisited. J. Immunol. 158: 4525-4528.
    • (1997) J. Immunol , vol.158 , pp. 4525-4528
    • Korb, L.C.1    Ahearn, J.M.2
  • 11
    • 0035903289 scopus 로고    scopus 로고
    • C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells
    • Ogden, C. A., A. deCathelineau, P. R. Hoffmann, D. Bratton, B. Ghebrehiwet, V. A. Fadok, and P. M. Henson. 2001. C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells. J. Exp. Med. 194: 781-795.
    • (2001) J. Exp. Med , vol.194 , pp. 781-795
    • Ogden, C.A.1    deCathelineau, A.2    Hoffmann, P.R.3    Bratton, D.4    Ghebrehiwet, B.5    Fadok, V.A.6    Henson, P.M.7
  • 13
    • 0032416392 scopus 로고    scopus 로고
    • Complement-dependent clearance of apoptotic cells by human macrophages
    • Mevorach, D., J. O. Mascarenhas, D. Gershov, and K. B. Elkon. 1998. Complement-dependent clearance of apoptotic cells by human macrophages. J. Exp. Med. 188: 2313-2320.
    • (1998) J. Exp. Med , vol.188 , pp. 2313-2320
    • Mevorach, D.1    Mascarenhas, J.O.2    Gershov, D.3    Elkon, K.B.4
  • 19
    • 0034939330 scopus 로고    scopus 로고
    • Intact B cell tolerance in the absence of the first component of the classical complement pathway
    • Cutler, A. J., R. J. Cornall, H. Ferry, A. P. Manderson, M. Botto, and M. J. Walport. 2001. Intact B cell tolerance in the absence of the first component of the classical complement pathway. Eur. J. Immunol. 31: 2087-2093.
    • (2001) Eur. J. Immunol , vol.31 , pp. 2087-2093
    • Cutler, A.J.1    Cornall, R.J.2    Ferry, H.3    Manderson, A.P.4    Botto, M.5    Walport, M.J.6
  • 20
    • 0242695061 scopus 로고    scopus 로고
    • The cellular location of self-antigen determines the positive and negative selection of autoreactive B cells
    • Ferry, H., M. Jones, D. J. Vaux, I. S. Roberts, and R. J. Cornall. 2003. The cellular location of self-antigen determines the positive and negative selection of autoreactive B cells. J. Exp. Med. 198: 1415-1425.
    • (2003) J. Exp. Med , vol.198 , pp. 1415-1425
    • Ferry, H.1    Jones, M.2    Vaux, D.J.3    Roberts, I.S.4    Cornall, R.J.5
  • 21
    • 33744905326 scopus 로고    scopus 로고
    • Signals from a self-antigen induce positive selection in early B cell ontogeny but are tolerogenic in adults
    • Ferry, H., T. L. Crockford, J. C. Leung, and R. J. Cornall. 2006. Signals from a self-antigen induce positive selection in early B cell ontogeny but are tolerogenic in adults. J. Immunol. 176: 7402-7411.
    • (2006) J. Immunol , vol.176 , pp. 7402-7411
    • Ferry, H.1    Crockford, T.L.2    Leung, J.C.3    Cornall, R.J.4
  • 22
    • 0034599499 scopus 로고    scopus 로고
    • Deficiency in serum immunoglobulin (Ig)M predisposes to development of IgG autoantibodies
    • Ehrenstein, M. R., H. T. Cook, and M. S. Neuberger. 2000. Deficiency in serum immunoglobulin (Ig)M predisposes to development of IgG autoantibodies. J. Exp. Med. 191: 1253-1258.
    • (2000) J. Exp. Med , vol.191 , pp. 1253-1258
    • Ehrenstein, M.R.1    Cook, H.T.2    Neuberger, M.S.3
  • 23
    • 12344327400 scopus 로고    scopus 로고
    • Predominant role of IgM-dependent activation of the classical pathway in the clearance of dying cells by murine bone marrow-derived macrophages in vitro
    • Quartier, P., P. K. Potter, M. R. Ehrenstein, M. J. Walport, and M. Botto. 2005. Predominant role of IgM-dependent activation of the classical pathway in the clearance of dying cells by murine bone marrow-derived macrophages in vitro. Eur. J. Immunol. 35: 252-260.
    • (2005) Eur. J. Immunol , vol.35 , pp. 252-260
    • Quartier, P.1    Potter, P.K.2    Ehrenstein, M.R.3    Walport, M.J.4    Botto, M.5
  • 25
    • 0035056376 scopus 로고    scopus 로고
    • B cell development pathways
    • Hardy, R. R., and K. Hayakawa. 2001. B cell development pathways. Annu. Rev. Immunol. 19: 595-621.
    • (2001) Annu. Rev. Immunol , vol.19 , pp. 595-621
    • Hardy, R.R.1    Hayakawa, K.2
  • 26
    • 0033575778 scopus 로고    scopus 로고
    • B cell antigen receptor specificity and surface density together determine B-1 versus B-2 cell development
    • Lam, K. P., and K. Rajewsky. 1999. B cell antigen receptor specificity and surface density together determine B-1 versus B-2 cell development. J. Exp. Med. 190: 471-477.
    • (1999) J. Exp. Med , vol.190 , pp. 471-477
    • Lam, K.P.1    Rajewsky, K.2
  • 28
    • 0035803468 scopus 로고    scopus 로고
    • Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen
    • Schneider, P., H. Takatsuka, A. Wilson, F. Mackay, A. Tardivel, S. Lens, T. G. Cachero, D. Finke, F. Beermann, and S. Tschopp. 2001. Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen. J. Exp. Med. 194: 1691-1697.
    • (2001) J. Exp. Med , vol.194 , pp. 1691-1697
    • Schneider, P.1    Takatsuka, H.2    Wilson, A.3    Mackay, F.4    Tardivel, A.5    Lens, S.6    Cachero, T.G.7    Finke, D.8    Beermann, F.9    Tschopp, S.10
  • 29
    • 0034601020 scopus 로고    scopus 로고
    • BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population
    • Thompson, J. S., P. Schneider, S. L. Kalled, L. Wang, E. A. Lefevre, T. G. Cachero, F. MacKay, S. A. Bixler, M. Zafari, Z. Y. Liu, et al. 2000. BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population. J. Exp. Med. 192: 129-135.
    • (2000) J. Exp. Med , vol.192 , pp. 129-135
    • Thompson, J.S.1    Schneider, P.2    Kalled, S.L.3    Wang, L.4    Lefevre, E.A.5    Cachero, T.G.6    MacKay, F.7    Bixler, S.A.8    Zafari, M.9    Liu, Z.Y.10
  • 30
    • 0036169940 scopus 로고    scopus 로고
    • CXCL13 is required for B1 cell homing, natural antibody production, and body cavity immunity
    • Ansel, K. M., R. B. Harris, and J. G. Cyster. 2002. CXCL13 is required for B1 cell homing, natural antibody production, and body cavity immunity. Immunity 16: 67-76.
    • (2002) Immunity , vol.16 , pp. 67-76
    • Ansel, K.M.1    Harris, R.B.2    Cyster, J.G.3
  • 31
    • 16344385845 scopus 로고    scopus 로고
    • Human innate B cells: A link between host defense and autoimmunity?
    • Milner, E. C., J. Anolik, A. Cappione, and I. Sanz. 2005. Human innate B cells: a link between host defense and autoimmunity? Springer Semin. Immunopathol. 26: 433-452.
    • (2005) Springer Semin. Immunopathol , vol.26 , pp. 433-452
    • Milner, E.C.1    Anolik, J.2    Cappione, A.3    Sanz, I.4
  • 32
    • 16344380083 scopus 로고    scopus 로고
    • Inherent specificities in natural antibodies: A key to immune defense against pathogen invasion
    • Baumgarth, N., J. W. Tung, and L. A. Herzenberg. 2005. Inherent specificities in natural antibodies: a key to immune defense against pathogen invasion. Springer Semin. Immunopathol. 26: 347-362.
    • (2005) Springer Semin. Immunopathol , vol.26 , pp. 347-362
    • Baumgarth, N.1    Tung, J.W.2    Herzenberg, L.A.3
  • 33
    • 33745411114 scopus 로고    scopus 로고
    • TLR4, TLR9 and MyD88 are not required for the positive selection of autoreactive B cells into the primary repertoire
    • Silver, K., H. Ferry, T. Crockford, and R. J. Cornall. 2006. TLR4, TLR9 and MyD88 are not required for the positive selection of autoreactive B cells into the primary repertoire. Eur. J. Immunol. 36: 1404-1412.
    • (2006) Eur. J. Immunol , vol.36 , pp. 1404-1412
    • Silver, K.1    Ferry, H.2    Crockford, T.3    Cornall, R.J.4
  • 36
    • 0029965138 scopus 로고    scopus 로고
    • Balancing immunity and tolerance: Deleting and tuning lymphocyte repertoires
    • Goodnow, C. C. 1996. Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires. Proc. Natl. Acad. Sci. USA 93: 2264-2271.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 2264-2271
    • Goodnow, C.C.1
  • 38
    • 0025184095 scopus 로고
    • Lack of N regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequences
    • Feeney, A. I. 1990. Lack of N regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequences. J. Exp. Med. 172: 1377-1390.
    • (1990) J. Exp. Med , vol.172 , pp. 1377-1390
    • Feeney, A.I.1
  • 39
    • 0026321708 scopus 로고
    • Predominance of the prototypic T15 anti-phosphorylcholine junctional sequence in neonatal pre-B cells
    • Feeney, A. J. 1991. Predominance of the prototypic T15 anti-phosphorylcholine junctional sequence in neonatal pre-B cells. J. Immunol. 147: 4343-4350.
    • (1991) J. Immunol , vol.147 , pp. 4343-4350
    • Feeney, A.J.1
  • 40
    • 0032445137 scopus 로고    scopus 로고
    • A critical role of natural immunoglobulin M in immediate defense against systemic bacterial infection
    • Boes, M., A. P. Prodeus, T. Schmidt, M. C. Carroll, and J. Chen. 1998. A critical role of natural immunoglobulin M in immediate defense against systemic bacterial infection. J. Exp. Med. 188: 2381-2386.
    • (1998) J. Exp. Med , vol.188 , pp. 2381-2386
    • Boes, M.1    Prodeus, A.P.2    Schmidt, T.3    Carroll, M.C.4    Chen, J.5
  • 41
    • 0032544110 scopus 로고    scopus 로고
    • Targeted gene disruption reveals a role for natural secretory IgM in the maturation of the primary immune response
    • Ehrenstein, M. R., T. L. O'Keefe, S. L. Davies, and M. S. Neuberger. 1998. Targeted gene disruption reveals a role for natural secretory IgM in the maturation of the primary immune response. Proc. Natl. Acad. Sci. USA 95: 10089-10093.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 10089-10093
    • Ehrenstein, M.R.1    O'Keefe, T.L.2    Davies, S.L.3    Neuberger, M.S.4
  • 42
    • 16344379409 scopus 로고    scopus 로고
    • Natural antibodies and the autoimmunity of atherosclerosis
    • Binder, C. J., and G. J. Silverman. 2005. Natural antibodies and the autoimmunity of atherosclerosis. Springer Semin. Immunopathol. 26: 385-404.
    • (2005) Springer Semin. Immunopathol , vol.26 , pp. 385-404
    • Binder, C.J.1    Silverman, G.J.2
  • 43
    • 0037942895 scopus 로고    scopus 로고
    • The autoreactivity of anti-phosphorylcholine antibodies for atherosclerosis-associated neo-antigens and apoptotic cells
    • Shaw, P. X., C. S. Goodyear, M. K. Chang, J. L. Witztum, and G. J. Silverman. 2003. The autoreactivity of anti-phosphorylcholine antibodies for atherosclerosis-associated neo-antigens and apoptotic cells. J. Immunol. 170: 6151-6157.
    • (2003) J. Immunol , vol.170 , pp. 6151-6157
    • Shaw, P.X.1    Goodyear, C.S.2    Chang, M.K.3    Witztum, J.L.4    Silverman, G.J.5
  • 44
    • 0342939538 scopus 로고    scopus 로고
    • Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity
    • Shaw, P. X., S. Horkko, M. K. Chang, L. K. Curtiss, W. Palinski, G. J. Silverman, and J. L. Witztum. 2000. Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity. J. Clin. Invest. 105: 1731-1740.
    • (2000) J. Clin. Invest , vol.105 , pp. 1731-1740
    • Shaw, P.X.1    Horkko, S.2    Chang, M.K.3    Curtiss, L.K.4    Palinski, W.5    Silverman, G.J.6    Witztum, J.L.7
  • 45
    • 0036719167 scopus 로고    scopus 로고
    • 2 activation during apoptosis promotes the exposure of membrane lysophosphatidylcholine leading to binding by natural immunoglobulin M antibodies and complement activation
    • 2 activation during apoptosis promotes the exposure of membrane lysophosphatidylcholine leading to binding by natural immunoglobulin M antibodies and complement activation. J. Exp. Med. 196: 655-665.
    • (2002) J. Exp. Med , vol.196 , pp. 655-665
    • Kim, S.J.1    Gershov, D.2    Ma, X.3    Brot, N.4    Elkon, K.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.