Utility of long-term cultured human hepatocytes as an in vitro model for cytochrome P450 induction

Drug Metabolism and Disposition

Volumn 35, Issue 2, 2007, Pages 215-220

  Meneses Lorente, Georgina ^a,c   Pattison, Christine ^a   Guyomard, Claire ^b   Chesné, Christophe ^b   Heavens, Robert ^a   Watt, Alan P ^a   Sohal, Bindi ^a  

^a NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

^b Biopredic International   (France)

^c NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CLOTRIMAZOLE; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2B6; CYTOCHROME P450 2C9; CYTOCHROME P450 3A4; DEXAMETHASONE; MESSENGER RNA; OMEPRAZOLE; PHENOBARBITAL; RIFAMPICIN;

ARTICLE; CELL ISOLATION; CONTROLLED STUDY; DRUG RESEARCH; ENZYME INDUCTION; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL CULTURE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY ANALYSIS;

ARYL HYDROCARBON HYDROXYLASES; CELLS, CULTURED; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; HEPATOCYTES; HUMANS; OXIDOREDUCTASES, N-DEMETHYLATING; RNA, MESSENGER;

EID: 33846426421     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.106.009423     Document Type: Article

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