Formulation of insulin-loaded polymeric nanoparticles using response surface methodology

Drug Development and Industrial Pharmacy

Volumn 31, Issue 2, 2005, Pages 179-189

  Attivi, D ^a   Wehrle, P ^b   Ubrich, N ^a   Damge, C ^b   Hoffman, M ^a   Maincent, P ^a  

^a UNIVERSITÉ DE LORRAINE   (France)

^b UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Eudragit RS; Experimental design; Insulin; Nanoparticles; PCL; Response surface methodology; W O W emulsion

Indexed keywords

EUDRAGIT RS; NANOPARTICLE; NEUTRAL INSULIN; OIL; POLYCAPROLACTONE; POLYMER; POLYVINYL ALCOHOL; WATER;

AQUEOUS SOLUTION; ARTICLE; BIODEGRADABILITY; DISPERSION; DRUG FORMULATION; DRUG RELEASE; EMULSION; ENCAPSULATION; EVAPORATION; MULTIPLE REGRESSION; PARTICLE SIZE; PH; STATISTICAL ANALYSIS; SURFACE PROPERTY; TIME; ZETA POTENTIAL;

ADMINISTRATION, ORAL; BIODEGRADATION, ENVIRONMENTAL; CHEMISTRY, PHARMACEUTICAL; HYPOGLYCEMIC AGENTS; INSULIN; MODELS, THEORETICAL; NANOSTRUCTURES; POLYESTERS;

EID: 14644393038     PISSN: 03639045     EISSN: None     Source Type: Journal    
DOI: 10.1081/DDC-200047802     Document Type: Article

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