Immunostimulatory properties of CpG-oligonucleotides are enhanced by the use of protamine nanoparticles

Oligonucleotides

Volumn 16, Issue 4, 2006, Pages 313-322

  Kerkmann, Miren ^a   Lochmann, Dirk ^b   Weyermann, Jörg ^b   Marschner, Anja ^a   Poeck, Hendrik ^a   Wagner, Moritz ^a   Battiany, Julia ^a   Zimmer, Andreas ^c   Endres, Stefan ^a   Hartmann, Gunther ^d  

^a UNIVERSITY OF MUNICH   (Germany)

^b GOETHE UNIVERSITY   (Germany)

^c UNIVERSITY OF GRAZ   (Austria)

^d UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMATERIAL; CPG OLIGODEOXYNUCLEOTIDE; CYTOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IMMUNOSTIMULATING AGENT; INTERLEUKIN 6; NANOPARTICLE; PROTAMINE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; B LYMPHOCYTE; BIODEGRADABILITY; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; PARAMETER; PARTICLE SIZE; PERIPHERAL BLOOD MONONUCLEAR CELL; PHOTON CORRELATION SPECTROSCOPY; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; SURFACE CHARGE; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION;

ADJUVANTS, IMMUNOLOGIC; ADOLESCENT; ADULT; AGED; B-LYMPHOCYTES; BIOCOMPATIBLE MATERIALS; CYTOKINES; DENDRITIC CELLS; DRUG DELIVERY SYSTEMS; DRUG SYNERGISM; HUMANS; INTERFERON-ALPHA; INTERLEUKIN-6; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; MICROSCOPY, ELECTRON; MIDDLE AGED; NANOPARTICLES; OLIGODEOXYRIBONUCLEOTIDES; PARTICLE SIZE; PROTAMINES; SURFACE PROPERTIES;

EID: 33845950081     PISSN: 15454576     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.2006.16.313     Document Type: Article

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