-
1
-
-
0028889993
-
Autologous or allogeneic bone-marrow transplantation compared with intensive chemotherapy in acute myelogenous leukemia
-
Zittoun RA, Mandelli F, Willemze R et al (1995) Autologous or allogeneic bone-marrow transplantation compared with intensive chemotherapy in acute myelogenous leukemia. N Engl J Med 332:217-223
-
(1995)
N Engl J Med
, vol.332
, pp. 217-223
-
-
Zittoun, R.A.1
Mandelli, F.2
Willemze, R.3
-
3
-
-
0032572912
-
Acute lymphoblastic leukemia
-
Pui CH, Evans WE (1998) Acute lymphoblastic leukemia. N Engl J Med 339:605-615
-
(1998)
N Engl J Med
, vol.339
, pp. 605-615
-
-
Pui, C.H.1
Evans, W.E.2
-
4
-
-
0035166135
-
Drug resistance mechanisms in acute leukemia
-
Chauncey TR (2001) Drug resistance mechanisms in acute leukemia. Curr Opin Oncol 13:21-26
-
(2001)
Curr Opin Oncol
, vol.13
, pp. 21-26
-
-
Chauncey, T.R.1
-
5
-
-
22644445408
-
Role of multidrug resistance and its pharmacological modulation in acute myeloid leukemia
-
List AF (1996) Role of multidrug resistance and its pharmacological modulation in acute myeloid leukemia. Leukemia 10:937-942
-
(1996)
Leukemia
, vol.10
, pp. 937-942
-
-
List, A.F.1
-
6
-
-
0028100747
-
The relationship between Bcl-2 expression and response to chemotherapy in acute-leukemia
-
Maung ZT, Maclean FR, Reid MM et al (1994) The relationship between Bcl-2 expression and response to chemotherapy in acute-leukemia. Br J Haematol 88:105-109
-
(1994)
Br J Haematol
, vol.88
, pp. 105-109
-
-
Maung, Z.T.1
Maclean, F.R.2
Reid, M.M.3
-
7
-
-
0025855920
-
Mdr1 gene-expression and treatment outcome in acute myeloid-leukemia
-
Pirker R, Wallner J, Geissler K et al (1991) Mdr1 gene-expression and treatment outcome in acute myeloid-leukemia. J Natl Cancer Inst 83:708-712
-
(1991)
J Natl Cancer Inst
, vol.83
, pp. 708-712
-
-
Pirker, R.1
Wallner, J.2
Geissler, K.3
-
8
-
-
0029846602
-
Association of bcl-2, bax, bcl-xL and inteuleukin-1 beta-converting enzyme expression with initial response to chemotherapy in acute myeloid leukemia
-
Stoetzer OJ, Nussler V, Darsow M et al (1996) Association of bcl-2, bax, bcl-xL and inteuleukin-1 beta-converting enzyme expression with initial response to chemotherapy in acute myeloid leukemia. Leukemia 10:S18-S22
-
(1996)
Leukemia
, vol.10
-
-
Stoetzer, O.J.1
Nussler, V.2
Darsow, M.3
-
9
-
-
0037444287
-
Functional blocks in caspase activation pathways are common in leukemia and predict patient response to induction chemotherapy
-
Schimmer AD, Pedersen IM, Kitada S et al (2003) Functional blocks in caspase activation pathways are common in leukemia and predict patient response to induction chemotherapy. Cancer Res 63:1242-1248
-
(2003)
Cancer Res
, vol.63
, pp. 1242-1248
-
-
Schimmer, A.D.1
Pedersen, I.M.2
Kitada, S.3
-
10
-
-
0032575750
-
Caspases: Enemies within
-
Thornberry NA, Lazebnik Y (1998) Caspases: Enemies within. Science 281:1312-1316
-
(1998)
Science
, vol.281
, pp. 1312-1316
-
-
Thornberry, N.A.1
Lazebnik, Y.2
-
11
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li P, Nijhawan D, Budihardjo I et al (1997) Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91:479-489
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
-
12
-
-
0029935682
-
Involvement of the CD95 (APO-1/Fas) receptor/ligand system in drug-induced apoptosis in leukemia cells
-
Friesen C, Herr I, Krammer PH, Debatin KM (1996) Involvement of the CD95 (APO-1/Fas) receptor/ligand system in drug-induced apoptosis in leukemia cells. Nat Med 2:574-577
-
(1996)
Nat Med
, vol.2
, pp. 574-577
-
-
Friesen, C.1
Herr, I.2
Krammer, P.H.3
Debatin, K.M.4
-
13
-
-
0030656234
-
Deficient activation of the CD95 (APO-1/Fas) system in drug-resistant cells
-
Friesen C, Fulda S, Debatin KM (1997) Deficient activation of the CD95 (APO-1/Fas) system in drug-resistant cells. Leukemia 11:1833-1841
-
(1997)
Leukemia
, vol.11
, pp. 1833-1841
-
-
Friesen, C.1
Fulda, S.2
Debatin, K.M.3
-
14
-
-
0030752603
-
The CD95 (APO-1/Fas) system mediates drug-induced apoptosis in neuroblastoma cells
-
Fulda S, Sieverts H, Friesen C, Herr I, Debatin KM (1997) The CD95 (APO-1/Fas) system mediates drug-induced apoptosis in neuroblastoma cells. Cancer Res 57:3823-3829
-
(1997)
Cancer Res
, vol.57
, pp. 3823-3829
-
-
Fulda, S.1
Sieverts, H.2
Friesen, C.3
Herr, I.4
Debatin, K.M.5
-
15
-
-
0030670626
-
Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis
-
Herr I, Wilhelm D, Bohler T, Angel P, Debatin KM (1997) Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis. Embo J 16:6200-6208
-
(1997)
Embo J
, vol.16
, pp. 6200-6208
-
-
Herr, I.1
Wilhelm, D.2
Bohler, T.3
Angel, P.4
Debatin, K.M.5
-
16
-
-
0040419494
-
Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53
-
Muller M, Strand S, Hug H et al (1997) Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53. J Clin Invest 99:403-413
-
(1997)
J Clin Invest
, vol.99
, pp. 403-413
-
-
Muller, M.1
Strand, S.2
Hug, H.3
-
17
-
-
0037204948
-
TNF-R1 signaling: A beautiful pathway
-
Chen GQ, Goeddel DV (2002) TNF-R1 signaling: A beautiful pathway. Science 296:1634-1635
-
(2002)
Science
, vol.296
, pp. 1634-1635
-
-
Chen, G.Q.1
Goeddel, D.V.2
-
18
-
-
0035279153
-
Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis
-
Fulda S, Meyer E, Friesen C, Susin SA, Kroemer G, Debatin KM (2001) Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis. Oncogene 20:1063-1075
-
(2001)
Oncogene
, vol.20
, pp. 1063-1075
-
-
Fulda, S.1
Meyer, E.2
Friesen, C.3
Susin, S.A.4
Kroemer, G.5
Debatin, K.M.6
-
19
-
-
0033396491
-
Fas ligand-induced apoptosis
-
Nagata S (1999) Fas ligand-induced apoptosis. Annu Rev Genet 33:29-55
-
(1999)
Annu Rev Genet
, vol.33
, pp. 29-55
-
-
Nagata, S.1
-
20
-
-
7444272645
-
Absence or low expression of Fas-associated protein with death domain in acute myeloid leukemia cells predicts resistance to chemotherapy and poor outcome
-
Tourneur U, Delluc S, Levy V et al (2004) Absence or low expression of Fas-associated protein with death domain in acute myeloid leukemia cells predicts resistance to chemotherapy and poor outcome. Cancer Res 64:8101-8108
-
(2004)
Cancer Res
, vol.64
, pp. 8101-8108
-
-
Tourneur, U.1
Delluc, S.2
Levy, V.3
-
21
-
-
0037071388
-
Dysregulation of apoptosis genes in hematopoietic malignancies
-
Kitada S, Pedersen IM, Schimmer AD, Reed JC (2002) Dysregulation of apoptosis genes in hematopoietic malignancies. Oncogene 21:3459-3474
-
(2002)
Oncogene
, vol.21
, pp. 3459-3474
-
-
Kitada, S.1
Pedersen, I.M.2
Schimmer, A.D.3
Reed, J.C.4
-
22
-
-
0035895056
-
Receptor- and mitochondrial-mediated apoptosis in acute leukemia: A translational view
-
Schimmer AD, Hedley DW, Penn LZ, Minden MD (2001) Receptor- and mitochondrial-mediated apoptosis in acute leukemia: A translational view. Blood 98:3541-3553
-
(2001)
Blood
, vol.98
, pp. 3541-3553
-
-
Schimmer, A.D.1
Hedley, D.W.2
Penn, L.Z.3
Minden, M.D.4
-
23
-
-
0034093609
-
Role of specific apoptotic pathways in the restoration of paclitaxel-induced apoptosis by valspodar in doxorubicin-resistant MCF-7 breast cancer cells
-
Chadderton A, Villeneuve DJ, Gluck S et al (2000) Role of specific apoptotic pathways in the restoration of paclitaxel-induced apoptosis by valspodar in doxorubicin-resistant MCF-7 breast cancer cells. Breast Cancer Res Treat 59:231-244
-
(2000)
Breast Cancer Res Treat
, vol.59
, pp. 231-244
-
-
Chadderton, A.1
Villeneuve, D.J.2
Gluck, S.3
-
24
-
-
0034699330
-
Resistance to TRAIL-induced apoptosis in primitive neuroectodermal brain tumor cells correlates with a loss of caspase-8 expression
-
Grotzer MA, Eggert A, Zuzak TJ et al (2000) Resistance to TRAIL-induced apoptosis in primitive neuroectodermal brain tumor cells correlates with a loss of caspase-8 expression. Oncogene 19:4604-4610
-
(2000)
Oncogene
, vol.19
, pp. 4604-4610
-
-
Grotzer, M.A.1
Eggert, A.2
Zuzak, T.J.3
-
25
-
-
0034066405
-
Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN
-
Teitz T, Wei T, Valentine MB et al (2000) Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN. Nat Med 6:529-535
-
(2000)
Nat Med
, vol.6
, pp. 529-535
-
-
Teitz, T.1
Wei, T.2
Valentine, M.B.3
-
26
-
-
0033135406
-
Anticancer drugs induce caspase-8/FLICE activation and apoptosis in the absence of CD95 receptor/ligand interaction
-
Wesselborg S, Engels IH, Rossmann E, Los M, Schulze-Osthoff K (1999) Anticancer drugs induce caspase-8/FLICE activation and apoptosis in the absence of CD95 receptor/ligand interaction. Blood 93:3053-3063
-
(1999)
Blood
, vol.93
, pp. 3053-3063
-
-
Wesselborg, S.1
Engels, I.H.2
Rossmann, E.3
Los, M.4
Schulze-Osthoff, K.5
-
27
-
-
0030800070
-
Inhibition of death receptor signals by cellular FLIP
-
Irmler M, Thome M, Hahne M et al (1997) Inhibition of death receptor signals by cellular FLIP. Nature 388:190-195
-
(1997)
Nature
, vol.388
, pp. 190-195
-
-
Irmler, M.1
Thome, M.2
Hahne, M.3
-
28
-
-
0030970013
-
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors
-
Thome M, Schneider P, Hofmann K et al (1997) Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors. Nature 386:517-521
-
(1997)
Nature
, vol.386
, pp. 517-521
-
-
Thome, M.1
Schneider, P.2
Hofmann, K.3
-
29
-
-
0031037897
-
The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
-
Kluck RM, Bossy Wetzel E, Green DR, Newmeyer DD (1997) The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis. Science 275:1132-1136
-
(1997)
Science
, vol.275
, pp. 1132-1136
-
-
Kluck, R.M.1
Bossy Wetzel, E.2
Green, D.R.3
Newmeyer, D.D.4
-
30
-
-
0031036872
-
Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
-
Yang J, Liu XS, Bhalla K et al (1997) Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked. Science 275:1129-1132
-
(1997)
Science
, vol.275
, pp. 1129-1132
-
-
Yang, J.1
Liu, X.S.2
Bhalla, K.3
-
31
-
-
0023272413
-
Growth-Factor Requirements of Childhood Acute-Leukemia - Establishment of Gm-Csf Dependent Cell-Lines
-
Lange B, Valtieri M, Santoli D et al (1987) Growth-Factor Requirements of Childhood Acute-Leukemia - Establishment of Gm-Csf Dependent Cell-Lines. Blood 70:192-199
-
(1987)
Blood
, vol.70
, pp. 192-199
-
-
Lange, B.1
Valtieri, M.2
Santoli, D.3
-
32
-
-
0037352906
-
High susceptibility of human leukemic cells to Fas-induced apoptosis is restricted to G1 phase of the cell cycle and can be increased by interferon treatment
-
Jedema I, Barge RM, Willemze R, Falkenburg JH (2003) High susceptibility of human leukemic cells to Fas-induced apoptosis is restricted to G1 phase of the cell cycle and can be increased by interferon treatment. Leukemia 17:576-584
-
(2003)
Leukemia
, vol.17
, pp. 576-584
-
-
Jedema, I.1
Barge, R.M.2
Willemze, R.3
Falkenburg, J.H.4
-
33
-
-
1642330455
-
New CFSE-based assay to determine susceptibility to lysis by cytotoxic T cells of leukemic precursor cells within a heterogeneous target cell population
-
Jedema I, Van Der Werff NM, Barge RM, Willemze R, Falkenburg JH (2004) New CFSE-based assay to determine susceptibility to lysis by cytotoxic T cells of leukemic precursor cells within a heterogeneous target cell population. Blood 103:2677-2682
-
(2004)
Blood
, vol.103
, pp. 2677-2682
-
-
Jedema, I.1
Van Der Werff, N.M.2
Barge, R.M.3
Willemze, R.4
Falkenburg, J.H.5
-
34
-
-
0036757209
-
Deoxycytidine kinase expression and activity in patientswith resistant versus sensitive acute myeloid leukemia
-
Veuger MJT, Honders MW, Willemze R, Barge RMY (2002) Deoxycytidine kinase expression and activity in patientswith resistant versus sensitive acute myeloid leukemia. Eur J Haematol 69:171-178
-
(2002)
Eur J Haematol
, vol.69
, pp. 171-178
-
-
Veuger, M.J.T.1
Honders, M.W.2
Willemze, R.3
Barge, R.M.Y.4
-
35
-
-
0029833422
-
Episomal vectors rapidly and stably produce high-titer recombinant retrovirus
-
Kinsella TM, Nolan GP (1996) Episomal vectors rapidly and stably produce high-titer recombinant retrovirus. Hum Gene Ther 7:1405-1413
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1405-1413
-
-
Kinsella, T.M.1
Nolan, G.P.2
-
36
-
-
0035811002
-
Dual HLA class I and class II restricted recognition of alloreactive T lymphocytes mediated by a single T cell receptor complex
-
Heemskerk MHM, de Paus RA, Lurvink EGA et al (2001) Dual HLA class I and class II restricted recognition of alloreactive T lymphocytes mediated by a single T cell receptor complex. Proc Natl Acad Sci USA 98:6806-6811
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 6806-6811
-
-
Heemskerk, M.H.M.1
De Paus, R.A.2
Lurvink, E.G.A.3
-
37
-
-
16044366110
-
Colocalization of retrovirus and target cells on specific fibronectin fragments increases genetic transduction of mammalian cells
-
Hanenberg H, Xiao XL, Dilloo D, Hashino K, Kato I, Williams DA (1996) Colocalization of retrovirus and target cells on specific fibronectin fragments increases genetic transduction of mammalian cells. Nat Med 2:876-882
-
(1996)
Nat Med
, vol.2
, pp. 876-882
-
-
Hanenberg, H.1
Xiao, X.L.2
Dilloo, D.3
Hashino, K.4
Kato, I.5
Williams, D.A.6
-
38
-
-
0030868999
-
Ultraviolet radiation-induced apoptosis is mediated by activation of CD-95 (Fas/APO-1)
-
Rehemtulla A, Hamilton CA, Chinnaiyan AM, Dixit VM (1997) Ultraviolet radiation-induced apoptosis is mediated by activation of CD-95 (Fas/APO-1). J Biol Chem 272:25783-25786
-
(1997)
J Biol Chem
, vol.272
, pp. 25783-25786
-
-
Rehemtulla, A.1
Hamilton, C.A.2
Chinnaiyan, A.M.3
Dixit, V.M.4
-
39
-
-
0033583191
-
Fas ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs
-
Micheau O, Solary E, Hammann A, Dimanche-Boitrel MT (1999) Fas ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs. J Biol Chem 274:7987-7992
-
(1999)
J Biol Chem
, vol.274
, pp. 7987-7992
-
-
Micheau, O.1
Solary, E.2
Hammann, A.3
Dimanche-Boitrel, M.T.4
-
40
-
-
0031034997
-
Interaction of CED-4 with CED-3 and CED-9: A molecular framework for cell death
-
Chinnaiyan AM, ORourke K, Lane BR, Dixit VM (1997) Interaction of CED-4 with CED-3 and CED-9: A molecular framework for cell death. Science 275:1122-1126
-
(1997)
Science
, vol.275
, pp. 1122-1126
-
-
Chinnaiyan, A.M.1
ORourke, K.2
Lane, B.R.3
Dixit, V.M.4
-
41
-
-
0035736492
-
The role of caspase-8 in resistance to cancer chemotherapy
-
Kim PKM, Mahidhara R, Seol DW (2001) The role of caspase-8 in resistance to cancer chemotherapy. Drug Resist Updates 4:293-296
-
(2001)
Drug Resist Updates
, vol.4
, pp. 293-296
-
-
Kim, P.K.M.1
Mahidhara, R.2
Seol, D.W.3
|