Polyclonality of familial murine adenomas: Analyses of mouse chimeras with low tumor multiplicity suggest short-range interactions

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 19, 2005, Pages 6960-6965

  Thliveris, Andrew T ^a,b   Halberg, Richard B ^a   Clipson, Linda ^a   Dove, William F ^a,d   Sullivan, Ruth ^e   Washington, Mary Kay ^f   Stanhope, Stephen ^c   Newton, Michael A ^b,c  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c University of Wisconsin Madison   (United States)

^d UNIVERSITY OF WISCONSIN MADISON   (United States)

^e UNIVERSITY OF WISCONSIN MADISON   (United States)

^f VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Bayesian image reconstruction; Clonal interactions; Colon cancer; Spatial statistics; Tumorigenesis

Indexed keywords

APC PROTEIN;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BAYES THEOREM; CALCULATION; CHIMERA; COLON CANCER; COLON CARCINOGENESIS; CONTROLLED STUDY; FAMILIAL INTESTINAL ADENOMA; GENE; GENE LOCUS; GENE STRUCTURE; HOMOZYGOSITY; HYPOTHESIS; IMAGE RECONSTRUCTION; INTESTINE POLYP; MOM1 GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RANDOM COLLISION HYPOTHESIS; STATISTICAL ANALYSIS; TUMOR GROWTH; TUMOR RESISTANCE; TUMOR VOLUME;

ADENOMA; ADENOMATOUS POLYPOSIS COLI; ADENOMATOUS POLYPOSIS COLI PROTEIN; ALLELES; ANIMALS; CHIMERA; COMPUTATIONAL BIOLOGY; CROSSES, GENETIC; DISEASE PROGRESSION; GENES, APC; HOMOZYGOTE; IMMUNOHISTOCHEMISTRY; MICE; MICE, TRANSGENIC; MODELS, GENETIC; MODELS, MOLECULAR; MODELS, STATISTICAL; MUTATION; PHENOTYPE; SOFTWARE; TRANSGENES;

ANIMALIA; MURINAE;

EID: 18744409091     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0502662102     Document Type: Article

References (26)

1. Ponder, B. A. J. & Wilkinson, M. M. (1986) J. Natl. Cancer Inst. 77, 967-973.
2. Griffiths, D. F. R., Williams, D., Williams, G. T. & Williams, E. D. (1989) Br. J. Cancer 59, 385-387.
3. Fearon, E. R., Hamilton, S. R. & Vogelstein, B. (1987) Science 238, 193-197.
4. Novelli, M., Cossu, A., Oukrif, D., Quaglia, A., Lakhani, S., Poulsom, R., Sasieni, P., Carta, P., Contini, M., Pasca, A., et al. (2003) Proc. Natl. Acad. Sci. USA 100, 3311-3314.
5. Novelli, M. R., Williamson, J. A., Tomlinson, I. P. M., Elia, G., Hodgson, S. V., Talbot, I. C., Bodmer, W. F. & Wright, N. A. (1996) Science 272, 1187-1190.
6. Newton, M. A. (2005) On Estimating the Polyclonal Fraction in Lineage-Marker Studies of Tumor Origin, University of Wisconsin, Department of Statistics, Technical Report 1099 (University of Wisconsin, Madison).
7. Merritt, A. J., Gould, K. A. & Dove, W. F. (1997) Proc. Natl. Acad. Sci. USA 94, 13927-13931.
8. Gurdon, J. B., Lemaire, P. & Kato, K. (1993) Cell 75, 831-834.
9. Haigis, K. M., Hoff, P. D., White, A., Shoemaker, A. R., Halberg, R. B. & Dove, W. F. (2004) Proc. Natl. Acad. Sci. USA 101, 9769-9773.
10. Gould, K. A., Luongo, C., Moser, A. R., McNeley, M. K., Borenstein, N., Shedlovsky, A., Dove, W. F., Hong, K., Dietrich, W. F. & Lander, E. S. (1996) Genetics 144, 1777-1785.
11. Cormier, R. T., Bilger, A., Lillich, A. J., Halberg, R. B., Hong, K. H., Gould, K. A., Borenstein, N., Lander, E. S. & Dove, W. F. (2000) Oncogene 19, 3182-3192.
12. Gelman, A., Carlin, J. B., Stern, H. S. & Rubin, D. B. (2004) Bayesian Data Analysis (Chapman & Hall, Boca Raton, FL).
13. Armitage, P. (1949) Biometrika 36, 257-266.
14. Penrose, M. (2003) Random Geometric Graphs (Oxford Univ. Press, Oxford).
15. Gould, K. A. & Dove, W. F. (1996) Cell Growth Differ. 7, 1361-1368.
16. Besag, J. (1986) J. R. Stat. Soc. B 48, 259-302.
17. Liu, J. S. (2001) Monte Carlo Strategies in Scientific Computing (Springer, New York).
18. Ripley, B. D. (1977) J. R. Stat. Soc. B 39, 172-212.
19. Besag, J. (1974) J. R. Stat. Soc. B 36, 192-236.
20. Lee, D. T. & Schacter, B. J. (1983) Int. J. Comput. Information Sci. 9, 219-242.
21. Dove, W. F., Cormier, R. T., Gould, K. A., Halberg, R. B., Merritt, A. J., Newton, M. A. & Shoemaker, A. R. (1998) Philos. Trans. R. Soc. London B 353, 915-923.
22. Schmidt, G. H., Winton, D. J. & Ponder, B. A. J. (1988) Development (Cambridge, U.K.) 103, 785-790.
23. Levy, D. B., Smith, K. J., Beazer-Barclay, Y., Hamilton, S. R., Vogelstein, B. & Kinzler, K. W. (1994) Cancer Res. 54, 5953-5958.
24. Haigis, K. M. & Dove, W. F. (2003) Nat. Genet. 33, 33-39.
25. Bjerknes, M. & Cheng, H. (1999) Am. J. Pathol. 154, 1831-1834.
26. Wasan, H. S., Park, H. S., Liu, K. C., Mandir, N. K., Winnett, A., Sasieni, P., Bodmer, W. F., Goodlad, R. A. & Wright, N. A. (1998) J. Pathol. 185, 246-255.