ZAP-70 tyrosine kinase is constitutively expressed and phosphorylated in B-lineage acute lymphoblastic leukemia cells

Haematologica

Volumn 90, Issue 7, 2005, Pages 899-905

  Guillaume, Nicolas ^a,c   Alleaume, Céline ^a   Munfus, Délicia ^b   Capiod, Jean Claude ^c   Touati, Gilles ^c   Pautard, Brigitte ^c   Desablens, Bernard ^c   Lefrère, Jean Jacques ^c   Gouilleux, Fabrice ^a   Lassoued, Kaiss ^a   Gouilleux Gruart, Valérie ^a  

^a INSERM   (France)

^b The University of Alabama at Birmingham   (United States)

^c AMIENS UNIVERSITY HOSPITAL   (France)

Author keywords

Acute lymphoblastic leukemia; B lymphocytes; Precursor B cells; SYK; ZAP 70

Indexed keywords

PROTEIN KINASE SYK; PROTEIN KINASE ZAP 70; TYROSINE;

ACUTE LYMPHOBLASTIC LEUKEMIA; AGED; ARTICLE; B LYMPHOCYTE; BONE MARROW; CELL FRACTIONATION; CELL LINEAGE; CHILD; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HUMAN; LEUKEMIA CELL; MALE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL; WESTERN BLOTTING;

EID: 22544437022     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Chan AC, Iwashima M, Turck CW, Weiss A. ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR ζ chain. Cell 1992;71:649-62.
2. Kane LP, Lin J, Weiss A. Signal transduction by the TCR for antigen. Curr Opin Immunol 2000;12:242-9.
3. + thymic selection in humans lacking zap-70 kinase. Cell 1994;76:947-58.
4. Negishi I, Motoyama N, Nakayama K, Nakayama K, Senju S, Hatakeyama S, et al. Essential role for ZAP-70 in both positive and negative selection of thymocytes. Nature 1995;376:435-8.
5. Chan AC, van Oers NS, Tran A, Turka L, Law CL, Ryan JC, et al. Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling. J Immunol 1994;152:4758-66.
6. Yanagi S, Inatome R, Takano T, Yamamura H. Syk expression and novel function in a wide variety of tissues. Biochem Biophys Res Commun 2001;288:495-8.
7. Schweighoffer E, Vanes L, Mathiot A, Nakamura T, Tybulewicz VL. Unexpected requirement for ZAP-70 in pre-B cell development and allelic exclusion. Immunity 2003;18:523-33.
8. Chen L, Widhopf G, Huynh L, Rassenti L, Rai KR, Weiss A, et al. Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia. Blood 2002;100:4609-14.
9. Wiestner A, Rosenwald A, Barry TS, Wright G, Davis RE, Henrickson SE, et al. ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile. Blood 2003;101:4944-51.
10. Durig J, Nuckel H, Cremer M, Fuhrer A, Halfmeyer K, Fandrey J, et al. ZAP-70 expression is a prognostic factor in chronic lymphocytic leukemia. Leukemia 2003;17:2426-34.
11. Orchard JA, Ibbotson RE, Davis Z, Wiestner A, Rosenwald A, Thomas PW, et al. ZAP-70 expression and prognosis in chronic lymphocytic leukaemia. Lancet 2004;363:105-11.
12. Bene MC, Castoldi G, Knapp W, Ludwig WD, Matutes E, Orfao A, et al. Proposals for the immunological classification of acute leukemias. European Group for the Immunological Characterization of Leukemias (EGIL). Leukemia 1995;9:1783-6.
13. Hartree EF. Determination of protein: a modification of the Lowry method that gives a linear photometric response. Anal Biochem 1972;48:422-7.
14. Leroy V, Vigan I, Mosnier JF, Dufeu-Duchesne T, Pernollet M, Zarski JP, et al. Phenotypic and functional characterization of intrahepatic T lymphocytes during chronic hepatitis C. Hepatology 2003;38:829-41.
15. Balaian L, Zhong RK, Ball ED. The inhibitory effect of anti-CD33 monoclonal antibodies on AML cell growth correlates with Syk and/or ZAP-70 expression. Exp Hematol 2003;31:363-71.
16. Goodman PA, Wood CM, Vassilev A, Mao C, Uckun FM. Spleen tyrosine kinase (Syk) deficiency in childhood pro-B cell acute lymphoblastic leukemia. Oncogene 2001;20:3969-78.
17. Pui CH, Relling MV, Downing JR. Acute lymphoblastic leukemia. N Engl J Med 2004;350:1535-48.
18. Jumaa H, Bossaller L, Portugal K, Storch B, Lotz M, Flemming A, et al. Deficiency of the adaptor SLP-65 in pre-B-cell acute lymphoblastic leukaemia. Nature 2003;423:452-6.
19. Imai C, Ross ME, Reid G, Coustan-Smith E, Schultz KR, Pui CH, et al. Expression of the adaptor protein BLNK/SLP-65 in childhood acute lymphoblastic leukemia. Leukemia 2004;18:922-5.
20. Hurwitz CA, Loken MR, Graham ML, Karp JE, Borowitz MJ, Pullen DJ, et al. Asynchronous antigen expression in B lineage acute lymphoblastic leukemia. Blood 1988;72:299-307.
21. Coopman PJ, Do MT, Barth M, Bowden ET, Hayes AJ, Basyuk E, et al. The Syk tyrosine kinase suppresses malignant growth of human breast cancer cells. Nature 2000;406:742-7.
22. Stewart ZA, Pietenpol JA. Syk: a new player in the field of breast cancer. Breast Cancer Res. 2001;3:5-7.
23. Tsubokawa M, Tohyama Y, Tohyama K, Asahi M, Inazu T, Nakamura H, et al. Interleukin-3 activates Syk in a human myeloblastic leukemia cell line, AML193. Eur J Biochem 1997;249:792-6.
24. Law CL, Sidorenko SP, Chandran KA, Draves KE, Chan AC, Weiss A, et al. Molecular cloning of human Syk. A B cell protein-tyrosine kinase associated with the surface immunoglobulin M-B cell receptor complex. J Biol Chem 1994;269:12310-9.
25. Chen L, Apgar J, Huynh L, Dicker F, Giago-McGahan T, Rassenti L, et al. ZAP-70 directly enhances IgM signaling in chronic lymphocytic leukemia. Blood 2004;1705-15.