Deregulated Syk inhibits differentiation and induces growth factor-independent proliferation of pre-B cells

Journal of Experimental Medicine

Volumn 203, Issue 13, 2006, Pages 2829-2840

  Wossning, Thomas ^a,b   Herzog, Sebastian ^a,b   Köhler, Fabian ^a,b   Meixlsperger, Sonja ^a,b   Kulathu, Yogesh ^a,b   Mittler, Gerhard ^b   Abe, Akihiro ^c   Fuchs, Uta ^d   Borkhardt, Arndt ^d   Jumaa, Hassan ^a,b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^c NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR; HYBRID PROTEIN; MYC PROTEIN; PROTEIN KINASE SYK; PROTEIN KINASE SYK INHIBITOR; R 406; TRANSCRIPTION FACTOR ETV6; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; BONE MARROW; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; CELL SURVIVAL; CELL TRANSFORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; IN VITRO STUDY; LEUKEMIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADOPTIVE TRANSFER; ANIMALS; B-LYMPHOCYTES; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; DNA-BINDING PROTEINS; FUSION PROTEINS, BCR-ABL; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUKEMIA; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; OXAZINES; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PIPERAZINES; PROTEIN KINASE INHIBITORS; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-MYC; PYRIDINES; PYRIMIDINES; RECEPTORS, ANTIGEN, B-CELL; SPLEEN; TRANSFECTION;

EID: 33845907145     PISSN: 00221007     EISSN: 00221007     Source Type: Journal    
DOI: 10.1084/jem.20060967     Document Type: Article

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