Centrally mediated antihyperalgesic and antiallodynic effects of zonisamide following partial nerve injury in the mouse

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 372, Issue 2, 2005, Pages 107-114

  Tanabe, Mitsuo ^a   Sakaue, Akiko ^a   Takasu, Keiko ^a   Honda, Motoko ^a   Ono, Hideki ^a  

^a NAGOYA CITY UNIVERSITY   (Japan)

Author keywords

Allodynia; Antiepileptic drugs; Neuropathic pain; Nitric oxide; Thermal hyperalgesia; Zonisamide

Indexed keywords

ANTICONVULSIVE AGENT; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; ZONISAMIDE;

ALLODYNIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE MODEL; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; HYPERALGESIA; INJECTION; LOCOMOTION; MALE; MECHANICAL STIMULATION; MOTOR DYSFUNCTION; MOUSE; NERVE INJURY; NERVE LIGATION; NONHUMAN; PAIN; SCIATIC NERVE; THERMAL STIMULATION; WITHDRAWAL REFLEX;

ANIMALS; ANTIOXIDANTS; CENTRAL NERVOUS SYSTEM; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; HEAT; HYPERALGESIA; INJECTIONS, INTRAVENTRICULAR; INJECTIONS, SPINAL; ISOXAZOLES; MALE; MICE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; PAIN; PAIN THRESHOLD; SCIATIC NERVE; TIME FACTORS; TOUCH;

EID: 27144484863     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-005-0006-5     Document Type: Article

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