Charged residues between the selectivity filter and S6 segments contribute to the permeation phenotype of the sodium channel

Journal of General Physiology

Volumn 115, Issue 1, 2000, Pages 81-92

  Li, Ronald A ^a   Vélez, Patricio ^a,b   Chiamvimonvat, Nipavan ^a,c   Tomaselli, Gordon F ^a   Marbán, Eduardo ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSIDAD DE VALPARAÍSO   (Chile)

^c UNIVERSITY OF CINCINNATI   (United States)

Author keywords

Cysteine mutagenesis; Outer pore; Single channel recording; Sodium channel; Sulfhydryl modification

Indexed keywords

AMINO ACID; CYSTEINE; SODIUM CHANNEL; THIOMESYLIC ACID METHYL ESTER;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CHANNEL GATING; CONDUCTANCE; FILTER; ION PERMEABILITY; MUTAGENESIS; NONHUMAN; PROTEIN DOMAIN; RAT;

ANIMALS; ETHYL METHANESULFONATE; INDICATORS AND REAGENTS; ION CHANNEL GATING; MUTAGENESIS; PHENOTYPE; SODIUM CHANNELS;

EID: 0343158254     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.115.1.81     Document Type: Article

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