Genomic and expression profiling identifies the B-cell associated tyrosine kinase Syk as a possible therapeutic target in mantle cell lymphoma

British Journal of Haematology

Volumn 132, Issue 3, 2006, Pages 303-316

  Rinaldi, Andrea ^a   Kwee, Ivo ^a,b   Taborelli, Monica ^a   Largo, Cristina ^c   Uccella, Silvia ^d   Martin, Vittoria ^d   Poretti, Giulia ^a   Gaidano, Gianluca ^e   Calabrese, Giuseppe ^f   Martinelli, Giovanni ^g   Baldini, Luca ^h   Pruneri, Giancarlo ^g   Capella, Carlo ^d   Zucca, Emanuele ^a   Cotter, Finbarr E ⁱ   Cigudosa, Juan C ^c   Catapano, Carlo V ^a   Tibiletti, Maria G ^d   Bertoni, Francesco ^a,i  

^a ONCOLOGY INSTITUTE OF SOUTHERN SWITZERLAND   (Switzerland)

^b DALLE MOLLE INSTITUTE FOR ARTIFICIAL INTELLIGENCE IDSIA   (Switzerland)

^c Centro Nacional de Investigaciones Oncológicas   (Spain)

^d UNIVERSITY OF INSUBRIA   (Italy)

^e UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^f UNIVERSITY OF CHIETI   (Italy)

^g EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^h FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

ⁱ QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

9q; Affymetrix; Isochromosome; Piceatannol; Syk

Indexed keywords

DNA; MYC PROTEIN; PICEATANNOL; PROTEIN BCL 2; PROTEIN KINASE SYK; PROTEIN KINASE SYK INHIBITOR; RNA; 3,3',4,5'-TETRAHYDROXYSTILBENE; ENZYME PRECURSOR; PROTEIN TYROSINE KINASE; SIGNAL PEPTIDE; STILBENE DERIVATIVE; TUMOR PROTEIN;

APOPTOSIS; ARTICLE; B CELL LYMPHOMA; B LYMPHOCYTE; CANCER GENETICS; CELL PROLIFERATION; CHROMOSOME 16P; CHROMOSOME 18Q; CHROMOSOME 3Q; CHROMOSOME 6P; CHROMOSOME 9Q; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DNA MICROARRAY; DRUG INHIBITION; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE DELETION; GENE MAPPING; GENE OVEREXPRESSION; GENETIC IDENTIFICATION; GENOMICS; HUMAN; HUMAN CELL; MANTLE CELL LYMPHOMA; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RECURRENT DISEASE; SIGNAL TRANSDUCTION; VALIDATION PROCESS; CELL DIVISION; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; IMMUNOHISTOCHEMISTRY; METHODOLOGY; TUMOR CELL LINE; TUMOR GENE;

APOPTOSIS; B-LYMPHOCYTES; CELL DIVISION; CELL LINE, TUMOR; DNA, NEOPLASM; ENZYME PRECURSORS; GENE DELETION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, NEOPLASM; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOMA, MANTLE-CELL; NEOPLASM PROTEINS; PROTEIN-TYROSINE KINASES; RNA, NEOPLASM; STILBENES; TRANSCRIPTION, GENETIC;

EID: 33644851486     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2005.05883.x     Document Type: Article

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