Nanoliter microfluidic hybrid method for simultaneous screening and optimization validated with crystallization of membrane proteins

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 51, 2006, Pages 19243-19248

  Li, Ang ^a   Mustafi, Debarshi ^a   Fu, Qiang ^a   Tereshko, Valentina ^b   Chen, Delai L ^a   Tice, Joshua D ^a   Ismagilov, Rustem F ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

Droplets; High throughput; Miniaturization; Plugs; Protein structure

Indexed keywords

BACTERIAL PROTEIN; BUFFER; DETERGENT; MEMBRANE PROTEIN; REAGENT;

ARTICLE; CONCENTRATION RESPONSE; CRYSTAL STRUCTURE; CRYSTALLIZATION; DEVICE; DIFFRACTION; DILUTION; ELECTRONICS; HIGH THROUGHPUT SCREENING; MICROFLUIDICS; NANOLITER MICROFLUIDIC HYBRID METHOD; NONHUMAN; PRECIPITATION; PRIORITY JOURNAL; PROCESS OPTIMIZATION; RHODOBACTER; RHODOBACTER CAPSULATUS; RHODOBACTER VIRIDIS; SAMPLE; STRUCTURE ANALYSIS; VALIDATION PROCESS;

CRYSTALLIZATION; DETERGENTS; MEMBRANE PROTEINS; MICROFLUIDIC ANALYTICAL TECHNIQUES; MODELS, MOLECULAR; X-RAY DIFFRACTION;

EID: 33845864473     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0607502103     Document Type: Article

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