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Volumn 391, Issue 3, 2005, Pages 649-658

Amino-acid limitation induces transcription from the human C/EBPβ gene via an enhancer activity located downstream of the protein coding sequence

Author keywords

Activating transcription factor 3 (ATF3); Activating transcription factor 4 (ATF4); Amino acid response element (AARE); Basic leucine zipper (bZIP); CCAAT enhancer binding protein (C EBP); nutrient starvation

Indexed keywords

CELLS; GENES; PROTEINS; RNA;

EID: 27744505128     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20050882     Document Type: Article
Times cited : (29)

References (38)
  • 1
    • 0141453694 scopus 로고    scopus 로고
    • Fetal growth restriction and consequences for the offspring in animal models
    • Holemans, K., Aerts, L. and Van Assche, F. A. (2003) Fetal growth restriction and consequences for the offspring in animal models. J. Soc. Gynecol. Invest. 10, 392-399
    • (2003) J. Soc. Gynecol. Invest. , vol.10 , pp. 392-399
    • Holemans, K.1    Aerts, L.2    Van Assche, F.A.3
  • 4
    • 4444316887 scopus 로고    scopus 로고
    • Diets deficient in indispensable amino acids rapidly decrease the concentration of the limiting amino acid in the anterior piriform cortex of rats
    • Koehnle, T. J., Russell, M. C., Morin, A. S., Erecius, L. F. and Gietzen, D. W. (2004) Diets deficient in indispensable amino acids rapidly decrease the concentration of the limiting amino acid in the anterior piriform cortex of rats. J. Nutr. 134, 2365-2371
    • (2004) J. Nutr. , vol.134 , pp. 2365-2371
    • Koehnle, T.J.1    Russell, M.C.2    Morin, A.S.3    Erecius, L.F.4    Gietzen, D.W.5
  • 6
    • 0034282704 scopus 로고    scopus 로고
    • Activation of the human asparagine synthetase gene by the amino acid response and the endoplasmic reticulum stress response pathways occurs by common genomic elements
    • Barbosa-Tessmann, I. P., Chen, C., Zhong, C., Siu, F., Schuster, S. M., Nick, H. S. and Kilberg, M. S. (2000) Activation of the human asparagine synthetase gene by the amino acid response and the endoplasmic reticulum stress response pathways occurs by common genomic elements. J. Biol. Chem. 275, 26976-26985
    • (2000) J. Biol. Chem. , vol.275 , pp. 26976-26985
    • Barbosa-Tessmann, I.P.1    Chen, C.2    Zhong, C.3    Siu, F.4    Schuster, S.M.5    Nick, H.S.6    Kilberg, M.S.7
  • 7
    • 0033830234 scopus 로고    scopus 로고
    • Amino acids control mammalian gene transcription: Activating transcription factor 2 is essential for the amino acid responsiveness of the CHOP promoter
    • Bruhat, A., Jousse, C., Carrara, V., Reimold, A. M., Ferrara, M. and Fafournoux, P. (2000) Amino acids control mammalian gene transcription: activating transcription factor 2 is essential for the amino acid responsiveness of the CHOP promoter. Mol. Cell. Biol. 20, 7192-7204
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 7192-7204
    • Bruhat, A.1    Jousse, C.2    Carrara, V.3    Reimold, A.M.4    Ferrara, M.5    Fafournoux, P.6
  • 9
    • 7444229809 scopus 로고    scopus 로고
    • Transcriptional control of cystine/glutamate transporter gene by amino acid deprivation
    • Sato, H., Nomura, S., Maebara, K., Sato, K., Tamba, M. and Bannai, S. (2004) Transcriptional control of cystine/glutamate transporter gene by amino acid deprivation. Biochem. Biophys. Res. Commun. 325, 109-116
    • (2004) Biochem. Biophys. Res. Commun. , vol.325 , pp. 109-116
    • Sato, H.1    Nomura, S.2    Maebara, K.3    Sato, K.4    Tamba, M.5    Bannai, S.6
  • 10
    • 0038338321 scopus 로고    scopus 로고
    • Characterization of the nutrient sensing response unit in the human asparagine synthetase promoter
    • Zhong, C., Chen, C. and Kilberg, M. S. (2003) Characterization of the nutrient sensing response unit in the human asparagine synthetase promoter. Biochem. J. 372, 603-609
    • (2003) Biochem. J. , vol.372 , pp. 603-609
    • Zhong, C.1    Chen, C.2    Kilberg, M.S.3
  • 11
    • 0942265548 scopus 로고    scopus 로고
    • Transcriptional control of the human sodium-coupled neutral amino acid transporter system a gene by amino acid availability is mediated by an intronic element
    • Palii, S. S., Chen, H. and Kilberg, M. S. (2004) Transcriptional control of the human sodium-coupled neutral amino acid transporter system A gene by amino acid availability is mediated by an intronic element. J. Biol. Chem. 279, 3463-3471
    • (2004) J. Biol. Chem. , vol.279 , pp. 3463-3471
    • Palii, S.S.1    Chen, H.2    Kilberg, M.S.3
  • 12
    • 1242272070 scopus 로고    scopus 로고
    • Induction of CHOP expression by amino acid limitation requires both ATF4 expression and ATF2 phosphorylation
    • Averous, J., Bruhat, A., Jousse, C., Carraro, V., Thiel, G. and Fafournoux, P. (2004) Induction of CHOP expression by amino acid limitation requires both ATF4 expression and ATF2 phosphorylation. J. Biol. Chem. 279, 5288-5297
    • (2004) J. Biol. Chem. , vol.279 , pp. 5288-5297
    • Averous, J.1    Bruhat, A.2    Jousse, C.3    Carraro, V.4    Thiel, G.5    Fafournoux, P.6
  • 13
    • 0037025396 scopus 로고    scopus 로고
    • ATF4 is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase gene
    • Siu, F., Bain, P. J., LeBlanc-Chaffin, R., Chen, H. and Kilberg, M. S. (2002) ATF4 is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase gene. J. Biol. Chem. 277, 24120-24127
    • (2002) J. Biol. Chem. , vol.277 , pp. 24120-24127
    • Siu, F.1    Bain, P.J.2    Leblanc-Chaffin, R.3    Chen, H.4    Kilberg, M.S.5
  • 14
    • 0141866865 scopus 로고    scopus 로고
    • Amino acid deprivation and endoplasmic reticulum stress induce expression of multiple ATF3 mRNA species which, when overexpressed in HepG2 cells, modulate transcription by the human asparagine synthetase promoter
    • Pan, Y.-X., Chen, H., Siu, F. and Kilberg, M. S. (2003) Amino acid deprivation and endoplasmic reticulum stress induce expression of multiple ATF3 mRNA species which, when overexpressed in HepG2 cells, modulate transcription by the human asparagine synthetase promoter. J. Biol. Chem. 278, 38402-38412
    • (2003) J. Biol. Chem. , vol.278 , pp. 38402-38412
    • Pan, Y.-X.1    Chen, H.2    Siu, F.3    Kilberg, M.S.4
  • 16
    • 0035930599 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding protein beta (C/EBPβ) is a mediator of the nutrient sensing response pathway that activates the human asparagine synthetase gene
    • Siu, F. Y., Chen, C., Zhong, C. and Kilberg, M. S. (2001) CCAAT/enhancer-binding protein beta (C/EBPβ) is a mediator of the nutrient sensing response pathway that activates the human asparagine synthetase gene. J. Biol. Chem. 276, 48100-48107
    • (2001) J. Biol. Chem. , vol.276 , pp. 48100-48107
    • Siu, F.Y.1    Chen, C.2    Zhong, C.3    Kilberg, M.S.4
  • 17
    • 10944269132 scopus 로고    scopus 로고
    • Amino acid deprivation induces the transcription rate of the human asparagine synthetase gene through a timed program of expression and promoter binding of nutrient-responsive bZIP transcription factors as well as localized histone acetylation
    • Chen, H., Pan, Y. X., Dudenhausen, E. E. and Kilberg, M. S. (2004) Amino acid deprivation induces the transcription rate of the human asparagine synthetase gene through a timed program of expression and promoter binding of nutrient-responsive bZIP transcription factors as well as localized histone acetylation. J. Biol. Chem. 279, 50829-50839
    • (2004) J. Biol. Chem. , vol.279 , pp. 50829-50839
    • Chen, H.1    Pan, Y.X.2    Dudenhausen, E.E.3    Kilberg, M.S.4
  • 18
    • 0036683653 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding proteins: Structure, function and regulation
    • Ramji, D. P. and Foka, P. (2002) CCAAT/enhancer-binding proteins: structure, function and regulation. Biochem. J. 365, 561-575
    • (2002) Biochem. J. , vol.365 , pp. 561-575
    • Ramji, D.P.1    Foka, P.2
  • 19
    • 0033869876 scopus 로고    scopus 로고
    • Translational control of C/EBPα and C/EBPβ isoform expression
    • Calkhoven, C. F., Muller, C. and Leutz, A. (2000) Translational control of C/EBPα and C/EBPβ isoform expression. Genes Dev. 14, 1920-1932
    • (2000) Genes Dev. , vol.14 , pp. 1920-1932
    • Calkhoven, C.F.1    Muller, C.2    Leutz, A.3
  • 20
    • 0037595546 scopus 로고    scopus 로고
    • Comprehensive identification of human bZIP interactions with coiled-coil arrays
    • Newman, J. R. and Keating, A. E. (2003) Comprehensive identification of human bZIP interactions with coiled-coil arrays. Science (Washington D.C.) 300, 2097-2101
    • (2003) Science (Washington D.C.) , vol.300 , pp. 2097-2101
    • Newman, J.R.1    Keating, A.E.2
  • 21
    • 0037382539 scopus 로고    scopus 로고
    • Signal transduction in the liver: C/EBPβ modulates cell proliferation and survival
    • Buck, M. and Chojkier, M. (2003) Signal transduction in the liver: C/EBPβ modulates cell proliferation and survival. Hepatology 37, 731-738
    • (2003) Hepatology , vol.37 , pp. 731-738
    • Buck, M.1    Chojkier, M.2
  • 22
    • 0025936177 scopus 로고
    • A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA
    • Descombes, P. and Schibler, U. (1991) A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA. Cell (Cambridge, Mass.) 67, 569-579
    • (1991) Cell (Cambridge, Mass.) , vol.67 , pp. 569-579
    • Descombes, P.1    Schibler, U.2
  • 23
    • 3142545837 scopus 로고    scopus 로고
    • Human CCAAT/enhancer-binding protein beta (C/EBPβ) gene expression is activated by endoplasmic reticulum stress through an unfolded protein response element downstream of the protein coding seguence
    • Chen, C., Dudenhausen, E. E., Pan, Y., Zhong, C. and Kilberg, M. S. (2004) Human CCAAT/enhancer-binding protein beta (C/EBPβ) gene expression is activated by endoplasmic reticulum stress through an unfolded protein response element downstream of the protein coding seguence. J. Biol. Chem. 279, 27948-27956
    • (2004) J. Biol. Chem. , vol.279 , pp. 27948-27956
    • Chen, C.1    Dudenhausen, E.E.2    Pan, Y.3    Zhong, C.4    Kilberg, M.S.5
  • 24
    • 0035876432 scopus 로고    scopus 로고
    • Autoregulation enables different pathways to control CCAAT/enhancer binding protein beta (C/EBPβ) transcription
    • Niehof, M., Kubicka, S., Zender, L., Manns, M. P. and Trautwein, C. (2001) Autoregulation enables different pathways to control CCAAT/enhancer binding protein beta (C/EBPβ) transcription. J. Mol. Biol. 309, 855-868
    • (2001) J. Mol. Biol. , vol.309 , pp. 855-868
    • Niehof, M.1    Kubicka, S.2    Zender, L.3    Manns, M.P.4    Trautwein, C.5
  • 25
    • 0030054707 scopus 로고    scopus 로고
    • Effect of dietary protein restriction on liver transcription factors
    • Marten, N. W., Sladek, F. M. and Straus, D. S. (1996) Effect of dietary protein restriction on liver transcription factors. Biochem. J. 317, 361-370
    • (1996) Biochem. J. , vol.317 , pp. 361-370
    • Marten, N.W.1    Sladek, F.M.2    Straus, D.S.3
  • 26
    • 0028260451 scopus 로고
    • Effect of amino acid limitation on the expression of 19 genes in rat hepatoma cells
    • Marten, N. W., Burke, E. J., Hayden, J. M. and Straus, D. S. (1994) Effect of amino acid limitation on the expression of 19 genes in rat hepatoma cells. FASEB J. 8, 538-544
    • (1994) FASEB J. , vol.8 , pp. 538-544
    • Marten, N.W.1    Burke, E.J.2    Hayden, J.M.3    Straus, D.S.4
  • 27
    • 0035397709 scopus 로고    scopus 로고
    • Asparagine synthetase expression alone is sufficient to induce I-asparaginase resistance in MOLT-4 human leukaemia cells
    • Aslanian, A. M., Fletcher, B. S. and Kilberg, M. S. (2001) Asparagine synthetase expression alone is sufficient to induce I-asparaginase resistance in MOLT-4 human leukaemia cells. Biochem. J. 357, 321-328
    • (2001) Biochem. J. , vol.357 , pp. 321-328
    • Aslanian, A.M.1    Fletcher, B.S.2    Kilberg, M.S.3
  • 29
    • 0030814110 scopus 로고    scopus 로고
    • Amino acid limitation induces expression of CHOP, a CCAAT/enhancer binding protein-related gene, at both transcriptional and post-transcriptional levels
    • Bruhat, A., Jousse, C., Wang, X.-Z., Ron, D., Ferrara, M. and Fafournoux, P. (1997) Amino acid limitation induces expression of CHOP, a CCAAT/enhancer binding protein-related gene, at both transcriptional and post-transcriptional levels. J. Biol. Chem. 272, 17588-17593
    • (1997) J. Biol. Chem. , vol.272 , pp. 17588-17593
    • Bruhat, A.1    Jousse, C.2    Wang, X.-Z.3    Ron, D.4    Ferrara, M.5    Fafournoux, P.6
  • 30
    • 0037064083 scopus 로고    scopus 로고
    • Transcriptional activity of CCAAT/enhancer-binding proteins is controlled by a conserved inhibitory domain that is a target for sumoylation
    • Kim, J., Cantwell, C. A., Johnson, P. F., Pfarr, C. M. and Williams, S. C. (2002) Transcriptional activity of CCAAT/enhancer-binding proteins is controlled by a conserved inhibitory domain that is a target for sumoylation. J. Biol. Chem. 277, 38037-38044
    • (2002) J. Biol. Chem. , vol.277 , pp. 38037-38044
    • Kim, J.1    Cantwell, C.A.2    Johnson, P.F.3    Pfarr, C.M.4    Williams, S.C.5
  • 31
    • 0036829750 scopus 로고    scopus 로고
    • Nutritional control of mRNA stability is mediated by a conserved AU-rich element that binds the cytoplasmic shuttling protein HuR
    • Yaman, I., Fernandez, J., Sarkar, B., Schneider, R. J., Snider, M. D., Nagy, L. E. and Hatzoglou, M. (2002) Nutritional control of mRNA stability is mediated by a conserved AU-rich element that binds the cytoplasmic shuttling protein HuR. J. Biol. Chem. 277, 41539-41546
    • (2002) J. Biol. Chem. , vol.277 , pp. 41539-41546
    • Yaman, I.1    Fernandez, J.2    Sarkar, B.3    Schneider, R.J.4    Snider, M.D.5    Nagy, L.E.6    Hatzoglou, M.7
  • 32
    • 1842833391 scopus 로고    scopus 로고
    • Induction of p21 and p27 expression by amino acid deprivation of HepG2 human hepatoma cells involves mRNA stabilization
    • Leung-Pineda, V., Pan, Y., Chen, H. and Kilberg, M. S. (2004) Induction of p21 and p27 expression by amino acid deprivation of HepG2 human hepatoma cells involves mRNA stabilization. Biochem. J. 379, 79-88
    • (2004) Biochem. J. , vol.379 , pp. 79-88
    • Leung-Pineda, V.1    Pan, Y.2    Chen, H.3    Kilberg, M.S.4
  • 33
    • 0032407232 scopus 로고    scopus 로고
    • The C/EBP family of transcription factors in the liver and other organs
    • Takiguchi, M. (1998) The C/EBP family of transcription factors in the liver and other organs. Int. J. Exp. Pathol. 79, 369-391
    • (1998) Int. J. Exp. Pathol. , vol.79 , pp. 369-391
    • Takiguchi, M.1
  • 34
    • 0037073799 scopus 로고    scopus 로고
    • Differences in the molecular mechanisms involved in the transcriptional activation of the CHOP and asparagine synthetase genes in response to amino acid deprivation or activation of the unfolded protein response
    • Bruhat, A., Averous, J., Carraro, V., Zhong, C., Reimold, A. M., Kilberg, M. S. and Fafournoux, P. (2002) Differences in the molecular mechanisms involved in the transcriptional activation of the CHOP and asparagine synthetase genes in response to amino acid deprivation or activation of the unfolded protein response. J. Biol. Chem. 277, 48107-48114
    • (2002) J. Biol. Chem. , vol.277 , pp. 48107-48114
    • Bruhat, A.1    Averous, J.2    Carraro, V.3    Zhong, C.4    Reimold, A.M.5    Kilberg, M.S.6    Fafournoux, P.7
  • 35
    • 0030867942 scopus 로고    scopus 로고
    • Gadd153/Chop10, a potential target gene of the transcriptional repressor ATF3
    • Wolfgang, C. D., Chen, B. P., Martindale, J. L., Holbrook, N. J. and Hai, T. (1997) gadd153/Chop10, a potential target gene of the transcriptional repressor ATF3. Mol. Cell. Biol. 17, 6700-6707
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 6700-6707
    • Wolfgang, C.D.1    Chen, B.P.2    Martindale, J.L.3    Holbrook, N.J.4    Hai, T.5
  • 36
    • 0033118409 scopus 로고    scopus 로고
    • Complexes containing activating transcription factor (ATF)/cAMP- responsive-element-binding protein (CREB) interact with the CCAAT/enhancer- binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response
    • Fawcett, T. W., Martindale, J. L., Guyton, K. Z., Hai, T. and Holbrook, N. J. (1999) Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response. Biochem. J. 339, 135-141
    • (1999) Biochem. J. , vol.339 , pp. 135-141
    • Fawcett, T.W.1    Martindale, J.L.2    Guyton, K.Z.3    Hai, T.4    Holbrook, N.J.5
  • 37
    • 23944431858 scopus 로고    scopus 로고
    • Nutritional control of gene expression: How mammalian cells respond to amino acid limitation
    • Kilberg, M. S., Pan, Y. X., Chen, H. and Leung-Pineda, V. (2005) Nutritional control of gene expression: How mammalian cells respond to amino acid limitation. Annu. Rev. Nutr. 25, 59-55
    • (2005) Annu. Rev. Nutr. , vol.25 , pp. 59-155
    • Kilberg, M.S.1    Pan, Y.X.2    Chen, H.3    Leung-Pineda, V.4


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