Deficient activation of the CD95 (APO-1/Fas) system in drug-resistant cells

Leukemia

Volumn 11, Issue 11, 1997, Pages 1833-1841

  Friesen, C ^b   Fulda, S ^b   Debatin, K M ^a  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b NONE

Author keywords

Apoptosis; CD95; CD95 ligand; Drug resistance

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOHEXIMIDE; CYTARABINE; DOXORUBICIN; FAS ANTIGEN; METHOTREXATE;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CHEMOSENSITIVITY; CONTROLLED STUDY; CROSS RESISTANCE; HUMAN; HUMAN CELL; LEUKEMIA; NEUROBLASTOMA CELL; PRIORITY JOURNAL; SOLID TUMOR; TUMOR CELL;

EID: 0030656234     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2400827     Document Type: Article

References (10)

1. Barry M, Behnke CA, Eastman A. Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia. Biochem Pharmacol 1990; 40: 2353-2362.
2. Hickman JA, Potten CS, Merrit AJ, Fisher TC. Apoptosis and cancer chemotherapy. Philos Trans R Soc Lon B Biol Sci 1994; 345: 319-325.
3. Trauth BC, Klas C, Peter AMJ, Matz S, Möller P, Falk W, Debatin KM, Krammer PH. Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science 1989; 245: 301-305.
4. Debatin KM, Goldman CK, Bamford R, Waldmann TA, Krammer PH. Monoclonal antibody-mediated apoptosis in adult T cell leukemia. Lancet 1990; 335: 497-500.
5. Debatin KM, Goldman CK, Waldmann TA, Krammer PH. APO-1 induced apoptosis of leukemia cells from patients with adult T cell leukemia. Blood 1993; 81: 2972-2977.
6. Krammer PH, Dhein J, Walczak H, Behrmann I, Mariani S, Matiba B, Fath M, Daniel PT, Knipping E, Westendorp MO, Stricker K, Bäumler C, Hellbardt S, Germer M, Peter ME, Debatin KM. The role of APO-1-mediated apoptosis in the immune system. Immunol Rev 1994; 142: 175-191.
7. Oehm A, Behrmann I, Falk W, Pawlita M, Maier G, Klas C, Li-Weber M, Richards S, Dhein J, Trauth BC, Ponstingl H, Krammer PH. Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. J Biol Chem 1992; 267: 10709-10715.
8. Itoh N, Yonehara S, Ishii A, Yonehara M, Mizushima S, Sameshima M, Hase A, Seto K, Nagat S. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 1991; 66: 233-243.
9. Klas C, Debatin KM, Jonker RR, Krammer PH. Activation interferes with the apoptotic pathway in mature human T cells. Internatl Immunol 1993; 5: 625-630.
10. Kischkel FC, Hellbardt S, Behrmann I, Gremer M, Pawlita M, Krammer PH, Peter M. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins (CAP) form a death-inducing signalling complex (DISC) with the receptor. EMBO J 1995; 14: 5579-5588.