M Protein of the Group A Streptococcus Binds to the Seventh Short Consensus Repeat of Human Complement Factor H

Infection and Immunity

Volumn 66, Issue 4, 1998, Pages 1427-1431

  Blackmore, Timothy K ^a,c   Fischetti, Vincent A ^b   Sadlon, Tania A ^a   Ward, Helena M ^a   Gordon, David L ^a  

^a FLINDERS UNIVERSITY   (Australia)

^b ROCKEFELLER UNIVERSITY   (United States)

^c FLINDERS MEDICAL CENTRE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL PROTEIN; CARRIER PROTEIN; COMPLEMENT FACTOR H; COMPLEMENT FACTOR H, HUMAN; HEPARIN; OUTER MEMBRANE PROTEIN; STREPTOCOCCAL M PROTEIN;

ANIMAL; ARTICLE; BINDING SITE; CHEMISTRY; CHO CELL; HAMSTER; HUMAN; IMMUNOLOGY; METABOLISM; STREPTOCOCCUS PYOGENES;

ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL PROTEINS; BINDING SITES; CARRIER PROTEINS; CHO CELLS; COMPLEMENT FACTOR H; CRICETINAE; HEPARIN; HUMANS; STREPTOCOCCUS PYOGENES;

EID: 0032038665     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.4.1427-1431.1998     Document Type: Article

References (37)

1. Avery, V. M., and D. L. Gordon. 1993. Characterization of factor H binding to human polymorphonuclear leukocytes. J. Immunol. 151:5545-5553.
2. Barlow, P. N., and I. D. Campbell. 1994. Strategy for studying modular proteins: application to complement modules. Methods Enzymol. 239:465-485.
3. Bisno, A. L. 1979. Alternate complement pathway activation by group A streptococci: role of M protein. Infect. Immun. 26:1172-1176.
4. Bisno, A. L., and D. L. Stevens. 1996. Streptococcal infections of skin and soft tissues. N. Engl. J. Med. 334:240-245.
5. Blackmore, T. K., J. Hellwage, P. F. Zipfel, and D. L. Gordon. 1997. Identification of an additional heparin binding domain in the C-terminal region of human factor H. Exp. Clin. Immunogenet. 14:30.
6. Blackmore, T. K., T. A. Sadlon, H. M. Ward, D. M. Lublin, and D. L. Gordon. 1996. Identification of a heparin binding domain in the seventh short consensus repeat of complement factor H. J. Immunol. 157:5422-5427.
7. Brown, E. J., K. A. Joiner, T. A. Gaither, C. Hammer, and M. M. Frank. 1983. The interaction of C3b bound to pneumococci with factor H (β1H globulin), factor I (C3b/C4b inactivator) and properdin factor B of the human complement system. J. Immunol. 131:409-415.
8. Curtis, N., 1996. Invasive group A streptococcal infection. Curr. Opin. Infect. Dis. 9:191-202.
9. Edwards, M. S., D. L. Kasper, H. J. Jennings, C. J. Baker, and A. Nicholson-Weller. 1982. Capsular sialic acid prevents activation of the alternative complement pathway by type III, group B streptococci. J. Immunol. 128:1278-1283.
10. Fearon, D. T. 1978. Regulation by membrane sialic acid of β1H-dependent decay-dissociation of amplification C3 convertase of the alternative complement pathway. Proc. Natl. Acad. Sci. USA 75:1971-1975.
11. Fischetti, V. A., R. D. Horstmann, and V. Pancholi. 1995. Location of the complement factor H binding site on streptococcal M6 protein. Infect. Immun. 63:149-153.
12. Fischetti, V. A., K. F. Jones, B. N. Manjula, and J. R. Scott. 1984. Streptococcal M protein expressed in Escherichia coli. Localisation, purification, and comparison with streptococcal-derived M protein. J. Exp. Med. 159:1083-1095.
13. Gordon, D. L., R. M. Kaufman, T. K. Blackmore, J. Kwong, and D. M. Lublin. 1995. Identification of complement regulatory domains in human factor H. J. Immunol. 155:348-356.
14. Horstmann, R. D., H. J. Sievertsen, M. Leippe, and V. A. Fischetti. 1992. Role of fibrinogen in complement inhibition by streptococcal M protein. Infect. Immun. 60:5036-5041.
15. Horstmann, R. D., H. J. Sievertsen, J. Knochbloch, and V. A. Fischetti. 1988. Antiphagocytic activity of streptococcal M protein: selective binding of complement control protein factor H. Proc. Natl. Acad. Sci. USA 85:1657-1661.
16. Hourcade, D., V. M. Holers, and J. P. Atkinson. 1989. The regulators of complement activation (RCA) gene cluster. Adv. Immunol. 45:381-416.
17. Jacks-Weis, J., Y. Kim, and P. P. Cleary. 1982. Restricted deposition of C3 on M+ group A streptococci: correlation with resistance to phagocytosis. J. Immunol. 128:1897-1902.
18. Jones, K. F., and V. A. Fischetti. 1988. The importance of the location of antibody binding on the M6 protein for opsonization and phagocytosis of group A M6 streptococci. J. Exp. Med. 167:1114-1123.
19. Jones, K. F., B. N. Manjula, K. H. Johnston, S. K. Hollingshead, J. R. Scott, and V. A. Fischetti. 1985. Location of variable and conserved epitopes among the multiple serotypes of M protein. J. Exp. Med. 161:623-628.
20. Kasper, D. L. 1986. Bacterial capsule - old dogma and new tricks. J. Infect. Dis. 153:407-415.
21. Kühn, S., and P. F. Zipfel. 1995. The baculovirus expression vector pBSV-8His directs secretion of histidine-tagged proteins. Gene 162:225-229.
22. Kühn, S., C. Skerka, and P. F. Zipfel. 1995. Mapping of the complement regulatory domains in the human factor H-like protein 1 and in factor H. J. Immunol. 155:5663-5670.
23. Kühn, S., and P. F. Zipfel. 1996. Mapping of the domains required for decay acceleration activity of the human factor H-like protein 1 and factor H. Eur. J. Immunol. 26:2383-2387.
24. Lancefield, R. C. 1962. Current knowledge of type-specific M antigens of group A streptococci. J. Exp. Med. 89:307-313.
25. Meri, S., and M. K. Pangburn. 1990. Discrimination between activators and nonactivators of the alternative pathway of complement: regulation via a sialic acid/polyanion binding site on factor H. Proc. Natl. Acad. Sci. USA 87:3982-3986.
26. Okada, N., M. K. Liszewski, J. P. Atkinson, and M. G. Caparon. 1995. Membrane cofactor protein (CD46) is a keratinocyte receptor for the M protein of the group A streptococcus. Proc. Natl. Acad. Sci. USA 92:2489-2493.
27. Pangburn, M. K., R. D. Schreiber, and H. J. Müller-Eberhard. 1977. Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein β1H for cleavage of C3b and C4b in solution. J. Exp. Med. 146:257-270.
28. Perez-Casal, J., N. Okada, M. G. Caparon, and J. R. Scott. 1995. Role of the conserved C-repeat region of the M protein of Streptococcus pyogenes. Mol. Microbiol. 15:907-916.
29. Peterson, P. K., D. Schmeling, P. P. Cleary, B. J. Wilkinson, Y. Kim, and P. G. Quie. 1979. Inhibition of alternative complement pathway opsonisation by group A streptococcal M protein. J. Infect. Dis. 139:575-584.
30. Phillips, G. N., P. F. Flicker, C. Cohen, B. N. Manjula, and V. A. Fischetti. 1981. Streptococcal M proteins: alpha-helical coiled-coil structure and arrangement on the cell surface. Proc. Natl. Acad. Sci. USA 78:4689-4693.
31. Sharma, A. K., and M. K. Pangburn. 1997. Localization by site-directed mutagenesis of the site in human complement factor H that binds to Streptococcus pyogenes M protein. Infect. Immun. 65:484-487.
32. Soames, C. J., A. J. Day, and R. B. Sim. 1996. Prediction from sequence comparisons of residues of factor H involved in the interaction with complement component C3b. Biochem. J. 315:523-531.
33. Stollerman, G. H. 1997. Rheumatic fever. Lancet 349:935-942.
34. Swanson, J., K. C. Hsu, and E. C. Gotschlich. 1969. Electron microscopic studies on streptococci. I. M antigen. J. Exp. Med. 130:1063-1091.
35. Weiler, J. M., M. R. Daha, K. F. Austen, and D. T. Fearon. 1976. Control of the amplification convertase of complement by the plasma protein β1H. Proc. Natl. Acad. Sci. USA 73:3268-3272.
36. Weis, J. J., S. K. Law, R. P. Levine, and P. P. Cleary. 1985. Resistance to phagocytosis by group A streptococci: failure of deposited complement opsonins to interact with cellular receptors. J. Immunol. 134:500-505.
37. Whaley, K., and S. Ruddy. 1976. Modulation of the alternative complement pathway by β1H globulin. J. Exp. Med. 144:1147-1163.