-
1
-
-
0028221989
-
Topiramate: Preclinical evaluation of a structurally novel anticonvulsant
-
Shank RP, Gardocki JF, Vaught JL, et al. Topiramate: preclinical evaluation of a structurally novel anticonvulsant. Epilepsia. 1994;35(suppl 2):450-460.
-
(1994)
Epilepsia
, vol.35
, Issue.2 SUPPL.
, pp. 450-460
-
-
Shank, R.P.1
Gardocki, J.F.2
Vaught, J.L.3
-
2
-
-
0034074118
-
Topiramate modulates GABA-evoked currents in murine cortical neurons by a nonbenzodiazepine mechanism
-
White HS, Brown SD, Woodhead JH, Skeen GA, Wolf HH. Topiramate modulates GABA-evoked currents in murine cortical neurons by a nonbenzodiazepine mechanism. Epilepsia. 2000;41(suppl 1):S17-S20.
-
(2000)
Epilepsia
, vol.41
, Issue.1 SUPPL.
-
-
White, H.S.1
Brown, S.D.2
Woodhead, J.H.3
Skeen, G.A.4
Wolf, H.H.5
-
3
-
-
0005021549
-
Anticonvulsant activities and properties of topiramate
-
Kimishima K, Want Y, Tanabe T, et al. Anticonvulsant activities and properties of topiramate. Jpn J Pharmacol. 1992;58(suppl 1):S11P.
-
(1992)
Jpn J Pharmacol
, vol.58
, Issue.1 SUPPL.
-
-
Kimishima, K.1
Want, Y.2
Tanabe, T.3
-
4
-
-
0029899076
-
Topiramate: A potent anticonvulsant in the amygdala-kindled rat
-
Wauquier A, Zhou S. Topiramate: a potent anticonvulsant in the amygdala-kindled rat. Epilepsy Res. 1996;24:73-77.
-
(1996)
Epilepsy Res
, vol.24
, pp. 73-77
-
-
Wauquier, A.1
Zhou, S.2
-
5
-
-
0027429242
-
Anticonvulsant effect of topiramate [2,3:4,5-bis-O-(1-methylethylidene)- beta-D-fructopyranose sulfate] on amygdaloid kindled seizures in the cat
-
Nakamura F, Hiyoshi T, Kudo T, Yagi K, Seino M. Anticonvulsant effect of topiramate [2,3:4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfate] on amygdaloid kindled seizures in the cat. Jpn J Psychiatry Neurol. 1993;47:394-395.
-
(1993)
Jpn J Psychiatry Neurol
, vol.47
, pp. 394-395
-
-
Nakamura, F.1
Hiyoshi, T.2
Kudo, T.3
Yagi, K.4
Seino, M.5
-
6
-
-
0034113410
-
Anticonvulsant efficacy of topiramate in phenytoin-resistant kindled rats
-
Reissmuller E, Ebert U, Loscher W. Anticonvulsant efficacy of topiramate in phenytoin-resistant kindled rats. Epilepsia. 2000;41:372-379.
-
(2000)
Epilepsia
, vol.41
, pp. 372-379
-
-
Reissmuller, E.1
Ebert, U.2
Loscher, W.3
-
7
-
-
0342264691
-
Kindling alters the anticonvulsant efficacy of phenytoin in Wistar rats
-
Loscher W, Reissmuller E, Ebert U. Kindling alters the anticonvulsant efficacy of phenytoin in Wistar rats. Epilepsy Res. 2000;39:211-220.
-
(2000)
Epilepsy Res
, vol.39
, pp. 211-220
-
-
Loscher, W.1
Reissmuller, E.2
Ebert, U.3
-
8
-
-
0035074211
-
The process of epileptogenesis: A pathophysiological approach
-
Dalby NO, Mody I. The process of epileptogenesis: a pathophysiological approach. Curr Opin Neurol. 2001;14:187-192.
-
(2001)
Curr Opin Neurol
, vol.14
, pp. 187-192
-
-
Dalby, N.O.1
Mody, I.2
-
9
-
-
0028269623
-
Emerging insights into mechanisms of epilepsy: Implications for new antiepileptic drug development
-
Dichter MA. Emerging insights into mechanisms of epilepsy: implications for new antiepileptic drug development. Epilepsia. 1994;35(suppl 4):S51-S57.
-
(1994)
Epilepsia
, vol.35
, Issue.4 SUPPL.
-
-
Dichter, M.A.1
-
10
-
-
0028022008
-
Strategies for the development of drugs for pharmacoresistant epilepsies
-
Heinemann U, Draguhn A, Picker E, Stabel J, Zhang C.L. Strategies for the development of drugs for pharmacoresistant epilepsies. Epilepsia. 1994;35(suppl 5):S10-S21.
-
(1994)
Epilepsia
, vol.35
, Issue.5 SUPPL.
-
-
Heinemann, U.1
Draguhn, A.2
Picker, E.3
Stabel, J.4
Zhang, C.L.5
-
11
-
-
0002376924
-
General principles. Principles of antiepileptic drug action
-
Levy RH, Mattson RH, Meldrum BS, eds. New York, NY: Raven Press, Ltd.
-
Macdonald RL, Meldrum BS. General principles. Principles of antiepileptic drug action. In: Levy RH, Mattson RH, Meldrum BS, eds. Antiepileptic Drugs, 4th ed. New York, NY: Raven Press, Ltd.; 1995:61-77.
-
(1995)
Antiepileptic Drugs, 4th Ed.
, pp. 61-77
-
-
Macdonald, R.L.1
Meldrum, B.S.2
-
12
-
-
0029057901
-
Antiepileptic drug mechanisms of action
-
Macdonald RL, Kelly KM. Antiepileptic drug mechanisms of action. Epilepsia. 1995;36(suppl 2):S2-S12.
-
(1995)
Epilepsia
, vol.36
, Issue.2 SUPPL.
-
-
Macdonald, R.L.1
Kelly, K.M.2
-
14
-
-
0032481904
-
Migraine
-
Ferrari MD. Migraine. Lancet. 1998;351:1043-1051.
-
(1998)
Lancet
, vol.351
, pp. 1043-1051
-
-
Ferrari, M.D.1
-
15
-
-
0035836628
-
Mechanisms of migraine aura revealed by functional MRI in human visual cortex
-
Hadjikhani N, Sanchez Del Rio M, Wu O, et al. Mechanisms of migraine aura revealed by functional MRI in human visual cortex. Proc Natl Acad Sci USA. 2001;98:4687-4692.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 4687-4692
-
-
Hadjikhani, N.1
Sanchez Del Rio, M.2
Wu, O.3
-
16
-
-
0029847688
-
Sensitization of meningeal sensory neurons and the origin of headaches
-
Strassman AM, Raymond SA, Burstein R. Sensitization of meningeal sensory neurons and the origin of headaches. Nature. 1996;384:560-564.
-
(1996)
Nature
, vol.384
, pp. 560-564
-
-
Strassman, A.M.1
Raymond, S.A.2
Burstein, R.3
-
18
-
-
0345659224
-
Therapeutic implications of central and peripheral neurologic mechanisms in migraine
-
Waeber C, Moskowitz MA. Therapeutic implications of central and peripheral neurologic mechanisms in migraine. Neurology. 2003;61(8 suppl 4):S9-S20.
-
(2003)
Neurology
, vol.61
, Issue.8 SUPPL. 4
-
-
Waeber, C.1
Moskowitz, M.A.2
-
19
-
-
0034034180
-
An overview of the preclinical aspects of topiramate: Pharmacology, pharmacokinetics, and mechanism of action
-
Shank RP, Gardocki JF, Streeter AJ, Maryanoff BE. An overview of the preclinical aspects of topiramate: pharmacology, pharmacokinetics, and mechanism of action. Epilepsia. 2000;41(suppl 1):S3-S9.
-
(2000)
Epilepsia
, vol.41
, Issue.1 SUPPL.
-
-
Shank, R.P.1
Gardocki, J.F.2
Streeter, A.J.3
Maryanoff, B.E.4
-
20
-
-
0041451398
-
Topiramate: Mechanisms of action
-
Levy RH, Mattson RH, Meldrum BS, Perucca E, eds. Philadelphia, PA: Lippincott Williams & Wilkins
-
White HS. Topiramate: mechanisms of action. In: Levy RH, Mattson RH, Meldrum BS, Perucca E, eds. Antiepileptic Drugs, 5th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2002:719-726.
-
(2002)
Antiepileptic Drugs, 5th Ed.
, pp. 719-726
-
-
White, H.S.1
-
22
-
-
0343673858
-
Topiramate as an inhibitor of carbonic anhydrase isoenzymes
-
Dodgson SJ, Shank RP, Maryanoff BE. Topiramate as an inhibitor of carbonic anhydrase isoenzymes. Epilepsia. 2000;41(suppl 1):S35-S39.
-
(2000)
Epilepsia
, vol.41
, Issue.1 SUPPL.
-
-
Dodgson, S.J.1
Shank, R.P.2
Maryanoff, B.E.3
-
23
-
-
0036171793
-
Two new actions of topiramate: Inhibition of depolarizing GABA(A)-mediated responses and activation of a potassium conductance
-
Herrero AI, Del Olmo N, Gonzalez-Escalada JR, Solis JM. Two new actions of topiramate: inhibition of depolarizing GABA(A)-mediated responses and activation of a potassium conductance. Neuropharmacology. 2002;42:210-220.
-
(2002)
Neuropharmacology
, vol.42
, pp. 210-220
-
-
Herrero, A.I.1
Del Olmo, N.2
Gonzalez-Escalada, J.R.3
Solis, J.M.4
-
24
-
-
0030569028
-
Topiramate reduces abnormally high extracellular levels of glutamate and aspartate in the hippocampus of spontaneously epileptic rats (SER)
-
Kanda T, Kurokawa M, Tamura S, et al. Topiramate reduces abnormally high extracellular levels of glutamate and aspartate in the hippocampus of spontaneously epileptic rats (SER). Life Sci. 1996;59:1607-1616.
-
(1996)
Life Sci
, vol.59
, pp. 1607-1616
-
-
Kanda, T.1
Kurokawa, M.2
Tamura, S.3
-
25
-
-
0038727791
-
Evaluation of topiramate neuroprotective effect in severe TBI using microdialysis
-
Alves OL, Doyle AJ, Clausen T, Gilman C, Bullock R. Evaluation of topiramate neuroprotective effect in severe TBI using microdialysis. Ann N Y Acad Sci. 2003;993:25-34; discussion, 48-53.
-
(2003)
Ann N Y Acad Sci
, vol.993
, pp. 25-34
-
-
Alves, O.L.1
Doyle, A.J.2
Clausen, T.3
Gilman, C.4
Bullock, R.5
-
26
-
-
0034040285
-
Effects of topiramate on sodium-dependent action-potential firing by mouse spinal cord neurons in cell culture
-
McLean MJ, Bukhari AA, Wamil AW. Effects of topiramate on sodium-dependent action-potential firing by mouse spinal cord neurons in cell culture. Epilepsia. 2000;41(suppl 1):S21-S24.
-
(2000)
Epilepsia
, vol.41
, Issue.1 SUPPL.
-
-
McLean, M.J.1
Bukhari, A.A.2
Wamil, A.W.3
-
27
-
-
0030867764
-
Topiramate attenuates voltage-gated sodium currents in rat cerebellar granule cells
-
Zona C, Ciotti MT, Avoli M. Topiramate attenuates voltage-gated sodium currents in rat cerebellar granule cells. Neurosci Lett. 1997;231:123-126.
-
(1997)
Neurosci Lett
, vol.231
, pp. 123-126
-
-
Zona, C.1
Ciotti, M.T.2
Avoli, M.3
-
28
-
-
0000337336
-
Selective effects of topiramate on sustained repetitive firing and spontaneous bursting in cultured hippocampal neurons
-
Coulter DA, Sombati S, DeLorenzo RJ. Selective effects of topiramate on sustained repetitive firing and spontaneous bursting in cultured hippocampal neurons. Epilepsia. 1993;34(suppl 2):123.
-
(1993)
Epilepsia
, vol.34
, Issue.2 SUPPL.
, pp. 123
-
-
Coulter, D.A.1
Sombati, S.2
DeLorenzo, R.J.3
-
29
-
-
0002836371
-
Topiramate selectively blocks kainate currents in cultured hippocampal neurons
-
Severt L, Coulter DA, Sombati S, DeLorenzo RJ. Topiramate selectively blocks kainate currents in cultured hippocampal neurons. Epilepsia. 1995;36(suppl 4):S38.
-
(1995)
Epilepsia
, vol.36
, Issue.4 SUPPL.
-
-
Severt, L.1
Coulter, D.A.2
Sombati, S.3
DeLorenzo, R.J.4
-
30
-
-
0043127452
-
Selective antagonism of GluR5 kainate-receptor-mediated synaptic currents by topiramate in rat basolateral amygdala neurons
-
Gryder DS, Rogawski MA. Selective antagonism of GluR5 kainate-receptor-mediated synaptic currents by topiramate in rat basolateral amygdala neurons. J Neurosci. 2003;23:7069-7074.
-
(2003)
J Neurosci
, vol.23
, pp. 7069-7074
-
-
Gryder, D.S.1
Rogawski, M.A.2
-
31
-
-
0038059133
-
Topiramate protects against glutamate-and kainate-induced neurotoxicity in primary neuronal-astroglial cultures
-
Angehagen M, Ben-Menachem E, Ronnback L, Hansson E. Topiramate protects against glutamate-and kainate-induced neurotoxicity in primary neuronal-astroglial cultures. Epilepsy Res. 2003;54:63-71.
-
(2003)
Epilepsy Res
, vol.54
, pp. 63-71
-
-
Angehagen, M.1
Ben-Menachem, E.2
Ronnback, L.3
Hansson, E.4
-
32
-
-
0442328037
-
Modulation by topiramate of AMPA and kainate mediated calcium influx in cultured cerebral cortical, hippocampal and cerebellar neurons
-
Poulsen CF, Simeone TA, Maar TE, Smith-Swintosky V, White HS, Schousboe A. Modulation by topiramate of AMPA and kainate mediated calcium influx in cultured cerebral cortical, hippocampal and cerebellar neurons. Neurochem Res. 2004;29:275-282.
-
(2004)
Neurochem Res
, vol.29
, pp. 275-282
-
-
Poulsen, C.F.1
Simeone, T.A.2
Maar, T.E.3
Smith-Swintosky, V.4
White, H.S.5
Schousboe, A.6
-
33
-
-
0343673859
-
Topiramate blocks kainate-evoked cobalt influx into cultured neurons
-
Skradski S, White HS. Topiramate blocks kainate-evoked cobalt influx into cultured neurons. Epilepsia. 2000;41(suppl 1):S45-S47.
-
(2000)
Epilepsia
, vol.41
, Issue.1 SUPPL.
-
-
Skradski, S.1
White, H.S.2
-
34
-
-
0041324715
-
Topiramate alters excitatory synaptic transmission in mouse hippocampus
-
Qian J, Noebels JL. Topiramate alters excitatory synaptic transmission in mouse hippocampus. Epilepsy Res. 2003;55:225-233.
-
(2003)
Epilepsy Res
, vol.55
, pp. 225-233
-
-
Qian, J.1
Noebels, J.L.2
-
35
-
-
1942436861
-
Topiramate selectively protects against seizures induced by ATPA, a GluR5 kainate receptor agonist
-
Kaminski RM, Banerjee M, Rogawski MA. Topiramate selectively protects against seizures induced by ATPA, a GluR5 kainate receptor agonist. Neuropharmacology. 2004;46:1097-1104.
-
(2004)
Neuropharmacology
, vol.46
, pp. 1097-1104
-
-
Kaminski, R.M.1
Banerjee, M.2
Rogawski, M.A.3
-
36
-
-
0000337340
-
The novel anticonvulsant topiramate enhances GABA-mediated chloride flux
-
Brown SD, Wolf HH, Swinyard EA, Twyman RE, White HS. The novel anticonvulsant topiramate enhances GABA-mediated chloride flux. Epilepsia. 1993;34(suppl 2):122-123.
-
(1993)
Epilepsia
, vol.34
, Issue.2 SUPPL.
, pp. 122-123
-
-
Brown, S.D.1
Wolf, H.H.2
Swinyard, E.A.3
Twyman, R.E.4
White, H.S.5
-
37
-
-
0002394897
-
The anticonvulsant topiramate displays a unique ability to potentiate GABA-evoked chloride currents
-
White HS, Brown D, Skeen GA, Wolf HH, Twyman RE. The anticonvulsant topiramate displays a unique ability to potentiate GABA-evoked chloride currents. Epilepsia. 1995;36(suppl 3):S39-S40.
-
(1995)
Epilepsia
, vol.36
, Issue.3 SUPPL.
-
-
White, H.S.1
Brown, D.2
Skeen, G.A.3
Wolf, H.H.4
Twyman, R.E.5
-
38
-
-
17244370036
-
Direct activation of the recombinant a2b2g2S GABAA receptor by the novel anticonvulsant topiramate
-
Simeone TA, McClellan AML, Twyman RE, White HS. Direct activation of the recombinant a2b2g2S GABAA receptor by the novel anticonvulsant topiramate [abstract]. Soc Neurosci. 2002;26:631.
-
(2002)
Soc Neurosci
, vol.26
, pp. 631
-
-
Simeone, T.A.1
McClellan, A.M.L.2
Twyman, R.E.3
White, H.S.4
-
39
-
-
0034119079
-
Differential sensitivity of recombinant GABA(A) receptors expressed in Xenopus oocytes to modulation by topiramate
-
Gordey M, DeLorey TM, Olsen RW. Differential sensitivity of recombinant GABA(A) receptors expressed in Xenopus oocytes to modulation by topiramate. Epilepsia. 2000;41(suppl 1):S25-S29.
-
(2000)
Epilepsia
, vol.41
, Issue.1 SUPPL.
-
-
Gordey, M.1
DeLorey, T.M.2
Olsen, R.W.3
-
40
-
-
0030758984
-
Topiramate enhances GABA-mediated chloride flux and GABA-evoked chloride currents in murine brain neurons and increases seizure threshold
-
White HS, Brown SD, Woodhead JH, Skeen GA, Wolf HH. Topiramate enhances GABA-mediated chloride flux and GABA-evoked chloride currents in murine brain neurons and increases seizure threshold. Epilepsy Res. 1997;28:167-179.
-
(1997)
Epilepsy Res
, vol.28
, pp. 167-179
-
-
White, H.S.1
Brown, S.D.2
Woodhead, J.H.3
Skeen, G.A.4
Wolf, H.H.5
-
41
-
-
0026742204
-
A neuropharmacological evaluation of felbamate as a novel anticonvulsant
-
White HS, Wolf HH, Swinyard EA, Skeen GA, Sofia RD. A neuropharmacological evaluation of felbamate as a novel anticonvulsant. Epilepsia. 1992;33:564-572.
-
(1992)
Epilepsia
, vol.33
, pp. 564-572
-
-
White, H.S.1
Wolf, H.H.2
Swinyard, E.A.3
Skeen, G.A.4
Sofia, R.D.5
-
42
-
-
0033011122
-
Topiramate increases brain GABA, homocarnosine, and pyrrolidinone in patients with epilepsy
-
Petroff OA, Hyder F, Mattson RH, Rothman DL. Topiramate increases brain GABA, homocarnosine, and pyrrolidinone in patients with epilepsy. Neurology. 1999;52:473-478.
-
(1999)
Neurology
, vol.52
, pp. 473-478
-
-
Petroff, O.A.1
Hyder, F.2
Mattson, R.H.3
Rothman, D.L.4
-
43
-
-
0034087350
-
Concentration-effect studies with topiramate on selected enzymes and intermediates of the GABA shunt
-
Sills GJ, Leach JP, Kilpatrick WS, Fraser CM, Thompson GG, Brodie MJ. Concentration-effect studies with topiramate on selected enzymes and intermediates of the GABA shunt. Epilepsia. 2000;41(suppl 1):S30-S34.
-
(2000)
Epilepsia
, vol.41
, Issue.1 SUPPL.
-
-
Sills, G.J.1
Leach, J.P.2
Kilpatrick, W.S.3
Fraser, C.M.4
Thompson, G.G.5
Brodie, M.J.6
-
44
-
-
0034076789
-
Modulation of high-voltage-activated calcium channels in dentate granule cells by topiramate
-
Zhang X, Velumian AA, Jones OT, Carlen PL. Modulation of high-voltage-activated calcium channels in dentate granule cells by topiramate. Epilepsia. 2000;41(suppl 1):S52-S60.
-
(2000)
Epilepsia
, vol.41
, Issue.1 SUPPL.
-
-
Zhang, X.1
Velumian, A.A.2
Jones, O.T.3
Carlen, P.L.4
-
45
-
-
1642397435
-
Nifedipine affects the anticonvulsant activity of topiramate in various animal models of epilepsy
-
Russo E, Constanti A, Ferreri G, Citraro R, De Sarro G. Nifedipine affects the anticonvulsant activity of topiramate in various animal models of epilepsy. Neuropharmacology. 2004;46:865-878.
-
(2004)
Neuropharmacology
, vol.46
, pp. 865-878
-
-
Russo, E.1
Constanti, A.2
Ferreri, G.3
Citraro, R.4
De Sarro, G.5
-
46
-
-
0029671353
-
2 on excitatory transmission apparently caused by changes in intracellular pH in the rat hippocampal slice
-
2 on excitatory transmission apparently caused by changes in intracellular pH in the rat hippocampal slice. Brain Res. 1996;706:210-216.
-
(1996)
Brain Res
, vol.706
, pp. 210-216
-
-
Lee, J.1
Taira, T.2
Pihlaja, P.3
Ransom, B.R.4
Kaila, K.5
-
48
-
-
0034594353
-
The pharmacology of headache
-
Goadsby PJ. The pharmacology of headache. Prog Neurobiol. 2000;62:509-525.
-
(2000)
Prog Neurobiol
, vol.62
, pp. 509-525
-
-
Goadsby, P.J.1
-
49
-
-
0032981204
-
Pharmacological aspects of experimental headache models in relation to acute antimigraine therapy
-
De Vries P, Villalon CM, Saxena PR. Pharmacological aspects of experimental headache models in relation to acute antimigraine therapy. Eur J Pharmacol. 1999;375:61-74.
-
(1999)
Eur J Pharmacol
, vol.375
, pp. 61-74
-
-
De Vries, P.1
Villalon, C.M.2
Saxena, P.R.3
-
50
-
-
0344809172
-
Topiramate inhibits trigeminovascular traffic in the cat: A possible locus of action in the prevention of migraine
-
Storer RJ, Goadsby PJ. Topiramate inhibits trigeminovascular traffic in the cat: a possible locus of action in the prevention of migraine. Neurology. 2003;60(suppl 1):A238-A239.
-
(2003)
Neurology
, vol.60
, Issue.1 SUPPL.
-
-
Storer, R.J.1
Goadsby, P.J.2
|