Colossal crypts bordering colon adenomas in Apc(Min) mice express full- length Apc

American Journal of Pathology

Volumn 154, Issue 6, 1999, Pages 1831-1834

  Bjerknes, Matthew ^a   Cheng, Hazel ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOMATOUS POLYP; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLON ADENOMA; FAMILIAL DISEASE; HETEROZYGOSITY; IMMUNOFLUORESCENCE; INTESTINE CRYPT; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY;

EID: 0033028730     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)65439-9     Document Type: Article

References (20)

1. Filipe MI: Value of histochemical reactions for mucosubstances in the diagnosis of certain pathological conditions of the colon and rectum. Gut 1969, 10:577-586
2. Burdette WJ: Carcinoma of the colon and antecedent epithelium. Cancer Res 1970, 30:253-256
3. Dawson PA, Filipe MI: An ultrastructural and histochemical study of the mucous membrane adjacent to and remote from carcinoma of the colon. Cancer 1976, 37:2388-2398
4. Riddle RH, Levin B: Ultrastructure of the "transitional" mucosa adjacent to large bowel carcinoma. Cancer 1977, 40:2509-2522
5. Lawson MJ, White LM, Coyle P, Butler RN, Roberts-Thomson LC, Conyers RAJ: An assessment of proliferative and enzymatic activity in transitional mucosa adjacent to colonic cancer. Cancer 1989, 64: 1061-1066
6. Isaacson P, Attwood PRA: Failure to demonstrate specificity of the morphological and histochemical changes in mucosa adjacent to colonic carcinoma (transitional mucosa). J Clin Pathol 1979, 32:214-218
7. Jass JR, Sobin LH: Histological Typing of Intestinal Tumours, ed 2. New York, Springer-Verlag, 1989, p 3
8. Su L-K, Kinzler KW, Vogelstein B, Preisinger AC, Moser AR, Luongo C, Gould KA, Dove WF: Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene. Science 1992, 256:668-670
9. Reitmair AH, Cai J-C, Bjerknes M, Redston M, Cheng H, Pind MTL, Hay K, Mitri A, Bapat BV, Mak TW, Gallinger S: MSH2 deficiency contributes to accelerated APC mediated intestinal tumorigenesis. Cancer Res 1996, 56:2922-2926
10. Bjerknes M, Cheng H: Methods for the isolation of intact epithelium from the mouse intestine. Anal Rec 1981, 199:565-574
11. Anderson TF: Techniques for the preservation of three dimensional structure in preparing specimens for the electron microscope. Trans NY Acad Sci 1951, 13:130-134
12. Luongo C, Moser AR, Gledhill S, Dove WF: Loss of Apc + in intestinal adenomas from Min mice. Cancer Res 1994, 54:5947-5952
13. Lloyd E: Statistics, vol VI, part A: Handbook of Applicable Mathematics. Edited by Ledermann H. Toronto, John Wiley and Sons, 1984, pp 236-237
14. Bjerknes M: A test of the stochastic theory of stem cell differentiation. Biophys J 1986, 49:1223-1227
15. Totafurno J, Bjerknes M, Cheng H: The crypt cycle: crypt and villus production in the intestinal epithelium. Biophys J 1987, 52:279-294
16. Cheng H, Bjerknes M, Amar J, Gardiner G: Crypt production in normal and diseased human colonic epithelium. Anat Rec 1986, 216:44-48
17. Bjerknes M, Cheng H, Hay K, Gallinger S: APC mutation and the crypt cycle in murine and human intestine. Am J Pathol 1997, 150:833-839
18. Wasan HS, Park H-S, Liu KC, Mandir NK, Winnett A, Sasieni P, Bodmer WF, Goodlad RA, Wright NA: APC in the regulation of intestinal crypt fission. J Pathol 1998, 185:246-255
19. Wright NA, Pike C, Elia G: Induction of a novel epidermal growth factor-secreting cell lineage by mucosal ulceration in human gastrointestinal stem cells. Nature 1990, 343:82-85
20. Smith KJ, Johnson KA, Bryan TM, Hill DE, Markowitz S, Willson JKV, Petersen GM, Hamilton SR, Vogelstein B, Kinzler KW: The APC gene product in normal and tumor cells. Proc Natl Acad Sci USA 1993, 90:2846-2850