A microfluidic device for kinetic optimization of protein crystallization and in situ structure determination

Journal of the American Chemical Society

Volumn 128, Issue 10, 2006, Pages 3142-3143

  Hansen, Carl L ^a,b   Classen, Scott ^a,c   Berger, James M ^a,d   Quake, Stephen R ^a,e  

^a California Institute of Technology   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e Stanford University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CATALASE; CRYOPROTECTIVE AGENT; DIMETICONE; FERRITIN; GLYCINE; INSULIN; LYSOZYME; POLY 3,3,3 TRIFLUOROPROPYLMETHYLSILOXANE; SILOXANE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION KINETICS; CRYSTALLIZATION; DEHYDRATION; DEVICE; DIFFRACTION; MICROFLUIDICS; PROTEIN STRUCTURE; VAPOR PRESSURE; X RAY ANALYSIS;

ALDOSE-KETOSE ISOMERASES; CATALASE; CRYSTALLIZATION; KINETICS; MICROFLUIDIC ANALYTICAL TECHNIQUES; MOLECULAR STRUCTURE; MURAMIDASE; PEPTIDES; PLANT PROTEINS; PROTEINS; X-RAY DIFFRACTION;

EID: 33644962807     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0576637     Document Type: Article

References (11)

1. Hansen, C. L.; Skordalakes, E.; Berger, J. M.; Quake, S. R. Proc. Natl. Acad. Sci. U.S.A. 2002, 99, 16531-16536.
2. Hansen, C.; Sommer, M. O.; Quake, S. R. Proc. Natl. Acad Sci. U.S.A. 2004, 101, 14431-14436.
3. Zheng, B.; Roach, L. S.; Ismagilov, R. F. J. Am. Chem. Soc. 2003, 125, 11170-11171.
4. Zheng, B.; Tice, J.; Roach, L. S.; Ismagilov, R. F. Angew. Chem., Int. Ed. 2004, 43, 2508-2511.
5. Xiao, T.; Takagi, J.; Wang, J.; Springer, T. Nature 2004, 431.
6. Ferkel, J. M. Scientist 2004, 18, 44.
7. Andrew, S. P. S. Chem. Eng. Sci. 1955, 4, 269-272.
8. Merkel, T. C.; Bondar, V. I.; Nagai, K.; Freeman, B. D.; Pinnau, I. J. Polym. Sci. 2000, 38, 415-434.
9. McPherson, A. Crystallization of Biological Macromolecules, 1st ed.; Cold Spring Harbor Laboratory Press: Cold Spring Harbor, New York, 1999.
10. Luft, J. R.; DeTitta, G. T. Methods Enzymol. 1997, 276, 110-130.
11. Yadav, M. K.; Gerdts, C. J.; Sanishvili, R.; Smith, W. W.; Roach, L. S.; Ismagilov, R. F.; Kuhn, R.; Stevens, R. C. In situ data collection and structure refinement from microcapillary protein crystallization. J. Appl. Crystallogr. 2005, 38, 900-905.