Mechanistic differences between in vitro assays for hydrazone-based small molecule inhibitors of anthrax lethal factor

Bioorganic Chemistry

Volumn 35, Issue 1, 2007, Pages 50-58

  Hanna, M Leslie ^a   Tarasow, Theodore M ^a   Perkins, Julie ^a  

^a LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

Author keywords

Anthrax; Hydrazone; Inhibitor; Lethal factor

Indexed keywords

HYDRAZONE DERIVATIVE;

ARTICLE; BACILLUS ANTHRACIS; CHEMICAL BOND; FLUORESCENCE SPECTROSCOPY; IC 50; LETHAL GENE; NONHUMAN; PRIORITY JOURNAL; ULTRAVIOLET SPECTROSCOPY;

ALDEHYDES; ANTIGENS, BACTERIAL; BACILLUS ANTHRACIS; BACTERIAL TOXINS; CATALYSIS; ENZYME INHIBITORS; HYDRAZINES; HYDRAZONES; KINETICS; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33846239375     PISSN: 00452068     EISSN: 10902120     Source Type: Journal    
DOI: 10.1016/j.bioorg.2006.07.004     Document Type: Article

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