Specific modulation of calmodulin activity induces a dramatic production of superoxide by alveolar macrophages

Laboratory Investigation

Volumn 84, Issue 1, 2004, Pages 29-40

  Ten Broeke, Robert ^a   Leusink Muis, Thea ^a   Hilberdink, Rogier ^a   Van Ark, Ingrid ^a   Van Den Worm, Edwin ^a   Villain, Matteo ^b,c   De Clerck, Fred ^a,d   Blalock, J Edwin ^b   Nijkamp, Frans P ^a   Folkerts, Gert ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c UNIVERSITY OF GENEVA   (Switzerland)

^d JANSSEN RESEARCH FOUNDATION   (Belgium)

Author keywords

Calcium like peptide; Calmodulin; Chemiluminescence; Macrophages; Superoxide

Indexed keywords

CALCIUM CHANNEL; CALCIUM LIKE PEPTIDE 2; CALMODULIN; DIPHENYLIODONIUM SALT; IONOMYCIN; LANTHANUM; N (6 AMINOHEXYL) 5 CHLORO 1 NAPHTHALENESULFONAMIDE; PEPTIDE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; CALCIUM; CALCIUM CHANNEL STIMULATING AGENT; CALP2 PROTEIN, SYNTHETIC; CARRIER PROTEIN; CATION; ENZYME INHIBITOR; SULFONAMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHEMOLUMINESCENCE; CONTROLLED STUDY; EOSINOPHIL; GUINEA PIG; INFLAMMATORY CELL; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; MALE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; ANIMAL; CHEMISTRY; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CALCIUM; CALCIUM CHANNEL AGONISTS; CALMODULIN; CARRIER PROTEINS; ENZYME INHIBITORS; GUINEA PIGS; MACROPHAGES, ALVEOLAR; MALE; ONIUM COMPOUNDS; PEPTIDES; SULFONAMIDES; SUPEROXIDE DISMUTASE; SUPEROXIDES;

EID: 1542293366     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/sj.labinvest.3700002     Document Type: Article

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