Novel analysis of clonal diversification in blood B cell and bone marrow plasma cell clones in immunoglobulin light chain amyloidosis

Journal of Clinical Immunology

Volumn 27, Issue 1, 2007, Pages 69-87

  Abraham, Roshini S ^a   Manske, Michelle K ^b   Zuckerman, Neta S ^c   Sohni, Abhishek ^d   Edelman, Hanna ^c   Shahaf, Gitit ^c   Timm, Michael M ^b   Dispenzieri, Angela ^a   Gertz, Morie A ^a   Mehr, Ramit ^c  

^a Mayo Clinic   (United States)

^b MAYO CLINIC   (United States)

^c BAR ILAN UNIVERSITY   (Israel)

^d UNIVERSITY OF MINNESOTA   (United States)

Author keywords

B cells; Cell differentiation; Human; Immunoglobulin light chain; Light chain amyloidosis; Plasma cells; Repertoire development

Indexed keywords

ANTIGEN; IMMUNOGLOBULIN LIGHT CHAIN;

AMYLOIDOSIS; ARTICLE; B LYMPHOCYTE; BONE MARROW; CELL CLONING; CELL LINEAGE; CLINICAL ARTICLE; CONTROLLED STUDY; GENE MUTATION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; MATHEMATICAL ANALYSIS; NUCLEOTIDE SEQUENCE; PLASMA CELL; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SOMATIC MUTATION; UNINDEXED SEQUENCE;

ALGORITHMS; AMYLOIDOSIS; BONE MARROW CELLS; CLONE CELLS; FEMALE; FLOW CYTOMETRY; GENES, IMMUNOGLOBULIN; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOPHENOTYPING; MALE; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MULTIPLE MYELOMA; PLASMA CELLS; SEQUENCE ALIGNMENT; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN;

EID: 33846862418     PISSN: 02719142     EISSN: 15732592     Source Type: Journal    
DOI: 10.1007/s10875-006-9056-9     Document Type: Article

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