Cationic polyhexylcyanoacrylate nanoparticles as carriers for antisense oligonucleotides

Antisense and Nucleic Acid Drug Development

Volumn 7, Issue 5, 1997, Pages 483-493

  Zobel, H P ^a   Kreuter, J ^a   Werner, D ^a   Noe, C R ^a   Kumel G ^a   Zimmer, A ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; CYANOACRYLATE DERIVATIVE; DEOXYRIBONUCLEASE I; DIETHYLAMINOETHYLDEXTRAN; DRUG CARRIER; FLUORESCEIN ISOTHIOCYANATE; NANOPARTICLE; PHOSPHATE; POLYMER;

ANIMAL CELL; ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; CELL CULTURE; CELL VACUOLE; CONTROLLED STUDY; CYTOPLASM; DRUG ADSORPTION; DRUG DELIVERY SYSTEM; DRUG UPTAKE; ENDOCYTOSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTERNALIZATION; IONIC STRENGTH; NONHUMAN; PH; PRIORITY JOURNAL; VERO CELL;

ANIMALIA;

EID: 0030779241     PISSN: 10872906     EISSN: None     Source Type: Journal    
DOI: 10.1089/oli.1.1997.7.483     Document Type: Article

References (5)

1. AGUILAR, L., HEMAR, A., DAUTRY-VARSAT, A., and BLUMENFELD, M. (1996). Hairpin, dumbbell, and single-stranded phosphodiester oligonucleotides exhibit identical uptake in T lymphocyte cell lines. Antisense Nucleic Acid Drug Dev. 6, 157-163.
2. AKHTAR, S., and JULIANO, R.L. (1992). Liposome delivery of antisense oligonucleotides: Adsorption and efflux characteristics of phosphorothioate oligodeoxynucleotides. J. Controlled Release 22, 47-56.
3. AUSSERER, W.A., and BIROS, M.L. (1995). High-resolution analysis and purification of synthetic oligonucleotides with strong anion-exchange HPLC. BioTechniques 19, 136-139.
4. BENNETT, R.M. (1993). As nature intended? The uptake of DNA and oligonucleotides by eukaryotic cells. Antisense Res. Dev. 3, 235-241.
5. ZHAO, Q., TEMSAMANI, J., and AGRAWAL, S. (1995). Use of cyclodextrin and its derivatives as carriers for oligonucleotide delivery. Antisense Res. Dev. 5, 185-192.